Compounds > betulinic acid

betulinic acid and Granulocytic Leukemia, Chronic

betulinic acid has been researched along with Granulocytic Leukemia, Chronic in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Fang, Q; Lu, T; Ma, D; Wang, J; Wei, D; Xiong, J; Yu, K1
Buffon, A; da Silva, GNS; de Oliveira, CB; Gnoatto, SCB; Pilger, DA; Trivella, DBB; Vieira, BD; Waechter, F; Willig, JB; Zimmer, AR1
Badrinath, Y; Joshi, DS; Mishra, KP; Narkar, AA; Raghuvar Gopal, DV1

Other Studies

3 other study(ies) available for betulinic acid and Granulocytic Leukemia, Chronic

ArticleYear
Betulinic acid restores imatinib sensitivity in BCR-ABL1 kinase-independent, imatinib-resistant chronic myeloid leukemia by increasing HDAC3 ubiquitination and degradation.
    Annals of the New York Academy of Sciences, 2020, Volume: 1467, Issue:1

    Topics: Adult; Apoptosis; Betulinic Acid; Bone Marrow Cells; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Histone Deacetylases; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Pentacyclic Triterpenes; Signal Transduction; Triterpenes; Ubiquitination; Young Adult

2020
Design, Synthesis and Biological Evaluation of Betulinic Acid Derivatives as New Antitumor Agents for Leukemia.
    Anti-cancer agents in medicinal chemistry, 2017, Volume: 17, Issue:13

    Topics: Antineoplastic Agents; Betulinic Acid; Drug Design; Drug Screening Assays, Antitumor; Humans; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Pentacyclic Triterpenes; Spectrum Analysis; Structure-Activity Relationship; Triterpenes

2017
Betulinic acid induces apoptosis in human chronic myelogenous leukemia (CML) cell line K-562 without altering the levels of Bcr-Abl.
    Toxicology letters, 2005, Mar-15, Volume: 155, Issue:3

    Topics: Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; Betulinic Acid; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Drug Evaluation, Preclinical; Electrophoresis, Agar Gel; Fluorescein-5-isothiocyanate; Fusion Proteins, bcr-abl; Gene Expression; Humans; Inhibitory Concentration 50; Intracellular Membranes; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Membrane Potentials; Mitochondria; Pentacyclic Triterpenes; Triterpenes

2005