betulinic acid and Adenocarcinoma

betulinic acid has been researched along with Adenocarcinoma in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (25.00)29.6817
2010's7 (58.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Kim, DS; Kim, JY; Koo, HM1
Alla, PK; Avram, S; Coricovac, D; Cretu, OM; Dehelean, C; Farcas, CG; Ghiulai, R; Loghin, F; Mioc, M; Moaca, EA; Pavel, I; Pinzaru, IA; Socoliuc, V; Soica, C1
Chang, HY; Chiu, CF; Huang, CY; Huang, SY; Kuo, TT; Lee, HC; Mau, CZ1
Kutkowska, J; Rapak, A; Strzadala, L1
Das, J; Das, S; Khuda-Bukhsh, AR; Paul, A; Samadder, A1
Karna, E; Palka, JA1
Chen, Y; Cheng, YQ; Fang, J; He, J; Ma, Q; Wu, QL; Yang, LJ1
Karna, E; Palka, JA; Szoka, L1
Alexa, E; Aluas, M; Dehelean, CA; Kása, P; Peev, C; Soica, CM; Zupkó, I1
Chang, DZ; Gao, Y; Huang, S; Jia, Z; Kong, X; Le, X; Li, Q; Suyun, H; Wang, L; Wei, D; Xie, K1
Chang, WC; Chen, SY; Hsu, TI; Huang, ST; Hung, JJ; Su, WC; Wang, MC; Yeh, YM1
Choi, CH; Han, HK; Han, SI; Jung, GR; Kim, KJ; Lee, TB; Lim, SC1

Other Studies

12 other study(ies) available for betulinic acid and Adenocarcinoma

ArticleYear
Development of C-20 modified betulinic acid derivatives as antitumor agents.
    Bioorganic & medicinal chemistry letters, 2001, Sep-03, Volume: 11, Issue:17

    Topics: Adenocarcinoma; Antineoplastic Agents; Betulinic Acid; Drug Screening Assays, Antitumor; Humans; Male; Melanoma; Oleanolic Acid; Pentacyclic Triterpenes; Prostatic Neoplasms; Structure-Activity Relationship; Triterpenes; Tumor Cells, Cultured

2001
Thermosensitive Betulinic Acid-Loaded Magnetoliposomes: A Promising Antitumor Potential for Highly Aggressive Human Breast Adenocarcinoma Cells Under Hyperthermic Conditions.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Betulinic Acid; Breast Neoplasms; Cell Line, Tumor; Chick Embryo; Chorioallantoic Membrane; Drug Liberation; Female; Humans; Hyperthermia, Induced; Iron; Liposomes; Magnetic Phenomena; Metal Nanoparticles; Microtubules; Pentacyclic Triterpenes; Spectrum Analysis, Raman

2020
Betulinic Acid Affects the Energy-Related Proteomic Profiling in Pancreatic Ductal Adenocarcinoma Cells.
    Molecules (Basel, Switzerland), 2021, Apr-24, Volume: 26, Issue:9

    Topics: Adenocarcinoma; Betulinic Acid; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Oxidative Phosphorylation; Pentacyclic Triterpenes; Proteome; Proteomics; Tandem Mass Spectrometry

2021
Sorafenib in Combination with Betulinic Acid Synergistically Induces Cell Cycle Arrest and Inhibits Clonogenic Activity in Pancreatic Ductal Adenocarcinoma Cells.
    International journal of molecular sciences, 2018, Oct-19, Volume: 19, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Agents; Betulinic Acid; Cell Cycle Checkpoints; Cell Line, Tumor; Drug Synergism; Humans; Pancreatic Neoplasms; Pentacyclic Triterpenes; Sorafenib; Triterpenes; Tumor Stem Cell Assay

2018
Strong anticancer potential of nano-triterpenoid from Phytolacca decandra against A549 adenocarcinoma via a Ca(2+)-dependent mitochondrial apoptotic pathway.
    Journal of acupuncture and meridian studies, 2014, Volume: 7, Issue:3

    Topics: Adenocarcinoma; Adenosine Triphosphatases; Antineoplastic Agents, Phytogenic; Apoptosis; Betulinic Acid; Biological Availability; Calcium; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Humans; Membrane Potential, Mitochondrial; Mitochondria; Nanoparticles; Oxidative Phosphorylation; Pentacyclic Triterpenes; Phytolacca; Phytotherapy; Plant Extracts; Triterpenes

