bethanechol has been researched along with Gastroesophageal Reflux in 31 studies
Bethanechol: A slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, HEART RATE changes, and BRONCHIAL SPASM.
bethanechol : The carbamic acid ester of 2-methylcholine. A slowly hydrolysed muscarinic agonist with no nicotinic effects, it is used as its chloride salt to increase smooth muscle tone, as in the gastrointestinal tract following abdominal surgery, treatment of gastro-oesophageal reflux disease, and as an alternative to catheterisation in the treatment of non-obstructive urinary retention.
Gastroesophageal Reflux: Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the efficacy of bethanechol in the treatment of gastroesophageal reflux with that of antiacids, a prospective, cross-over study was undertaken, in which 20 affected infants and children were randomized into two groups on 6-week alternate bethanechol and antiacids oral medication." | 9.05 | Bethanechol versus antiacids in the treatment of gastroesophageal reflux. ( Ansaldi, N; Dell'Olio, D; Giuliani, L; Guardamagna, O; Levi, P; Marmo, F; Mostert, M; Ponzone, A; Saluzzo, C, 1985) |
| "Lower esophageal sphincter (LES) pressure, as well as esophageal peristaltic amplitude, duration, and velocity were measured in 16 infants with gastroesophageal reflux before administration of subcutaneous bethanechol, and at 10, 20, and 30 min after." | 7.67 | Early effects of bethanechol on the esophageal motor function of infants with gastroesophageal reflux. ( Arnold, GL; Sondheimer, JM, 1986) |
| " To determine if bethanechol stimulation would increase the diagnostic yield, we examined 87 patients with chest pain but no gastroesophageal reflux, 47 patients with gastroesophageal reflux but no chest pain, and 20 normal subjects." | 7.67 | Bethanechol increases the diagnostic yield in patients with esophageal chest pain. ( Huber, T; Nostrant, TT; Sams, J, 1986) |
| "Bethanechol did not increase gastric emptying." | 6.65 | Effects of metoclopramide and bethanechol on delayed gastric emptying present in gastroesophageal reflux patients. ( Berkowitz, DM; Fink, SM; Lerner, E; McCallum, RW, 1983) |
| "In infants with a clinical presentation suggestive of chronic GER-related cough, the use of omeprazole and bethanacol appears to be viable therapeutic option." | 5.16 | [A pilot trial on the treatment of gastroesophageal reflux-related cough in infants]. ( Adamko, DJ; Jones, AB; Majaesic, CM; Skappak, C, 2012) |
| "To compare the efficacy of bethanechol in the treatment of gastroesophageal reflux with that of antiacids, a prospective, cross-over study was undertaken, in which 20 affected infants and children were randomized into two groups on 6-week alternate bethanechol and antiacids oral medication." | 5.05 | Bethanechol versus antiacids in the treatment of gastroesophageal reflux. ( Ansaldi, N; Dell'Olio, D; Giuliani, L; Guardamagna, O; Levi, P; Marmo, F; Mostert, M; Ponzone, A; Saluzzo, C, 1985) |
| "The author discusses the role of prokinetic agents, such as bethanechol, metoclopramide, domperidone, and cisipride in the management of gastroesophageal reflux disease." | 4.78 | Gastric emptying in gastroesophageal reflux and the therapeutic role of prokinetic agents. ( McCallum, RW, 1990) |
| " To determine if bethanechol stimulation would increase the diagnostic yield, we examined 87 patients with chest pain but no gastroesophageal reflux, 47 patients with gastroesophageal reflux but no chest pain, and 20 normal subjects." | 3.67 | Bethanechol increases the diagnostic yield in patients with esophageal chest pain. ( Huber, T; Nostrant, TT; Sams, J, 1986) |
| "Bethanechol is a direct agonist of the acetylcholine receptor that was recently introduced in the therapy of gastro-oesophageal reflux." | 3.67 | Acute dystonic reaction to bethanechol--a direct acetylcholine receptor agonist. ( Beharab, A; Levy, Y; Nitzam, M; Shafrir, Y; Steinherz, R, 1986) |
| " This formulation appears to be clinically acceptable and provides a convenient dosage form for use in pediatric patients." | 2.68 | Bethanechol chloride oral solutions: stability and use in infants. ( Saulnier, JL; Schlatter, JL, 1997) |
| "Depending on the severity of the GERD manifestation, pharmacotherapy is often added." | 2.41 | Management of supraesophageal complications of gastroesophageal reflux disease in infants and children. ( Orenstein, SR, 2000) |
| "The esophageal pH probe identifies gastroesophageal reflux." | 2.38 | Chronic pulmonary aspiration in children. ( Bauer, ML; Figueroa-Colon, R; Georgeson, K; Young, DW, 1993) |
