Page last updated: 2024-08-25

bexarotene and Breast Cancer

bexarotene has been researched along with Breast Cancer in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (13.33)	18.2507
2000's	9 (60.00)	29.6817
2010's	4 (26.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bode, AM; Chen, H; Dong, Z; Kim, JE; Kim, MS; Lim, DY; Lubet, RA	1
Chen, G; Chen, K; Fu, S; Jia, L; Jiang, X; Li, H; Li, Y; Liu, X; Ren, Y; Wang, L; Wang, S; Wu, C; Yang, J	1
Ko, SG; Seo, HS; Shin, YC; Woo, JK	1
Bieberich, E; Dasgupta, S; Dinkins, MB; He, Q; Kim, A; Kong, JN; Spassieva, S; Wang, G; Zhu, G	1
Baidas, S; Cohen, R; Demetri, GD; DeMichele, A; Dickler, M; Esteva, FJ; Glaspy, J; Hayes, DF; Hortobagyi, GN; Hutchins, L; Laufman, L; Osborne, CK; Tripathy, D; Winer, E; Yocum, RC	1
Farol, LT; Hymes, KB	1
Simeone, AM; Tari, AM	1
Hede, K	1
Bissonnette, R; Brown, PH; Dannenberg, AJ; DeNardo, D; Hilsenbeck, SG; Kim, HT; Kong, G; Lamph, WW; Wu, K; Xu, XC	1
Lamph, WW; Yen, WC	1
Bissonnette, R; Brown, PH; Denardo, D; Hilsenbeck, SG; Johnson, K; Kim, HT; Kong, G; Lamph, WW; Li, Y; Mohsin, S; Pal, S; Uray, I	1
Allegretto, EA; Chandraratna, RA; Fitzgerald, P; Heyman, RA; Teng, M	1
Budel, V; Cahen, P; Chaboteaux, C; Darro, F; Decaestecker, C; Kiss, R; Leblond, B; Nogaret, JM; Pétein, M; Pourrias, B; Ramos, C; Schoofs, A; Vianna, A	1
Cohen, MH; Flamm Honig, S; Hirschfeld, S; Ibrahim, A; Johnson, JR; O'Leary, JJ; Pazdur, R; White, RM; Williams, GA	1
Brown, PH; Green, JE; Hilsenbeck, SG; Kim, HT; Kuhn, JG; Lamph, WW; Mohsin, SK; Rodriquez, JL; Wu, K; Xu, XC	1

Reviews

2 review(s) available for bexarotene and Breast Cancer

Article	Year
Bexarotene: a clinical review. Expert review of anticancer therapy, 2004, Volume: 4, Issue:2 Topics: Anticarcinogenic Agents; Bexarotene; Breast Neoplasms; Clinical Trials as Topic; Humans; Lung Neoplasms; Lymphoma, T-Cell, Cutaneous; Neoplasms; Skin Neoplasms; Tetrahydronaphthalenes	2004
How retinoids regulate breast cancer cell proliferation and apoptosis. Cellular and molecular life sciences : CMLS, 2004, Volume: 61, Issue:12 Topics: Alitretinoin; Anticarcinogenic Agents; Apoptosis; Bexarotene; Breast Neoplasms; Cell Cycle; Cell Division; Female; Fenretinide; Humans; Retinoids; Tetrahydronaphthalenes; Tretinoin	2004

Trials

1 trial(s) available for bexarotene and Breast Cancer

Article	Year
Multicenter phase II study of oral bexarotene for patients with metastatic breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Mar-15, Volume: 21, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bexarotene; Breast Neoplasms; Disease Progression; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Estrogen Receptor Modulators; Female; Humans; Middle Aged; Receptors, Estrogen; Receptors, Progesterone; Survival Analysis; Tamoxifen; Tetrahydronaphthalenes; Thyroid Hormones; Toremifene; Treatment Outcome	2003

Article

Year

Multicenter phase II study of oral bexarotene for patients with metastatic breast cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Mar-15, Volume: 21, Issue:6

Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bexarotene; Breast Neoplasms; Disease Progression; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Estrogen Receptor Modulators; Female; Humans; Middle Aged; Receptors, Estrogen; Receptors, Progesterone; Survival Analysis; Tamoxifen; Tetrahydronaphthalenes; Thyroid Hormones; Toremifene; Treatment Outcome

