Page last updated: 2024-10-23

bethanechol and Muscle Contraction

bethanechol has been researched along with Muscle Contraction in 206 studies

Bethanechol: A slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, HEART RATE changes, and BRONCHIAL SPASM.
bethanechol : The carbamic acid ester of 2-methylcholine. A slowly hydrolysed muscarinic agonist with no nicotinic effects, it is used as its chloride salt to increase smooth muscle tone, as in the gastrointestinal tract following abdominal surgery, treatment of gastro-oesophageal reflux disease, and as an alternative to catheterisation in the treatment of non-obstructive urinary retention.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"Bethanechol induced smooth muscle contractions via muscarinic receptor subtype M3."3.74Corticotropin-releasing factor inhibition of sheep fetal colonic contractility: mechanisms to prevent meconium passage in utero. ( Ahanya, SA; Lakshmanan, J; Liu, G; Mazdak, M; Oyachi, N; Ross, MG, 2007)
"Ethanol did not affect resting tension but acetaldehyde and ethanol suppressed bladder muscle contractions."3.70Effects of ethanol and its metabolite acetaldehyde on responses of the rat bladder. ( Kim, HJ; Lee, G; Lee, HW; Lee, JG; Moon, H; Sohng, I, 1999)
" Spontaneous and bethanechol-stimulated jejunal circular muscle contractions were measured in an organ bath."3.70Role of inducible nitric oxide synthase in postoperative intestinal smooth muscle dysfunction in rodents. ( Bauer, AJ; Billiar, TR; Kalff, JC; Schraut, WH; Simmons, RL, 2000)
" The present study was designed to determine whether there were any differences in the effects of anoxia and extracellular acidosis in response to field stimulation, bethanechol and KCl between mature (8 weeks) and neonatal (3 days) rabbit bladder smooth muscle."3.69Developmental factors in the contractile response of rabbit urinary bladder: effect of anoxia and extracellular acidosis. ( Duckett, JW; Levin, RM; Snyder, HM; Yoon, JY; Zderic, SA, 1995)
"We investigated the effects of epithelium removal and cooling (32 degrees C, 27 degrees C, 22 degrees C) on isolated tracheal smooth muscle contraction induced by bethanechol (BCh), acetylcholine (ACh), histamine (Hist), and KCl in guinea pigs."3.68[Effects of epithelium removal and cooling on tracheal contraction in guinea pigs]. ( Hashimoto, Y; Koga, Y; Saito, S; Satoh, S; Sodeyama, N, 1992)
" Circular colonic smooth muscle strips from patients with ulcerative colitis, acute diverticular disease, or adenocarcinoma were stretched to the optimal length and stimulated with electrical field stimulation (EFS), bethanechol, or increased concentrations of extracellular K+."3.68Defect in colonic smooth muscle contraction in patients with ulcerative colitis. ( Hyman, PE; Snape, WJ; Williams, R, 1991)
" The smooth muscle contractions were blocked by atropine, and enhanced by physostigmine, which proves the cholinergic nature of the innervation."3.68Motor response to electric spatial stimulation of isolated intact and inflamed human appendix. ( Antal, A; Bartho, L; Szolcsányi, J, 1991)
" To determine whether the cardiovascular responses evoked by bradykinin were caused by smooth muscle contraction, we compared the increases in gastric smooth muscle tension and blood pressure elicited by bradykinin, bethanechol, or acetylcholine."3.67Chemically induced cardiovascular reflexes arising from the stomach of the cat. ( Longhurst, JC; Ordway, GA; Stebbins, CL, 1984)
"The effect of racemic bethanechol and its (R)- and (S)-enantiomers on smooth muscle contraction and outflow of [3H]-acetylcholine were studied in the guinea-pig myenteric plexus-longitudinal muscle preparation that had been preincubated with [3H]-choline."3.67The effects of racemic bethanechol and its (R)- and (S)-enantiomers on pre- and postjunctional muscarine receptors in the guinea-pig ileum. ( Kilbinger, H; Lambrecht, G; Mutschler, E; Schwörer, H, 1985)
"The effect of neurotensin on smooth muscle contraction was compared in strips from rabbit proximal and distal circular colonic muscle."3.67Calcium dependence of neurotensin stimulation of circular colonic muscle of the rabbit. ( Hyman, PE; Kao, HW; Mayer, EA; Root, D; Sevy, N; Snape, WJ, 1987)
" The decrease in muscle contraction was observed with bethanechol stimulation or electrical field stimulation."3.67Role of inflammatory mediators in colonic smooth muscle function in ulcerative colitis. ( Kao, HW; Snape, WJ, 1988)
"Bladder outlet obstruction secondary to benign prostatic hyperplasia induces numerous changes in bladder morphology, physiology, and pharmacology."2.38Effect of bladder outlet obstruction on the morphology, physiology, and pharmacology of the bladder. ( Kato, K; Levin, RM; Longhurst, PA; Monson, FC; Wein, AJ, 1990)
"We used a model of bladder outlet obstruction in male guinea pigs as a way to produce detrusor overactivity."1.42Conscious voiding during bladder obstruction in guinea pigs correlates with contractile activity of isolated bladders. ( Brookes, S; Costa, M; Gibbins, I; Keightley, L; Nicholas, S; Zagorodnyuk, V, 2015)
"Patients with systemic sclerosis (SSc) have impairments in gastrointestinal smooth muscle function."1.38Effects of scleroderma antibodies and pooled human immunoglobulin on anal sphincter and colonic smooth muscle function. ( Cohen, S; Dimarino, AJ; Jimenez, SA; Mehendiratta, V; Mendoza, F; Rattan, S; Singh, J, 2012)
"Ghrelin, GHRP-6, and capromorelin accelerated gastric emptying in an equipotent manner, with bell-shaped dose-response relationships."1.33Gastric motor effects of peptide and non-peptide ghrelin agonists in mice in vivo and in vitro. ( De Smet, B; Depoortere, I; Kitazawa, T; Peeters, TL; Verbeke, K, 2005)
" Spontaneous contractility and two dose-response curves to the cholinergic agonist bethanechol and adrenergic agonist norepinephrine were quantitated for 6 h."1.32Contractile activity of mouse small intestinal longitudinal smooth muscle. ( Duenes, JA; Kost, LJ; Sarr, MG; Ueno, T, 2004)
" The dose-response curves were shifted to the right by muscarinic antagonists in the following order of affinity: darifenacin (M(3))>methocramine (M(2)) >pirenzepine (M(1))."1.32Mechanisms mediating cholinergic antral circular smooth muscle contraction in rats. ( Ouyang, A; Tandon, T; Wrzos, HF, 2004)
" The dose-response curves to adrenergic agonist norepinephrine did not differ between groups."1.32Effect of ileo-jejunal transposition on ileal longitudinal smooth muscle contractility in vitro in rats. ( Fukushima, K; Funayama, Y; Matsuno, S; Nagao, M; Naito, H; Sasaki, I; Shibata, C; Shiiba, K; Ueno, T; Unno, M, 2004)
" The development of active tension with stretch and the dose-response curve to muscarinic against were significantly increased in the longitudinal muscle of infected animals compared to controls."1.32Effects of intestinal protozoa infection on gastrointestinal transit and contractility in experimental animals. ( Allam, SR; Ibrahim, AM; Nouh, HH, 2004)
"Partial bladder outlet obstruction was surgically induced in twenty New Zealand White rabbits."1.30Metabolic basis for contractile dysfunction following chronic partial bladder outlet obstruction in rabbits. ( Haugaard, N; Levin, RM; Nigro, DA; Wein, AJ, 1999)
" Dose-response experiments to the cholinergic agonist bethanechol (Be, 10(-8)-10(-4) M) were performed in the presence of tetrodotoxin (TTX, 10(-6) M) and to the adrenergic agonist norepinephrine (NE, 10(-8)-10(-4) M) with or without TTX."1.30Adrenergic denervation hypersensitivity in ileal circular smooth muscle after small bowel transplantation in rats. ( Anding, WJ; Balsiger, BM; Sarr, MG; Shibata, C, 1997)
"To determine if Giardia lamblia infection is associated with altered gastrointestinal transit and smooth muscle contractile function, Mongolian gerbils were infected orogastrically with 2 x 10(5) trophozoites (infected) or vehicle (uninfected controls)."1.30Effects of Giardia lamblia infection on gastrointestinal transit and contractility in Mongolian gerbils. ( Deselliers, LP; Olson, ME; Scott, RB; Tan, DT, 1997)
" Dose-response curves of gallbladder strips to cholecystokinin (CCK), bethanechol, and potassium (K+) were constructed in vitro."1.30The basis for progesterone impairment of gallbladder contractility in male guinea pigs in vitro. ( Kiaii, B; Shaffer, EA; Xu, QW, 1998)
"Phentolamine was a significantly more effective inhibitor of the response of the female bladder neck and urethral strips to FS than of the response of the male strips."1.29Comparative pharmacology of the male and female rabbit bladder neck and urethra: involvement of nitric oxide. ( Lee, JG; Levin, RM; Wein, AJ, 1994)
"2) Furosemide-treated rabbits consumed and excreted three times more fluid than did the controls."1.29The effect of furosemide-induced diuresis on rabbit micturition and bladder contractile function. ( Levin, RM; Longhurst, PA; Tammela, TL; Wein, AJ, 1993)
"There is a clear relationship between hyperreflexia and symptoms such as urgency, frequency, nocturia and urinary incontinence."1.29The effect of terodiline on hyperreflexia (in vivo) and the in vitro response of isolated strips of rabbit bladder to field stimulation, bethanechol and KCL. ( Levin, RM; Scheiner, S; Wein, AJ; Zhao, Y, 1993)
"Ischemia was induced by ligation of the bilateral (bilateral ischemia) or right (unilateral ischemia) internal iliac arteries."1.29Effects of Ischemia on the function of the isolated rat detrusor muscle. ( Kondo, A; Miyake, K; Ohmura, M; Saito, M; Yokoi, K, 1996)
"Thapsigargin has been shown to selectively block the sarcoplasmic Ca-ATPase, thereby preventing the reuptake of calcium into intracellular stores and the participation of these calcium storage sites in the contractile response to stimulation."1.29Effect of thapsigargin on the contractile response of the normal and obstructed rabbit urinary bladder. ( Levin, RM; Rohrmann, D; Wein, AJ; Zderic, SA, 1996)
"Bethanechol responses were not affected by SNP."1.29Endogenous NO inhibits NANC but not cholinergic neurotransmission to circular muscle of guinea pig ileum. ( Galligan, JJ; Yunker, AM, 1996)
" The dose-response curves were analyzed for differences in active force development (kg/cm2)."1.29Developmental changes in gastric fundus smooth muscle contractility and involvement of extracellular calcium in fetal and adult guinea pigs. ( Ierardi, JA; Parkman, HP; Paul, DA; Ryan, JP, 1994)
" SP-methylester was markedly less effective than SP and its effects did not fit sigmoid dose-response curves (DRCs)."1.28Modulation of gastric contractions in response to tachykinins and bethanechol by extrinsic nerves. ( Holzer-Petsche, U, 1991)
"Bethanechol has been used to promote bladder emptying although the clinical efficacy of bethanechol remains uncertain."1.28Central actions of bethanechol on the urinary bladder in dogs. ( O'Donnell, PD, 1990)
"(1) Pinacidil is an effective inhibitor of hyperreflexia in the in vivo rabbit model."1.28Effect of pinacidil on spontaneous and evoked contractile activity. ( Hayes, L; Levin, RM; Wein, AJ; Zhao, Y, 1992)
"Substance P was 60-70 times more potent in neonates versus weanlings (p less than 0."1.28Developmental changes in agonist-mediated gastric smooth muscle contraction in the rabbit. ( Hyman, PE; Kimura, S; Snape, WJ; Tomomasa, T; Yagi, H, 1989)
"Studies on the effect of partial bladder outlet obstruction demonstrate that significant alterations in urinary bladder structure and function occur within 24 hours of the creation of the obstruction."1.28Effect of acute complete obstruction on the rabbit urinary bladder. ( Kato, K; Kitada, S; Levin, RM; Wein, AJ, 1989)
"Bethanechol was shown to induce contraction in mouse spleen."1.28Bethanechol induced contraction in mouse spleen. ( Wong, KK, 1990)
"Anoxia was produced by changing the gas mixture to 95% nitrogen, 5% CO2."1.28Effects of anoxia on the biphasic response of isolated strips of rabbit bladder to field stimulation, bethanechol, methoxamine and KCl. ( Bilgen, A; Levin, RM; Wein, AJ; Zhao, Y, 1992)
"Pretreatment with atropine augmented the duration of this relaxation, which could be completely abolished by tetrodotoxin."1.28Differential sensitivities of the sphincter of Oddi and gallbladder to cholecystokinin in the guinea pig: their role in transsphincteric bile flow. ( Bomzon, A; Davison, JS; Harrington, K; Shaffer, EA; Sharkey, KA, 1992)
"Partial bladder outlet obstruction is a commonly encountered pathophysiologic state."1.27Recovery from short-term obstruction of the rabbit urinary bladder. ( Atta, MA; Elbadawi, A; Levin, RM; Malkowicz, SB; Wein, AJ, 1985)
"Metoclopramide was compared with bethanechol chloride and a control substance in a random double blind study."1.27Effects of metoclopramide on detrusor function. ( Mitchell, WC; Venable, DD, 1985)
"Pirenzepine is an antisecretory anticholinergic type drug that has recently been shown to be relatively free of usual anticholinergic side effects on esophageal smooth muscle."1.27Pirenzepine and propantheline effects on esophageal pressure responses to bethanechol. ( Castell, DO; Castell, JA; Dalton, CB; Hassan, M, 1986)
"Smooth muscle contraction is initiated by a rise in intracellular calcium, which binds to calmodulin resulting in myosin phosphorylation."1.27Effect of chlorpromazine (CPZ) on cholecystokinin-induced gallbladder contraction: the role of calcium. ( Davison, JS; Pomeranz, IS; Shaffer, EA, 1988)
" Dose-response curves for ACh-induced increase in isometric tension of tracheal smooth muscle (TSM) showed a leftward shift from control, 2 h after DFP injection."1.27Contractile responses of tracheal smooth muscle in organophosphate-treated swine: 1. Agonist changes. ( Dwyer, TM; Farley, JM; Huang Saunders, HM; Murali Mohan, P; Yang, CM, 1988)