2014
Mechanism of betulinic acid inhibition of collagen biosynthesis in human endometrial adenocarcinoma cells.
    Neoplasma, 2009, Volume: 56, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Betulinic Acid; Blotting, Western; Cell Survival; Collagen; Endometrial Neoplasms; Extracellular Signal-Regulated MAP Kinases; Female; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrin alpha2beta1; NF-kappa B; Pentacyclic Triterpenes; Proline; Receptor, IGF Type 1; Signal Transduction; Son of Sevenless Proteins; Triterpenes; Tumor Cells, Cultured

2009
Effect of betulinic acid on the regulation of Hiwi and cyclin B1 in human gastric adenocarcinoma AGS cells.
    Acta pharmacologica Sinica, 2010, Volume: 31, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Argonaute Proteins; Betulinic Acid; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin B1; Dose-Response Relationship, Drug; Down-Regulation; Flow Cytometry; Humans; Inhibitory Concentration 50; Pentacyclic Triterpenes; Proteins; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Time Factors; Triterpenes

2010
Betulinic acid inhibits the expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor in human endometrial adenocarcinoma cells.
    Molecular and cellular biochemistry, 2010, Volume: 340, Issue:1-2

    Topics: Adenocarcinoma; Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Betulinic Acid; Cell Line, Tumor; Collagen; Dipeptidases; Dose-Response Relationship, Drug; Down-Regulation; Endometrial Neoplasms; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Integrin alpha1; Integrin alpha2; Integrin beta1; Pentacyclic Triterpenes; Triterpenes; Vascular Endothelial Growth Factor A

2010
Physico-chemical comparison of betulinic acid, betulin and birch bark extract and in vitro investigation of their cytotoxic effects towards skin epidermoid carcinoma (A431), breast carcinoma (MCF7) and cervix adenocarcinoma (HeLa) cell lines.
    Natural product research, 2012, Volume: 26, Issue:10

    Topics: Adenocarcinoma; Betula; Betulinic Acid; Breast Neoplasms; Cell Line, Tumor; Female; HeLa Cells; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Pentacyclic Triterpenes; Plant Extracts; Skin Neoplasms; Triterpenes; Uterine Cervical Neoplasms

2012
Combining betulinic acid and mithramycin a effectively suppresses pancreatic cancer by inhibiting proliferation, invasion, and angiogenesis.
    Cancer research, 2011, Aug-01, Volume: 71, Issue:15

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Betulinic Acid; Cell Division; Cell Line, Tumor; Collagen; Drug Combinations; Drug Screening Assays, Antitumor; Drug Synergism; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Laminin; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neovascularization, Pathologic; Pancreatic Neoplasms; Pentacyclic Triterpenes; Plicamycin; Promoter Regions, Genetic; Proteoglycans; Recombinant Fusion Proteins; Sp1 Transcription Factor; Triterpenes; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2011
Betulinic acid decreases specificity protein 1 (Sp1) level via increasing the sumoylation of sp1 to inhibit lung cancer growth.
    Molecular pharmacology, 2012, Volume: 82, Issue:6

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Betulinic Acid; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cyclin A2; Cysteine Endopeptidases; Down-Regulation; Endopeptidases; Female; HeLa Cells; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Mice, Transgenic; Nuclear Proteins; Pentacyclic Triterpenes; Phosphorylation; Plicamycin; Proteasome Endopeptidase Complex; Retinoblastoma Protein; Sp1 Transcription Factor; Sumoylation; Transcription Factors; Transcriptome; Triterpenes; Ubiquitin; Ubiquitin-Protein Ligases; Xenograft Model Antitumor Assays

2012
Effect of betulinic acid on anticancer drug-resistant colon cancer cells.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 101, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Agents; bcl-2-Associated X Protein; bcl-Associated Death Protein; Betulinic Acid; Camptothecin; Caspases; Cell Death; Cell Line, Tumor; Colonic Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Fluorouracil; Humans; Irinotecan; Mitochondria; Multidrug Resistance-Associated Proteins; Organoplatinum Compounds; Oxaliplatin; Pentacyclic Triterpenes; Triterpenes

2007