betulinic acid has been researched along with Innate Inflammatory Response in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (5.88) | 29.6817 |
| 2010's | 16 (47.06) | 24.3611 |
| 2020's | 16 (47.06) | 2.80 |
| Authors | Studies |
|---|---|
| Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J | 1 |
| Alakurtti, S; Haavikko, R; Hämäläinen, M; Laavola, M; Leppänen, T; Moilanen, E; Moreira, VM; Nieminen, R; Yli-Kauhaluoma, J | 1 |
| Kishore, N; Kumar, P; Shanker, K; Verma, AK | 1 |
| Adaramoye, OA; Adeleke, GE | 1 |
| Cunha, NL; Cunha, WR; de A E Silva, ML; de Freitas, KS; de Melo, MRS; do Nascimento, S; Fernandes, FS; Ferreira, NH; Ribeiro, AB; Tavares, DC | 1 |
| Chen, Y; Huang, L; Huang, Y; Kong, L; Ma, C; Ou, Z; Wen, L; Wu, J; Yi, J; Yuan, Z; Zhao, H; Zhu, L | 1 |
| Huang, Y; Kong, L; Li, R; Luo, C; Ma, C; Wu, J; Yi, J; Yuan, Z; Zhu, L; Zhu, Z | 1 |
| Hu, P; Zhu, C | 1 |
| Ge, X; Guo, S; Jiao, T; Li, C; Liu, Y; Nan, F; Wang, K; Wang, Y; Xie, C; Xie, X; Yin, J; Zhang, C | 1 |
| Huang, C; Huang, Y; Jiang, W; Kong, L; Luo, C; Ma, C; Yang, W; Yi, J; Zhu, L | 1 |
| De Hoz-Rivera, M; Del Pozo, A; Martínez-Orgado, J; Martínez-Vega, M; Muñoz, E; Prados, ME; Romero, A; Silva, L; Villa, M | 1 |
| Alruhaimi, RS | 1 |
| Chen, Y; Li, J; Wang, J; Wang, N; Wu, J; Wu, Y; Yang, C; Yang, M; Yi, J; Yuan, Z | 1 |
| Adepoju, FO; Duru, KC; Kovaleva, EG; Li, E; Tsurkan, MV | 1 |
| Pan, J; Song, Q; Wang, Y; Zhang, Y | 1 |
| Appendino, G; Calzado, MA; Collado, JA; García-Martín, A; Minassi, A; Muñoz, E; Palomares, B; Prados, ME; Unciti-Broceta, JD | 1 |
| Baev, DS; Frolova, TS; Khlebnicova, TS; Lakhvich, FA; Piven, YA; Sorokina, IV; Tolstikova, TG | 1 |
| Huang, C; Kong, L; Li, R; Luo, C; Wen, L; Wu, J; Yi, J; Yuan, Z; Zhu, L | 1 |
| Ajibesin, K; Akpan, O; Archibong, B; De Leo, M; Eseyin, O; Essien, E; Etukudo, E; Flamini, G; Thomas, P; Udoh, A | 1 |
| A, H; Mathew, LE; Rajagopal, V | 1 |
| Máñez, S; Ríos, JL | 1 |
| Akhtar, M; Deshmukh, R; Kaundal, M | 1 |
| Badavi, M; Farbood, Y; Ghadiri, A; Ghasemi Dehcheshmeh, M; Mansouri, E; Navabi, SP; Sarkaki, A | 1 |
| Chen, F; Jiang, LS; Lv, CC; Shu, SJ; Xia, ML | 1 |
| Chen, J; Deng, L; Gong, Z; Han, L; Li, N; Li, X; Lin, C; Liu, D; Liu, Q; Ma, Q; Pan, D; Wang, Q; Wei, Z; Wu, M | 1 |
| Barbosa-Filho, JM; Barreto, BC; Caria, ACI; Macambira, SG; Meira, CS; Moreira, DRM; Nonaka, CKV; Orge, ID; Santo, RFDE; Santos, ES; Silva, DN; Soares, MBP; Vasconcelos, JF | 1 |
| Oridupa, OA; Oyebanji, BO; Saba, AB | 1 |
| Balaganur, V; Begum, J; Bhat, RA; Kandasamy, K; Kumar, D; Lingaraju, MC; Pathak, NN; Ram, M; Ramachandra, HD; Singh, V; Tandan, SK | 1 |
| DeMorrow, S; Dusio, G; Frampton, G; Grant, S; McMillin, M; Newell-Rogers, K; Shin, H; Smith, J; Tobin, R | 1 |
| Aimin, C; Huaining, L; Jingbo, W; Qi, W; Xin, L | 1 |
| Alaoui, K; Asongalem, AE; Azebaze, AG; Cherrah, Y; Dimo, T; Dongmo, AB; Kamtchouing, P; Nguemfo, EL | 1 |