Research

Studies (206)

TimeframeStudies, this research(%)All Research%
pre-199057 (27.67)18.7374
1990's89 (43.20)18.2507
2000's42 (20.39)29.6817
2010's17 (8.25)24.3611
2020's1 (0.49)2.80

Authors

AuthorsStudies
Frara, N1
Barbe, MF4
Giaddui, D1
Braverman, AS6
Amin, M1
Yu, D1
Ruggieri, MR10
Lin, CS1
Wu, TT1
Chang, CH1
Cheng, JT2
Tong, YC3
Nomura, R1
Yanagihara, M1
Sato, H1
Matsumoto, K1
Tashima, K1
Horie, S1
Chen, S1
Fujino, H1
Ueno, K1
Murayama, T1
Miller, LS4
Vegesna, AK4
Martín-Cano, FE1
Camello, PJ1
Pozo, MJ2
Lamarre, NS1
Malykhina, AP1
Wan Saudi, WS1
Halim, MA1
Rudholm-Feldreich, T1
Gillberg, L1
Rosenqvist, E1
Tengholm, A1
Sundbom, M1
Karlbom, U1
Näslund, E1
Webb, DL1
Sjöblom, M1
Hellström, PM1
Nicholas, S1
Keightley, L1
Brookes, S1
Costa, M1
Gibbins, I1
Zagorodnyuk, V1
Chen, JH1
Yang, Z1
Yu, Y1
Huizinga, JD1
Zhang, CH1
Wang, P1
Liu, DH1
Chen, CP1
Zhao, W1
Chen, X1
Chen, C1
He, WQ1
Qiao, YN1
Tao, T1
Sun, J1
Peng, YJ1
Lu, P1
Zheng, K1
Craige, SM1
Lifshitz, LM1
Keaney, JF1
Fogarty, KE1
ZhuGe, R1
Zhu, MS1
Tiwana, MI1
Tallarida, RJ1
Singh, J2
Mehendiratta, V2
Del Galdo, F1
Jimenez, SA2
Cohen, S5
DiMarino, AJ2
Rattan, S2
Ackbar, R1
Malvasio, V1
Holzer, P1
Saxena, AK1
Tiwana, M1
Hussain, K1
Nagao, M2
Duenes, JA3
Sarr, MG7
Zheng, Y2
Chang, S1
Boopathi, E1
Burkett, S1
John, M1
Malkowicz, SB2
Chacko, S2
Zagorodnyuk, VP1
Kyloh, M1
Brookes, SJ1
Nicholas, SJ1
Spencer, NJ1
Mendoza, F1
Kullmann, FA1
Wells, GI1
McKenna, DG1
Thor, KB1
Tada, H1
Nakagawa, K1
Yamamura, T1
Takahashi, T1
Parr, E1
Horowitz, B1
Nelson, MT1
Mawe, GM2
De Wachter, S1
Van Meel, TD1
Wyndaele, JJ1
Nakao, A1
Moore, BA1
Murase, N1
Liu, F1
Zuckerbraun, BS1
Bach, FH1
Choi, AM1
Nalesnik, MA1
Otterbein, LE1
Bauer, AJ6
Oyachi, N3
Lakshmanan, J3
Ahanya, SN1
Bassiri, D1
Atkinson, JB2
Ross, MG3
Balsiger, BM3
Shukla, AR1
Nguyen, T1
Zderic, SA5
DiSanto, M1
Wein, AJ34
Ueno, T2
Kost, LJ1
James, AN1
Ryan, JP3
Crowell, MD1
Parkman, HP7
Wolber, C1
Baur, F1
Fozard, JR1
Wrzos, HF1
Tandon, T1
Ouyang, A4
Shibata, C2
Funayama, Y1
Fukushima, K1
Naito, H1
Unno, M1
Shiiba, K1
Matsuno, S1
Sasaki, I1
Allam, SR1
Nouh, HH1
Ibrahim, AM1
Bomfim, JH1
de Godoy, MA1
Giglio, JR1
de Oliveira, AM1
Arantes, EC1
Shenfeld, OZ2
Meir, KS1
Yutkin, V1
Gofrit, ON1
Landau, EH1
Pode, D1
Ishichi, Y1
Sasaki, M1
Setoh, M1
Tsukamoto, T1
Miwatashi, S1
Nagabukuro, H1
Okanishi, S1
Imai, S1
Saikawa, R1
Doi, T1
Ishihara, Y1
Acosta, R1
Lee, JJ1
Kitazawa, T1
De Smet, B1
Verbeke, K1
Depoortere, I1
Peeters, TL1
Xue, L1
Locke, GR1
Camilleri, M1
Schuurkes, JA1
Meulemans, A1
Coulie, BJ1
Szurszewski, JH2
Farrugia, G1
Otto, B1
Riepl, RL1
Marti, M1
Mevissen, M2
Althaus, H1
Steiner, A2
Murata, P1
Kase, Y1
Tokita, Y1
Takeda, S1
Sasaki, H1
Pfeiffer, JB1
Portier, CJ1
Meylan, M1
Ahanya, SA1
Liu, G1
Mazdak, M1
Myung, SC1
Oh, SY1
Kim, KD1
Kim, SC1
Lee, MY1
Schaefer, N1
Tahara, K1
Websky, MV1
Koscielny, A1
Pantelis, D1
Kalff, JC3
Abu-Elmagd, K1
Hirner, A1
Türler, A1
Snape, WJ12
Mellow, MH1
Light, JK1
Scott, FB1
Hassouna, M1
Abdel-Hakim, A1
Abdel-Rahman, M1
Galeano, C1
Elhilali, MM1
Yamada, K1
Iizuka, M1
Takaiti, O1
Hirning, LD1
Burks, TF2
Re, L1
Cingolani, ML1
Concettoni, C1
Rossini, L1
De Micheli, C1
De Amici, M1
Pratesi, P1
Grana, E1
Santagostino Barbone, MG1
Altiere, RJ1
Diamond, L1
Sogbein, SK1
Downie, JW3
Awad, SA3
Karmazyn, M1
McGuire, EJ2
Savastano, JA1
Levin, RM41
High, J1
Longhurst, JC1
Stebbins, CL1
Ordway, GA2
McDougal, JN1
Miller, MS1
Kreulen, DL1
Del Tacca, M1
Soldani, G1
Bernardini, C1
Martinotti, E1
Saito, M10
Masuda, Y1
Yamahara, NS1
Tanaka, M1
Ryang, S1
Kawai, T1
Imaizumi, Y1
Watanabe, M1
Roelofs, M1
Monson, FC3
Passerini-Glazel, G1
Koteliansky, VE1
Sartore, S1
Yoon, JY1
Duckett, JW3
Snyder, HM2
Reynolds, JC4
Ogorek, CP1
Kreider, MS1
Krasnopolsky, L2
Longhurst, PA10
Koo, HP1
Macarak, EJ1
Synder, HM1
Atta, MA2
Ghoniem, GM1
Paul, DA1
Ierardi, JA1
Broderick, GA1
Wang, MB1
Tammela, TL4
Lee, JG3
Macarak, E1
Coplen, D1
Itoh, H1
Morikawa, A1
Makino, I1
Kiiholma, PJ1
Chancellor, MB2
Briscoe, JA1
Leggett, RE1
Samadzadeh, S2
Behar, J1
Biancani, P1
Scheiner, S1
Zhao, Y4
Hypolite, JA1
Broderick, G1
Packard, D1
Cohen, A1
Haugaard, N4
Murr, MM1
Miller, VM1
Itoh, Y1
Ando, M1
Ohmura, M6
Kondo, A6
Miyake, K2
Kwon, HY2
Parsons, K2
Yokoi, K2
Chin, BC1
Tan, DT3
Scott, RB3
Oliver, MR1
Rohrmann, D1
Cicalese, L2
Halfter, WM2
Heeckt, PF2
Schraut, WH3
Yunker, AM1
Galligan, JJ2
Lu, G1
Mulè, F1
Serio, R1
Langer, JC1
Bramlett, G1
Xu, QW2
Freedman, SM1
Shaffer, EA5
Billiar, TR3
Rao, AS1
Salomons, H1
Keaveny, AP1
Henihan, R1
Offner, G1
Sengupta, A1
Lamorte, WW1
Afdhal, NH1
Yu, HI1
Hung, YC1
Lin, SN1
Kuo, HC1
Eskandari, MK1
Lee, KK1
Anding, WJ2
Morgan, CW1
Ratz, PH2
Deselliers, LP1
Olson, ME1
Schurer, B1
Beger, HG1
Wong, KK3
Kiaii, B1
Kim, HJ3
Moon, H1
Sohng, I2
Lee, HW1
Lee, G3
Trate, DM1
Knight, LC1
Brown, KL1
Maurer, AH1
Fisher, RS1
Nigro, DA1
Bogar, LJ1
Bartula, LL1
Pagano, AP1
Thomas, RM1
Myers, SI1
Simmons, RL1
Kim, JJ1
Koh, SK1
Hand, GA1
Shealy, WD1
Wilson, LB1
Zhao, ZW1
Neff, LJ1
Durstine, JL1
Tao, L1
Huang, Y1
Bourreau, JP1
O'Connor, L1
Buttyan, R1
Das, A1
Dixon, JS1
Gosling, JA1
Lin, AT2
Chen, KK1
Yang, CH1
Chang, LS1
Riedl, CR1
Stephen, RL1
Daha, LK1
Knoll, M1
Plas, E1
Pflüger, H1
Srinivasan, R1
Vela, MF1
Katz, PO1
Tutuian, R1
Castell, JA2
Castell, DO2
Ohtani, N1
Pagala, MK1
Tetsoti, L1
Nagpal, D1
Wise, GJ1
Jezior, JR1
Brady, JD1
Rosenstein, DI1
McCammon, KA1
Miner, AS1
Muinuddin, A1
Xue, S1
Diamant, NE1
Buranakarl, C1
Kijtawornrat, A1
Angkanaporn, K1
Komolvanich, S1
Bovee, KC1
Kim, DH1
Lee, SJ1
Yoon, DK1
Cho, JH1
Tzeng, SF1
Katsuragi, T4
Soejima, O2
Tokunaga, T3
Furukawa, T4
Bomzon, A2
Lax, H1
Davison, JS4
Batra, AK1
Hanno, PM1
Bilgen, A2
Morrison, KJ1
Vanhoutte, PM1
Hayes, L1
Kaplan, SA1
Blaivas, JG1
Hypolite, J1
Koga, Y2
Satoh, S2
Sodeyama, N2
Hashimoto, Y2
Yanagisawa, T1
Hirshman, CA1
Saito, S1
Harrington, K1
Sharkey, KA1
Helm, JF1
Bro, SL1
Dodds, WJ3
Sarna, SK1
Hoffmann, RG1
Arndorfer, RC1
Ogawa, S1
Sato, C1
Harrington, SS1
Mittal, RK1
Williams, R1
Hyman, PE7
Antal, A1
Szolcsányi, J1
Bartho, L1
Kaschube, M1
Brasch, H1
Kato, K5
Usune, S1
Yagi, H2
Holzer-Petsche, U1
O'Donnell, PD1
Elbadawi, A2
Barocelli, E1
Morini, G1
Ballabeni, V1
Lavezzo, A1
Impicciatore, M1
Spivey, WH1
Skobeloff, EM1
Bertiger, G2
Tomomasa, T3
Kimura, S1
Kitada, S2
Chun, AL2
Wallace, LJ3
Gerald, MC3
Ruzich, JV1
Kudlacz, EM1
Kogan, BA1
Iwamoto, HS1
Chun, A1
Monson, F1
Gill, HS2
Whitmore, KE1
Kenakin, TP1
Beek, D1
Finkbeiner, AE1
Mitchell, WC1
Venable, DD1
el-Salmy, S1
Yoo, S1
Gilbert, RJ1
Schwörer, H1
Lambrecht, G1
Mutschler, E1
Kilbinger, H1
Hassan, M1
Dalton, CB1
Esbenshade, TA1
Kolta, MG1
Harada, T1
Micheletti, R2
Montagna, E1
Giachetti, A2
De Ponti, F1
Azpiroz, F1
Malagelada, JR1
Tan, ST1
Kao, HW5
Butler, GB1
Adler, KB1
Evans, JN1
Morgan, DW1
Szarek, JL1
Zorn, SH1
Duman, RS1
Giraldo, E1
Krogsgaard-Larsen, P1
Enna, SJ1
Mayer, EA1
Sevy, N2
Root, D1
Ringer, MJ1
Hsu, CT2
Jing, J1
Kachur, JF1
Allbee, WE1
Gaginella, TS1
Garrick, T1
Mulvihill, S1
Buack, S1
Maeda-Hagiwara, M1
Tache, Y1
Pomeranz, IS1
Murali Mohan, P1
Huang Saunders, HM1
Yang, CM1
Dwyer, TM1
Farley, JM1
Finn, SE1
Mathison, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Precision Medicine in Systemic Sclerosis Gastrointestinal Disease: Evaluating Imaging and Stool Biomarkers for Differentiating Disease Stages and Treatment Responses[NCT04630782]70 participants (Anticipated)Observational2020-04-09Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for bethanechol and Muscle Contraction

