Page last updated: 2024-08-25

bexarotene and Inflammation

bexarotene has been researched along with Inflammation in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (81.82)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Athar, M; Atigadda, VR; Belyaeva, OV; Chang, PL; Chattopadhyay, D; Chou, CF; Elmets, CA; Grubbs, CJ; Kashyap, MP; Kedishvili, NY; Melo, N; Muccio, DD; Renfrow, MB; Sinha, R; Yang, Z1
Chowdhury, AS; Hung, PY; Leal, AS; Liby, KT1
Han, X; Li, Y; Wang, J; Wei, Y; Xing, Q; Zhang, P; Zhao, L1
Cheng, C; Darwazeh, R; He, J; Huang, Z; Jiang, L; Liu, H; Sun, X; Wu, J; Wu, Y; Zhang, H; Zhong, J1
Liu, D; Qu, X; Tian, JY; Tian, T; Tu, L; Wang, Q; Yang, XL; Zhang, Q1
Fujii, U; Kakuta, H; Kanehiro, A; Kataoka, M; Kiura, K; Maeda, Y; Miyahara, N; Morichika, D; Oda, N; Senoo, S; Taniguchi, A; Tanimoto, M1
Enkhjargal, B; Huang, L; Liu, F; Tang, J; Travis, ZD; Umut, O; Xu, W; Zhang, G; Zhang, JH; Zuo, Y1
Furgeson, SB; Horita, H; Lehman, AM; Montford, JR; Nemenoff, RA; Ostriker, AC; Weiser-Evans, MC1
Escudero, P; Ferrando, C; Furio, E; Gonzalez-Navarro, H; Juez, M; Navarro, A; Piqueras, L; Sanz, MJ1
Chai, DJ; Lin, JX; Lin, LM; Liu, YP; Ning, RB; Peng, F; Xu, CS1
Casali, B; Jay, TR; Lamb, R; Landreth, GE; Malm, T; Mariani, MM; Medarametla, L; Neilson, L1

Reviews

1 review(s) available for bexarotene and Inflammation

ArticleYear
Retinoid X Receptor agonists as selective modulators of the immune system for the treatment of cancer.
    Pharmacology & therapeutics, 2023, Volume: 252

    Topics: Bexarotene; Humans; Immune System; Inflammation; Neoplasms; Retinoid X Receptors; Tumor Microenvironment

2023

Other Studies

10 other study(ies) available for bexarotene and Inflammation

ArticleYear
Conformationally Defined Rexinoids for the Prevention of Inflammation and Nonmelanoma Skin Cancers.
    Journal of medicinal chemistry, 2022, 11-10, Volume: 65, Issue:21

    Topics: Humans; Inflammation; Ligands; Retinoid X Receptors; Skin Neoplasms; Tetrahydronaphthalenes; Tretinoin; Triglycerides

2022
Activation of RXR by bexarotene inhibits inflammatory conditions in human rheumatoid arthritis fibroblast‑like synoviocytes.
    International journal of molecular medicine, 2019, Volume: 44, Issue:5

    Topics: Anti-Inflammatory Agents; Apoptosis; Arthritis, Rheumatoid; Bexarotene; Cell Proliferation; Cells, Cultured; Chemokine CCL2; Cytokines; Down-Regulation; Fibroblasts; Humans; Inflammation; Interleukin-6; Interleukin-8; Matrix Metalloproteinase 3; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Retinoid X Receptors; Signal Transduction; Synoviocytes; Tumor Necrosis Factor-alpha

2019
The long non-coding RNA Neat1 is an important mediator of the therapeutic effect of bexarotene on traumatic brain injury in mice.
    Brain, behavior, and immunity, 2017, Volume: 65

    Topics: Animals; Apoptosis; Bexarotene; Brain Injuries, Traumatic; Inflammation; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Neurons; Neuroprotective Agents; RNA, Long Noncoding; Tetrahydronaphthalenes; Up-Regulation

2017
Bexarotene attenuates early brain injury via inhibiting micoglia activation through PPARγ after experimental subarachnoid hemorrhage.
    Neurological research, 2018, Volume: 40, Issue:8

    Topics: Animals; Bexarotene; Brain; Cell Death; Cytokines; Disease Models, Animal; Inflammation; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; PPAR gamma; RNA, Messenger; Subarachnoid Hemorrhage; Tetrahydronaphthalenes

2018
A retinoid X receptor partial agonist attenuates pulmonary emphysema and airway inflammation.
    Respiratory research, 2019, Jan-03, Volume: 20, Issue:1

    Topics: Animals; Bexarotene; Cigarette Smoking; Female; Inflammation; Mice; Mice, Inbred BALB C; Pulmonary Emphysema; Retinoid X Receptors

2019
Activation of retinoid X receptor by bexarotene attenuates neuroinflammation via PPARγ/SIRT6/FoxO3a pathway after subarachnoid hemorrhage in rats.
    Journal of neuroinflammation, 2019, Feb-21, Volume: 16, Issue:1

    Topics: Animals; Bexarotene; Forkhead Box Protein O3; Inflammation; Male; Neuroprotective Agents; PPAR gamma; Rats; Rats, Sprague-Dawley; Retinoid X Receptors; Signal Transduction; Sirtuins; Subarachnoid Hemorrhage

2019
Activation of the retinoid X receptor modulates angiotensin II-induced smooth muscle gene expression and inflammation in vascular smooth muscle cells.
    Molecular pharmacology, 2014, Volume: 86, Issue:5

    Topics: Actins; Angiotensin II; Animals; Bexarotene; Calcium-Binding Proteins; Calponins; Cells, Cultured; Chemokine CCL2; Gene Expression; Inflammation; Male; MAP Kinase Signaling System; Microfilament Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; PPAR gamma; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Retinoid X Receptors; Signal Transduction; Tetrahydronaphthalenes

2014
Combined treatment with bexarotene and rosuvastatin reduces angiotensin-II-induced abdominal aortic aneurysm in apoE(-/-) mice and angiogenesis.
    British journal of pharmacology, 2015, Volume: 172, Issue:12

    Topics: Angiogenesis Inhibitors; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Bexarotene; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; Phosphatidylinositol 3-Kinases; Rosuvastatin Calcium; Signal Transduction; Tetrahydronaphthalenes

2015
Coadministration of VDR and RXR agonists synergistically alleviates atherosclerosis through inhibition of oxidative stress: An in vivo and in vitro study.
    Atherosclerosis, 2016, Volume: 251

    Topics: Animals; Aorta, Thoracic; Apoptosis; Atherosclerosis; Bexarotene; Diabetes Complications; Disease Models, Animal; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Interleukin-10; Interleukin-6; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Protein Kinase C; Reactive Oxygen Species; Receptors, Calcitriol; Retinoid X Receptors; RNA, Small Interfering; Superoxide Dismutase; Tetrahydronaphthalenes

2016
Neuronally-directed effects of RXR activation in a mouse model of Alzheimer's disease.
    Scientific reports, 2017, 02-16, Volume: 7

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Bexarotene; Biomarkers; Cell Survival; Cytokines; Disease Models, Animal; Female; Gliosis; Glutamic Acid; Habituation, Psychophysiologic; Hippocampus; Inflammation; Male; Membrane Transport Proteins; Memory; Mice, Transgenic; Neurons; Neurotoxins; Olfactory Bulb; Plaque, Amyloid; Receptors, LDL; Retinoid X Receptors; Synapses; Tetrahydronaphthalenes

2017