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bethanidine and Blood Pressure, High

bethanidine has been researched along with Blood Pressure, High in 39 studies

Bethanidine: A guanidinium antihypertensive agent that acts by blocking adrenergic transmission. The precise mode of action is not clear.

Research Excerpts

ExcerptRelevanceReference
"1 The effects of labetalol, bethanidine and combined treatment with both drugs were compared in a within-patient randomized cross-over study in mild essential hypertension."9.04A comparison and an investigation of a potential synergistic effect of labetalol and bethanidine in patients with mild hypertension. ( Brown, JJ; Chalmers, AG; Hunter, J; Lees, CD; Millar, JA; Robertson, JI, 1979)
"1 The effects of labetalol, bethanidine and combined treatment with both drugs were compared in a within-patient randomized cross-over study in mild essential hypertension."5.04A comparison and an investigation of a potential synergistic effect of labetalol and bethanidine in patients with mild hypertension. ( Brown, JJ; Chalmers, AG; Hunter, J; Lees, CD; Millar, JA; Robertson, JI, 1979)
" The dopamine D2 receptor antagonist, domperidone, caused hypertension in ropinirole-but not vehicle-treated rats."3.69Tolerance to peripheral, but not central, effects of ropinirole, a selective dopamine D2-like receptor agonist. ( Eden, RJ; Parker, SG; Raval, P; Yeulet, S, 1994)
"Symptoms due to orthostatic and exertional hypotension occurred in 23-4 per cent of 448 hypertensive patients treated with guanethidine, debrisoquine, or bethanidine."3.65Factors predisposing to postural hypotensive symptoms in the treatment of high blood pressure. ( Smith, AJ; Talbot, S, 1975)
" The first dose was given 1 h before rising, and the daily dosage was progressively increased."2.64Dihydroergotamine: an effective treatment for postural hypotension due to antihypertensive drugs (ganglion-blocking agents excepted). ( Conté, JJ; Fournié, GJ; Maurette, MH, 1976)
"3."2.64Effect of mianserin hydrochloride on peripheral uptake mechanisms for noradrenaline and 5-hydroxytryptamine in man. ( Coppen, A; Ghose, K; Swade, C; Wood, K, 1978)
"However, a group of subjects with untreated hypertension showed a significantly smaller initial inflow during the suction."1.25The influence of age and the level of arterial blood pressure on the changes in forearm blood flow resulting from sudden alterations in local vascular transmural pressure. ( Fentem, PH; Yates, JM, 1975)
"Hypertension is considered to be the cardiovascular risk factor that is probably most amenable to preventive approaches to public health."1.25Detection, treatment and follow-up of hypertension in a community sample of 55-year-old men. ( Carle, T; Isacsson, SO; Lindell, SE; Malmborg, RO, 1975)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199037 (94.87)18.7374
1990's1 (2.56)18.2507
2000's1 (2.56)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ramanan, SV1
JOHNSTON, AW1
PRICHARD, BN4
ROSENTHEIM, ML1
GIFFORD, RW2
Houston, MC2
Webb, DJ1
Cumming, AM2
Adams, FC1
Hodsman, GP1
Leckie, BJ2
Lever, AF2
Morton, JJ2
Murray, GD1
Robertson, JI3
Zacest, R1
Barrow, CG1
O'Halloran, MW1
Wilson, LL1
Green, AF1
Parker, SG1
Raval, P1
Yeulet, S1
Eden, RJ1
Talbot, S3
Nies, AS1
Israili, ZH1
Wilhelmsen, L1
Berglund, G1
Sannerstedt, R1
Hansson, L1
Andersson, O1
Sievertsson, R1
Wikstrand, J1
Goldberg, AD1
Raftery, EB1
Smith, AJ2
Conté, JJ1
Fournié, GJ1
Maurette, MH1
Ramirez, EA1
Elson, L1
Gear, AS1
Oster, JR1
Talmers, FN1
Thomas, JR1
Rowlands, G2
McConachie, NA2
Currie, WJ2
Coppen, A1
Ghose, K1
Swade, C1
Wood, K1
Burgess, CD1
Turner, P1
Wadsworth, J1
Myers, MG1
Raper, AJ1
Richardson, DW1
Davies, DL1
McElroy, K1
Atkinson, AB1
Brown, JJ2
Fraser, R1
Mackay, A1
Chalmers, AG1
Hunter, J1
Lees, CD1
Millar, JA1
Michael, CA1
Davies, PS1
Boakes, AJ2
Graham, BR1
Proctor, JD1
Evans, EF1
Wasserman, AJ1
Page, LB1
Yager, HM1
Sidd, JJ1
Fentem, PH1
Yates, JM1
O'Malley, BC1
Bing, RH1
Chrysant, SG1
Nishiyama, K1
Adamopoulos, PN1
Frohlich, ED1
Isacsson, SO1
Lindell, SE1
Carle, T1
Malmborg, RO1
Steiner, J1
Cassar, J1
Mashiter, K1
Dawes, I1
Fraser, TR1
Breckenridge, A1