ArticleYear
Effect of bladder outlet obstruction on the morphology, physiology, and pharmacology of the bladder.
    The Prostate. Supplement, 1990, Volume: 3

    Topics: Animals; Bethanechol; Bethanechol Compounds; Male; Models, Biological; Muscle Contraction; Pressure;

1990
Is bethanechol chloride clinically effective in promoting bladder emptying? A literature review.
    The Journal of urology, 1985, Volume: 134, Issue:3

    Topics: Animals; Bethanechol; Bethanechol Compounds; Clinical Trials as Topic; Female; Humans; Male; Muscle

1985

Trials

4 trials available for bethanechol and Muscle Contraction

ArticleYear
Cholinergic effects on human gastric motility.
    Gut, 1999, Volume: 45, Issue:3

    Topics: Adult; Atropine; Bethanechol; Duodenum; Electrophysiology; Gastric Emptying; Humans; Male; Manometry

1999
Electromotive administration of intravesical bethanechol and the clinical impact on acontractile detrusor management: introduction of a new test.
    The Journal of urology, 2000, Volume: 164, Issue:6

    Topics: Administration, Intravesical; Administration, Oral; Adult; Aged; Aged, 80 and over; Bethanechol; Ele

2000
Esophageal function testing using multichannel intraluminal impedance.
    American journal of physiology. Gastrointestinal and liver physiology, 2001, Volume: 280, Issue:3

    Topics: Adult; Bethanechol; Catheterization; Deglutition; Electric Impedance; Electrophysiology; Esophagus;

2001
Is bethanechol chloride clinically effective in promoting bladder emptying? A literature review.
    The Journal of urology, 1985, Volume: 134, Issue:3

    Topics: Animals; Bethanechol; Bethanechol Compounds; Clinical Trials as Topic; Female; Humans; Male; Muscle

1985

Other Studies

201 other studies available for bethanechol and Muscle Contraction

ArticleYear
Dog and human bladders have different neurogenic and nicotinic responses in inner versus outer detrusor muscle layers.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2022, 10-01, Volume: 323, Issue:4

    Topics: Animals; Bethanechol; Dogs; Electric Stimulation; Humans; Muscarinic Agonists; Muscle Contraction; M

2022
Changes of Bladder M
    Lower urinary tract symptoms, 2018, Volume: 10, Issue:3

    Topics: Acetylcholine; Animals; Bethanechol; Cholinergic Agonists; Dietary Fats; Feeding Behavior; Male; Mus

2018
Bee venom phospholipase A2-induced phasic contractions in mouse rectum: independent roles of eicosanoid and gap junction proteins and their loss in experimental colitis.
    European journal of pharmacology, 2013, Oct-15, Volume: 718, Issue:1-3

    Topics: Animals; Bee Venoms; Bethanechol; Carbenoxolone; Colitis; Connexin 43; Dextran Sulfate; Eicosanoids;

2013
Enhanced nicotinic receptor mediated relaxations in gastroesophageal muscle fibers from Barrett's esophagus patients.
    Neurogastroenterology and motility, 2014, Volume: 26, Issue:3

    Topics: Adult; Barrett Esophagus; Bethanechol; Carbachol; Cholinergic Agonists; Esophagus; Female; Humans; M

2014
Characterization of the motor inhibitory role of colonic mucosa under chemical stimulation in mice.
    American journal of physiology. Gastrointestinal and liver physiology, 2014, Apr-01, Volume: 306, Issue:7

    Topics: Animals; Bethanechol; Carbon Monoxide; Colon; Enzyme Inhibitors; Female; Gasotransmitters; Gastroint

2014
Nicotinic receptor subtypes mediating relaxation of the normal human clasp and sling fibers of the upper gastric sphincter.
    Neurogastroenterology and motility, 2014, Volume: 26, Issue:7

    Topics: Adult; Bethanechol; Carbachol; Esophageal Sphincter, Lower; Female; Gastric Mucosa; Humans; Male; Mi

2014
Alterations in nerve-evoked bladder contractions in a coronavirus-induced mouse model of multiple sclerosis.
    PloS one, 2014, Volume: 9, Issue:10

    Topics: Adenosine Triphosphate; Animals; Atropine; Bethanechol; Coronavirus; Disease Models, Animal; Mice; M

2014
Neuropeptide S inhibits gastrointestinal motility and increases mucosal permeability through nitric oxide.
    American journal of physiology. Gastrointestinal and liver physiology, 2015, Oct-15, Volume: 309, Issue:8

    Topics: Adult; Animals; Bethanechol; Biomarkers; Gastrointestinal Motility; Gene Expression Regulation; Huma

2015
Conscious voiding during bladder obstruction in guinea pigs correlates with contractile activity of isolated bladders.
    Autonomic neuroscience : basic & clinical, 2015, Volume: 193

    Topics: Animals; Bethanechol; Cholinesterase Inhibitors; Consciousness; Disease Models, Animal; Dose-Respons

2015
Haustral boundary contractions in the proximal 3-taeniated rabbit colon.
    American journal of physiology. Gastrointestinal and liver physiology, 2016, Feb-01, Volume: 310, Issue:3

    Topics: Animals; Bethanechol; Biological Clocks; Colon; Electrophysiological Phenomena; Female; Gastrointest

