betulinic acid has been researched along with Cancer of Lung in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 9 (56.25) | 24.3611 |
| 2020's | 5 (31.25) | 2.80 |
| Authors | Studies |
|---|---|
| Ling, Y; Liu, X; Luo, W; Meng, C; Qian, J; Shan, W; Xu, Z; Zhang, W; Zhu, P | 1 |
| Cai, N; Jin, X; Yang, Q; Zhang, Z | 1 |
| Mu, X; You, Q; Zhang, X; Zhao, H | 1 |
| Kutkowska, J; Rapak, A; Strzadala, L | 1 |
| Chen, YF; Fan, XZ; He, DH; Hong, M; Li, SY; Liu, YQ; Lu, Y; Wang, Q; Wei, SF; Yu, X; Zhang, SB; Zhou, YL | 1 |
| Abdul Wahab, N; Cheow, YL; Manickam, S; Navanesan, S; Sim, KS | 1 |
| Chou, CH; Jhan, YL; Tsai, SJ; Wang, CM; Yeh, KL | 1 |
| Chang, HY; Chen, HC; Chien, PJ; Hung, WH; Ko, JL; Lin, CH; Wang, BY | 1 |
| Doddapaneni, R; Godugu, C; Patel, AR; Singh, M; Somagoni, J | 1 |
| Amaar, YG; Chen, ST; Firek, M; Reeves, ME | 1 |
| Dutta, SK; Ghosh, M; Saha, S | 1 |
| Chang, WC; Chen, YJ; Goto, M; Hsu, TI; Hung, CY; Hung, JJ; Kashiwada, Y; Kim, SY; Lai, MD; Lee, KH; Lin, SJ; Qian, K; Su, WC; Wang, Q; Wang, YC; Zhao, Y | 1 |
| Daalhuisen, JB; Kessler, JH; Medema, JP; Mullauer, FB; Schiffelers, RM; Storm, G; Ten Brink, MS; van Bloois, L | 1 |
| Chang, WC; Chen, SY; Hsu, TI; Huang, ST; Hung, JJ; Su, WC; Wang, MC; Yeh, YM | 1 |
| Arimochi, H; Fujino, H; Kataoka, K; Kondo, K; Kuwahara, T; Miyoshi, T; Monden, Y; Ohnishi, Y; Sawada, N; Takahashi, Y | 1 |
| de Roo, GM; Kessler, JH; Medema, JP; Mullauer, FB | 1 |
16 other study(ies) available for betulinic acid and Cancer of Lung
| Article | Year |
|---|---|
GSH/ROS Dual-Responsive Supramolecular Nanoparticles Based on Pillar[6]arene and Betulinic Acid Prodrug for Chemo-Chemodynamic Combination Therapy.
Topics: Antineoplastic Agents, Phytogenic; Betulinic Acid; Breast Neoplasms; Drug Therapy, Combination; Female; Glutathione; Humans; Lung Neoplasms; Nanoparticles; Pentacyclic Triterpenes; Prodrugs; Quaternary Ammonium Compounds; Reactive Oxygen Species; Tumor Cells, Cultured | 2021 |
A cocktail of betulinic acid, parthenolide, honokiol and ginsenoside Rh2 in liposome systems for lung cancer treatment.
Topics: A549 Cells; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Betulinic Acid; Biphenyl Compounds; Cell Proliferation; Cisplatin; Ginsenosides; Humans; Lignans; Liposomes; Lung Neoplasms; Mice; Neoplasm Invasiveness; Pentacyclic Triterpenes; Sesquiterpenes; Triterpenes; Xenograft Model Antitumor Assays | 2020 |
Lung Cancer Inhibition by Betulinic Acid Nanoparticles via Adenosine 5'-Triphosphate (ATP)-Binding Cassette Transporter G1 Gene Downregulation.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily G, Member 1; Betulinic Acid; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Nanoparticles; Pentacyclic Triterpenes; Triterpenes | 2020 |
Hypoxia increases the apoptotic response to betulinic acid and betulin in human non-small cell lung cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Betulinic Acid; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Pentacyclic Triterpenes; Triterpenes; Tumor Hypoxia | 2021 |
Phytochemical library screening reveals betulinic acid as a novel Skp2-SCF E3 ligase inhibitor in non-small cell lung cancer.