Reviews

4 reviews available for bethanidine and Blood Pressure, High

ArticleYear
Abrupt cessation of treatment in hypertension: consideration of clinical features, mechanisms, prevention and management of the discontinuation syndrome.
    American heart journal, 1981, Volume: 102, Issue:3 Pt 1

    Topics: Acute Disease; Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Bethanidine; Blood Pressure; Cloni

1981
Clinical pharmacology of antihypertensive drugs.
    The Medical clinics of North America, 1977, Volume: 61, Issue:3

    Topics: Adrenergic alpha-Antagonists; Aldosterone; Angiotensin II; Antihypertensive Agents; Bethanidine; Blo

1977
Correlation of pharmacological effects with plasma levels of antihypertensive drugs in man.
    Annual review of pharmacology and toxicology, 1979, Volume: 19

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Bethanidine; Clonidine; Guanethidine; Humans;

1979
New drugs in hypertension.
    Canadian Medical Association journal, 1977, Jan-22, Volume: 116, Issue:2

    Topics: Antihypertensive Agents; Bethanidine; Clonidine; Debrisoquin; Female; Humans; Hypertension; Male; Pr

1977

Trials

14 trials available for bethanidine and Blood Pressure, High

ArticleYear
Relationship of psychological factors to failure of antihypertensive drug treatment.
    Australian and New Zealand journal of medicine, 1981, Volume: 11, Issue:5

    Topics: Adult; Antihypertensive Agents; Bethanidine; Clonidine; Female; Humans; Hypertension; Male; Methyldo

1981
Dihydroergotamine: an effective treatment for postural hypotension due to antihypertensive drugs (ganglion-blocking agents excepted).
    Cardiology, 1976, Volume: 61 suppl 1

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Bethanidine; Blood Pressure; Clinical Trials as To

1976
Multiclinic controlled trial of bethanidine and guanethidine in severe hypertension.
    Circulation, 1977, Volume: 55, Issue:3

    Topics: Bethanidine; Clinical Trials as Topic; Guanethidine; Guanidines; Humans; Hydrochlorothiazide; Hypert

1977
Bethanidine and oxprenolol in hypertension--a study in combination therapy.
    The Practitioner, 1977, Volume: 219, Issue:1309

    Topics: Adolescent; Adult; Aged; Bethanidine; Clinical Trials as Topic; Drug Therapy, Combination; Guanidine

1977
Effect of mianserin hydrochloride on peripheral uptake mechanisms for noradrenaline and 5-hydroxytryptamine in man.
    British journal of clinical pharmacology, 1978, Volume: 5 Suppl 1

    Topics: Antidepressive Agents; Bethanidine; Blood Platelets; Clinical Trials as Topic; Depression; Dibenzaze

1978
Cardiovascular responses to mianserin hydrochloride: a comparison with tricyclic antidepressant drugs.
    British journal of clinical pharmacology, 1978, Volume: 5 Suppl 1

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bethanidine; Blood Pressure; Cardiovascular

1978
Bethanidine vs Guanethidine.
    Circulation, 1978, Volume: 57, Issue:4

    Topics: Bethanidine; Clinical Trials as Topic; Drug Evaluation; Guanethidine; Guanidines; Humans; Hypertensi

