Page last updated: 2024-08-25

bexarotene and Benign Neoplasms

bexarotene has been researched along with Benign Neoplasms in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (13.64)18.2507
2000's6 (27.27)29.6817
2010's8 (36.36)24.3611
2020's5 (22.73)2.80

Authors

AuthorsStudies
Atigadda, VR; Boerma, LJ; Brouillette, WJ; Christov, K; Desphande, A; Grubbs, CJ; Lobo-Ruppert, S; Moeinpour, FL; Muccio, DD; Smith, CD; Vines, KK; Xia, G1
Brown, PH; Contreras, A; Dimond, E; Heckman-Stoddard, BM; Hernandez, M; Khan, SA; Lee, JJ; Liu, DD; Mays, C; Muzzio, M; Patel, AB; Perloff, M; Sepeda, V; Thomas, PS; Vornik, LA; Weber, D1
Al-Madhagi, H; Alasmari, AF; Alasmari, F; Alharbi, M; Khan, M; Khan, MQ; Shahab, M; Wadood, A; Zeb, A; Zheng, G1
Chowdhury, AS; Hung, PY; Leal, AS; Liby, KT1
Ding, Y; Dvornikov, AV; Ekker, SC; Herrmann, J; Hsiai, TK; Kim, M; Lin, X; Lowerison, M; Ma, X; Norton, N; Qiu, Q; Wang, Y; Wang, Z; Xu, X; Yu, Y; Zhang, H; Zhu, P1
Leal, AS; Liby, KT; Moerland, JA; Reich, LA; Zhang, D1
Chen, Y; Cheng, F; Li, G; Shen, D; Wu, Y; Xia, L; Yu, X1
Appetecchia, M; Baldelli, R; Barnabei, A; Corsello, SM; Paragliola, R; Torino, F1
Cao, X; Guo, Y; Luan, Y; Qi, L; Zhang, P1
Baggstrom, MQ; Fracasso, PM; Govindan, R; Read, WL1
Collins, B; Hwang, J; Malik, SM; Marshall, J; Pishvaian, M; Ramzi, P1
Hamnvik, OP; Larsen, PR; Marqusee, E1
Chang, WC; Clapper, ML; Fischer, SM; Grubbs, CJ; Juliana, MM; Lubet, RA; McCormick, DL; Pereira, MA; Steele, VE1
Baso, JC; Bhogal, JS; Browder, DO; Furmick, JK; Gray, GM; Groy, TL; Huynh, CC; Jurutka, PW; Kaneko, I; Kwon, JS; Lemming, B; Marcus, LM; Marshall, PA; Montano, LA; Prentice, JL; Quezada, A; Reyes, NM; Saini, P; Tsosie, DG; van der Vaart, A; Wagner, CE; Walsh, AN; Yang, J1
Farol, LT; Hymes, KB1
Mei, JH; Wang, MW1
Baggstrom, MQ; Fracasso, PM; Govindan, R; Read, W; Suresh, R; Wildi, JD1
Benedetti, FM; Crisp, M; Heyman, R; Kris, MG; Loewen, GR; Miller, VA; Pfister, DG; Rigas, JR; Straus, D; Truglia, JA; Verret, AL; Warrell, RP1
Dahut, W; Geiser, R; Gill, GM; Hawkins, MJ; Jaunakais, D; Loewen, G; Marshall, JL; Ness, E; Rizvi, NA; Truglia, JA; Ulm, EH1
Hurst, RE1
Anderson, B; Smith, MA1

Reviews

9 review(s) available for bexarotene and Benign Neoplasms

ArticleYear
Retinoid X Receptor agonists as selective modulators of the immune system for the treatment of cancer.
    Pharmacology & therapeutics, 2023, Volume: 252

    Topics: Bexarotene; Humans; Immune System; Inflammation; Neoplasms; Retinoid X Receptors; Tumor Microenvironment

2023
Potential therapeutic uses of rexinoids.
    Advances in pharmacology (San Diego, Calif.), 2021, Volume: 91

    Topics: Bexarotene; Humans; Neoplasms; Receptors, Cytoplasmic and Nuclear; Retinoid X Receptors; Tumor Microenvironment

