betulinic acid has been researched along with Hepatocellular Carcinoma in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Carcache-Blanco, EJ; Fong, HH; Kang, YH; Kardono, LB; Kinghorn, AD; Park, EJ; Pezzuto, JM; Riswan, S; Su, BN | 1 |
| Chen, H; Feng, H; Huang, J; Huang, Y; Wang, M; Wei, Z; Wu, X; Xie, J; Yao, C | 1 |
| Bera, H; Bhadauria, AS; Gautam, AK; Kumar, D; Kumar, P; Kumar, U; Mahata, T; Maity, B; Saha, S; Singh, AK | 1 |
| Chen, H; Li, W; Lu, Y; Tao, R; Wang, C; Zhang, C; Zhou, H | 1 |
| Keshari, AK; Kumar, D; Kumar, P; Maiti, S; Maity, B; Prakash, A; Rai, A; Raj, V; Saha, S; Singh, AK | 1 |
| Bai, G; Huang, Y; Li, D; Li, Q; Liu, M; Shi, L; Wang, W; Wang, Y; Yang, T; Zhang, Y | 1 |
| Chen, C; Chen, L; Chen, M; Chen, W; Chen, Z; Fu, D; Hu, N; Lan, P; Lei, Y; Li, Y; Liu, M; Wang, C; Yao, N; Ye, W; Zhang, D | 1 |
| Chen, L; Liu, JH; Tang, J; Zhu, ZF | 1 |
| Li, X; Liu, W; Qiu, B; Yang, J; Zhang, H | 1 |
| Eichenmüller, M; Kappler, R; von Schweinitz, D | 1 |
| Chang, Q; Pan, R; Si, J; Tian, Z; Wu, E; Xiao, P | 1 |
11 other study(ies) available for betulinic acid and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Constituents of the stem bark of Pongamia pinnata with the potential to induce quinone reductase.
Topics: Animals; Anticarcinogenic Agents; Carcinoma, Hepatocellular; Enzyme Induction; Flavonoids; Indonesia; Mice; Millettia; Molecular Structure; NAD(P)H Dehydrogenase (Quinone); Nuclear Magnetic Resonance, Biomolecular; Plant Bark; Plant Stems; Plants, Medicinal; Stereoisomerism; Tumor Cells, Cultured | 2003 |
Targeting Effect of Betulinic Acid Liposome Modified by Hyaluronic Acid on Hepatoma Cells In Vitro.
Topics: Antineoplastic Agents; Betulinic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Hyaluronan Receptors; Hyaluronic Acid; Liposomes; Pentacyclic Triterpenes; Polymers; rho-Associated Kinases | 2022 |
Mechanistic exploration of the activities of poly(lactic-
Topics: Animals; Antineoplastic Agents; Apoptosis; Betulinic Acid; Carcinoma, Hepatocellular; Liver Neoplasms; Nanoparticles; Pentacyclic Triterpenes; Polylactic Acid-Polyglycolic Acid Copolymer; Proto-Oncogene Proteins c-bcl-2; Rats | 2022 |
Characterization and Cytotoxicity of Polyprenol Lipid and Vitamin E-TPGS Hybrid Nanoparticles for Betulinic Acid and Low-Substituted Hydroxyl Fullerenol in MHCC97H and L02 Cells.
Topics: Antineoplastic Agents; Betulinic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Delivery Systems; Drug Liberation; Fullerenes; Humans; Lipids; Liver Neoplasms; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Pentacyclic Triterpenes; Polyprenols; Triterpenes; Vitamin E | 2020 |
Poly(lactic-
Topics: Administration, Oral; Animals; Antineoplastic Agents; Apoptosis; Betulinic Acid; Carcinoma, Hepatocellular; Cell Proliferation; Chromatography, High Pressure Liquid; Drug Carriers; Drug Liberation; Half-Life; Hep G2 Cells; Humans; Inflammation Mediators; Kinetics; Lactic Acid; Liver; Liver Neoplasms; Male; Nanoparticles; Oxidative Stress; Particle Size; Pentacyclic Triterpenes; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Static Electricity; Triterpenes | 2018 |
Betulinic acid induces apoptosis and suppresses metastasis in hepatocellular carcinoma cell lines in vitro and in vivo.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Betulinic Acid; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID; Pentacyclic Triterpenes; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Triterpenes | 2019 |
Inhibition of PINK1/Parkin-dependent mitophagy sensitizes multidrug-resistant cancer cells to B5G1, a new betulinic acid analog.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagosomes; Autophagy; Beclin-1; Betulinic Acid; Carcinoma, Hepatocellular; Cell Survival; Drug Resistance, Multiple; GTP Phosphohydrolases; Hep G2 Cells; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Mitochondrial Proteins; Mitophagy; Pentacyclic Triterpenes; Protein Kinases; Reactive Oxygen Species; Transplantation, Heterologous; Triterpenes; Ubiquitin-Protein Ligases; Ubiquitination | 2019 |
Design, synthesis, and anti-tumor activity of novel betulinic acid derivatives.
Topics: Antineoplastic Agents; Betulinic Acid; Carcinoma, Hepatocellular; Drug Design; Humans; Liver Neoplasms; Molecular Structure; Nitric Oxide; Pentacyclic Triterpenes; Triterpenes | 2014 |
p53-p66(shc)/miR-21-Sod2 signaling is critical for the inhibitory effect of betulinic acid on hepatocellular carcinoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Betulinic Acid; Carbon Tetrachloride; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Diethylnitrosamine; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Liver Neoplasms; Mice; MicroRNAs; Pentacyclic Triterpenes; Random Allocation; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Superoxide Dismutase; Triterpenes; Tumor Suppressor Protein p53 | 2015 |
Betulinic acid treatment promotes apoptosis in hepatoblastoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Betulinic Acid; Carcinoma, Hepatocellular; Caspase 3; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Hedgehog Proteins; Hep G2 Cells; Hepatoblastoma; Humans; Inhibitor of Apoptosis Proteins; Insulin-Like Growth Factor II; Liver Neoplasms; Microtubule-Associated Proteins; Patched Receptors; Patched-1 Receptor; Pentacyclic Triterpenes; Phosphatidylinositol 3-Kinases; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Receptors, Cell Surface; Signal Transduction; Survivin; Transcription Factors; Triterpenes; Zinc Finger Protein GLI1 | 2009 |
Cimicifuga foetida extract inhibits proliferation of hepatocellular cells via induction of cell cycle arrest and apoptosis.
Topics: Animals; Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Betulinic Acid; Carcinoma, Hepatocellular; Cell Cycle; Cell Proliferation; Cells, Cultured; Cimicifuga; Dose-Response Relationship, Drug; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Hepatocytes; Humans; Male; Mice; Mice, Inbred ICR; Neoplasm Transplantation; Pentacyclic Triterpenes; Plant Extracts; Triterpenes; Xenograft Model Antitumor Assays | 2007 |