Page last updated: 2024-08-25

betulin and Lung Neoplasms

betulin has been researched along with Lung Neoplasms in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's6 (60.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Cai, J; Ding, XB; Gong, YS; Wang, JN; Yan, WY1
Han, YH; Hong, SH; Jeon, HD; Kee, JY; Mun, JG1
Kutkowska, J; Rapak, A; Strzadala, L1
Chou, CH; Jhan, YL; Tsai, SJ; Wang, CM; Yeh, KL1
Gauthier, C; Legault, J; Mihoub, M; Pichette, A; Sylla, B1
Han, JC; Li, XD; Zhang, YJ1
Boldyrev, VV; Chesnokov, NV; Kuznetsov, BN; Kuznetsova, SA; Malyar, YN; Mikhailenko, MA; Shakhtshneider, TP; Spivak, EA; Zamay, AS; Zamay, TN1
Huang, G; Jia, W; Li, J; Liu, J; Liu, L; Miao, P; Song, S; Sun, X; Yan, H; Yang, H; Zhao, L; Zhao, X; Zhou, X1
Hong, SS; Kim, DK; Kwon, SW; Lee, JG; Lee, YY; Park, JH; Pyo, JS; Roh, SH1
Bouchard, J; Dufour, P; Gauthier, C; Legault, J; Pichette, A; Thibeault, D1

Other Studies

10 other study(ies) available for betulin and Lung Neoplasms

ArticleYear
Co-treatment of betulin and gefitinib is effective against EGFR wild-type/KRAS-mutant non-small cell lung cancer by inducing ferroptosis.
    Neoplasma, 2022, Volume: 69, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; ErbB Receptors; Ferroptosis; Gefitinib; Humans; Lung Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); Reactive Oxygen Species; Triterpenes

2022
Betulin Inhibits Lung Metastasis by Inducing Cell Cycle Arrest, Autophagy, and Apoptosis of Metastatic Colorectal Cancer Cells.
    Nutrients, 2019, Dec-26, Volume: 12, Issue:1

    Topics: Animals; Apoptosis; Autophagy; Cell Cycle Checkpoints; Cell Line, Tumor; Colonic Neoplasms; Humans; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Triterpenes

2019
Hypoxia increases the apoptotic response to betulinic acid and betulin in human non-small cell lung cancer cells.
    Chemico-biological interactions, 2021, Jan-05, Volume: 333

    Topics: Antineoplastic Agents; Apoptosis; Betulinic Acid; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Pentacyclic Triterpenes; Triterpenes; Tumor Hypoxia

2021
Anti-Proliferative Activity of Triterpenoids and Sterols Isolated from Alstonia scholaris against Non-Small-Cell Lung Carcinoma Cells.
    Molecules (Basel, Switzerland), 2017, Dec-01, Volume: 22, Issue:12

    Topics: A549 Cells; Alstonia; Antineoplastic Agents; Betulinic Acid; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Humans; Lung Neoplasms; Pentacyclic Triterpenes; Phytosterols; Plant Extracts; Plant Leaves; Sterols; Tetrazolium Salts; Thiazoles; Triterpenes; Ursolic Acid

2017
Bidesmosidic betulin saponin bearing L-rhamnopyranoside moieties induces apoptosis and inhibition of lung cancer cells growth in vitro and in vivo.
    PloS one, 2018, Volume: 13, Issue:3

    Topics: A549 Cells; Animals; Apoptosis; Caspases; Cell Line, Tumor; Cell Proliferation; DNA Fragmentation; Electron Transport Chain Complex Proteins; G2 Phase Cell Cycle Checkpoints; Humans; Lung Neoplasms; M Phase Cell Cycle Checkpoints; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mitochondria; Reactive Oxygen Species; Rhamnose; Rotenone; Saponins; Transplantation, Heterologous; Triterpenes

2018
Betulin inhibits lung carcinoma proliferation through activation of AMPK signaling.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2014, Volume: 35, Issue:11

    Topics: AMP-Activated Protein Kinases; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Humans; Lung Neoplasms; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 70-kDa; RNA, Messenger; Signal Transduction; TOR Serine-Threonine Kinases; Triterpenes; Tumor Cells, Cultured

2014
New composites of betulin esters with arabinogalactan as highly potent anti-cancer agents.
    Natural product research, 2016, Volume: 30, Issue:12

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Esters; Galactans; Humans; Lung Neoplasms; Microscopy, Electron, Scanning; Solubility; Triterpenes

2016
Inhibition of SREBP increases gefitinib sensitivity in non-small cell lung cancer cells.
    Oncotarget, 2016, Aug-09, Volume: 7, Issue:32

    Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; Gefitinib; Humans; Hydroxycholesterols; Lung Neoplasms; Membrane Proteins; Mice; Mice, Nude; Microtubule-Associated Proteins; Protein Kinase Inhibitors; Pyridines; Quinazolines; Signal Transduction; Sterol Regulatory Element Binding Protein 1; Thiazoles; Triterpenes; Xenograft Model Antitumor Assays

2016
Anti-cancer effect of Betulin on a human lung cancer cell line: a pharmacoproteomic approach using 2 D SDS PAGE coupled with nano-HPLC tandem Mass Spectrometry.
    Planta medica, 2009, Volume: 75, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Betula; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cisplatin; Electrophoresis, Polyacrylamide Gel; Flow Cytometry; Humans; Lung Neoplasms; Mass Spectrometry; Phytotherapy; Plant Extracts; Plant Proteins; Proteomics; Tandem Mass Spectrometry; Triterpenes

2009
Synthesis and structure-activity relationship study of cytotoxic germanicane- and lupane-type 3beta-O-monodesmosidic saponins starting from betulin.
    Bioorganic & medicinal chemistry, 2007, Sep-15, Volume: 15, Issue:18

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Betula; Cells, Cultured; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Fibroblasts; Humans; Lung Neoplasms; Molecular Structure; Saponins; Structure-Activity Relationship; Triterpenes

2007