| Helen, A; Luxmi, VR; Viji, V | 1 |
| Chen, CH; Huang, L; Hung, HY; Kim, SY; Lee, KH; Qian, K | 1 |
| Dinkova-Kostova, AT; Gribble, GW; Honda, T; Liby, K; Risingsong, R; Royce, DB; Sporn, MB; Stephenson, KK; Suh, N; Sundararajan, C; Talalay, P; Williams, CR | 1 |
3 review(s) available for betulinic acid and Innate Inflammatory Response
| Article | Year |
|---|---|
Human disorders associated with inflammation and the evolving role of natural products to overcome.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biological Products; Cardiovascular Diseases; Humans; Inflammation; Neoplasms; Skin Diseases | 2019 |
Pharmacological Potential of Betulin as a Multitarget Compound.
Topics: Betulinic Acid; Cytokines; Humans; Inflammation; NF-kappa B; Triterpenes | 2023 |
New Pharmacological Opportunities for Betulinic Acid.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Antiviral Agents; Betulinic Acid; Cytotoxins; Diabetes Mellitus, Type 2; Dyslipidemias; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Inflammation; Metabolic Syndrome; Pentacyclic Triterpenes; Triterpenes | 2018 |
31 other study(ies) available for betulinic acid and Innate Inflammatory Response
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature | 2010 |
Betulin Derivatives Effectively Suppress Inflammation in Vitro and in Vivo.
Topics: Animals; Anti-Inflammatory Agents; Betula; Betulinic Acid; Carrageenan; Chemokine CCL2; Cyclooxygenase 2; Cytokines; Dinoprostone; Inflammation; Interleukin-6; Lipopolysaccharides; Macrophages; Male; Mice; Molecular Structure; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Pentacyclic Triterpenes; Triterpenes | 2016 |
Betulinic acid abates N-nitrosodimethylamine-induced changes in lipid metabolism, oxidative stress, and inflammation in the liver and kidney of Wistar rats.
Topics: Animals; Betulinic Acid; Dimethylnitrosamine; Inflammation; Kidney; Lipid Metabolism; Liver; Male; Oxidative Stress; Pentacyclic Triterpenes; Rats; Rats, Wistar | 2021 |
Betulinic acid exerts antigenotoxic and anticarcinogenic activities via inhibition of COX-2 and PCNA in rodents.
Topics: Animals; Anticarcinogenic Agents; Antimutagenic Agents; Betulinic Acid; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Doxorubicin; Inflammation; Male; Mice; Pentacyclic Triterpenes; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Signal Transduction | 2021 |
Betulinic acid protects against renal damage by attenuation of oxidative stress and inflammation via Nrf2 signaling pathway in T-2 toxin-induced mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Betulinic Acid; Gene Expression Regulation; Inflammation; Kidney Diseases; Male; Mice; NF-E2-Related Factor 2; Oxidative Stress; Pentacyclic Triterpenes; Random Allocation; Signal Transduction; T-2 Toxin | 2021 |
Betulinic acid attenuates cognitive dysfunction, oxidative stress, and inflammation in a model of T-2 toxin-induced brain damage.