1978
A comparison and an investigation of a potential synergistic effect of labetalol and bethanidine in patients with mild hypertension.
    British journal of clinical pharmacology, 1979, Volume: 8, Issue:Suppl 2

    Topics: Adult; Aged; Bethanidine; Blood Pressure; Drug Synergism; Ethanolamines; Female; Guanidines; Heart R

1979
[Dose-effect test of Xipamid in hypertension as compared with other antihypertensive drugs].
    Die Medizinische Welt, 1976, Jun-11, Volume: 27, Issue:24

    Topics: Bethanidine; Blood Pressure; Clinical Trials as Topic; Diuretics; Dose-Response Relationship, Drug;

1976
A within-patient comparison of bethanidine, methyldopa and propranolol in the treatment of hypertension.
    Clinical science and molecular medicine. Supplement, 1976, Volume: 3

    Topics: Bethanidine; Clinical Trials as Topic; Diuretics; Guanidines; Humans; Hypertension; Methyldopa; Phys

1976
Comparison of bethanidine dosing schedules for rapid control of blood pressure.
    Current therapeutic research, clinical and experimental, 1976, Volume: 20, Issue:3

    Topics: Adult; Aged; Bethanidine; Blood Pressure; Dose-Response Relationship, Drug; Drug Administration Sche

1976
Clinical application of new antihypertensive drugs.
    Cleveland Clinic quarterly, 1975,Fall, Volume: 42, Issue:3

    Topics: Antihypertensive Agents; Bethanidine; Clinical Trials as Topic; Diazoxide; Humans; Hypertension; Imi

1975
Letter: Debrisoquine, guanethidine, and bethanidine in hypertension.
    British medical journal, 1975, May-03, Volume: 2, Issue:5965

    Topics: Antihypertensive Agents; Bethanidine; Debrisoquin; Diarrhea; Guanethidine; Guanidines; Humans; Hyper

1975
Effects of methyldopa on prolactin and growth hormone.
    British medical journal, 1976, May-15, Volume: 1, Issue:6019

    Topics: Adult; Bethanidine; Female; Growth Hormone; Humans; Hypertension; Hypoglycemia; Insulin; Male; Methy

1976

Other Studies

21 other studies available for bethanidine and Blood Pressure, High

ArticleYear
The aggressive treatment of hypertension.
    Lancet (London, England), 2003, May-03, Volume: 361, Issue:9368

    Topics: Antihypertensive Agents; Bethanidine; Blood Urea Nitrogen; Drug Administration Schedule; Drug Therap

2003
THE USE OF BETHANIDINE IN THE TREATMENT OF HYPERTENSION.
    Lancet (London, England), 1964, Sep-26, Volume: 2, Issue:7361

    Topics: Bethanidine; Drug Therapy; Ganglionic Blockers; Guanethidine; Guanidines; Humans; Hypertension; Phar

1964
BETHANIDINE SULFATE--A NEW ANTIHYPERTENSIVE AGENT.
    JAMA, 1965, Sep-13, Volume: 193

    Topics: Antihypertensive Agents; Bethanidine; Drug Therapy; Guanethidine; Hypertension; Toxicology

1965
Abrupt discontinuation of antihypertensive therapy.
    Southern medical journal, 1981, Volume: 74, Issue:9

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Bethanidine; Clonidine; Drug Therapy, Combinat

1981
Changes in active and inactive renin and in angiotensin II across the kidney in essential hypertension and renal artery stenosis.
    Journal of hypertension, 1984, Volume: 2, Issue:6

    Topics: Adult; Angiotensin II; Aorta; Bethanidine; Enzyme Activation; Evaluation Studies as Topic; Female; H

1984
The discovery of bretylium and bethanidine.
    British journal of clinical pharmacology, 1982, Volume: 13, Issue:1

    Topics: Animals; Bethanidine; Blood Pressure; Bretylium Compounds; Ganglia, Sympathetic; Guanidines; History

1982
Tolerance to peripheral, but not central, effects of ropinirole, a selective dopamine D2-like receptor agonist.
    European journal of pharmacology, 1994, Nov-14, Volume: 265, Issue:1-2