2003

Other Studies

12 other study(ies) available for bexarotene and Breast Cancer

Article	Year
Src is a novel potential off-target of RXR agonists, 9-cis-UAB30 and Targretin, in human breast cancer cells. Molecular carcinogenesis, 2015, Volume: 54, Issue:12 Topics: Bexarotene; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Fatty Acids, Unsaturated; Female; Humans; Matrix Metalloproteinase 9; MCF-7 Cells; Naphthalenes; Neoplasm Invasiveness; Oncogene Protein pp60(v-src); Proto-Oncogene Proteins c-akt; Retinoid X Receptors; Ribosomal Protein S6 Kinases, 70-kDa; Tetrahydronaphthalenes	2015
Dual targeting of retinoid X receptor and histone deacetylase with DW22 as a novel antitumor approach. Oncotarget, 2015, Volume: 6, Issue:12 Topics: Aged; Animals; Antineoplastic Agents; Bexarotene; Breast Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cyclin-Dependent Kinase Inhibitor p21; Drug Screening Assays, Antitumor; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase 1; Histones; HL-60 Cells; Human Umbilical Vein Endothelial Cells; Humans; Hydroxamic Acids; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, SCID; Middle Aged; Neoplasm Invasiveness; Neoplasm Transplantation; Neovascularization, Pathologic; Retinoid X Receptor alpha; RNA, Small Interfering; Tetrahydronaphthalenes; Up-Regulation; Vascular Endothelial Growth Factor A	2015
Identification of biomarkers regulated by rexinoids (LGD1069, LG100268 and Ro25-7386) in human breast cells using Affymetrix microarray. Molecular medicine reports, 2015, Volume: 12, Issue:1 Topics: Anticarcinogenic Agents; Bexarotene; Biomarkers, Tumor; Breast; Breast Neoplasms; Cell Proliferation; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Microarray Analysis; Neoplasm Proteins; Nicotinic Acids; Retinoid X Receptors; Tetrahydronaphthalenes	2015
Guggulsterone and bexarotene induce secretion of exosome-associated breast cancer resistance protein and reduce doxorubicin resistance in MDA-MB-231 cells. International journal of cancer, 2015, Oct-01, Volume: 137, Issue:7 Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Bexarotene; Breast Neoplasms; Cell Death; Cell Line, Tumor; Ceramides; Down-Regulation; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Exosomes; Humans; Neoplasm Proteins; Pregnenediones; Tetrahydronaphthalenes	2015
Rexinoids may be ready for prime time in prevention, but challenges remain. Journal of the National Cancer Institute, 2004, Dec-15, Volume: 96, Issue:24 Topics: Animals; Anticarcinogenic Agents; Bexarotene; Breast Neoplasms; Clinical Trials as Topic; Disease Models, Animal; Female; Humans; Nicotinic Acids; Piperidines; Retinoid X Receptors; Tetrahydronaphthalenes; Thiophenes	2004
The retinoid X receptor-selective retinoid, LGD1069, down-regulates cyclooxygenase-2 expression in human breast cells through transcription factor crosstalk: implications for molecular-based chemoprevention. Cancer research, 2005, Apr-15, Volume: 65, Issue:8 Topics: Animals; Anticarcinogenic Agents; Bexarotene; Breast; Breast Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Down-Regulation; E1A-Associated p300 Protein; Female; Humans; Mammary Neoplasms, Experimental; Membrane Proteins; Mice; Nuclear Proteins; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Retinoid X Receptors; Substrate Specificity; Tetrahydronaphthalenes; Trans-Activators; Transcription Factor AP-1; Transcriptional Activation; Transfection	2005
The selective retinoid X receptor agonist bexarotene (LGD1069, Targretin) prevents and overcomes multidrug resistance in advanced breast carcinoma. Molecular cancer therapeutics, 2005, Volume: 4, Issue:5 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bexarotene; Breast Neoplasms; Cisplatin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Endothelial Cells; Female; Humans; Mice; Mice, Nude; Neoplasm Invasiveness; Neovascularization, Pathologic; Paclitaxel; Retinoid X Receptors; Survival Rate; Tetrahydronaphthalenes; Umbilical Veins	2005
Identification of biomarkers modulated by the rexinoid LGD1069 (bexarotene) in human breast cells using oligonucleotide arrays. Cancer research, 2006, Dec-15, Volume: 66, Issue:24 Topics: Animals; Anticarcinogenic Agents; Bexarotene; Biomarkers; Breast; Breast Neoplasms; Female; Gene Expression Regulation; Humans; Mice; Mice, Transgenic; Oligonucleotide Array Sequence Analysis; Retinoids; Tetrahydronaphthalenes; Transplantation, Heterologous	2006
Retinoic acid receptor alpha expression correlates with retinoid-induced growth inhibition of human breast cancer cells regardless of estrogen receptor status. Cancer research, 1997, Jul-01, Volume: 57, Issue:13 Topics: Alitretinoin; Aminobenzoates; Antineoplastic Agents; Benzoates; Bexarotene; Breast Neoplasms; Cell Division; Chromans; Female; Humans; Nicotinic Acids; Nuclear Proteins; Receptors, Estrogen; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; Retinoids; Tetrahydronaphthalenes; Transcription Factors; Tretinoin; Tumor Cells, Cultured	1997
Growth inhibition of human in vitro and mouse in vitro and in vivo mammary tumor models by retinoids in comparison with tamoxifen and the RU-486 anti-progestagen. Breast cancer research and treatment, 1998, Volume: 51, Issue:1 Topics: Alitretinoin; Animals; Anticarcinogenic Agents; Apoptosis; Benzoates; Bexarotene; Breast Neoplasms; Cell Division; Disease Models, Animal; Female; Fenretinide; Hormone Antagonists; Humans; Mammary Neoplasms, Animal; Mice; Mice, Inbred C57BL; Mifepristone; Retinoids; Tamoxifen; Tetrahydronaphthalenes; Tretinoin; Tumor Cells, Cultured	1998
Drug approval summaries: arsenic trioxide, tamoxifen citrate, anastrazole, paclitaxel, bexarotene. The oncologist, 2001, Volume: 6, Issue:1 Topics: Anastrozole; Anticarcinogenic Agents; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Arsenic Trioxide; Arsenicals; Bexarotene; Breast Neoplasms; Drug Approval; Female; Humans; Leukemia, Promyelocytic, Acute; Lymphoma, T-Cell, Cutaneous; Nitriles; Oxides; Paclitaxel; Tamoxifen; Tetrahydronaphthalenes; Triazoles; United States; United States Food and Drug Administration	2001
Suppression of mammary tumorigenesis in transgenic mice by the RXR-selective retinoid, LGD1069. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2002, Volume: 11, Issue:5 Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents; Benzoates; Bexarotene; Biomarkers, Tumor; Breast Neoplasms; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Growth Inhibitors; Histones; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; Sensitivity and Specificity; Tetrahydronaphthalenes; Time Factors; Transcription Factors; Treatment Outcome	2002