Topics: Animals; Antioxidants; Betulinic Acid; Brain; Cognitive Dysfunction; Cytokines; Glutathione; Inflammation; Mice; Oxidative Stress; Pentacyclic Triterpenes; RNA, Messenger; T-2 Toxin | 2022 |
Betulinic Acid Exerts Anti-inflammatory Activity in Human Periodontal Ligament Cells Stimulated with Lipopolysaccharide and/or High Glucose.
Topics: Anti-Inflammatory Agents; Betulinic Acid; Cyclooxygenase 2; Dinoprostone; Glucose; Humans; Inflammation; Lipopolysaccharides; NF-kappa B; Nitrites; Periodontal Ligament | 2023 |
Discovery of Betulinic Acid Derivatives as Potent Intestinal Farnesoid X Receptor Antagonists to Ameliorate Nonalcoholic Steatohepatitis.
Topics: Animals; Betulinic Acid; Bile Acids and Salts; Ceramides; Fibrosis; Glucose; Inflammasomes; Inflammation; Islet Amyloid Polypeptide; Liver; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Pentacyclic Triterpenes; Receptors, Cytoplasmic and Nuclear | 2022 |
Inhibition of the NF-κB pathway and ERK-mediated mitochondrial apoptotic pathway takes part in the mitigative effect of betulinic acid on inflammation and oxidative stress in cyclophosphamide-triggered renal damage of mice.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Betulinic Acid; Cyclophosphamide; Cytokines; Extracellular Signal-Regulated MAP Kinases; Inflammation; Kidney; Mice; NF-kappa B; Oxidative Stress; RNA, Messenger | 2022 |
Neuroprotective Effects of Betulinic Acid Hydroxamate in Intraventricular Hemorrhage-Induced Brain Damage in Immature Rats.
Topics: Animals; Betulinic Acid; Brain; Cerebral Hemorrhage; Humans; Infant, Newborn; Infant, Premature; Inflammation; Neuroprotective Agents; Rats; Rats, Wistar | 2022 |
Betulinic acid protects against cardiotoxicity of the organophosphorus pesticide chlorpyrifos by suppressing oxidative stress, inflammation, and apoptosis in rats.
Topics: Animals; Antioxidants; Apoptosis; Betulinic Acid; Cardiotoxicity; Chlorpyrifos; Humans; Inflammation; Interleukin-6; NF-E2-Related Factor 2; NF-kappa B; Organophosphorus Compounds; Oxidative Stress; Pesticides; Rats; Tumor Necrosis Factor-alpha | 2023 |
Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice.
Topics: Animals; Apoptosis; Betulinic Acid; Chemical and Drug Induced Liver Injury, Chronic; Endoplasmic Reticulum Stress; Humans; Inflammation; Kelch-Like ECH-Associated Protein 1; Mice; NF-E2-Related Factor 2; Oxidative Stress; Signal Transduction; Zearalenone | 2023 |
The role of Vav3 expression for inflammation and cell death during experimental myocardial infarction.
Topics: Animals; Apoptosis; Betulinic Acid; Cell Death; Hydrogen Peroxide; Inflammation; Myocardial Infarction; NF-kappa B; Rats | 2023 |
Betulinic acid hydroxamate prevents colonic inflammation and fibrosis in murine models of inflammatory bowel disease.
Topics: Animals; Anti-Inflammatory Agents; Betulinic Acid; Caco-2 Cells; Colon; Dextran Sulfate; Fibrosis; Gastrointestinal Agents; Gene Expression; Humans; Hydroxamic Acids; Inflammation; Inflammatory Bowel Diseases; Intestinal Mucosa; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; NIH 3T3 Cells; Pentacyclic Triterpenes; Trinitrobenzenesulfonic Acid | 2021 |
Betulinic Acid-Azaprostanoid Hybrids: Synthesis and Pharmacological Evaluation as Anti-inflammatory Agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Betulinic Acid; Cytotoxicity Tests, Immunologic; Drug Design; Humans; Inflammation; Pentacyclic Triterpenes; Plant Extracts; Prostaglandins; Technology, Pharmaceutical; Triterpenes | 2020 |
Betulinic Acid Ameliorates the T-2 Toxin-Triggered Intestinal Impairment in Mice by Inhibiting Inflammation and Mucosal Barrier Dysfunction through the NF-κB Signaling Pathway.