    Topics: Administration, Oral; Analysis of Variance; Animals; Bethanidine; Blood Pressure; Bromocriptine; Dec

1994
Angina in hypertensive patients. With particular reference to the negative chronotropic effects of sympatholytic therapy.
    Cardiology, 1976, Volume: 61, Issue:4

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Bethanidine; Blood Pressure; Debrisoquin; Drug Therapy

1976
Effect of treatment of hypertension in the primary preventive trial, Göteborg, Sweden.
    British journal of clinical pharmacology, 1979, Volume: 7 Suppl 2

    Topics: Adrenergic beta-Antagonists; Bethanidine; Cardiovascular Diseases; Cerebrovascular Disorders; Corona

1979
Patterns of blood-pressure during chronic administration of postganglionic sympathetic blocking drugs for hypertension.
    Lancet (London, England), 1976, Nov-13, Volume: 2, Issue:7994

    Topics: Adult; Aged; Bethanidine; Blood Pressure; Circadian Rhythm; Debrisoquin; Female; Guanethidine; Guani

1976
Factors predisposing to postural hypotensive symptoms in the treatment of high blood pressure.
    British heart journal, 1975, Volume: 37, Issue:10

    Topics: Bethanidine; Cardiomegaly; Circadian Rhythm; Debrisoquin; Female; Guanethidine; Guanidines; Heart Ra

1975
Management of hypertension.
    The Practitioner, 1975, Volume: 215, Issue:1287

    Topics: Adrenergic beta-Antagonists; Age Factors; Bethanidine; Clonidine; Debrisoquin; Decision Making; Diur

1975
Relationship between exchangeable sodium and blood pressure in different forms of hypertension in man.
    Clinical science (London, England : 1979), 1979, Volume: 57 Suppl 5

    Topics: Adult; Bethanidine; Blood Pressure; Female; Humans; Hyperaldosteronism; Hypertension; Kidney Failure

1979
The treatment of hypertension in pregnancy.
    Australian family physician, 1978, Volume: 7, Issue:9

    Topics: Adolescent; Adult; Anticonvulsants; Antihypertensive Agents; Bethanidine; Eclampsia; Female; Humans;

1978
Sotalol and bethanidine-an open general practice study in the combination therapy of hypertension.
    The British journal of clinical practice, 1977, Volume: 31, Issue:5

    Topics: Adult; Bethanidine; Drug Therapy, Combination; Female; Guanidines; Humans; Hypertension; Male; Middl

1977
Antagonism of bethanidine by mazindol.
    British journal of clinical pharmacology, 1977, Volume: 4, Issue:4

    Topics: Bethanidine; Blood Pressure; Guanidines; Humans; Hypertension; Indoles; Male; Mazindol; Middle Aged;

1977
Drugs in the management of hypertension. Part II.
    American heart journal, 1976, Volume: 92, Issue:1

    Topics: Bethanidine; Guanethidine; Humans; Hypertension; Methyldopa; Secologanin Tryptamine Alkaloids

1976
The combined effect of propranolol with bethanidine or methyldopa in hypertension.
    Advances in clinical pharmacology, 1976, Volume: 11

    Topics: Bethanidine; Blood Pressure; Drug Therapy, Combination; Guanidines; Humans; Hypertension; Methyldopa

1976
The influence of age and the level of arterial blood pressure on the changes in forearm blood flow resulting from sudden alterations in local vascular transmural pressure.
    Cardiovascular research, 1975, Volume: 9, Issue:1

    Topics: Adult; Age Factors; Aged; Atmospheric Pressure; Benzothiadiazines; Bethanidine; Blood Pressure; Diur

1975
Systemic hemodynamic effects of bethanidine in essential hypertension.
    Circulation, 1975, Volume: 52, Issue:1

    Topics: Administration, Oral; Bethanidine; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug;

1975
Detection, treatment and follow-up of hypertension in a community sample of 55-year-old men.
    Scandinavian journal of social medicine, 1975, Volume: 3, Issue:2

    Topics: Anthropometry; Antihypertensive Agents; Bethanidine; Blood Flow Velocity; Blood Pressure; Electrocar

1975