2021
Emerging roles of bexarotene in the prevention, treatment and anti-drug resistance of cancers.
    Expert review of anticancer therapy, 2018, Volume: 18, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Bexarotene; Cell Differentiation; Cell Proliferation; Drug Resistance, Neoplasm; Humans; Neoplasms; Neovascularization, Pathologic

2018
Thyroid dysfunction as an unintended side effect of anticancer drugs.
    Thyroid : official journal of the American Thyroid Association, 2013, Volume: 23, Issue:11

    Topics: Alemtuzumab; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bexarotene; Diphtheria Toxin; Humans; Hypothyroidism; Interferon-alpha; Interleukin-2; Lenalidomide; Neoplasms; Recombinant Fusion Proteins; Tetrahydronaphthalenes; Thalidomide; Thyroid Diseases; Thyroid Gland; Thyroid Hormones; Thyroxine

2013
Preventive and Therapeutic Effects of the Retinoid X Receptor Agonist Bexarotene on Tumors.
    Current drug metabolism, 2016, Volume: 17, Issue:2

    Topics: Animals; Antineoplastic Agents; Bexarotene; Humans; Neoplasms; Retinoid X Receptors; Tetrahydronaphthalenes

2016
Thyroid dysfunction from antineoplastic agents.
    Journal of the National Cancer Institute, 2011, Nov-02, Volume: 103, Issue:21

    Topics: Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Anticarcinogenic Agents; Antineoplastic Agents; Bexarotene; Diphtheria Toxin; Humans; Hyperthyroidism; Hypopituitarism; Hypothyroidism; Interferon-alpha; Interleukin-2; Iodine Radioisotopes; Ipilimumab; Lenalidomide; Molecular Targeted Therapy; Neoplasms; Protein-Tyrosine Kinases; Quality of Life; Radioimmunotherapy; Recombinant Fusion Proteins; Recombinant Proteins; Tetrahydronaphthalenes; Thalidomide; Thyroid Function Tests; Thyroid Gland; Thyroid Hormones; Thyroiditis, Autoimmune

2011
Bexarotene: a clinical review.
    Expert review of anticancer therapy, 2004, Volume: 4, Issue:2

    Topics: Anticarcinogenic Agents; Bexarotene; Breast Neoplasms; Clinical Trials as Topic; Humans; Lung Neoplasms; Lymphoma, T-Cell, Cutaneous; Neoplasms; Skin Neoplasms; Tetrahydronaphthalenes

2004
[Advances in studies on selective RXR ligands].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2005, Volume: 40, Issue:4

    Topics: Alitretinoin; Animals; Antineoplastic Agents; Bexarotene; Humans; Ligands; Neoplasms; Retinoid X Receptors; Retinoids; Structure-Activity Relationship; Tetrahydronaphthalenes; Tretinoin

2005
Bexarotene ligand pharmaceuticals.
    Current opinion in investigational drugs (London, England : 2000), 2000, Volume: 1, Issue:4

    Topics: Animals; Anticarcinogenic Agents; Bexarotene; Clinical Trials as Topic; Contraindications; Drugs, Investigational; Humans; Neoplasms; Receptors, Retinoic Acid; Retinoid X Receptors; Structure-Activity Relationship; Tetrahydronaphthalenes; Transcription Factors

2000

Trials

6 trial(s) available for bexarotene and Benign Neoplasms

ArticleYear
Phase I Dose Escalation Study of Topical Bexarotene in Women at High Risk for Breast Cancer.
    Cancer prevention research (Philadelphia, Pa.), 2023, 01-04, Volume: 16, Issue:1

    Topics: Administration, Topical; Antineoplastic Agents; Bexarotene; Female; Humans; Neoplasms

2023
A phase I study of bexarotene and rosiglitazone in patients with refractory cancers.
    Chemotherapy, 2008, Volume: 54, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bexarotene; Female; Humans; Male; Middle Aged; Neoplasms; Rosiglitazone; Tetrahydronaphthalenes; Thiazolidinediones