2016
The molecular basis of the genesis of basal tone in internal anal sphincter.
    Nature communications, 2016, Apr-22, Volume: 7

    Topics: Anal Canal; Animals; Anoctamin-1; Bethanechol; Calcium; Calcium Channels, L-Type; Calcium Signaling;

2016
Quantitation of the contractile response mediated by two receptors: M2 and M3 muscarinic receptor-mediated contractions of human gastroesophageal smooth muscle.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:1

    Topics: Bethanechol; Dose-Response Relationship, Drug; Esophagogastric Junction; Esophagus; Humans; Immunopr

2009
Immunoglobulins from scleroderma patients inhibit the muscarinic receptor activation in internal anal sphincter smooth muscle cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 297, Issue:6

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Anal Canal; Animals; Autoantibodies; Benz

2009
In vitro effect of bethanechol and suberyldicholine on regions of guinea pig esophagus.
    The Journal of surgical research, 2012, May-01, Volume: 174, Issue:1

    Topics: Animals; Bethanechol; Choline; Dose-Response Relationship, Drug; Esophagus; Female; Guinea Pigs; Mal

2012
Pharmacologic specificity of nicotinic receptor-mediated relaxation of muscarinic receptor precontracted human gastric clasp and sling muscle fibers within the gastroesophageal junction.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 338, Issue:1

    Topics: Adult; Bethanechol; Esophagogastric Junction; Female; Humans; Male; Middle Aged; Muscarinic Agonists

2011
Role of hydrogen sulfide as a gasotransmitter in modulating contractile activity of circular muscle of rat jejunum.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2012, Volume: 16, Issue:2

    Topics: Animals; Bethanechol; Cysteine; Dose-Response Relationship, Drug; Gastrointestinal Motility; Hydroge

2012
Generation of a human urinary bladder smooth muscle cell line.
    In vitro cellular & developmental biology. Animal, 2012, Volume: 48, Issue:2

    Topics: Bethanechol; Cell Culture Techniques; Cell Line; Humans; Muscle Contraction; Muscle Proteins; Myocyt

2012
Firing patterns and functional roles of different classes of spinal afferents in rectal nerves during colonic migrating motor complexes in mouse colon.
    American journal of physiology. Gastrointestinal and liver physiology, 2012, Aug-01, Volume: 303, Issue:3

    Topics: Animals; Bethanechol; Colon; Dimethylphenylpiperazinium Iodide; Female; In Vitro Techniques; Male; M

2012
Effects of scleroderma antibodies and pooled human immunoglobulin on anal sphincter and colonic smooth muscle function.
    Gastroenterology, 2012, Volume: 143, Issue:5

    Topics: Acetylcholine; Anal Canal; Animals; Autoantibodies; Bethanechol; Colon; Female; Humans; Immunoglobul

2012
Exogenous activation of muscarinic receptors decreases subsequent non-muscarinic bladder contractions in vivo in the female rat.
    Life sciences, 2013, Apr-09, Volume: 92, Issue:12

    Topics: Acetylcholine; Animals; Atropine; Bethanechol; Cholinesterase Inhibitors; Female; Muscarinic Agonist

2013
Antagonistic effects of CompB on orphanin FQ-induced colonic contractions in rats.
    European journal of pharmacology, 2002, Nov-01, Volume: 454, Issue:1

    Topics: Animals; Benzimidazoles; Bethanechol; Colon; Dose-Response Relationship, Drug; Dynorphins; Electric

2002
ERG K+ channels modulate the electrical and contractile activities of gallbladder smooth muscle.
    American journal of physiology. Gastrointestinal and liver physiology, 2003, Volume: 284, Issue:3

    Topics: Action Potentials; Animals; Bethanechol; Electrophysiology; ERG1 Potassium Channel; Ether-A-Go-Go Po

2003
Study of the afferent nervous system and its evaluation in women with impaired detrusor contractility treated with bethanechol.
    Urology, 2003, Volume: 62, Issue:1

    Topics: Adult; Afferent Pathways; Aged; Bethanechol; Cholinergic Agents; Female; Humans; Middle Aged; Muscle

2003
Immunomodulatory effects of inhaled carbon monoxide on rat syngeneic small bowel graft motility.
    Gut, 2003, Volume: 52, Issue:9

    Topics: Animals; Bethanechol; Blotting, Northern; Carbon Monoxide; Cyclooxygenase 2; Cytokines; Gastrointest

2003
Development of ovine fetal ileal motility: role of muscarinic receptor subtypes.
    American journal of obstetrics and gynecology, 2003, Volume: 189, Issue:4

    Topics: Animals; Atropine; Bethanechol; Female; Fetus; Gastrointestinal Motility; Ileum; Immunohistochemistr

2003
Chronic extrinsic denervation of the small bowel: effect on adrenergic and cholinergic contractile mechanisms in canine ileal circular muscle.
    Surgery, 2003, Volume: 134, Issue:5

    Topics: Acetylcholine; Animals; Bethanechol; Denervation; Dogs; Dose-Response Relationship, Drug; Female; Il

2003
Over expression of smooth muscle specific caldesmon by transfection and intermittent agonist induced contraction alters cellular morphology and restores differentiated smooth muscle phenotype.
    The Journal of urology, 2004, Volume: 171, Issue:5

    Topics: Bethanechol; Calmodulin-Binding Proteins; Cells, Cultured; Gene Expression Regulation; Humans; Muscl

2004
Contractile activity of mouse small intestinal longitudinal smooth muscle.
    The Journal of surgical research, 2004, May-15, Volume: 118, Issue:2

    Topics: Adrenergic Agonists; Animals; Bethanechol; Cholinergic Agonists; Gastrointestinal Motility; Ileum; J

2004
Regional gastric contractility alterations in a diabetic gastroparesis mouse model: effects of cholinergic and serotoninergic stimulation.
    American journal of physiology. Gastrointestinal and liver physiology, 2004, Volume: 287, Issue:3

    Topics: Animals; Bethanechol; Cholinergic Agonists; Diabetes Mellitus, Experimental; Dose-Response Relations

2004
Interaction between adenosine and allergen or compound 48/80 on lung parenchymal strips from actively sensitized Brown Norway rats.
    European journal of pharmacology, 2004, Sep-13, Volume: 498, Issue:1-3

    Topics: Adenosine; Animals; Benzopyrans; Bethanechol; Dogs; Drug Interactions; In Vitro Techniques; Lung; Ma

2004
Mechanisms mediating cholinergic antral circular smooth muscle contraction in rats.
    World journal of gastroenterology, 2004, Nov-15, Volume: 10, Issue:22

    Topics: Anesthetics, Local; Animals; Benzofurans; Bethanechol; Calcium; Calcium Channel Blockers; Cholinergi

2004
Effect of ileo-jejunal transposition on ileal longitudinal smooth muscle contractility in vitro in rats.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2004, Volume: 8, Issue:8

    Topics: Anastomosis, Surgical; Animals; Bethanechol; Electric Stimulation; Ileum; In Vitro Techniques; Jejun

2004
Effects of intestinal protozoa infection on gastrointestinal transit and contractility in experimental animals.
    Journal of the Egyptian Society of Parasitology, 2004, Volume: 34, Issue:3

    Topics: Animals; Bethanechol; Eukaryota; Gastrointestinal Diseases; Gastrointestinal Transit; In Vitro Techn

2004
Effects induced by Tityus serrulatus scorpion venom and its toxins TsTX-I and TsTX-V on the rat isolated retractor penis muscle.
    Pharmacology, 2005, Volume: 73, Issue:4

    Topics: Animals; Bethanechol; Biological Assay; Chemical Fractionation; Chromatography, High Pressure Liquid

2005
Do atherosclerosis and chronic bladder ischemia really play a role in detrusor dysfunction of old age?
    Urology, 2005, Volume: 65, Issue:1

    Topics: Aging; Animals; Aorta, Abdominal; Aortic Diseases; Apolipoproteins E; Arteriosclerosis; Bethanechol;

2005
Novel acetylcholinesterase inhibitor as increasing agent on rhythmic bladder contractions: SAR of 8-{3-[1-(3-fluorobenzyl)piperidin-4-yl]propanoyl}-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one (TAK-802) and related compounds.
    Bioorganic & medicinal chemistry, 2005, Mar-15, Volume: 13, Issue:6

    Topics: Acetylcholinesterase; Animals; Bethanechol; Cholinesterase Inhibitors; Guinea Pigs; Inhibitory Conce

2005
Mechanisms of meconium passage: cholinergic stimulation of electromechanical coordination in the fetal colon.
    Journal of the Society for Gynecologic Investigation, 2005, Volume: 12, Issue:3

    Topics: Animals; Bethanechol; Cholinergic Agents; Colon; Electromyography; Electrophysiology; Female; Gestat

2005
Gastric motor effects of peptide and non-peptide ghrelin agonists in mice in vivo and in vitro.
    Gut, 2005, Volume: 54, Issue:8

    Topics: Animals; Atropine; Bethanechol; Breath Tests; Cholinergic Agents; Dose-Response Relationship, Drug;

2005
Effect of modulation of serotonergic, cholinergic, and nitrergic pathways on murine fundic size and compliance measured by ultrasonomicrometry.
    American journal of physiology. Gastrointestinal and liver physiology, 2006, Volume: 290, Issue:1

    Topics: Animals; Atropine; Bethanechol; Buspirone; Gastric Fundus; Male; Mice; Muscle Contraction; Muscle, S

2006
mu-Opiate receptor agonist loperamide blocks bethanechol-induced gallbladder contraction, despite higher cholecystokinin plasma levels in man.
    Neurogastroenterology and motility, 2005, Volume: 17, Issue:5

    Topics: Adult; Bethanechol; Cholecystokinin; Cross-Over Studies; Gallbladder; Humans; Loperamide; Male; Musc

2005
In vitro effects of bethanechol on equine gastrointestinal contractility and functional characterization of involved muscarinic receptor subtypes.
    Journal of veterinary pharmacology and therapeutics, 2005, Volume: 28, Issue:6

    Topics: Animals; Area Under Curve; Bethanechol; Cecum; Dose-Response Relationship, Drug; Duodenum; Female; G

2005
Intestinal ischemia/reperfusion injury aggravates talc-induced adhesions in rats.
    The Journal of surgical research, 2006, Volume: 135, Issue:1

    Topics: Animals; Bethanechol; Disease Models, Animal; Jejunum; Male; Mesenteric Artery, Superior; Muscle Con

2006
In vitro effects of bethanechol on specimens of intestinal smooth muscle obtained from the duodenum and jejunum of healthy dairy cows.
    American journal of veterinary research, 2007, Volume: 68, Issue:3

    Topics: Animals; Bethanechol; Cattle; Dairying; Dose-Response Relationship, Drug; Duodenum; Female; In Vitro

2007
Corticotropin-releasing factor inhibition of sheep fetal colonic contractility: mechanisms to prevent meconium passage in utero.
    American journal of obstetrics and gynecology, 2007, Volume: 196, Issue:4

