betulinic acid has been researched along with Disease Models, Animal in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.86) | 18.2507 |
| 2000's | 1 (2.86) | 29.6817 |
| 2010's | 25 (71.43) | 24.3611 |
| 2020's | 8 (22.86) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, Y; Hiep, NT; Hong, S; Hwang, BY; Kim, DW; Kwon, J; Lee, D; Lee, HJ; Mar, W | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Hung, HY; Li, JW; Ma, F; Wang, MS; Wang, N; Wang, Q; Wang, YL; Zheng, LY; Zou, M; Zou, X | 1 |
| Abrishamdar, M; Badavi, M; Farbood, Y; Rashno, M; Sarkaki, A | 1 |
| García-Martín, A; Lastres-Cubillo, I; Martínez-Orgado, J; Muñoz, E; Navarrete, C; Ponce-Díaz, F; Prados, ME | 1 |
| Chen, G; He, J; Ji, C; Liang, T; Lin, J; Liu, B; Liu, N; Liu, P; Luo, Z; Shi, K; Su, X; Wu, Y; Zhang, C; Zhou, Y | 1 |
| Guo, Y; Sun, L; Wang, C; Weng, M; Zhu, H | 1 |
| Ajibesin, K; Akpan, O; Archibong, B; De Leo, M; Eseyin, O; Essien, E; Etukudo, E; Flamini, G; Thomas, P; Udoh, A | 1 |
| Deng, X; Li, Y; Yue, Q; Zhang, Y | 1 |
| Gao, D; Liu, Y; Liu, Z; Luo, L; Wang, L; Wang, M; Wang, Q; Zhang, X | 1 |
| Badavi, M; Farbood, Y; Ghadiri, A; Mansouri, E; Navabi, SP; Sarkaki, A | 1 |
| Li, HG; Lu, P; Luo, AL; Tian, YK; Xu, H; Zhang, CC; Zhang, XM | 1 |
| Borkotoky, S; Busi, S; Mohanty, SK; Murali, A; Rajkumari, J; Suchiang, K | 1 |
| Akhtar, M; Deshmukh, R; Kaundal, M | 1 |
| Bellampalli, SS; Cai, S; Chefdeville, A; Chew, LA; Dorame, A; Gandini, MA; Gunatilaka, AAL; Ji, Y; Khanna, M; Khanna, R; Luo, S; Madura, CL; Molnar, G; Moutal, A; Streicher, JM; Wijeratne, EMK; Yu, J; Zamponi, GW | 1 |
| Baranovsky, AV; Khlebnicova, TS; Lakhvich, FA; Piven, YA; Sorokina, IV; Tolstikova, TG | 1 |
| Chen, J; Deng, L; Gong, Z; Han, L; Li, N; Li, X; Lin, C; Liu, D; Liu, Q; Ma, Q; Pan, D; Wang, Q; Wei, Z; Wu, M | 1 |
| Choi, BH; Fang, S; Hyun, CK; Jeon, J; Jung, HY; Kim, B; Kim, JB; Kim, KD; Kim, KT; Park, CH; Ryu, HG; Yang, SH; Yoo, HY | 1 |
| Barbosa-Filho, JM; Barreto, BC; Caria, ACI; Macambira, SG; Meira, CS; Moreira, DRM; Nonaka, CKV; Orge, ID; Santo, RFDE; Santos, ES; Silva, DN; Soares, MBP; Vasconcelos, JF | 1 |
| Afzal, M; Al-Abbasi, FA; Anwar, F; Kazmi, I; Semwal, S | 1 |
| Doddapaneni, R; Godugu, C; Patel, AR; Singh, M; Somagoni, J | 1 |
| Ayanur, A; Balaganur, V; Begum, J; Bhat, RA; Kumar, D; Lingaraju, MC; Pathak, NN; Ram, M; Ramachandra, HD; Singh, V; Tandan, SK | 1 |
| Balaganur, V; Begum, J; Bhat, RA; Kandasamy, K; Kumar, D; Lingaraju, MC; Pathak, NN; Ram, M; Ramachandra, HD; Singh, V; Tandan, SK | 1 |
| Dutta, SK; Ghosh, M; Saha, S | 1 |
| Chang, WC; Chen, YJ; Goto, M; Hsu, TI; Hung, CY; Hung, JJ; Kashiwada, Y; Kim, SY; Lai, MD; Lee, KH; Lin, SJ; Qian, K; Su, WC; Wang, Q; Wang, YC; Zhao, Y | 1 |
| Cho, N; Jeon, BJ; Kim, HW; Lee, HK; Sung, SH | 1 |
| Dey, YN; Jadhav, AD; Kumar, D; Lomash, V; Wanjari, MM | 1 |
| Clarinda, MM; Correa, MD; David, IM; Fernandes, FS; Florentino, D; Freitas, AF; Gava, M; Kanis, LA; Kviecinski, MR; Moterle, D; Müller, SD; Pedrosa, RC; Petronilho, F; Silva, JD | 1 |
