betulin has been researched along with Disease Models, Animal in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 9 (69.23) | 24.3611 |
| 2020's | 3 (23.08) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Wang, L; Zhong, D | 1 |
| Cai, X; Liu, J; Liu, X; Yu, C; Zhu, N | 1 |
| Chen, CS; Chien, SH; Fu, RH; Hung, HS; Lin, SZ; Liu, SP; Shyu, WC; Tsai, CW; Tsai, MC; Tsai, RT | 1 |
| Borkotoky, S; Busi, S; Mohanty, SK; Murali, A; Rajkumari, J; Suchiang, K | 1 |
| Dong, LH; Han, JF; Huang, J; Li, HY; Liu, ZM; Xu, GM; Zan, T; Zhang, HN | 1 |
| Boerries, M; Brandner, JM; Ebeling, S; Merfort, I; Nascimento, JM; Naumann, K; Pollok, S; Schmidt, G; Vidal-Y-Sy, S; Wardecki, T | 1 |
| Cho, N; Jeon, BJ; Kim, HW; Lee, HK; Sung, SH | 1 |
| Han, X; Liu, W; Liu, Z; Zhao, H; Zhao, M | 1 |
| Long, H; Ma, C | 1 |
| Bara, MT; Costa, EA; de Moraes, WF; de Paula, JR; Galdino, PM; Nascimento, MV; Vanderlinde, FA | 1 |
| Ambrus, R; Anghel, M; Bojin, F; Danciu, C; Dehelean, C; Soica, C; Wang, HM; Wenz, G | 1 |
| Varalakshmi, P; Vidya, L | 1 |
13 other study(ies) available for betulin and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Effect of Betulin on Inflammatory Biomarkers and Oxidative Status of Ova-Induced Murine Asthma.
Topics: Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Biomarkers; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Eosinophils; Female; Immunoglobulin E; Lung; Mice; Mice, Inbred BALB C; Ovalbumin; Oxidative Stress; Reactive Oxygen Species; Respiratory Function Tests; Triterpenes | 2020 |
Betulin Alleviates Myocardial Ischemia-Reperfusion Injury in Rats via Regulating the Siti1/NLRP3/NF-κB Signaling Pathway.
Topics: Animals; Anti-Inflammatory Agents; Cytokines; Disease Models, Animal; Heart Rate; Myocardial Reperfusion Injury; Myocytes, Cardiac; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Rats, Wistar; Signal Transduction; Sirtuin 1; Triterpenes; Ventricular Function, Left | 2021 |
Neuroprotective Effects of Betulin in Pharmacological and Transgenic Caenorhabditis elegans Models of Parkinson's Disease.
Topics: Animals; Animals, Genetically Modified; Caenorhabditis elegans; Disease Models, Animal; Dopaminergic Neurons; Nerve Degeneration; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Triterpenes | 2017 |
Attenuation of quorum sensing controlled virulence factors and biofilm formation in Pseudomonas aeruginosa by pentacyclic triterpenes, betulin and betulinic acid.
Topics: Alginates; Animals; Anti-Bacterial Agents; Bacterial Adhesion; Bacterial Proteins; Betulinic Acid; Biofilms; Caenorhabditis elegans; Chitinases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Glucuronic Acid; Glycolipids; Hexuronic Acids; Hydrophobic and Hydrophilic Interactions; Indoles; Metalloendopeptidases; Metalloproteases; Microbial Sensitivity Tests; Microbial Viability; Molecular Docking Simulation; Molecular Dynamics Simulation; Pentacyclic Triterpenes; Polysaccharides, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Pyocyanine; Quorum Sensing; Survival Analysis; Trans-Activators; Triterpenes; Virulence; Virulence Factors | 2018 |
Betulin inhibits lipopolysaccharide/D-galactosamine-induced acute liver injury in mice through activating PPAR-γ.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Galactosamine; Interleukin-1beta; Lipopolysaccharides; Liver; Male; Mice, Inbred BALB C; NF-kappa B; Peroxidase; PPAR gamma; Signal Transduction; Triterpenes; Tumor Necrosis Factor-alpha | 2018 |
From a traditional medicinal plant to a rational drug: understanding the clinically proven wound healing efficacy of birch bark extract.
Topics: Actins; Animals; Betula; Cell Movement; Cell Proliferation; Cyclooxygenase 2; Cytokines; Disease Models, Animal; ELAV Proteins; Gene Expression Regulation; Humans; Inflammation Mediators; Keratinocytes; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Plant Bark; Plant Extracts; Plants, Medicinal; rho GTP-Binding Proteins; RNA Stability; RNA, Messenger; Skin; STAT3 Transcription Factor; Swine; Triterpenes; Wound Healing | 2014 |
Ameliorative effect of betulin from Betula platyphylla bark on scopolamine-induced amnesic mice.
Topics: Administration, Oral; Alzheimer Disease; Amnesia; Animals; Avoidance Learning; Betula; Betulinic Acid; Cognition; Disease Models, Animal; Glutathione; Hippocampus; Humans; Male; Maze Learning; Memory; Mice; Neuroprotective Agents; Nootropic Agents; Pentacyclic Triterpenes; Plant Bark; Plant Extracts; Scopolamine; Triterpenes | 2016 |
Betulin attenuates lung and liver injuries in sepsis.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Betula; Cecum; Cytokines; Disease Models, Animal; HMGB1 Protein; Humans; Inflammation Mediators; Liver; Lung; Male; MAP Kinase Signaling System; NF-kappa B; Plant Bark; Rats; Rats, Sprague-Dawley; Sepsis; Triterpenes | 2016 |
Protective effect of betulin on cognitive decline in streptozotocin (STZ)-induced diabetic rats.
Topics: Animals; Cognitive Dysfunction; Cytokines; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose Tolerance Test; Heme Oxygenase-1; Hippocampus; Male; Malondialdehyde; Maze Learning; NF-E2-Related Factor 2; NF-kappa B; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Triterpenes; Up-Regulation | 2016 |
Triterpenes involved in the anti-inflammatory effect of ethanolic extract of Pterodon emarginatus Vogel stem bark.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Chemical Fractionation; Croton Oil; Disease Models, Animal; Ethanol; Fabaceae; Formaldehyde; Hexanes; Inflammation; Magnetic Resonance Spectroscopy; Male; Methylene Chloride; Mice; Molecular Structure; Pain; Pentacyclic Triterpenes; Plant Bark; Plant Extracts; Plant Stems; Solvents; Triterpenes | 2012 |
Betulin complex in γ-cyclodextrin derivatives: properties and antineoplasic activities in in vitro and in vivo tumor models.
Topics: Animals; Antineoplastic Agents; Calorimetry, Differential Scanning; Caspase 2; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Drug Combinations; Flow Cytometry; gamma-Cyclodextrins; Gene Expression; Immunohistochemistry; Male; Melanoma; Mice; Triterpenes; Tumor Burden; Xenograft Model Antitumor Assays | 2012 |
Control of urinary risk factors of stones by betulin and lupeol in experimental hyperoxaluria.
Topics: Animals; Biomarkers; Calcium Oxalate; Disease Models, Animal; Hyperoxaluria; Male; Pentacyclic Triterpenes; Plant Stems; Plants, Medicinal; Rats; Rats, Wistar; Risk Factors; Triterpenes; Urinary Calculi | 2000 |