    Topics: Animals; Bethanechol; Colon; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fetus

2007
Effects of spermine on the relaxation response of rat detrusor smooth muscles.
    European journal of pharmacology, 2007, Nov-14, Volume: 573, Issue:1-3

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Bethanechol; Calcium Channels, L-Type; Dose-Response

2007
Acute rejection and the muscularis propria after intestinal transplantation: the alloresponse, inflammation, and smooth muscle function.
    Transplantation, 2008, May-27, Volume: 85, Issue:10

    Topics: Acute Disease; Animals; Bethanechol; Graft Rejection; Inflammation; Intestines; Muscle Contraction;

2008
Myoelectric properties of the cat ileocecal sphincter.
    The American journal of physiology, 1981, Volume: 240, Issue:6

    Topics: Action Potentials; Animals; Bethanechol; Bethanechol Compounds; Cats; Cecum; Colon; Electric Conduct

1981
Effect of isosorbide and hydralazine in painful primary esophageal motility disorders.
    Gastroenterology, 1982, Volume: 83, Issue:2

    Topics: Adult; Aged; Bethanechol; Bethanechol Compounds; Deglutition Disorders; Esophageal Diseases; Esophag

1982
Bethanechol chloride and the traumatic cord bladder.
    The Journal of urology, 1982, Volume: 128, Issue:1

    Topics: Adult; Bethanechol; Bethanechol Compounds; Electromyography; Humans; Male; Muscle Contraction; Muscl

1982
Response of the urethral smooth muscles to pharmacological agents. I. Cholinergic and adrenergic agonists and antagonists.
    The Journal of urology, 1983, Volume: 129, Issue:6

    Topics: Animals; Autonomic Agents; Bethanechol; Bethanechol Compounds; Cats; Female; In Vitro Techniques; Is

1983
Effect of trimebutine maleate on bethanechol-induced contractions of gastrointestinal tract in conscious and anaesthetized dogs.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:2

    Topics: Animals; Atropine; Benzoates; Bethanechol; Bethanechol Compounds; Digestive System Physiological Phe

1983
Characterization of motilin induced contractions of the isolated canine intestine.
    Proceedings of the Western Pharmacology Society, 1983, Volume: 26

    Topics: Animals; Bethanechol; Bethanechol Compounds; Dimethylphenylpiperazinium Iodide; Dogs; Drug Interacti

1983
Cholinergic effects of cimetidine and ranitidine.
    Pharmacological research communications, 1983, Volume: 15, Issue:5

    Topics: Acetylcholine; Animals; Anura; Atropine; Bethanechol; Bethanechol Compounds; Cimetidine; Drug Synerg

1983
Relative potencies of the stereoisomers of bethanechol on muscarinic receptor.
    Il Farmaco; edizione scientifica, 1983, Volume: 38, Issue:7

    Topics: Animals; Bethanechol; Bethanechol Compounds; Chemical Phenomena; Chemistry; In Vitro Techniques; Mus

1983
Relaxant effects of vasoactive intestinal peptide and bethanechol in cat intrapulmonary artery.
    European journal of pharmacology, 1983, Sep-16, Volume: 93, Issue:1-2

    Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Cats; Drug Interactions; Female; In Vitro Tec

1983
Urethral response during bladder contraction induced by subcutaneous bethanechol chloride: elicitation of a sympathetic reflex urethral constriction.
    The Journal of urology, 1984, Volume: 131, Issue:4

    Topics: Animals; Bethanechol; Bethanechol Compounds; Cats; Male; Muscle Contraction; Prazosin; Reflex; Sympa

1984
Mechanical trauma to bladder epithelium liberates prostanoids which modulate neurotransmission in rabbit detrusor muscle.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 230, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bethanechol; Bethanechol Compounds; Carbachol; Dose-Response

1984
Urodynamic findings and long-term outcome management of patients with multiple sclerosis-induced lower urinary tract dysfunction.
    The Journal of urology, 1984, Volume: 132, Issue:4

    Topics: Adult; Aged; Bethanechol; Bethanechol Compounds; Female; Humans; Imipramine; Male; Mandelic Acids; M

1984
The effect of short-term obstruction on urinary bladder function in the rabbit.
    The Journal of urology, 1984, Volume: 132, Issue:4

    Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Electric Stimulation; Epinephri

1984
Chemically induced cardiovascular reflexes arising from the stomach of the cat.
    The American journal of physiology, 1984, Volume: 247, Issue:3 Pt 2

    Topics: Acetylcholine; Animals; Bethanechol; Bethanechol Compounds; Blood Pressure; Bradykinin; Capsaicin; C

1984
Age-related changes in colonic function in rats.
    The American journal of physiology, 1984, Volume: 247, Issue:5 Pt 1

    Topics: Aging; Animals; Bethanechol; Bethanechol Compounds; Chromium Radioisotopes; Colon; Electric Stimulat

1984
Comparative study of pA2 values of pirenzepine and atropine for guinea-pig gastric fundus and gastric smooth muscle.
    Pharmacology, 1984, Volume: 29, Issue:6

    Topics: Animals; Atropine; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Female; Gastric Fundus; Ga

1984
Effect of partial outlet obstruction on contractility: comparison between severe and mild obstruction.
    Neurourology and urodynamics, 1993, Volume: 12, Issue:6

    Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Disease Models, Animal; Electri

1993
Characterization of muscarinic receptors mediating relaxation and contraction in the rat iris dilator muscle.
    British journal of pharmacology, 1995, Volume: 114, Issue:4

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Alkaloids; Anim

1995
Contractility and phenotype transitions in serosal thickening of obstructed rabbit bladder.
    Journal of applied physiology (Bethesda, Md. : 1985), 1995, Volume: 78, Issue:4

    Topics: Animals; Bethanechol; Cytoskeletal Proteins; Cytoskeleton; Fluorescent Antibody Technique; Immunohis

1995
Developmental factors in the contractile response of rabbit urinary bladder: effect of anoxia and extracellular acidosis.
    Biology of the neonate, 1995, Volume: 67, Issue:5

    Topics: Acidosis; Animals; Animals, Newborn; Bethanechol; Carbon Dioxide; Electric Stimulation; Hydrogen-Ion

1995
Thyrotropin-releasing hormone: an inhibitory regulatory peptide of feline lower esophageal sphincter.
    The American journal of physiology, 1993, Volume: 264, Issue:3 Pt 1

    Topics: Animals; Bethanechol; Bethanechol Compounds; Bombesin; Cats; Dose-Response Relationship, Drug; Esoph

1993
The role of the mucosa in the in vitro changes in guinea pig bladder function which occur after sensitization with ovalbumin.
    Pharmacology, 1995, Volume: 50, Issue:2

    Topics: Animals; Bethanechol; Electric Stimulation; Female; Guinea Pigs; Histamine; In Vitro Techniques; Muc

1995
The ontogeny of bladder function in the fetal calf.
    The Journal of urology, 1995, Volume: 154, Issue:1

    Topics: Adenosine Triphosphate; Animals; Atropine; Bethanechol; Body Weight; Cattle; Electric Stimulation; F

1995
Effect of mucosal removal on the response of the feline bladder to pharmacological stimulation.
    The Journal of urology, 1995, Volume: 153, Issue:4

    Topics: Adenosine Triphosphate; Animals; Bethanechol; Cats; Electric Stimulation; Female; In Vitro Technique

1995
Developmental changes in gastric fundus smooth muscle contractility and involvement of extracellular calcium in fetal and adult guinea pigs.
    Pediatric research, 1994, Volume: 36, Issue:5

    Topics: Acetylcholine; Animals; Bethanechol; Calcium; Embryonic and Fetal Development; Female; Gastric Fundu

1994
Effect of chronic ethanol consumption on the pharmacological response of the rabbit corpus cavernosum.
    Pharmacology, 1994, Volume: 49, Issue:6

    Topics: Alcoholism; Animals; Bethanechol; Ethanol; In Vitro Techniques; Male; Muscle Contraction; Muscle, Sm

1994
Decreased electromechanical activity of guinea pig circular muscle during pregnancy.
    Gastroenterology, 1993, Volume: 105, Issue:5

    Topics: Animals; Bethanechol; Bethanechol Compounds; Female; Guinea Pigs; In Vitro Techniques; Muscle Contra

1993
Temporal changes in rabbit urinary bladder function and DNA synthesis during chronic treatment with furosemide.
    The Journal of urology, 1994, Volume: 151, Issue:2

    Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Cell Division; Diuresis; DNA; E

1994
Distribution and function of the adrenergic and cholinergic receptors in the fetal calf bladder during mid-gestational age.
    Neurourology and urodynamics, 1993, Volume: 12, Issue:6

    Topics: Animals; Bethanechol; Bethanechol Compounds; Cattle; Electric Stimulation; Fetus; Gestational Age; I

1993
Comparative pharmacology of the male and female rabbit bladder neck and urethra: involvement of nitric oxide.
    Pharmacology, 1994, Volume: 48, Issue:4

    Topics: Animals; Arginine; Atropine; Bethanechol; Bethanechol Compounds; Electric Stimulation; Female; In Vi

1994
Urinary bladder dysfunction in spontaneously diabetic Chinese hamsters.
    Diabetes research and clinical practice, 1994, Volume: 22, Issue:2-3

    Topics: Acetylcholinesterase; Aging; Animals; Bethanechol; Bethanechol Compounds; Blood Glucose; Cricetinae;

1994
Effects of atropine, glucagon, and bethanechol on urodynamics of continent cecal urinary reservoir before and after complete, partial, and sham detubularizations in dog.
    Neurourology and urodynamics, 1993, Volume: 12, Issue:1

    Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Cecum; Dogs; Glucagon; Male; Muscle Contracti

1993
The effect of furosemide-induced diuresis on rabbit micturition and bladder contractile function.
    The Journal of urology, 1993, Volume: 150, Issue:1

    Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Citrate (si)-Synthase; Diuresis

1993
The influence of diabetes mellitus on glucose utilization by the rat urinary bladder.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:6

    Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Body Weight; Chromatography, Hi

1993
Pathogenesis of simultaneous esophageal contractions in patients with motility disorders.
    Gastroenterology, 1993, Volume: 105, Issue:1

    Topics: Atropine; Bethanechol; Bethanechol Compounds; Deglutition; Deglutition Disorders; Esophageal Motilit

1993
The effect of terodiline on hyperreflexia (in vivo) and the in vitro response of isolated strips of rabbit bladder to field stimulation, bethanechol and KCL.
    Pharmacology, 1993, Volume: 46, Issue:6

    Topics: Animals; Bethanechol; Bethanechol Compounds; Butylamines; Drug Interactions; Electric Stimulation; M

1993
Correlation of contractile function of the rabbit corpus cavernosum with NADH fluorescence.
    Pharmacology, 1993, Volume: 46, Issue:6

    Topics: Animals; Bethanechol; Bethanechol Compounds; Fluorescence; Isoproterenol; Male; Methoxamine; Muscle

