bethanechol has been researched along with Muscle Relaxation in 27 studies
Bethanechol: A slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, HEART RATE changes, and BRONCHIAL SPASM.
bethanechol : The carbamic acid ester of 2-methylcholine. A slowly hydrolysed muscarinic agonist with no nicotinic effects, it is used as its chloride salt to increase smooth muscle tone, as in the gastrointestinal tract following abdominal surgery, treatment of gastro-oesophageal reflux disease, and as an alternative to catheterisation in the treatment of non-obstructive urinary retention.
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We now hypothesize that these impaired relaxation responses are secondary to hyperoxia-induced upregulation of arginase, which competes with NO synthase for L-arginine." | 3.78 | Role of arginase in impairing relaxation of lung parenchyma of hyperoxia-exposed neonatal rats. ( Ali, NK; Jafri, A; Martin, RJ; Prakash, YS; Sopi, RB; Zaidi, SI, 2012) |
| "Nicotine has been shown to reduce both tone and muscular activity in the human colon by releasing nitric oxide (NO) from nerves." | 1.35 | Nicotine-induced neurogenic relaxation in the mouse colon: changes with dextran sodium sulfate-induced colitis. ( Fujino, H; Hamada, Y; Horie, S; Murakami, I; Murayama, T; Yamane, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (29.63) | 18.7374 |
| 1990's | 13 (48.15) | 18.2507 |
| 2000's | 4 (14.81) | 29.6817 |
| 2010's | 2 (7.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Murakami, I | 1 |
| Hamada, Y | 1 |
| Yamane, S | 1 |
| Fujino, H | 1 |
| Horie, S | 1 |
| Murayama, T | 1 |
| Braverman, AS | 1 |
| Vegesna, AK | 1 |
| Miller, LS | 1 |
| Barbe, MF | 1 |
| Tiwana, M | 1 |
| Hussain, K | 1 |
| Ruggieri, MR | 1 |
| Ali, NK | 1 |
| Jafri, A | 1 |
| Sopi, RB | 1 |
| Prakash, YS | 1 |
| Martin, RJ | 1 |
| Zaidi, SI | 1 |
| Bomfim, JH | 1 |
| de Godoy, MA | 1 |
| Giglio, JR | 1 |
| de Oliveira, AM | 1 |
| Arantes, EC | 1 |
| Myung, SC | 1 |
| Oh, SY | 1 |
| Kim, KD | 1 |
| Kim, SC | 1 |
| Lee, MY | 1 |
| Altiere, RJ | 2 |
| Diamond, L | 2 |
| Masuda, Y | 1 |
| Yamahara, NS | 1 |
| Tanaka, M | 1 |
| Ryang, S | 1 |
| Kawai, T | 1 |
| Imaizumi, Y | 1 |
| Watanabe, M | 1 |
| Szarek, JL | 2 |
| Stewart, NL | 1 |
| Spurlock, B | 1 |
| Schneider, C | 1 |
| Koo, HP | 1 |
| Macarak, EJ | 1 |
| Zderic, SA | 1 |
| Duckett, JW | 1 |
| Synder, HM | 1 |
| Levin, RM | 4 |
| Lee, JG | 1 |
| Coplen, D | 1 |
| Macarak, E | 1 |
| Wein, AJ | 2 |
| Cheng, DY | 1 |
| Feng, CJ | 1 |
| Kadowitz, PJ | 1 |
| Gruetter, CA | 1 |
| Itoh, Y | 1 |
| Ando, M | 1 |
| Ohmura, M | 2 |
| Kondo, A | 2 |
| Miyake, K | 1 |
| Saito, M | 2 |
| Wong, KK | 2 |
| Fan, YP | 1 |
| Chakder, S | 1 |
| Rattan, S | 1 |
| Kim, HJ | 1 |
| Sohng, I | 1 |
| Lee, G | 1 |
| Kim, JJ | 1 |
| Koh, SK | 1 |
| Willenbucher, RF | 1 |
| Xie, YN | 1 |
| Eysselein, VE | 1 |
| Snape, WJ | 1 |
| Tzeng, SF | 1 |
| Harrington, SS | 1 |
| Dodds, WJ | 1 |
| Mittal, RK | 1 |
| Spivey, WH | 1 |
| Skobeloff, EM | 1 |
| Kudlacz, EM | 1 |
| Gerald, MC | 1 |
| Wallace, LJ | 1 |
| De Ponti, F | 2 |
| Azpiroz, F | 3 |
| Malagelada, JR | 3 |
| Malkowicz, SB | 1 |
| Atta, MA | 1 |
| Elbadawi, A | 1 |
| Boyer, IJ | 1 |
| DiStefano, V | 1 |
27 other studies available for bethanechol and Muscle Relaxation
| Article | Year |
|---|---|
Nicotine-induced neurogenic relaxation in the mouse colon: changes with dextran sodium sulfate-induced colitis.
Topics: Animals; Atropine; Bethanechol; Colitis, Ulcerative; Colon; Colon, Descending; Colon, Transverse; De | 2009 |
Pharmacologic specificity of nicotinic receptor-mediated relaxation of muscarinic receptor precontracted human gastric clasp and sling muscle fibers within the gastroesophageal junction.
Topics: Adult; Bethanechol; Esophagogastric Junction; Female; Humans; Male; Middle Aged; Muscarinic Agonists | 2011 |
Role of arginase in impairing relaxation of lung parenchyma of hyperoxia-exposed neonatal rats.
