Page last updated: 2024-08-25

bexarotene and Experimental Mammary Neoplasms

bexarotene has been researched along with Experimental Mammary Neoplasms in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (15.00)	18.2507
2000's	13 (65.00)	29.6817
2010's	4 (20.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Atigadda, VR; Boerma, LJ; Brouillette, WJ; Desphande, A; Grubbs, CJ; Lobo-Ruppert, S; Muccio, DD; Smith, CD; Xia, G	1
Atigadda, VR; Bland, KI; Brouillette, WJ; Deshpande, A; Grubbs, CJ; Kedishvili, N; Krontiras, H; Muccio, DD; Smith, CD; Wu, L; Xia, G	1
Bratescu, L; Christov, K; Green, A; Shilkaitis, A; Yamada, T	1
Baker, R; Bissonnette, RP; Brown, PH; Dannenberg, AJ; Howe, LR; Newman, RA; Salmon, AP; Subbaramaiah, K; Yang, P; Zhou, XK	1
Bissonette, R; Brown, PH; Hill, J; Hilsenbeck, SG; Kittrell, F; Medina, D; Zhang, Y	1
Abba, MC; Aldaz, CM; Bissonnette, RP; Brown, PH; Gaddis, S; Hill, J; Hu, Y; Kittrell, FS; Levy, CC; Medina, D	1
Gould, MN; Haag, JD; Sullivan, R; Woditschka, S	1
Boring, D; Grubbs, CJ; Juliana, MM; Lubet, RA; Ruppert, JM; Steele, VE	1
Bojkova, B; Kajo, K; Karsnakova, R; Kassayova, M; Kiskova, T; Kubatka, P; Nosal, V; Orendas, P; Pec, M; Stollarova, N; Zihlavnikova, K	1
Bissonette, R; Brown, PH; Celestino, J; Hill, J; Hilsenbeck, SG; Kim, HT; Lamph, WW; Mohsin, SK; Wu, K; Xu, XC; Zhang, Y	1
Lamph, WW; Prudente, RY; Yen, WC	1
Bissonnette, R; Brown, PH; Dannenberg, AJ; DeNardo, D; Hilsenbeck, SG; Kim, HT; Kong, G; Lamph, WW; Wu, K; Xu, XC	1
Brose, HL; Gould, MN; Haag, JD; Hitt, AA; Hu, R; Kim, K; Lindstrom, MJ; Lubet, RA; Mau, B; Monson, DM; Steele, VE; Waller, JL; Watson, PA; Woditschka, S; Zheng, Y	1
Bissonnette, RP; Brown, PH; Hill, J; Kim, HT; Lamph, WW; Li, Y; Shen, Q; Zhang, Y	1
Bode, AM; Christov, K; Ericson, ME; Grubbs, CJ; Juliana, MM; Lubet, RA; Steele, VE; Szabo, E	1
Bischoff, ED; Gottardis, MM; Heyman, RA; Lamph, WW; Shirley, MA; Wagoner, MA	1
Bischoff, ED; Gottardis, MM; Heyman, RA; Lamph, WW; Moon, TE	1
Bischoff, ED; Heyman, RA; Lamph, WW	1
Agarwal, VR; Bischoff, ED; Hermann, T; Lamph, WW	1
Brown, PH; Green, JE; Hilsenbeck, SG; Kim, HT; Kuhn, JG; Lamph, WW; Mohsin, SK; Rodriquez, JL; Wu, K; Xu, XC	1