1993
Effect of partial outlet obstruction on choline acetyltransferase activity in the rat and rabbit.
    Neurourology and urodynamics, 1993, Volume: 12, Issue:3

    Topics: Animals; Bethanechol; Bethanechol Compounds; Choline O-Acetyltransferase; Electric Stimulation; In V

1993
Effects of partial outlet obstruction of the rat urinary bladder on micturition characteristics, DNA synthesis and the contractile response to field stimulation and pharmacological agents.
    The Journal of urology, 1993, Volume: 150, Issue:3

    Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Circadian Rhythm; DNA; Electric

1993
Contractile properties of enteric smooth muscle after small bowel transplantation in rats.
    American journal of surgery, 1996, Volume: 171, Issue:1

    Topics: Animals; Bethanechol; In Vitro Techniques; Intestine, Small; Jejunum; Muscle Contraction; Muscle, Sm

1996
Effects of luteinizing hormone-releasing hormone (LH-RH) analogue on the function of the isolated rabbit corpus cavernosum.
    Hinyokika kiyo. Acta urologica Japonica, 1996, Volume: 42, Issue:3

    Topics: Animals; Antineoplastic Agents, Hormonal; Bethanechol; Castration; Leuprolide; Male; Muscle Contract

1996
Effects of glucose deprivation on the contractile response of the rabbit bladder to repetitive stimulation.
    Neurourology and urodynamics, 1996, Volume: 15, Issue:1

    Topics: Animals; Bethanechol; Electric Stimulation; Glucose; In Vitro Techniques; Male; Muscarinic Agonists;

1996
Effects of Ischemia on the function of the isolated rat detrusor muscle.
    Hinyokika kiyo. Acta urologica Japonica, 1996, Volume: 42, Issue:2

    Topics: Adenosine Triphosphate; Animals; Bethanechol; Electric Stimulation; In Vitro Techniques; Ischemia; M

1996
Effects of long-term partial outflow obstruction on bladder function in the rat.
    Neurourology and urodynamics, 1996, Volume: 15, Issue:2

    Topics: Animals; Bethanechol; Follow-Up Studies; Male; Muscle Contraction; Organ Size; Potassium Chloride; R

1996
Effects of partial outlet obstruction on bladder-strip sensitivity to glucose deprivation: an in vitro study in the rat.
    World journal of urology, 1996, Volume: 14 Suppl 1

    Topics: Analysis of Variance; Animals; Bethanechol; Electric Stimulation; Glucose; In Vitro Techniques; Male

1996
Massive intestinal resection depresses circular smooth muscle contractility in the rat.
    Canadian journal of physiology and pharmacology, 1995, Volume: 73, Issue:10

    Topics: Animals; Bethanechol; Colon; Decerebrate State; Female; Gastrointestinal Transit; Ileum; Jejunum; Ma

1995
Colonic motor response to IgE-mediated mast cell degranulation in the Hooded-Lister rat.
    Neurogastroenterology and motility, 1996, Volume: 8, Issue:2

    Topics: Albumins; Animals; Bethanechol; Colon; Immunoglobulin E; Mast Cells; Motor Activity; Muscle Contract

1996
Effect of thapsigargin on the contractile response of the normal and obstructed rabbit urinary bladder.
    Pharmacology, 1996, Volume: 52, Issue:2

    Topics: Animals; Bethanechol; Calcium-Transporting ATPases; Electric Stimulation; Enzyme Inhibitors; In Vitr

1996
Immunocyte infiltration of the graft muscularis and its effect on muscle function during acute rejection of rat small intestinal allografts.
    Transplantation proceedings, 1996, Volume: 28, Issue:5

    Topics: Animals; Bethanechol; Electric Stimulation; Graft Rejection; Intestine, Small; Jejunum; Macrophages;

1996
Endogenous NO inhibits NANC but not cholinergic neurotransmission to circular muscle of guinea pig ileum.
    The American journal of physiology, 1996, Volume: 271, Issue:5 Pt 1

    Topics: Acetylcholine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; Bethanechol; Biphenyl Compo

1996
Effect of extrinsic denervation in a canine model of jejunoileal autotransplantation on mechanical and electrical activity of jejunal circular smooth muscle.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:1

    Topics: Animals; Bethanechol; Denervation; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Fem

1997
Mode and mechanism of neurotensin action in rat proximal colon.
    European journal of pharmacology, 1997, Jan-29, Volume: 319, Issue:2-3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1997
Effect of prokinetic agents on ileal contractility in a rabbit model of gastroschisis.
    Journal of pediatric surgery, 1997, Volume: 32, Issue:4

    Topics: Abdominal Muscles; Animals; Animals, Newborn; Bethanechol; Cisapride; Congenital Abnormalities; Eryt

1997
Inhibitory effect of bile salts on gallbladder smooth muscle contractility in the guinea pig in vitro.
    Gastroenterology, 1997, Volume: 112, Issue:5

    Topics: Animals; Bethanechol; Bile Acids and Salts; Cholecystokinin; Electric Stimulation; Gallbladder; Guin

1997
Interaction between ischemia/reperfusion-induced leukocyte emigration and translocating bacterial enterotoxins on enteric muscle function.
    Transplantation proceedings, 1997, Volume: 29, Issue:3

    Topics: Animals; Bethanechol; Chemotaxis, Leukocyte; Enterobacter; Enterococcus; Escherichia coli; In Vitro

1997
Nitric oxide and gallbladder motility in prairie dogs.
    The American journal of physiology, 1997, Volume: 272, Issue:4 Pt 1

    Topics: Animals; Bethanechol; Blotting, Western; Cholecystokinin; Dose-Response Relationship, Drug; Enzyme I

1997
Contractile responses and calcium mobilization induced by muscarinic agonists in the rat urinary bladder: effects of age.
    General pharmacology, 1997, Volume: 28, Issue:4

    Topics: Age Factors; Animals; Bethanechol; Calcium; Fura-2; In Vitro Techniques; Male; Muscarinic Agonists;

1997
Effects of alterations in potassium and calcium concentrations on the pressure generated in rat whole bladder in vitro.
    International journal of urology : official journal of the Japanese Urological Association, 1996, Volume: 3, Issue:6

    Topics: Animals; Bethanechol; Calcium; Cholinergic Fibers; Dose-Response Relationship, Drug; Electric Stimul

1996
Pharmacological characterization of the muscarinic receptor subtypes responsible for the contractile response in the rat urinary bladder.
    Journal of autonomic pharmacology, 1997, Volume: 17, Issue:1

    Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Analysis of Var

1997
Comparative study of the effects of capsaicin on the contractility of normal and spinal cord injured human bladders.
    Proceedings of the National Science Council, Republic of China. Part B, Life sciences, 1997, Volume: 21, Issue:1

    Topics: Analgesics; Bethanechol; Capsaicin; Electric Stimulation; Humans; In Vitro Techniques; Muscarinic Ag

1997
Effect of ischemia and partial outflow obstruction on rat bladder function.
    Urological research, 1997, Volume: 25, Issue:3

    Topics: Animals; Bethanechol; Ischemia; Male; Muscle Contraction; Organ Size; Parasympathomimetics; Rats; Ra

1997
Effects of ethanol on responses of isolated rabbit urinary bladder and urethra.
    International journal of urology : official journal of the Japanese Urological Association, 1997, Volume: 4, Issue:3

    Topics: Adenosine Triphosphate; Animals; Bethanechol; Central Nervous System Depressants; Dose-Response Rela

1997
Lipopolysaccharide activates the muscularis macrophage network and suppresses circular smooth muscle activity.
    The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 1

    Topics: Animals; Bethanechol; DNA Primers; Electric Conductivity; Endotoxemia; Jejunum; Leukocytes; Lipopoly

1997
Adrenergic denervation hypersensitivity in ileal circular smooth muscle after small bowel transplantation in rats.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:11

    Topics: Adrenergic Agonists; Adrenergic Fibers; Animals; Bethanechol; Cholinergic Agonists; Dose-Response Re

1997
Bethanechol activates a post-receptor negative feedback mechanism in rabbit urinary bladder smooth muscle.
    The Journal of urology, 1998, Volume: 159, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1998
Effects of Giardia lamblia infection on gastrointestinal transit and contractility in Mongolian gerbils.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:12

    Topics: Animals; Bethanechol; Gastrointestinal Motility; Gastrointestinal Transit; Gerbillinae; Giardiasis;

1997
Heterotopic intestinal transplantation aggravates the insult of chronic rejection.
    Transplantation, 1998, Feb-15, Volume: 65, Issue:3

    Topics: Animals; Bethanechol; Electrophysiology; Graft Rejection; In Vitro Techniques; Intestinal Mucosa; In

1998
Drug induced contraction and relaxation in mouse isolated aorta.
    Artery, 1997, Volume: 22, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta

1997
The basis for progesterone impairment of gallbladder contractility in male guinea pigs in vitro.
    The Journal of surgical research, 1998, Volume: 79, Issue:2

    Topics: Animals; Bethanechol; Calcimycin; Cholecystokinin; Dose-Response Relationship, Drug; Enzyme Inhibito

1998
Effects of ethanol and its metabolite acetaldehyde on responses of the rat bladder.
    BJU international, 1999, Volume: 83, Issue:6

    Topics: Acetaldehyde; Adenosine Triphosphate; Animals; Bethanechol; Central Nervous System Depressants; Dose

1999
Metabolic basis for contractile dysfunction following chronic partial bladder outlet obstruction in rabbits.
    Molecular and cellular biochemistry, 1999, Volume: 200, Issue:1-2

    Topics: Animals; Bethanechol; Citrate (si)-Synthase; Electric Stimulation; In Vitro Techniques; Muscle Contr

1999
Effect of experimental acalculous cholecystitis on gallbladder smooth muscle contractility.
    Digestive diseases and sciences, 1999, Volume: 44, Issue:11

    Topics: Animals; Bethanechol; Cholecystitis; Common Bile Duct; Gallbladder; Gallbladder Emptying; Guinea Pig

1999
Role of inducible nitric oxide synthase in postoperative intestinal smooth muscle dysfunction in rodents.
    Gastroenterology, 2000, Volume: 118, Issue:2

    Topics: Animals; Bethanechol; Enzyme Inhibitors; In Vitro Techniques; Intestine, Small; Lysine; Male; Mice;

2000
Effects of acetaldehyde on responses of rabbit corpus cavernosal smooth muscle.
    Journal of Korean medical science, 2000, Volume: 15, Issue:3

    Topics: Acetaldehyde; Animals; Bethanechol; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation

2000
Spinal cholinergic inhibition of the pressor response to muscle activation is mediated by muscarinic, but not nicotinic, receptors.
    Brain research, 2000, Sep-22, Volume: 877, Issue:2

    Topics: Acetylcholine; Afferent Pathways; Animals; Atropine; Bethanechol; Blood Pressure; Cats; Dose-Respons

2000
Control of the mode of excitation-contraction coupling by Ca(2+) stores in bovine trachealis muscle.
    American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 279, Issue:4