Topics: Animals; Animals, Newborn; Arginase; Arginine; Bethanechol; Electric Stimulation; Hyperoxia; Lung; M | 2012 |
Effects induced by Tityus serrulatus scorpion venom and its toxins TsTX-I and TsTX-V on the rat isolated retractor penis muscle.
Topics: Animals; Bethanechol; Biological Assay; Chemical Fractionation; Chromatography, High Pressure Liquid | 2005 |
Effects of spermine on the relaxation response of rat detrusor smooth muscles.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Bethanechol; Calcium Channels, L-Type; Dose-Response | 2007 |
Relaxant effects of vasoactive intestinal peptide and bethanechol in cat intrapulmonary artery.
Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Cats; Drug Interactions; Female; In Vitro Tec | 1983 |
Characterization of muscarinic receptors mediating relaxation and contraction in the rat iris dilator muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Alkaloids; Anim | 1995 |
Sensory nerve- and neuropeptide-mediated relaxation responses in airways of Sprague-Dawley rats.
Topics: Animals; Bethanechol; Bronchodilator Agents; Calcitonin Gene-Related Peptide; Capsaicin; Electric St | 1995 |
The ontogeny of bladder function in the fetal calf.
Topics: Adenosine Triphosphate; Animals; Atropine; Bethanechol; Body Weight; Cattle; Electric Stimulation; F | 1995 |
Comparative studies on the ontogeny and autonomic responses of the fetal calf bladder at different stages of development: involvement of nitric oxide on field stimulated relaxation.
Topics: Adenosine Triphosphate; Animals; Arginine; Bethanechol; Bethanechol Compounds; Cattle; Electric Stim | 1994 |
Effects of 17 beta-estradiol on endothelium-dependent relaxation induced by acetylcholine in female rat aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Bethanechol; Bethanechol Compounds; Dose-Response Relations | 1994 |
Effects of luteinizing hormone-releasing hormone (LH-RH) analogue on the function of the isolated rabbit corpus cavernosum.
Topics: Animals; Antineoplastic Agents, Hormonal; Bethanechol; Castration; Leuprolide; Male; Muscle Contract | 1996 |
Drug induced contraction and relaxation in mouse isolated aorta.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta | 1997 |
Inhibitory effect of zinc protoporphyrin IX on lower esophageal sphincter smooth muscle relaxation by vasoactive intestinal polypeptide and other receptor agonists.
Topics: Animals; Bethanechol; Carbon Monoxide; Colforsin; Esophagogastric Junction; Heme Oxygenase (Decycliz | 1998 |
Does potassium induce the release of nitric oxide in the rabbit corpus cavernosum?
Topics: Animals; Bethanechol; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, S | 1998 |
Effects of acetaldehyde on responses of rabbit corpus cavernosal smooth muscle.
Topics: Acetaldehyde; Animals; Bethanechol; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation | 2000 |
Mechanisms of cAMP-mediated relaxation of distal circular muscle in rabbit colon.
Topics: Animals; Bethanechol; Bethanechol Compounds; Chromatography, High Pressure Liquid; Colon; Cyclic AMP | 1992 |
Norepinephrine-induced contractile responses in isolated rat aortae from different duration of diabetes.
Topics: Animals; Aorta, Thoracic; Bethanechol; Bethanechol Compounds; Diabetes Mellitus, Experimental; Dose- | 1992 |
Identification of longitudinal muscle activity in opossum lower esophageal sphincter.
Topics: Animals; Bethanechol; Bethanechol Compounds; Esophagogastric Junction; Male; Muscle Contraction; Mus | 1991 |
Effect of magnesium chloride on rabbit bronchial smooth muscle.
Topics: Animals; Bethanechol; Bethanechol Compounds; Bronchi; Calcium Chloride; Electric Stimulation; Histam | 1990 |
Effects of diabetes and diuresis on contraction and relaxation mechanisms in rat urinary bladder.
Topics: Aminophylline; Animals; Bethanechol; Bethanechol Compounds; Choline O-Acetyltransferase; Diabetes Me | 1989 |
Relaxatory responses of canine proximal stomach to esophageal and duodenal distension. Importance of vagal pathways.
Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Deglutition; Dilatation; Dogs; Duodenum; Esop | 1989 |
The effect of parasympathetic decentralization on the feline urinary bladder.
Topics: Animals; Bethanechol; Bethanechol Compounds; Cats; Dose-Response Relationship, Drug; In Vitro Techni | 1985 |
Neurally mediated nonadrenergic relaxation in cat airways occurs independent of cholinergic mechanisms.
Topics: Acetylcholine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Bronchi; Cats; Electric Stimul | 1985 |
An investigation of the mechanism of lead-induced relaxation of pigeon crop smooth muscle.
Topics: Adenylyl Cyclases; Animals; Bethanechol; Bethanechol Compounds; Calcium; Columbidae; Crop, Avian; In | 1985 |
Reflex gastric relaxation in response to distention of the duodenum.
Topics: Animals; Bethanechol; Bethanechol Compounds; Body Temperature; Dogs; Duodenum; Muscle Contraction; M | 1987 |
Importance of vagal input in maintaining gastric tone in the dog.
Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Cold Temperature; Dogs; Epinephrine; Fasting; | 1987 |