Other Studies

20 other study(ies) available for bexarotene and Experimental Mammary Neoplasms

Article	Year
Methyl substitution of a rexinoid agonist improves potency and reveals site of lipid toxicity. Journal of medicinal chemistry, 2014, Jun-26, Volume: 57, Issue:12 Topics: Animals; Anticarcinogenic Agents; Apoptosis; Bexarotene; Binding Sites; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Crystallography, X-Ray; Fatty Acids, Unsaturated; Female; Humans; Hyperlipidemias; Mammary Neoplasms, Experimental; Models, Molecular; Molecular Structure; Naphthalenes; Rats; Retinoid X Receptor alpha; Stereoisomerism; Structure-Activity Relationship; Tetrahydronaphthalenes; Transcriptional Activation	2014
Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers. Journal of medicinal chemistry, 2015, Oct-08, Volume: 58, Issue:19 Topics: Animals; Anticarcinogenic Agents; Binding Sites; Chemistry Techniques, Synthetic; Crystallography, X-Ray; Dyslipidemias; Fatty Acids, Unsaturated; Female; Humans; Mammary Neoplasms, Experimental; Molecular Conformation; Naphthalenes; Rats, Sprague-Dawley; Retinoid X Receptor alpha; Structure-Activity Relationship; Tamoxifen; Triglycerides	2015
Bexarotene induces cellular senescence in MMTV-Neu mouse model of mammary carcinogenesis. Cancer prevention research (Philadelphia, Pa.), 2013, Volume: 6, Issue:4 Topics: Animals; Anticarcinogenic Agents; Bexarotene; Cell Transformation, Neoplastic; Cellular Senescence; Female; Genes, erbB-2; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Transgenic; Tetrahydronaphthalenes; Up-Regulation	2013
Combination chemoprevention of HER2/neu-induced breast cancer using a cyclooxygenase-2 inhibitor and a retinoid X receptor-selective retinoid. Cancer prevention research (Philadelphia, Pa.), 2008, Volume: 1, Issue:3 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bexarotene; Carcinoma; Celecoxib; Cell Transformation, Neoplastic; Chemoprevention; Cyclooxygenase 2 Inhibitors; Drug Evaluation, Preclinical; Eicosanoids; Female; Genes, erbB-2; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Transgenic; Pyrazoles; Retinoid X Receptors; Retinoids; Substrate Specificity; Sulfonamides; Tetrahydronaphthalenes	2008
Prevention of tumorigenesis in p53-null mammary epithelium by rexinoid bexarotene, tyrosine kinase inhibitor gefitinib, and celecoxib. Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:2 Topics: Animals; Anticarcinogenic Agents; Bexarotene; Celecoxib; Cyclooxygenase Inhibitors; Disease Models, Animal; ErbB Receptors; Female; Gefitinib; Immunoenzyme Techniques; Incidence; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Knockout; Pyrazoles; Quinazolines; Sulfonamides; Tetrahydronaphthalenes; Tumor Suppressor Protein p53	2009
Identification of modulated genes by three classes of chemopreventive agents at preneoplastic stages in a p53-null mouse mammary tumor model. Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:2 Topics: Animals; Anticarcinogenic Agents; Bexarotene; Biomarkers, Tumor; Celecoxib; Cyclooxygenase Inhibitors; Disease Models, Animal; ErbB Receptors; Female; Gefitinib; Gene Expression Profiling; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Precancerous Conditions; Pyrazoles; Quinazolines; Sulfonamides; Tetrahydronaphthalenes; Tumor Protein, Translationally-Controlled 1; Tumor Suppressor Protein p53	2009
A short-term rat mammary carcinogenesis model for the prevention of hormonally responsive and nonresponsive in situ carcinomas. Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:2 Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Apoptosis; Bexarotene; Carcinoma in Situ; Celecoxib; Cell Proliferation; Cyclooxygenase Inhibitors; Disease Models, Animal; Female; Genes, erbB-2; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Pyrazoles; Rats; Rats, Inbred WF; Retroviridae; Sulfonamides; Tamoxifen; Tetrahydronaphthalenes; Time Factors	2009
Lack of efficacy of the statins atorvastatin and lovastatin in rodent mammary carcinogenesis. Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:2 Topics: Alkylating Agents; Animals; Anticarcinogenic Agents; Anticholesteremic Agents; Antineoplastic Agents, Hormonal; Apoptosis; Atorvastatin; Bexarotene; Cell Proliferation; Diet; Disease Models, Animal; Female; Genes, erbB-2; Heptanoic Acids; Lovastatin; Mammary Neoplasms, Experimental; Methylnitrosourea; Mice; Mice, Knockout; Mice, Transgenic; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Retinoid X Receptors; Tamoxifen; Tetrahydronaphthalenes; Treatment Outcome; Tumor Suppressor Protein p53	2009
Melatonin enhanced bexarotene efficacy in experimental mammary carcinogenesis. Neoplasma, 2012, Volume: 59, Issue:4 Topics: Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Bexarotene; Carcinogens; Female; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Treatment Outcome	2012
The retinoid X receptor-selective retinoid, LGD1069, prevents the development of estrogen receptor-negative mammary tumors in transgenic mice. Cancer research, 2002, Nov-15, Volume: 62, Issue:22 Topics: Animals; Anticarcinogenic Agents; Bexarotene; Cell Division; Female; Gene Expression; Genes, erbB-2; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Transgenic; Receptors, Estrogen; Receptors, Retinoic Acid; Retinoid X Receptors; Tetrahydronaphthalenes; Transcription Factors; Transgenes	2002
