Page last updated: 2024-10-23

bevantolol and Huntington Disease

bevantolol has been researched along with Huntington Disease in 1 studies

bevantolol: structure given in first source
bevantolol : A propanolamine that is 3-aminopropane-1,2-diol in which the hydrogen of the primary hydroxy group is substituted by 3-methylphenyl and one of the hydrogens attached to the nitrogen is substituted by 2-(3,4-dimethoxyphenyl)ethyl. A beta1 adrenoceptor antagonist, it has been shown to be as effective as other beta-blockers for the treatment of angina pectoris and hypertension.

Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Gamez, J2
Calopa, M2
Muñoz, E2
Ferré, A2
Huertas, O2
McAllister, K2
Reig, N2
Scart-Grès, C2
Insa, R2
Kulisevsky, J2

Trials

1 trial available for bevantolol and Huntington Disease

ArticleYear
A proof-of-concept study with SOM3355 (bevantolol hydrochloride) for reducing chorea in Huntington's disease.
    British journal of clinical pharmacology, 2023, Volume: 89, Issue:5

    Topics: Chorea; Double-Blind Method; Humans; Huntington Disease; Tetrabenazine; Treatment Outcome; Vesicular

2023
A proof-of-concept study with SOM3355 (bevantolol hydrochloride) for reducing chorea in Huntington's disease.
    British journal of clinical pharmacology, 2023, Volume: 89, Issue:5

    Topics: Chorea; Double-Blind Method; Humans; Huntington Disease; Tetrabenazine; Treatment Outcome; Vesicular

2023
A proof-of-concept study with SOM3355 (bevantolol hydrochloride) for reducing chorea in Huntington's disease.
    British journal of clinical pharmacology, 2023, Volume: 89, Issue:5

    Topics: Chorea; Double-Blind Method; Humans; Huntington Disease; Tetrabenazine; Treatment Outcome; Vesicular

2023
A proof-of-concept study with SOM3355 (bevantolol hydrochloride) for reducing chorea in Huntington's disease.
    British journal of clinical pharmacology, 2023, Volume: 89, Issue:5

    Topics: Chorea; Double-Blind Method; Humans; Huntington Disease; Tetrabenazine; Treatment Outcome; Vesicular

2023