Topics: Animals; Antioxidants; Betulinic Acid; Dose-Response Relationship, Drug; Inflammation; Inflammation Mediators; Intestinal Mucosa; Male; Mice; NF-kappa B; Oxidative Stress; Pentacyclic Triterpenes; Signal Transduction; T-2 Toxin | 2020 |
Isolation and characterization of anti-inflammatory and analgesic compounds from Uapaca staudtii Pax (Phyllanthaceae) stem bark.
Topics: Africa, Western; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Behavior, Animal; Betulinic Acid; Disease Models, Animal; Edema; Female; Free Radical Scavengers; Hydroxybenzoates; Inflammation; Male; Mice; Pain; Pentacyclic Triterpenes; Phenol; Phyllanthus; Plant Bark; Plant Extracts | 2021 |
Betulinic acid and fluvastatin exhibits synergistic effect on toll-like receptor-4 mediated anti-atherogenic mechanism in type II collagen induced arthritis.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Atherosclerosis; Betulinic Acid; C-Reactive Protein; Collagen Type II; Fatty Acids, Monounsaturated; Female; Fluvastatin; Indoles; Inflammation; Interferon-gamma; Interleukin-10; Interleukin-1beta; Leukocytes, Mononuclear; NF-kappa B; Pentacyclic Triterpenes; Rats; Rats, Sprague-Dawley; Toll-Like Receptor 4; Triterpenes; Tumor Necrosis Factor-alpha | 2017 |
Protective effect of betulinic acid against intracerebroventricular streptozotocin induced cognitive impairment and neuronal damage in rats: Possible neurotransmitters and neuroinflammatory mechanism.
Topics: Acetylcholinesterase; Animals; Betulinic Acid; Cognitive Dysfunction; Disease Models, Animal; Donepezil; Glutathione; Hippocampus; Indans; Inflammation; Injections, Intraventricular; Male; Maze Learning; Memory; Memory Disorders; Neuroprotective Agents; Neurotransmitter Agents; Oxidative Stress; Pentacyclic Triterpenes; Piperidines; Rats; Rats, Wistar; Streptozocin; Triterpenes | 2018 |
The protective effect of betulinic acid on microvascular responsivity and protein expression in alzheimer disease induced by cerebral micro-injection of beta-amyloid and streptozotocin.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Betulinic Acid; Brain-Derived Neurotrophic Factor; Inflammation; Microcirculation; Pentacyclic Triterpenes; Protective Agents; Proteins; Rats; Streptozocin; Triterpenes | 2018 |
Attenuation of Remifentanil-Induced Hyperalgesia by Betulinic Acid Associates with Inhibiting Oxidative Stress and Inflammation in Spinal Dorsal Horn.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Betulinic Acid; Drug Interactions; Ganglia, Spinal; Hyperalgesia; Inflammation; Interleukin-1beta; Male; Oxidative Stress; Pain, Postoperative; Pentacyclic Triterpenes; Random Allocation; Rats; Rats, Sprague-Dawley; Remifentanil; Spinal Cord Dorsal Horn; Superoxide Dismutase; Triterpenes; Tumor Necrosis Factor-alpha; Tyrosine | 2018 |
Betulinic acid inhibits the migration and invasion of fibroblast-like synoviocytes from patients with rheumatoid arthritis.
Topics: Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, Rheumatoid; Betulinic Acid; Cell Movement; Cells, Cultured; Cytokines; Disease Models, Animal; Female; Fibroblasts; Humans; Inflammation; Male; Mice; Mice, Inbred DBA; Middle Aged; NF-kappa B; Pentacyclic Triterpenes; Signal Transduction; Synoviocytes; Triterpenes | 2019 |
Betulinic Acid Derivative BA5, Attenuates Inflammation and Fibrosis in Experimental Chronic Chagas Disease Cardiomyopathy by Inducing IL-10 and M2 Polarization.