| Liu, L; Shen, H; Wei, K; Xun, W; Yang, Y; Zeng, G | 1 |
| Alaoui, K; Asongalem, AE; Azebaze, AG; Cherrah, Y; Dimo, T; Dongmo, AB; Kamtchouing, P; Nguemfo, EL | 1 |
| Helen, A; Luxmi, VR; Viji, V | 1 |
| Lian, LH; Nan, JX; Song, SZ; Wan, Y; Wu, YL; Zheng, ZW | 1 |
| Chiu, TH; Lai, SC; Lee, CY; Peng, WH; Tsai, JC | 1 |
| Fu, JY; Liang, HT; Lu, HT; Lu, JF; Qian, LB; Tan, YN; Wang, HP; Xia, Q; Zhu, LG | 1 |
| Kirby, GC; Simmonds, MS; Steele, JC; Warhurst, DC | 1 |
35 other study(ies) available for betulinic acid and Disease Models, Animal
| Article | Year |
|---|---|
Chemical Constituents Isolated from the Root Bark of Cudrania tricuspidata and Their Potential Neuroprotective Effects.
Topics: Animals; Cell Death; Disease Models, Animal; Glucose; Ischemia; Moraceae; Neuroprotective Agents; Nuclear Magnetic Resonance, Biomolecular; Parkinson Disease; Plant Bark; Plant Roots; Republic of Korea; Xanthones | 2016 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Betulinic acid-nucleoside hybrid prevents acute alcohol -induced liver damage by promoting anti-oxidative stress and autophagy.
Topics: Acute Lung Injury; Animals; Antioxidants; Betulinic Acid; Central Nervous System Depressants; Disease Models, Animal; Ethanol; Liver; Liver Diseases, Alcoholic; Liver Function Tests; Mice; Nucleosides; Oxidative Stress; Pentacyclic Triterpenes; Protective Agents; Solubility | 2022 |
Evaluation of betulinic acid effects on pain, memory, anxiety, catalepsy, and oxidative stress in animal model of Parkinson's disease.
Topics: Animals; Antioxidants; Anxiety; Betulinic Acid; Brain-Derived Neurotrophic Factor; Catalepsy; Disease Models, Animal; Interleukin-10; Male; Models, Animal; Oxidative Stress; Oxidopamine; Pain; Parkinson Disease; Rats; Rats, Wistar; Superoxide Dismutase | 2023 |
VCE-005.1, an hypoxia mimetic betulinic acid derivative, induces angiogenesis and shows efficacy in a murine model of traumatic brain injury.
Topics: AMP-Activated Protein Kinases; Animals; Betulinic Acid; Blood-Brain Barrier; Brain Injuries, Traumatic; Disease Models, Animal; Endothelial Cells; Hypoxia; Mice; Mice, Inbred C57BL; Neuroinflammatory Diseases | 2023 |
Betulinic Acid Attenuates Osteoarthritis via Limiting NLRP3 Inflammasome Activation to Decrease Interleukin-1
Topics: Animals; Betulinic Acid; Disease Models, Animal; Inflammasomes; Interleukin-1beta; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Osteoarthritis | 2023 |
Chemopreventive effect of Betulinic acid via mTOR -Caspases/Bcl2/Bax apoptotic signaling in pancreatic cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Betulinic Acid; Caspases; Cell Line, Tumor; Disease Models, Animal; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Pentacyclic Triterpenes; Proto-Oncogene Proteins c-bcl-2; TOR Serine-Threonine Kinases; Triterpenes | 2020 |
Isolation and characterization of anti-inflammatory and analgesic compounds from Uapaca staudtii Pax (Phyllanthaceae) stem bark.