2008
A phase I trial of bexarotene in combination with docetaxel in patients with advanced solid tumors.
    Clinical lung cancer, 2011, Volume: 12, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bexarotene; Docetaxel; Female; Follow-Up Studies; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Neoplasms; Survival Rate; Taxoids; Tetrahydronaphthalenes; Treatment Outcome; Young Adult

2011
A phase I study of docetaxel and bexarotene.
    Chemotherapy, 2008, Volume: 54, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bexarotene; Docetaxel; Drug Administration Schedule; Fatigue; Female; Humans; Male; Middle Aged; Nausea; Neoplasms; Taxoids; Tetrahydronaphthalenes

2008
Initial clinical trial of a selective retinoid X receptor ligand, LGD1069.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anticarcinogenic Agents; Area Under Curve; Bexarotene; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Neoplasms; Tetrahydronaphthalenes

1997
A Phase I study of LGD1069 in adults with advanced cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anticarcinogenic Agents; Bexarotene; Female; Headache; Humans; Leukopenia; Male; Middle Aged; Neoplasm Staging; Neoplasms; Tetrahydronaphthalenes; Treatment Outcome

1999

Other Studies

7 other study(ies) available for bexarotene and Benign Neoplasms

ArticleYear
Methyl-substituted conformationally constrained rexinoid agonists for the retinoid X receptors demonstrate improved efficacy for cancer therapy and prevention.
    Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1

    Topics: Humans; Kruppel-Like Factor 4; Ligands; Molecular Conformation; Neoplasms; Retinoid X Receptors; Retinoids

2014
Structure based virtual screening and molecular simulation study of FDA-approved drugs to inhibit human HDAC6 and VISTA as dual cancer immunotherapy.
    Scientific reports, 2023, 09-02, Volume: 13, Issue:1

    Topics: Bexarotene; Blood Group Antigens; Early Detection of Cancer; Histone Deacetylase 6; Humans; Immunotherapy; Neoplasms; Oxymorphone

2023
Retinoid X receptor alpha is a spatiotemporally predominant therapeutic target for anthracycline-induced cardiotoxicity.
    Science advances, 2020, Volume: 6, Issue:5

    Topics: Animals; Bexarotene; Cardiotonic Agents; Cardiotoxicity; Disease Models, Animal; Endothelial Cells; Heart; Humans; Isotretinoin; Myocardium; Neoplasms; Pericardium; Retinoid X Receptor alpha; Zebrafish; Zonula Occludens-1 Protein

2020
Chemopreventive efficacy of Targretin in rodent models of urinary bladder, colon/intestine, head and neck and mammary cancers.
    Oncology reports, 2012, Volume: 27, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Bexarotene; Celecoxib; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Female; Head and Neck Neoplasms; Intestinal Neoplasms; Male; Mammary Neoplasms, Animal; Mice; Mice, Knockout; Neoplasms; Pyrazoles; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Sulfonamides; Tetrahydronaphthalenes; Urinary Bladder Neoplasms

2012
Modeling, synthesis and biological evaluation of potential retinoid X receptor-selective agonists: novel halogenated analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene).
    ChemMedChem, 2012, Volume: 7, Issue:9

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Bexarotene; Cell Line, Tumor; Halogenation; Humans; Lymphoma, T-Cell, Cutaneous; Molecular Docking Simulation; Neoplasms; Protein Multimerization; Retinoid X Receptors; Tetrahydronaphthalenes

2012
New genetic mechanism associated with thyroid-related diseases.
    Oncology (Williston Park, N.Y.), 1999, Volume: 13, Issue:7

    Topics: Anticarcinogenic Agents; Bexarotene; Female; Humans; Hypothyroidism; Incidence; Male; Neoplasms; Tetrahydronaphthalenes; Thyroid Gland; Thyroid Hormones; Thyrotropin; United States

1999
Where to next with retinoids for cancer therapy?
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:10

    Topics: Alitretinoin; Antineoplastic Agents; Bexarotene; Humans; Isotretinoin; Neoplasms; Retinoids; Tetrahydronaphthalenes; Tretinoin

2001