Topics: Animals; Anti-Inflammatory Agents; Betulinic Acid; Chagas Cardiomyopathy; Chronic Disease; Disease Models, Animal; Fibrosis; Inflammation; Interleukin-10; Macrophages; Mice; Pentacyclic Triterpenes; Triterpenes; Trypanosoma cruzi | 2019 |
Studies on the anti-inflammatory, analgesic and antipyrexic activities of betulinic acid derived from Tetracera potatoria.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Betulinic Acid; Carrageenan; Dilleniaceae; Female; Fever; Inflammation; Lung; Male; Mice; Mice, Inbred Strains; Pain; Pentacyclic Triterpenes; Phytotherapy; Plant Extracts; Pulmonary Edema; Random Allocation; Rats; Rats, Wistar; Triterpenes; Zymosan | 2014 |
Betulinic acid attenuates renal oxidative stress and inflammation in experimental model of murine polymicrobial sepsis.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Betulinic Acid; Coinfection; Disease Models, Animal; Inflammation; Male; Mice; Oxidative Stress; Pentacyclic Triterpenes; Sepsis; Triterpenes | 2015 |
TGR5 signaling reduces neuroinflammation during hepatic encephalopathy.
Topics: Animals; Betulinic Acid; Cells, Cultured; Hepatic Encephalopathy; Inflammation; Male; Mice; Mice, Inbred C57BL; Pentacyclic Triterpenes; Receptors, G-Protein-Coupled; Signal Transduction; Triterpenes | 2015 |
Betulinic acid inhibits IL-1β-induced inflammation by activating PPAR-γ in human osteoarthritis chondrocytes.
Topics: Aged; Betulinic Acid; Cell Survival; Cells, Cultured; Chondrocytes; Dinoprostone; Gene Expression Regulation; Humans; Inflammation; Interleukin-1beta; Matrix Metalloproteinases; Middle Aged; NF-kappa B; Nitric Oxide; Osteoarthritis; Pentacyclic Triterpenes; PPAR gamma; Triterpenes | 2015 |
Anti-oxidative and anti-inflammatory activities of some isolated constituents from the stem bark of Allanblackia monticola Staner L.C (Guttiferae).
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Betulinic Acid; Carrageenan; Clusiaceae; Disease Models, Animal; Female; Free Radical Scavengers; Inflammation; Inhibitory Concentration 50; Male; Pentacyclic Triterpenes; Plant Bark; Plant Extracts; Rats; Rats, Wistar; Triterpenes; Xanthones | 2009 |
Betulinic acid inhibits endotoxin-stimulated phosphorylation cascade and pro-inflammatory prostaglandin E(2) production in human peripheral blood mononuclear cells.
Topics: Animals; Betulinic Acid; Disease Models, Animal; Electrophoretic Mobility Shift Assay; Endotoxins; Humans; Inflammation; Leukocytes, Mononuclear; Male; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Pentacyclic Triterpenes; Peroxidase; Phosphorylation; Prostaglandins E; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Sepsis; Shock, Septic; Triterpenes | 2011 |
New betulinic acid derivatives as potent proteasome inhibitors.
Topics: Antineoplastic Agents; Betulinic Acid; Chymotrypsin; Cysteine Proteinase Inhibitors; Drug Design; Inflammation; Molecular Structure; Molecular Targeted Therapy; Neoplasms; Pentacyclic Triterpenes; Proteasome Inhibitors; Signal Transduction; Structure-Activity Relationship; Triterpenes | 2011 |
Novel semisynthetic analogues of betulinic acid with diverse cytoprotective, antiproliferative, and proapoptotic activities.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Betulinic Acid; Cell Line, Tumor; Cell Proliferation; Cytoprotection; Fibroblasts; Humans; Inflammation; Macrophages; Male; Mice; NAD(P)H Dehydrogenase (Quinone); Nitric Oxide; Pentacyclic Triterpenes; Triterpenes | 2007 |