betulinic acid and Colorectal Cancer

betulinic acid has been researched along with Colorectal Cancer in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's4 (40.00)24.3611
2020's5 (50.00)2.80

Authors

AuthorsStudies
Hua, H; Liu, L; Zeng, A; Zhao, J1
Cunha, NL; Cunha, WR; de A E Silva, ML; de Freitas, KS; de Melo, MRS; do Nascimento, S; Fernandes, FS; Ferreira, NH; Ribeiro, AB; Tavares, DC1
Apisawetakan, S; Chaithirayanon, K; Nantasenamat, C; Nobsathian, S; Yurasakpong, L1
Chowdhury, C; Debnath, MC; Dutta, D; Mondal, L; Mukherjee, B; Paul, B; Sen, S1
Wang, G; Wang, YZ; Xu, K; Yin, PH; Yu, Y1
Wang, G; Wang, YZ; Xu, K; Yin, PH; Yu, Y; Zhu, ZM1
Bu, Y; Lei, Y; Li, Y; Song, F; Wang, K; Wang, S; Wang, Y; Xu, Q; Zhang, C; Zhang, W; Zhang, Y; Zhu, H1
Wang, G; Wang, JJ; Wang, YZ; Xu, K; Yin, PH; Yu, Y1
Abu-Salah, KM; Aisha, AF; Ismail, Z; Majid, AM1
de Roo, GM; Kessler, JH; Medema, JP; Mullauer, FB1

Other Studies

10 other study(ies) available for betulinic acid and Colorectal Cancer

ArticleYear
Betulinic acid induces apoptosis and inhibits metastasis of human colorectal cancer cells in vitro and in vivo.
    Bioorganic & medicinal chemistry, 2019, 06-15, Volume: 27, Issue:12

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Betulinic Acid; Caspase 3; Cell Line, Tumor; Cell Movement; Colorectal Neoplasms; Down-Regulation; Humans; Matrix Metalloproteinases; Mice; Mice, Nude; Pentacyclic Triterpenes; Triterpenes; Up-Regulation; Xenograft Model Antitumor Assays

2019
Betulinic acid exerts antigenotoxic and anticarcinogenic activities via inhibition of COX-2 and PCNA in rodents.
    Journal of biochemical and molecular toxicology, 2021, Volume: 35, Issue:12

    Topics: Animals; Anticarcinogenic Agents; Antimutagenic Agents; Betulinic Acid; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Doxorubicin; Inflammation; Male; Mice; Pentacyclic Triterpenes; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Signal Transduction

2021
Betulinic Acid Modulates the Expression of HSPA and Activates Apoptosis in Two Cell Lines of Human Colorectal Cancer.
    Molecules (Basel, Switzerland), 2021, Oct-22, Volume: 26, Issue:21

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Betulinic Acid; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug; Flow Cytometry; Gene Expression Regulation, Neoplastic; HSP70 Heat-Shock Proteins; Humans; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Pentacyclic Triterpenes; Structure-Activity Relationship

2021
Nanoencapsulated betulinic acid analogue distinctively improves colorectal carcinoma in vitro and in vivo.
    Scientific reports, 2019, 08-08, Volume: 9, Issue:1

    Topics: Betulinic Acid; Colorectal Neoplasms; Drug Compounding; HEK293 Cells; HT29 Cells; Humans; Membrane Potential, Mitochondrial; Nanostructures; Particle Size; Pentacyclic Triterpenes; Spectroscopy, Fourier Transform Infrared; Triterpenes

2019
The Antitumor Activity of Betulinic Acid-Loaded Nanoliposomes Against Colorectal Cancer
    Journal of biomedical nanotechnology, 2020, Feb-01, Volume: 16, Issue:2

    Topics: Betulinic Acid; Colorectal Neoplasms; Drug Delivery Systems; Glycolysis; Humans; Pentacyclic Triterpenes; Triterpenes

2020
Effects and mechanisms of fatty acid metabolism‑mediated glycolysis regulated by betulinic acid‑loaded nanoliposomes in colorectal cancer.
    Oncology reports, 2020, Volume: 44, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Betulinic Acid; Carnitine O-Palmitoyltransferase; Carrier Proteins; Coenzyme A Ligases; Colorectal Neoplasms; Fatty Acids; HCT116 Cells; Humans; Liposomes; Membrane Proteins; Nanoparticles; Pentacyclic Triterpenes; Signal Transduction; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Warburg Effect, Oncologic

2020
Overaccumulation of p53-mediated autophagy protects against betulinic acid-induced apoptotic cell death in colorectal cancer cells.
    Cell death & disease, 2017, 10-05, Volume: 8, Issue:10

    Topics: Apoptosis; Autophagy; Autophagy-Related Protein 5; Betulinic Acid; Cell Proliferation; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Mutation; Pentacyclic Triterpenes; RNA, Small Interfering; Signal Transduction; Triterpenes; Tumor Suppressor Protein p53

2017
Triterpenoids Extracted from
    Nutrition and cancer, 2020, Volume: 72, Issue:2

    Topics: Animals; Apoptosis; Betulinic Acid; Cell Line, Tumor; Cell Proliferation; Chromatography, Liquid; Colorectal Neoplasms; Flavonoids; Gene Regulatory Networks; Glutamine; Glycolysis; Humans; Male; Metabolome; Mice; Mice, Inbred BALB C; Mice, Nude; Pentacyclic Triterpenes; Plant Extracts; Rhus; Tandem Mass Spectrometry; Triterpenes; Validation Studies as Topic; Xenograft Model Antitumor Assays

2020
alpha-Mangostin enhances betulinic acid cytotoxicity and inhibits cisplatin cytotoxicity on HCT 116 colorectal carcinoma cells.
    Molecules (Basel, Switzerland), 2012, Mar-08, Volume: 17, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Betulinic Acid; Caspase 3; Caspase 7; Cell Proliferation; Cell Shape; Cell Survival; Chromatin; Cisplatin; Colorectal Neoplasms; Cytoprotection; Drug Synergism; HCT116 Cells; Humans; Inhibitory Concentration 50; Membrane Potential, Mitochondrial; Pentacyclic Triterpenes; Signal Transduction; Triterpenes; Xanthones

2012
Broad in vitro efficacy of plant-derived betulinic acid against cell lines derived from the most prevalent human cancer types.
    Cancer letters, 2007, Jun-18, Volume: 251, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Betulinic Acid; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cells, Cultured; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Humans; Jurkat Cells; Lung Neoplasms; Male; Neoplasms; Pentacyclic Triterpenes; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Triterpenes; Uterine Cervical Neoplasms

2007