Topics: Africa, Western; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Behavior, Animal; Betulinic Acid; Disease Models, Animal; Edema; Female; Free Radical Scavengers; Hydroxybenzoates; Inflammation; Male; Mice; Pain; Pentacyclic Triterpenes; Phenol; Phyllanthus; Plant Bark; Plant Extracts | 2021 |
Effects of Betulinic Acid Derivative on Lung Inflammation in a Mouse Model of Chronic Obstructive Pulmonary Disease Induced by Particulate Matter 2.5.
Topics: Animals; Betulinic Acid; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Interleukin-6; Male; Mice; Oxidative Stress; Particulate Matter; Pentacyclic Triterpenes; Pneumonia; Pulmonary Disease, Chronic Obstructive; Tumor Necrosis Factor-alpha | 2021 |
Gold nanoshell-based betulinic acid liposomes for synergistic chemo-photothermal therapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Betulinic Acid; Bone Neoplasms; Combined Modality Therapy; Delayed-Action Preparations; Disease Models, Animal; Drug Therapy; Gold; Humans; Hyperthermia, Induced; Infrared Rays; Liposomes; Mice; Nanoshells; Osteosarcoma; Pentacyclic Triterpenes; Phototherapy; Triterpenes; Tumor Cells, Cultured | 2017 |
The effects of betulinic acid on neurobehavioral activity, electrophysiology and histological changes in an animal model of the Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Avoidance Learning; Betulinic Acid; Disease Models, Animal; Excitatory Postsynaptic Potentials; Hippocampus; Locomotion; Male; Mental Disorders; Neuropsychological Tests; Pentacyclic Triterpenes; Random Allocation; Rats; Rats, Wistar; Spatial Memory; Streptozocin; Swimming; Triterpenes | 2018 |
Down-regulation of NOX4 by betulinic acid protects against cerebral ischemia-reperfusion in mice.
Topics: Animals; Betulinic Acid; Brain Ischemia; Disease Models, Animal; Down-Regulation; Mice; NADPH Oxidase 4; Pentacyclic Triterpenes; Reactive Oxygen Species; Reperfusion Injury; Treatment Outcome; Triterpenes | 2017 |
Attenuation of quorum sensing controlled virulence factors and biofilm formation in Pseudomonas aeruginosa by pentacyclic triterpenes, betulin and betulinic acid.
Topics: Alginates; Animals; Anti-Bacterial Agents; Bacterial Adhesion; Bacterial Proteins; Betulinic Acid; Biofilms; Caenorhabditis elegans; Chitinases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Glucuronic Acid; Glycolipids; Hexuronic Acids; Hydrophobic and Hydrophilic Interactions; Indoles; Metalloendopeptidases; Metalloproteases; Microbial Sensitivity Tests; Microbial Viability; Molecular Docking Simulation; Molecular Dynamics Simulation; Pentacyclic Triterpenes; Polysaccharides, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Pyocyanine; Quorum Sensing; Survival Analysis; Trans-Activators; Triterpenes; Virulence; Virulence Factors | 2018 |
Protective effect of betulinic acid against intracerebroventricular streptozotocin induced cognitive impairment and neuronal damage in rats: Possible neurotransmitters and neuroinflammatory mechanism.
Topics: Acetylcholinesterase; Animals; Betulinic Acid; Cognitive Dysfunction; Disease Models, Animal; Donepezil; Glutathione; Hippocampus; Indans; Inflammation; Injections, Intraventricular; Male; Maze Learning; Memory; Memory Disorders; Neuroprotective Agents; Neurotransmitter Agents; Oxidative Stress; Pentacyclic Triterpenes; Piperidines; Rats; Rats, Wistar; Streptozocin; Triterpenes | 2018 |
Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury-associated peripheral sensory neuropathy via block of N- and T-type calcium channels.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Betulinic Acid; Calcium Channels, N-Type; Calcium Channels, T-Type; CHO Cells; Cricetulus; Diprenorphine; Disease Models, Animal; Female; Ganglia, Spinal; HIV Infections; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Inbred C57BL; Neuralgia; Neurons; Paclitaxel; Pentacyclic Triterpenes; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Triterpenes; Tritium | 2019 |
Fluorine-containing lupane triterpenoid acid derivatives: Design, synthesis and biological evaluation as potential anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Betulinic Acid; Concanavalin A; Disease Models, Animal; Drug Design; Edema; Female; Fluorine; Hepatitis; Histamine; Male; Mice; Mice, Inbred C57BL; Molecular Conformation; Pentacyclic Triterpenes; Tetracycline; Triterpenes | 2019 |
Betulinic acid inhibits the migration and invasion of fibroblast-like synoviocytes from patients with rheumatoid arthritis.
