betulinic acid and Glioma

betulinic acid has been researched along with Glioma in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bache, M; Emmerich, D; Güttler, A; Hein, A; Kappler, M; Keßler, J; Paschke, R; Petrenko, M; Vordermark, D; Wichmann, H1
Bai, X; Huo, L; Wang, M; Wang, Y1
Bähr, O; Fischer, S; Fulda, S; Harter, PN; Kögel, D; Mittelbronn, M; Paschke, R; Reichert, S; Ronellenfitsch, MW; Steinbach, JP; Thiepold, AL; Weller, M1
Amoroso, R; Bartoli, B; Benvenuti, L; Gagliardi, R; Gremigni, V; Lena, A; Rechichi, M; Rossi, L; Salvetti, A; Scarcelli, V; Vecchio, D1
Bache, M; Kaluđerović, GN; Kappler, M; Kessler, J; Kommera, H; Paschke, R; Passin, S; Taubert, H; Vordermark, D; Wichmann, H; Zschornak, MP1
Dichgans, J; Grimmel, C; Wagenknecht, B; Weller, M; Wick, W1

Other Studies

6 other study(ies) available for betulinic acid and Glioma

ArticleYear
Evaluation of the Betulinic Acid-Cisplatin conjugate APC and its precursor DE9B for the treatment of human malignant glioma.
    Chemico-biological interactions, 2019, Dec-01, Volume: 314

    Topics: Antineoplastic Agents; Apoptosis; Betulinic Acid; Caspase 3; Caspase 7; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Cell Survival; Cisplatin; Coordination Complexes; Glioma; Humans; Pentacyclic Triterpenes; Triterpenes

2019
Betulinic acid derivative B10 inhibits glioma cell proliferation through suppression of SIRT1, acetylation of FOXO3a and upregulation of Bim/PUMA.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 92

    Topics: Acetylation; Animals; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Betulinic Acid; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Forkhead Box Protein O3; Glioma; Glucosides; Humans; Mice; Mice, Nude; Pentacyclic Triterpenes; Proto-Oncogene Proteins; Sirtuin 1; Triterpenes; Up-Regulation; Xenograft Model Antitumor Assays

2017
Hypoxia enhances the antiglioma cytotoxicity of B10, a glycosylated derivative of betulinic acid.
    PloS one, 2014, Volume: 9, Issue:4

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Betulinic Acid; Cathepsin B; Cell Death; Cell Hypoxia; Cell Line, Tumor; Dacarbazine; Dipeptides; Glioma; Humans; Macrolides; Neoplasm Proteins; Pentacyclic Triterpenes; Temozolomide; Triterpenes

2014
Drugs targeting the mitochondrial pore act as cytotoxic and cytostatic agents in temozolomide-resistant glioma cells.
    Journal of translational medicine, 2009, Feb-05, Volume: 7

    Topics: Acridine Orange; Betulinic Acid; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Death; Cell Line, Tumor; Cell Survival; Cyclosporine; Cytostatic Agents; Dacarbazine; Drug Resistance, Neoplasm; ErbB Receptors; Glioma; Humans; Indazoles; Membrane Potential, Mitochondrial; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Pentacyclic Triterpenes; Polymerase Chain Reaction; Retinoids; Temozolomide; Triterpenes

2009
Increased betulinic acid induced cytotoxicity and radiosensitivity in glioma cells under hypoxic conditions.
    Radiation oncology (London, England), 2011, Sep-09, Volume: 6

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Betulinic Acid; Blotting, Western; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Survival; Gene Expression Regulation, Neoplastic; Glioma; Humans; Hypoxia; Pentacyclic Triterpenes; Radiation Tolerance; Radiation-Sensitizing Agents; Triterpenes; Wound Healing

2011
Betulinic acid-induced apoptosis in glioma cells: A sequential requirement for new protein synthesis, formation of reactive oxygen species, and caspase processing.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Betulinic Acid; Caspases; Cell Cycle; Cell Division; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; Cysteine Proteinase Inhibitors; DNA Fragmentation; Enzyme Activation; Fas Ligand Protein; fas Receptor; Glioma; Humans; Kinetics; Membrane Glycoproteins; Oligopeptides; Pentacyclic Triterpenes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Triterpenes; Tumor Cells, Cultured

1999