    Topics: Animals; Bethanechol; Calcium; Calcium Channel Blockers; Cattle; Charybdotoxin; In Vitro Techniques;

2000
Obstructive response of human bladder to BPH vs. rabbit bladder response to partial outlet obstruction: a direct comparison.
    Neurourology and urodynamics, 2000, Volume: 19, Issue:5

    Topics: Adaptation, Physiological; Animals; Bethanechol; Calcium Signaling; Calcium-Transporting ATPases; Ca

2000
Mannitol facilitates rabbit urinary bladder recovery from overdistension injury.
    Urology, 2000, Oct-01, Volume: 56, Issue:4

    Topics: Adenosine Triphosphate; Animals; Bethanechol; Energy Metabolism; Lipid Peroxidation; Male; Malondial

2000
Chronic extrinsic denervation after small bowel transplantation in rat jejunum: Effects and adaptation in nitrergic and non-nitrergic neuromuscular inhibitory mechanisms.
    Surgery, 2001, Volume: 129, Issue:4

    Topics: Adaptation, Physiological; Adrenergic alpha-Agonists; Animals; Bethanechol; Cholinergic Agonists; De

2001
Aging effects on contractility of longitudinal and circular detrusor and trigone of rat bladder.
    The Journal of urology, 2001, Volume: 166, Issue:2

    Topics: Aging; Animals; Bethanechol; Collagen; Electric Stimulation; In Vitro Techniques; Male; Muscarinic A

2001
Dependency of detrusor contractions on calcium sensitization and calcium entry through LOE-908-sensitive channels.
    British journal of pharmacology, 2001, Volume: 134, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetamides; Amides; Animals; Bethanechol; Calcium; Ca

2001
Regional differences in the response of feline esophageal smooth muscle to stretch and cholinergic stimulation.
    American journal of physiology. Gastrointestinal and liver physiology, 2001, Volume: 281, Issue:6

    Topics: Animals; Bethanechol; Biomechanical Phenomena; Cats; Cholinergic Agents; Electric Stimulation; Esoph

2001
Effects of bethanechol on canine urinary bladder smooth muscle function.
    Research in veterinary science, 2001, Volume: 71, Issue:3

    Topics: Acetylcholine; Animals; Atropine; Bethanechol; Calcium; Calcium Channel Blockers; Culture Techniques

2001
Acute effects of serotonin on rat bladder contractility.
    Urologia internationalis, 2002, Volume: 68, Issue:1

    Topics: Animals; Bethanechol; Dose-Response Relationship, Drug; Electric Stimulation; Male; Models, Animal;

2002
Differential inhibition of cholinergic and noncholinergic neurogenic contractions by 5-hydroxytryptamine1A receptor agonists in guinea pig ileum.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bethanechol; Bethanechol Compounds; Choline; Electr

1992
Norepinephrine-induced contractile responses in isolated rat aortae from different duration of diabetes.
    Artery, 1992, Volume: 19, Issue:1

    Topics: Animals; Aorta, Thoracic; Bethanechol; Bethanechol Compounds; Diabetes Mellitus, Experimental; Dose-

1992
Evidence for postjunctional release of ATP evoked by stimulation of muscarinic receptors in ileal longitudinal muscles of guinea pig.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:3

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Electric Stimula

1992
The source of calcium for CCK-induced contraction of the guinea-pig gall bladder.
    Regulatory peptides, 1992, Jan-02, Volume: 37, Issue:1

    Topics: Animals; Bethanechol; Bethanechol Compounds; Calcium; Gallbladder; Gallopamil; Guinea Pigs; Male; Mu

1992
Detubularization-induced contractile response change of the ileum following ileocystoplasty.
    The Journal of urology, 1992, Volume: 148, Issue:1

    Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Electric Stimulation; Ileum; Is

1992
Effects of anoxia on the biphasic response of isolated strips of rabbit bladder to field stimulation, bethanechol, methoxamine and KCl.
    Pharmacology, 1992, Volume: 44, Issue:5

    Topics: Animals; Bethanechol; Bethanechol Compounds; Electric Stimulation; Hypoxia; Male; Methoxamine; Muscl

1992
Characterization of muscarinic receptors that mediate contraction of guinea-pig isolated trachea to choline esters: effect of removing epithelium.
    British journal of pharmacology, 1992, Volume: 106, Issue:3

    Topics: Acetylcholine; Animals; Bethanechol; Bethanechol Compounds; Carbachol; Dose-Response Relationship, D

1992
Effect of pinacidil on spontaneous and evoked contractile activity.
    Pharmacology, 1992, Volume: 45, Issue:1

    Topics: Animals; Bethanechol; Bethanechol Compounds; Blood Pressure; Guanidines; Kinetics; Male; Methoxamine

1992
The cholinergic and purinergic components of detrusor contractility in a whole rabbit bladder model.
    The Journal of urology, 1992, Volume: 148, Issue:3

    Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Dose-Response Relationship, Dru

1992
Influence of the bathing medium on the contractile responses of the rabbit urinary bladder.
    Pharmacology, 1992, Volume: 45, Issue:2

    Topics: Animals; Bethanechol; Bethanechol Compounds; Electric Stimulation; Isotonic Solutions; Male; Muscle

1992
Energetics of muscarinic stimulation of smooth muscle.
    Advances in experimental medicine and biology, 1992, Volume: 311

    Topics: Animals; Bethanechol; Bethanechol Compounds; Calcium; Diltiazem; In Vitro Techniques; Kinetics; Musc

1992
Role of acetylcholinesterase in airway epithelium-mediated inhibition of acetylcholine-induced contraction of guinea-pig isolated trachea.
    European journal of pharmacology, 1992, Sep-22, Volume: 220, Issue:2-3

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Bethanechol; Bethanechol Compounds; Dose-Response Rela

1992
[Effects of epithelium removal and cooling on tracheal contraction in guinea pigs].
    Masui. The Japanese journal of anesthesiology, 1992, Volume: 41, Issue:10

    Topics: Acetylcholine; Animals; Bethanechol; Bethanechol Compounds; Epithelium; Guinea Pigs; Histamine; In V

1992
Differential sensitivities of the sphincter of Oddi and gallbladder to cholecystokinin in the guinea pig: their role in transsphincteric bile flow.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:10

    Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Bile; Cholecystokinin; Electric Stimulation;

1992
Myogenic oscillatory mechanism for opossum esophageal smooth muscle contractions.
    The American journal of physiology, 1991, Volume: 261, Issue:3 Pt 1

    Topics: Animals; Bethanechol; Bethanechol Compounds; In Vitro Techniques; Muscle Contraction; Muscle, Smooth

1991
Existence of ATP-evoked ATP release system in smooth muscles.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:2

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Firefly Luciferi

1991
Identification of longitudinal muscle activity in opossum lower esophageal sphincter.
    The American journal of physiology, 1991, Volume: 261, Issue:6 Pt 1

    Topics: Animals; Bethanechol; Bethanechol Compounds; Esophagogastric Junction; Male; Muscle Contraction; Mus

1991
Defect in colonic smooth muscle contraction in patients with ulcerative colitis.
    The American journal of physiology, 1991, Volume: 261, Issue:6 Pt 1

    Topics: Adenocarcinoma; Adult; Bethanechol; Bethanechol Compounds; Colitis, Ulcerative; Colon; Colonic Neopl

1991
Effect of anoxia on in vitro bladder function.
    Pharmacology, 1991, Volume: 43, Issue:6

    Topics: Animals; Bethanechol; Bethanechol Compounds; In Vitro Techniques; Male; Muscle Contraction; Oxygen;

1991
Motor response to electric spatial stimulation of isolated intact and inflamed human appendix.
    Acta chirurgica Hungarica, 1991, Volume: 32, Issue:1

    Topics: Appendicitis; Appendix; Atropine; Bethanechol; Bethanechol Compounds; Electric Stimulation; Gastroin

1991
Pre- and postjunctional effects of phorbol 12-myristate-13-acetate in the mouse vas deferens.
    European journal of pharmacology, 1991, Oct-29, Volume: 204, Issue:1

    Topics: Animals; Bethanechol; Bethanechol Compounds; Calcium Chloride; Electric Stimulation; In Vitro Techni

1991
Somatostatin selectively inhibits excitatory contractile pathways of the feline lower esophageal sphincter.
    Regulatory peptides, 1990, Mar-05, Volume: 27, Issue:3

    Topics: Animals; Bethanechol; Bethanechol Compounds; Bombesin; Cats; Electromyography; Esophagogastric Junct

1990
A possible coupling of postjunctional ATP release and transmitters' receptor stimulation in smooth muscles.
    Life sciences, 1990, Volume: 46, Issue:18

    Topics: Acetylcholine; Adenosine Triphosphate; Animals; Atropine; Bethanechol; Bethanechol Compounds; Bradyk

1990
Development factors in the contractile response of the rabbit bladder to both autonomic and non-autonomic agents.
    Pharmacology, 1990, Volume: 41, Issue:3

    Topics: Adenosine Triphosphate; Age Factors; Animals; Animals, Newborn; Bethanechol; Bethanechol Compounds;

1990
Developmental changes in agonist-mediated colonic smooth muscle contraction in the rabbit.
    Pediatric research, 1991, Volume: 29, Issue:1

    Topics: Animals; Animals, Newborn; Atropine; Bethanechol; Bethanechol Compounds; Colon; In Vitro Techniques;

1991
Modulation of gastric contractions in response to tachykinins and bethanechol by extrinsic nerves.
    British journal of pharmacology, 1991, Volume: 103, Issue:4

    Topics: Animals; Bethanechol; Bethanechol Compounds; Dose-Response Relationship, Drug; Female; Male; Muscle

1991
Central actions of bethanechol on the urinary bladder in dogs.
    The Journal of urology, 1990, Volume: 143, Issue:3

    Topics: Animals; Bethanechol; Bethanechol Compounds; Dogs; Electromyography; Muscle Contraction; Pressure; U

1990
Comparative physiology and pharmacology of the cat and rabbit urinary bladder.
    The Journal of urology, 1990, Volume: 143, Issue:4

    Topics: Adenosine Triphosphate; Animals; Atropine; Bethanechol; Bethanechol Compounds; Cats; Electric Stimul

1990
Effects of two new pirenzepine analogs on the contractile response of the guinea-pig oesophageal muscularis mucosae to acetylcholine, bethanechol, histamine and high potassium.
    European journal of pharmacology, 1990, Apr-10, Volume: 179, Issue:1-2

    Topics: Acetylcholine; Animals; Atropine; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Esophagus;

1990
Effect of magnesium chloride on rabbit bronchial smooth muscle.
    Annals of emergency medicine, 1990, Volume: 19, Issue:10

    Topics: Animals; Bethanechol; Bethanechol Compounds; Bronchi; Calcium Chloride; Electric Stimulation; Histam