Topics: Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Arthritis, Rheumatoid; Betulinic Acid; Cell Movement; Cells, Cultured; Cytokines; Disease Models, Animal; Female; Fibroblasts; Humans; Inflammation; Male; Mice; Mice, Inbred DBA; Middle Aged; NF-kappa B; Pentacyclic Triterpenes; Signal Transduction; Synoviocytes; Triterpenes | 2019 |
Betulinic acid inhibits high-fat diet-induced obesity and improves energy balance by activating AMPK.
Topics: 3T3-L1 Cells; Adipocytes; Adiposity; AMP-Activated Protein Kinases; Animals; Anti-Obesity Agents; Betulinic Acid; Diet, High-Fat; Disease Models, Animal; Energy Metabolism; Enzyme Activation; Liver; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Pentacyclic Triterpenes; Phosphorylation; Signal Transduction; Triterpenes; Weight Gain | 2019 |
Betulinic Acid Derivative BA5, Attenuates Inflammation and Fibrosis in Experimental Chronic Chagas Disease Cardiomyopathy by Inducing IL-10 and M2 Polarization.
Topics: Animals; Anti-Inflammatory Agents; Betulinic Acid; Chagas Cardiomyopathy; Chronic Disease; Disease Models, Animal; Fibrosis; Inflammation; Interleukin-10; Macrophages; Mice; Pentacyclic Triterpenes; Triterpenes; Trypanosoma cruzi | 2019 |
Therapeutic exploration of betulinic acid in chemically induced hypothyroidism.
Topics: Animals; Betulinic Acid; Blood Sedimentation; Disease Models, Animal; Female; Hypothyroidism; Pentacyclic Triterpenes; Platelet Count; Rats; Rats, Wistar; Triterpenes | 2014 |
Approaches to improve the oral bioavailability and effects of novel anticancer drugs berberine and betulinic acid.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Berberine; Betulinic Acid; Biological Availability; Blotting, Western; Cell Death; Cell Line, Tumor; Cell Membrane Permeability; Chemistry, Pharmaceutical; Clone Cells; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Lung Neoplasms; Mice, Nude; Pentacyclic Triterpenes; Rats, Sprague-Dawley; Triterpenes; Vascular Endothelial Growth Factor A | 2014 |
Betulinic acid attenuates lung injury by modulation of inflammatory cytokine response in experimentally-induced polymicrobial sepsis in mice.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Betulinic Acid; Cecum; Coinfection; Cytokines; Disease Models, Animal; Intercellular Adhesion Molecule-1; Lung; Matrix Metalloproteinase 9; Mice; NF-kappa B; Pentacyclic Triterpenes; Sepsis; Triterpenes | 2015 |
Betulinic acid attenuates renal oxidative stress and inflammation in experimental model of murine polymicrobial sepsis.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Betulinic Acid; Coinfection; Disease Models, Animal; Inflammation; Male; Mice; Oxidative Stress; Pentacyclic Triterpenes; Sepsis; Triterpenes | 2015 |
A potent tumoricidal co-drug 'Bet-CA'--an ester derivative of betulinic acid and dichloroacetate selectively and synergistically kills cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Betulinic Acid; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dichloroacetic Acid; Disease Models, Animal; Drug Synergism; Esters; Female; Humans; Inhibitory Concentration 50; Lung Neoplasms; Melanoma; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mitochondria; NIH 3T3 Cells; Oxidative Stress; Pentacyclic Triterpenes; Reactive Oxygen Species; Triterpenes | 2015 |
A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy.
Topics: Animals; Antineoplastic Agents; Betulinic Acid; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, SCID; Mice, Transgenic; Neoplasm Metastasis; Pentacyclic Triterpenes; Prognosis; Transfection; Triterpenes; Xenograft Model Antitumor Assays | 2015 |
Ameliorative effect of betulin from Betula platyphylla bark on scopolamine-induced amnesic mice.
Topics: Administration, Oral; Alzheimer Disease; Amnesia; Animals; Avoidance Learning; Betula; Betulinic Acid; Cognition; Disease Models, Animal; Glutathione; Hippocampus; Humans; Male; Maze Learning; Memory; Mice; Neuroprotective Agents; Nootropic Agents; Pentacyclic Triterpenes; Plant Bark; Plant Extracts; Scopolamine; Triterpenes | 2016 |
Curative effect of Amorphophallus paeoniifolius tuber on experimental hemorrhoids in rats.