Synergistic effect of a retinoid X receptor-selective ligand bexarotene (LGD1069, Targretin) and paclitaxel (Taxol) in mammary carcinoma. Breast cancer research and treatment, 2004, Volume: 88, Issue:2 Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bexarotene; Cell Death; Female; Mammary Neoplasms, Experimental; Paclitaxel; Rats; Tetrahydronaphthalenes; Tumor Cells, Cultured	2004
The retinoid X receptor-selective retinoid, LGD1069, down-regulates cyclooxygenase-2 expression in human breast cells through transcription factor crosstalk: implications for molecular-based chemoprevention. Cancer research, 2005, Apr-15, Volume: 65, Issue:8 Topics: Animals; Anticarcinogenic Agents; Bexarotene; Breast; Breast Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Down-Regulation; E1A-Associated p300 Protein; Female; Humans; Mammary Neoplasms, Experimental; Membrane Proteins; Mice; Nuclear Proteins; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Retinoid X Receptors; Substrate Specificity; Tetrahydronaphthalenes; Trans-Activators; Transcription Factor AP-1; Transcriptional Activation; Transfection	2005
Neu-induced retroviral rat mammary carcinogenesis: a novel chemoprevention model for both hormonally responsive and nonresponsive mammary carcinomas. Cancer research, 2006, Jul-01, Volume: 66, Issue:13 Topics: Animals; Anticarcinogenic Agents; Bexarotene; Body Weight; Disease Models, Animal; Female; Genes, erbB-2; Genetic Vectors; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Nicotinic Acids; Rats; Rats, Inbred WF; Retroviridae; Tamoxifen; Tetrahydronaphthalenes	2006
The rexinoid, bexarotene, prevents the development of premalignant lesions in MMTV-erbB2 mice. British journal of cancer, 2008, Apr-22, Volume: 98, Issue:8 Topics: Animals; Anticarcinogenic Agents; Basic Helix-Loop-Helix Transcription Factors; Bexarotene; Cell Proliferation; Cyclin D; Cyclins; Female; Gene Expression Profiling; Genes, erbB-2; Homeodomain Proteins; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Mice; Mice, Transgenic; Precancerous Conditions; Tetrahydronaphthalenes	2008
Effects of gefitinib (Iressa) on mammary cancers: preventive studies with varied dosages, combinations with vorozole or targretin, and biomarker changes. Molecular cancer therapeutics, 2008, Volume: 7, Issue:4 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bexarotene; Biomarkers, Tumor; Carcinogens; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Therapy, Combination; ErbB Receptors; Female; Gefitinib; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; Methylnitrosourea; Phosphorylation; Quinazolines; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Triazoles	2008
Chemoprevention of mammary carcinoma by LGD1069 (Targretin): an RXR-selective ligand. Cancer research, 1996, Dec-15, Volume: 56, Issue:24 Topics: Animals; Anticarcinogenic Agents; Bexarotene; Carcinogens; Drug Screening Assays, Antitumor; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Organ Size; Rats; Rats, Sprague-Dawley; Receptors, Retinoic Acid; Retinoid X Receptors; Tetrahydronaphthalenes; Transcription Factors; Uterus	1996
Beyond tamoxifen: the retinoid X receptor-selective ligand LGD1069 (TARGRETIN) causes complete regression of mammary carcinoma. Cancer research, 1998, Feb-01, Volume: 58, Issue:3 Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bexarotene; Cell Division; Drug Screening Assays, Antitumor; Drug Synergism; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Receptors, Retinoic Acid; Retinoid X Receptors; Tamoxifen; Tetrahydronaphthalenes; Transcription Factors	1998
Effect of the retinoid X receptor-selective ligand LGD1069 on mammary carcinoma after tamoxifen failure. Journal of the National Cancer Institute, 1999, Dec-15, Volume: 91, Issue:24 Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bexarotene; Carcinogens; Disease Progression; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Tamoxifen; Tetrahydronaphthalenes; Treatment Failure; Treatment Outcome	1999
Induction of adipocyte-specific gene expression is correlated with mammary tumor regression by the retinoid X receptor-ligand LGD1069 (targretin). Cancer research, 2000, Nov-01, Volume: 60, Issue:21 Topics: Adaptor Protein Complex 2; Adaptor Protein Complex alpha Subunits; Adaptor Proteins, Vesicular Transport; Adipocytes; Animals; Anticarcinogenic Agents; Bexarotene; Carcinogens; Cell Differentiation; Cell Division; Clone Cells; Complement Factor D; Female; Gene Expression; Growth Inhibitors; Ligands; Lipoprotein Lipase; Mammary Neoplasms, Experimental; Membrane Proteins; Methylnitrosourea; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Serine Endopeptidases; Tetrahydronaphthalenes; Transcription Factors; Tumor Cells, Cultured	2000
Suppression of mammary tumorigenesis in transgenic mice by the RXR-selective retinoid, LGD1069. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2002, Volume: 11, Issue:5 Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Benzoates; Bexarotene; Biomarkers, Tumor; Breast Neoplasms; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Growth Inhibitors; Histones; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; Sensitivity and Specificity; Tetrahydronaphthalenes; Time Factors; Transcription Factors; Treatment Outcome	2002