1990
Bethanechol induced contraction in mouse spleen.
    The Chinese journal of physiology, 1990, Volume: 33, Issue:2

    Topics: Animals; Bethanechol; Bethanechol Compounds; Clonidine; In Vitro Techniques; Mice; Muscle Contractio

1990
Properties of the feline pyloric sphincter in vitro.
    Gastroenterology, 1987, Volume: 92, Issue:6

    Topics: Action Potentials; Animals; Bethanechol; Bethanechol Compounds; Cats; Duodenum; Electric Stimulation

1987
Developmental changes in agonist-mediated gastric smooth muscle contraction in the rabbit.
    Pediatric research, 1989, Volume: 26, Issue:5

    Topics: Animals; Animals, Newborn; Bethanechol; Bethanechol Compounds; Bombesin; In Vitro Techniques; Muscle

1989
Effect of acute complete obstruction on the rabbit urinary bladder.
    The Journal of urology, 1989, Volume: 141, Issue:1

    Topics: Animals; Bethanechol; Bethanechol Compounds; Electric Stimulation; Hexamethonium; Hexamethonium Comp

1989
Effects of age on urinary bladder function in the male rat.
    The Journal of urology, 1989, Volume: 141, Issue:1

    Topics: Aging; Animals; Bethanechol; Bethanechol Compounds; Isoproterenol; Male; Muscle Contraction; Muscle,

1989
Functional and pharmacological effects of ureteral diversion.
    The Journal of urology, 1989, Volume: 141, Issue:2

    Topics: Animals; Bethanechol; Bethanechol Compounds; Dogs; Electric Stimulation; Male; Methoxamine; Muscle C

1989
Effects of diabetes and diuresis on contraction and relaxation mechanisms in rat urinary bladder.
    Diabetes, 1989, Volume: 38, Issue:3

    Topics: Aminophylline; Animals; Bethanechol; Bethanechol Compounds; Choline O-Acetyltransferase; Diabetes Me

1989
Lower urinary tract function in the sheep fetus: studies of autonomic control and pharmacologic responses of the fetal bladder.
    The Journal of urology, 1989, Volume: 141, Issue:4

    Topics: Animals; Atropine; Autonomic Nervous System; Bethanechol; Bethanechol Compounds; Diltiazem; Female;

1989
In vitro intravesical instillation of anticholinergic, antispasmodic and calcium blocking agents (rabbit whole bladder model).
    The Journal of urology, 1989, Volume: 141, Issue:6

    Topics: Administration, Intravesical; Animals; Atropine; Bethanechol; Bethanechol Compounds; Calcium Channel

1989
Pharmacological responses of rabbit urinary bladder after subtotal cystectomy.
    The Journal of urology, 1989, Volume: 142, Issue:2 Pt 1

    Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Electric Stimulation; Epinephri

1989
Functional and biochemical alterations in the rabbit urinary bladder following ileocystoplasty.
    The Journal of urology, 1989, Volume: 142, Issue:3

    Topics: Animals; Bethanechol; Bethanechol Compounds; Creatine; Electric Stimulation; Ileum; Male; Muscle Con

1989
Self-cancellation of drug properties as a mode of organ selectivity: the antimuscarinic effects of ambenonium.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:3

    Topics: Acetylcholine; Acetylcholinesterase; Ambenonium Chloride; Animals; Bethanechol; Bethanechol Compound

1985
Recovery from short-term obstruction of the rabbit urinary bladder.
    The Journal of urology, 1985, Volume: 134, Issue:2

    Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Isoproterenol; Male; Methoxamin

1985
Clinical use of bethanechol.
    The Journal of urology, 1985, Volume: 134, Issue:3

    Topics: Animals; Bethanechol; Bethanechol Compounds; Cats; Humans; Muscle Contraction; Urinary Bladder; Urin

1985
Effects of metoclopramide on detrusor function.
    The Journal of urology, 1985, Volume: 134, Issue:4

    Topics: Animals; Bethanechol; Bethanechol Compounds; Dogs; Double-Blind Method; Female; Metoclopramide; Musc

1985
Effect of acute selective sacral rhizotomy in cats on bladder and urethral function and the response to bethanechol chloride.
    The Journal of urology, 1985, Volume: 134, Issue:4

    Topics: Animals; Bethanechol; Bethanechol Compounds; Cats; Female; Male; Muscle Contraction; Pressure; Refle

1985
Effect of amino acids on isolated colonic smooth muscle from the rabbit.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3

    Topics: Amino Acids; Animals; Bethanechol; Bethanechol Compounds; Colon; Dose-Response Relationship, Drug; I

1985
Effect of selective muscarinic antagonists on peristaltic contractions in opossum smooth muscle.
    The American journal of physiology, 1986, Volume: 250, Issue:1 Pt 1

    Topics: Animals; Atropine; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Dose-Response Relationship

1986
Functional effects of the purinergic innervation of the rabbit urinary bladder.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:2

    Topics: Adenosine Triphosphate; Animals; Atropine; Bethanechol; Bethanechol Compounds; Dose-Response Relatio

1986
The effects of racemic bethanechol and its (R)- and (S)-enantiomers on pre- and postjunctional muscarine receptors in the guinea-pig ileum.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 331, Issue:4

    Topics: Animals; Bethanechol; Bethanechol Compounds; Cholinesterase Inhibitors; Female; Guinea Pigs; Ileum;

1985
Pirenzepine and propantheline effects on esophageal pressure responses to bethanechol.
    The American journal of gastroenterology, 1986, Volume: 81, Issue:5

    Topics: Adult; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Esophagus; Female; Gastrointestinal Ag

1986
Effect of age on cholinergic muscarinic responsiveness and receptors in the rat urinary bladder.
    The Journal of urology, 1986, Volume: 136, Issue:2

    Topics: Acetylcholine; Aging; Animals; Atropine; Bethanechol; Bethanechol Compounds; Male; Muscle Contractio

1986
Release of acetylcholine mediated by cholecystokinin receptor from the guinea pig sphincter of Oddi.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:2

    Topics: Acetylcholine; Ampulla of Vater; Angiotensin II; Animals; Atropine; Bethanechol; Bethanechol Compoun

1986
AF-DX 116, a cardioselective muscarinic antagonist.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:2

    Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Carbachol; Cats; Dimethylphenylpiperazinium I

1987
Reflex gastric relaxation in response to distention of the duodenum.
    The American journal of physiology, 1987, Volume: 252, Issue:5 Pt 1

    Topics: Animals; Bethanechol; Bethanechol Compounds; Body Temperature; Dogs; Duodenum; Muscle Contraction; M

1987
Effects of bethanechol and the octapeptide of cholecystokinin on colonic smooth muscle in the cat.
    The American journal of physiology, 1987, Volume: 252, Issue:5 Pt 1

    Topics: Animals; Bethanechol; Bethanechol Compounds; Cats; Colon; Electrophysiology; Muscle Contraction; Mus

1987
Modulation of rabbit airway smooth muscle responsiveness by respiratory epithelium. Involvement of an inhibitory metabolite of arachidonic acid.
    The American review of respiratory disease, 1987, Volume: 135, Issue:5

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bethanechol; Bethanechol Compounds; Bronchi; Epitheliu

1987
(R)-nipecotic acid ethyl ester: a direct-acting cholinergic agonist that displays greater efficacy at M2 than at M1 muscarinic receptors.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:1

    Topics: Adenylyl Cyclase Inhibitors; Animals; Bethanechol; Bethanechol Compounds; Binding, Competitive; Carb

1987
Calcium dependence of neurotensin stimulation of circular colonic muscle of the rabbit.
    Gastroenterology, 1987, Volume: 93, Issue:4

    Topics: Animals; Bethanechol; Bethanechol Compounds; Calcium; Colon; Dose-Response Relationship, Drug; In Vi

1987
[3H]QNB binding and contraction of rabbit colonic smooth muscle cells.
    The American journal of physiology, 1987, Volume: 253, Issue:5 Pt 1

    Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Binding, Competitive; Cell Count; Colon; Kine

1987
Effect of bethanechol on glycolysis and high energy phosphate metabolism of the rabbit urinary bladder.
    The Journal of urology, 1988, Volume: 139, Issue:3

    Topics: Adenine; Adenine Nucleotides; Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; E

1988
Role of inflammatory mediators in colonic smooth muscle function in ulcerative colitis.
    Digestive diseases and sciences, 1988, Volume: 33, Issue:3 Suppl

    Topics: Animals; Bethanechol; Bethanechol Compounds; Colitis, Ulcerative; Colon; Electric Stimulation; Gastr

1988
Evidence for a direct and indirect action of leucine enkephalin at the feline ileocecal sphincter.
    Life sciences, 1988, Volume: 42, Issue:18

    Topics: Action Potentials; Animals; Bethanechol; Bethanechol Compounds; Cats; Electric Stimulation; Enkephal

1988
Development of the muscarinic receptor in rabbit gastric smooth muscle.
    The American journal of physiology, 1988, Volume: 254, Issue:5 Pt 1

    Topics: Animals; Animals, Newborn; Atropine; Bethanechol; Bethanechol Compounds; Dose-Response Relationship,

1988
Antihistaminic and antimuscarinic effects of amitriptyline on guinea pig ileal electrolyte transport and muscle contractility in vitro.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:2

    Topics: Amitriptyline; Animals; Bethanechol; Bethanechol Compounds; Electrolytes; Guinea Pigs; Histamine H1

1988
Intracerebroventricular pressure inhibits gastric antral and duodenal contractility but not acid secretion in conscious rabbits.
    Gastroenterology, 1988, Volume: 95, Issue:1

    Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Cerebral Ventricles; Duodenum; Gastric Juice;

1988
Sources of calcium for contraction of distal circular muscle or taenia coli in the rabbit.
    The American journal of physiology, 1988, Volume: 254, Issue:6 Pt 1

    Topics: Animals; Bethanechol; Bethanechol Compounds; Caffeine; Calcium; Calmodulin; Colon; Isometric Contrac

1988
Effect of chlorpromazine (CPZ) on cholecystokinin-induced gallbladder contraction: the role of calcium.
    Israel journal of medical sciences, 1988, Volume: 24, Issue:6

    Topics: Animals; Bethanechol; Bethanechol Compounds; Calcium; Chlorpromazine; Cholecystokinin; Dose-Response

1988
Contractile responses of tracheal smooth muscle in organophosphate-treated swine: 1. Agonist changes.
    Journal of autonomic pharmacology, 1988, Volume: 8, Issue:2

    Topics: Acetylcholine; Animals; Bethanechol; Bethanechol Compounds; Cholinesterases; Dose-Response Relations

1988
Effect of prostaglandin E2 on rabbit colonic smooth muscle cell contraction.
    The American journal of physiology, 1988, Volume: 255, Issue:6 Pt 1

    Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Colon; Cyclic AMP; Dinoprostone; In Vitro Tec

1988
Modified smooth muscle responses of jejunum in streptozotocin-diabetic rats.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:3

    Topics: Animals; Bethanechol; Bethanechol Compounds; Bradykinin; Diabetes Mellitus, Experimental; Jejunum; M

1988