Topics: Amorphophallus; Anal Canal; Animals; Anti-Inflammatory Agents; Antioxidants; Betulinic Acid; Biomarkers; Chromatography, High Pressure Liquid; Croton Oil; Disease Models, Animal; Hemorrhoids; Inflammation Mediators; Interleukin-6; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Methanol; Pentacyclic Triterpenes; Peroxidase; Plant Extracts; Plant Tubers; Rats, Wistar; Rectum; Remission Induction; Severity of Illness Index; Solvents; Triterpenes; Tumor Necrosis Factor-alpha; Water | 2016 |
Healing effect of Dillenia indica fruit extracts standardized to betulinic acid on ultraviolet radiation-induced psoriasis-like wounds in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Betulinic Acid; Biomarkers; Clobetasol; Dermatologic Agents; Dilleniaceae; Disease Models, Animal; Fruit; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Pentacyclic Triterpenes; Phytotherapy; Plant Extracts; Plants, Medicinal; Protein Carbonylation; Psoriasis; Rats, Wistar; Skin; Solvents; Time Factors; Triterpenes; Ultraviolet Rays; Wound Healing | 2017 |
Betulinic Acid Inhibits Cell Proliferation in Human Oral Squamous Cell Carcinoma via Modulating ROS-Regulated p53 Signaling.
Topics: Animals; Antineoplastic Agents, Phytogenic; Betulinic Acid; Carcinoma, Squamous Cell; Caspase 3; Caspase 9; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Genes, Reporter; Humans; Male; Mice; Mouth Neoplasms; Pentacyclic Triterpenes; Reactive Oxygen Species; Signal Transduction; STAT3 Transcription Factor; Triterpenes; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2017 |
Anti-oxidative and anti-inflammatory activities of some isolated constituents from the stem bark of Allanblackia monticola Staner L.C (Guttiferae).
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Betulinic Acid; Carrageenan; Clusiaceae; Disease Models, Animal; Female; Free Radical Scavengers; Inflammation; Inhibitory Concentration 50; Male; Pentacyclic Triterpenes; Plant Bark; Plant Extracts; Rats; Rats, Wistar; Triterpenes; Xanthones | 2009 |
Betulinic acid inhibits endotoxin-stimulated phosphorylation cascade and pro-inflammatory prostaglandin E(2) production in human peripheral blood mononuclear cells.
Topics: Animals; Betulinic Acid; Disease Models, Animal; Electrophoretic Mobility Shift Assay; Endotoxins; Humans; Inflammation; Leukocytes, Mononuclear; Male; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Pentacyclic Triterpenes; Peroxidase; Phosphorylation; Prostaglandins E; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Sepsis; Shock, Septic; Triterpenes | 2011 |
Betulinic acid prevention of d-galactosamine/lipopolysaccharide liver toxicity is triggered by activation of Bcl-2 and antioxidant mechanisms.
Topics: Alanine Transaminase; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Betulinic Acid; Caspase 3; Catalase; Disease Models, Animal; Galactosamine; Glutathione; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Liver Failure, Acute; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Pentacyclic Triterpenes; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Survival Analysis; Triterpenes; Up-Regulation | 2011 |
Anti-inflammatory effects of Scoparia dulcis L. and betulinic acid.
Topics: Animals; Anti-Inflammatory Agents; Betulinic Acid; Cyclooxygenase 2; Disease Models, Animal; Edema; Humans; Interleukin-1beta; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Pentacyclic Triterpenes; Plant Extracts; Scoparia; Triterpenes; Tumor Necrosis Factor-alpha | 2011 |
Betulinic acid ameliorates endothelium-dependent relaxation in L-NAME-induced hypertensive rats by reducing oxidative stress.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Betulinic Acid; Data Interpretation, Statistical; Disease Models, Animal; Endothelium, Vascular; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Pentacyclic Triterpenes; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Triterpenes; Vasodilation | 2011 |
In vitro and in vivo evaluation of betulinic acid as an antimalarial.
Topics: Animals; Antimalarials; Betulinic Acid; Disease Models, Animal; Euphorbiaceae; Malaria; Mice; Microbial Sensitivity Tests; Oleanolic Acid; Pentacyclic Triterpenes; Phytotherapy; Plant Extracts; Plant Roots; Plasmodium berghei; Plasmodium falciparum; Random Allocation; Structure-Activity Relationship; Triterpenes; Ursolic Acid | 1999 |