Topics: A549 Cells; Animals; Antineoplastic Agents, Phytogenic; Betulinic Acid; Binding Sites; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Early Detection of Cancer; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Lung Neoplasms; Male; Mice; Pentacyclic Triterpenes; Protein Binding; S-Phase Kinase-Associated Proteins; Xenograft Model Antitumor Assays | 2021 |
Intrinsic capabilities of Leptospermum javanicum in inducing apoptosis and suppressing the metastatic potential of human lung carcinoma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Betulinic Acid; Carcinoma, Non-Small-Cell Lung; Cell Death; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Leptospermum; Lung Neoplasms; Molecular Structure; Neoplasm Metastasis; Pentacyclic Triterpenes; Structure-Activity Relationship; Triterpenes | 2017 |
Anti-Proliferative Activity of Triterpenoids and Sterols Isolated from Alstonia scholaris against Non-Small-Cell Lung Carcinoma Cells.
Topics: A549 Cells; Alstonia; Antineoplastic Agents; Betulinic Acid; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Humans; Lung Neoplasms; Pentacyclic Triterpenes; Phytosterols; Plant Extracts; Plant Leaves; Sterols; Tetrazolium Salts; Thiazoles; Triterpenes; Ursolic Acid | 2017 |
Effects and mechanisms of betulinic acid on improving EGFR TKI-resistance of lung cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Betulinic Acid; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Erlotinib Hydrochloride; Humans; Lung Neoplasms; Pentacyclic Triterpenes; Protein Kinase Inhibitors; Signal Transduction; Triterpenes | 2018 |
Approaches to improve the oral bioavailability and effects of novel anticancer drugs berberine and betulinic acid.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Berberine; Betulinic Acid; Biological Availability; Blotting, Western; Cell Death; Cell Line, Tumor; Cell Membrane Permeability; Chemistry, Pharmaceutical; Clone Cells; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Lung Neoplasms; Mice, Nude; Pentacyclic Triterpenes; Rats, Sprague-Dawley; Triterpenes; Vascular Endothelial Growth Factor A | 2014 |
Evidence that RASSF1C stimulation of lung cancer cell proliferation depends on IGFBP-5 and PIWIL1 expression levels.
Topics: Antineoplastic Agents; Argonaute Proteins; beta Catenin; Betulinic Acid; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Insulin-Like Growth Factor Binding Protein 5; Lung Neoplasms; Pentacyclic Triterpenes; Pyrazoles; Pyrimidines; Signal Transduction; Spheroids, Cellular; Triterpenes; Tumor Suppressor Proteins | 2014 |
A potent tumoricidal co-drug 'Bet-CA'--an ester derivative of betulinic acid and dichloroacetate selectively and synergistically kills cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Betulinic Acid; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dichloroacetic Acid; Disease Models, Animal; Drug Synergism; Esters; Female; Humans; Inhibitory Concentration 50; Lung Neoplasms; Melanoma; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mitochondria; NIH 3T3 Cells; Oxidative Stress; Pentacyclic Triterpenes; Reactive Oxygen Species; Triterpenes | 2015 |
A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy.
Topics: Animals; Antineoplastic Agents; Betulinic Acid; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, SCID; Mice, Transgenic; Neoplasm Metastasis; Pentacyclic Triterpenes; Prognosis; Transfection; Triterpenes; Xenograft Model Antitumor Assays | 2015 |
Betulinic acid delivered in liposomes reduces growth of human lung and colon cancers in mice without causing systemic toxicity.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Betulinic Acid; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Delivery Systems; Drug Stability; Female; Humans; Injections, Intravenous; Liposomes; Lung; Lung Neoplasms; Mice; Mice, Nude; Mitochondria; Pentacyclic Triterpenes; Rhodamines; Triterpenes | 2011 |
Betulinic acid decreases specificity protein 1 (Sp1) level via increasing the sumoylation of sp1 to inhibit lung cancer growth.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Betulinic Acid; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cyclin A2; Cysteine Endopeptidases; Down-Regulation; Endopeptidases; Female; HeLa Cells; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Mice, Transgenic; Nuclear Proteins; Pentacyclic Triterpenes; Phosphorylation; Plicamycin; Proteasome Endopeptidase Complex; Retinoblastoma Protein; Sp1 Transcription Factor; Sumoylation; Transcription Factors; Transcriptome; Triterpenes; Ubiquitin; Ubiquitin-Protein Ligases; Xenograft Model Antitumor Assays | 2012 |
Betulinic acid augments the inhibitory effects of vincristine on growth and lung metastasis of B16F10 melanoma cells in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Betulinic Acid; Cell Cycle; Female; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Pentacyclic Triterpenes; Skin Neoplasms; Triterpenes; Tumor Cells, Cultured; Vincristine | 2004 |
Broad in vitro efficacy of plant-derived betulinic acid against cell lines derived from the most prevalent human cancer types.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Betulinic Acid; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cells, Cultured; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Humans; Jurkat Cells; Lung Neoplasms; Male; Neoplasms; Pentacyclic Triterpenes; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Triterpenes; Uterine Cervical Neoplasms | 2007 |