| "Indications for the studies were upper airway obstruction (UAO) and congenital choanal atresia (CCA)." | 1.29 | Proximal pH-metry for diagnosis of upper airway complications of gastroesophageal reflux. ( Beste, DJ; Conley, SF; Werlin, SL, 1995) |
| "Gastroesophageal reflux (GER) during infancy is a disorder of unknown etiology which may be associated with abnormalities of upper gastrointestinal motor function." | 1.27 | Effect of bethanechol and metoclopramide on upper gastrointestinal motility in the kitten. ( Gryboski, J; Hillemeier, C; McCallum, R; Oertel, R, 1986) |
| "Gastroesophageal reflux (GER) disease is a common, multifactorial medical condition that may be difficult to treat." | 1.27 | A critical review of current medical therapy for gastroesophageal reflux disease. ( Richter, JE, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (51.61) | 18.7374 |
| 1990's | 12 (38.71) | 18.2507 |
| 2000's | 1 (3.23) | 29.6817 |
| 2010's | 2 (6.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gottrand, F | 1 |
| Adamko, DJ | 1 |
| Majaesic, CM | 1 |
| Skappak, C | 1 |
| Jones, AB | 1 |
| Tolia, V | 1 |
| Dubois, RS | 1 |
| Richter, JE | 4 |
| Castell, DO | 1 |
| Hunold, W | 1 |
| McCallum, RW | 3 |
| Fink, SM | 1 |
| Lerner, E | 1 |
| Berkowitz, DM | 1 |
| Shapiro, GG | 1 |
| Christie, DL | 1 |
| Van Renterghem, D | 1 |
| Vermeire, P | 1 |
| Turton, DB | 1 |
| Shakir, KM | 1 |
| Robinson, M | 1 |
| Anselmino, M | 1 |
| Clark, GW | 1 |
| Hinder, RA | 1 |
| Costantini, M | 1 |
| Sturniolo, GC | 1 |
| Zaninotto, G | 1 |
| D'Incà, R | 1 |
| Polo, R | 1 |
| Naccarato, R | 1 |
| Ancona, E | 1 |
| Ramirez, B | 1 |
| Bauer, ML | 1 |
| Figueroa-Colon, R | 1 |
| Georgeson, K | 1 |
| Young, DW | 1 |
| Conley, SF | 1 |
| Werlin, SL | 1 |
| Beste, DJ | 1 |
| Kazi, N | 1 |
| Mobarhan, S | 1 |
| Schlatter, JL | 1 |
| Saulnier, JL | 1 |
| Heading, RC | 1 |
| Baldi, F | 1 |
| Holloway, RH | 1 |
| Janssens, J | 1 |
| Jian, R | 1 |
| Scarpignato, C | 1 |
| Sontag, SJ | 1 |
| Wienbeck, M | 1 |
| Orenstein, SR | 2 |
| Costa, PM | 1 |
| Fernandes, FV | 1 |
| Yang, S | 1 |
| Cannon, RA | 1 |
| Levi, P | 1 |
| Marmo, F | 1 |
| Saluzzo, C | 1 |
| Dell'Olio, D | 1 |
| Ansaldi, N | 1 |
| Giuliani, L | 1 |
| Guardamagna, O | 1 |
| Mostert, M | 1 |
| Ponzone, A | 1 |
| Hillemeier, C | 1 |
| McCallum, R | 1 |
| Oertel, R | 1 |
| Gryboski, J | 1 |
| Sondheimer, JM | 1 |
| Arnold, GL | 1 |
| Spechler, SJ | 1 |
| Goyal, RK | 1 |
| Nostrant, TT | 1 |
| Sams, J | 1 |
| Huber, T | 1 |
| Shafrir, Y | 1 |
| Levy, Y | 1 |
| Beharab, A | 1 |
| Nitzam, M | 1 |
| Steinherz, R | 1 |
| Tytgat, GN | 1 |
| Nio, CY | 1 |
13 reviews available for bethanechol and Gastroesophageal Reflux
| Article | Year |
|---|---|
[Prokinetics in childhood].
Topics: Adolescent; Anti-Ulcer Agents; Antiemetics; Bethanechol; Child; Child, Preschool; Cisapride; Cross-S | 2010 |
Gastroesophageal reflux. Pathogenesis, diagnosis, and therapy.
Topics: Alginates; Antacids; Barium Sulfate; Bethanechol; Bethanechol Compounds; Cimetidine; Esophagitis, Pe | 1982 |
Gastroesophageal reflux and asthma.
Topics: Adolescent; Adult; Aged; Asthma; Bethanechol; Bethanechol Compounds; Child; Child, Preschool; Cimeti | 1983 |
Prokinetic therapy for gastroesophageal reflux disease.
Topics: Bethanechol; Cisapride; Domperidone; Erythromycin; Gastroesophageal Reflux; Humans; Metoclopramide; | 1995 |
Esophageal chest pain: state of the art.
Topics: Bethanechol; Bethanechol Compounds; Calcium Channel Blockers; Chest Pain; Diagnosis, Differential; E | 1993 |
Review article: promotility drugs in the treatment of gastro-oesophageal reflux disease.
Topics: Adult; Benzamides; Bethanechol; Bethanechol Compounds; Child; Cisapride; Erythromycin; Gastroesophag | 1993 |
Chronic pulmonary aspiration in children.
Topics: Bethanechol; Bethanechol Compounds; Bronchoscopy; Child; Chronic Disease; Diet Therapy; Gastric Acid | 1993 |
Enteral feeding associated gastroesophageal reflux and aspiration pneumonia: a review.
Topics: Bethanechol; Cisapride; Enteral Nutrition; Gastroesophageal Reflux; Humans; Nutrition Disorders; Par | 1996 |
Management of supraesophageal complications of gastroesophageal reflux disease in infants and children.
Topics: Bethanechol; Child; Child, Preschool; Cimetidine; Cisapride; Fundoplication; Gastroesophageal Reflux | 2000 |
Controversies in pediatric gastroesophageal reflux.
Topics: Bethanechol; Bethanechol Compounds; Child; Child, Preschool; Diagnosis, Differential; Esophagus; Gas | 1992 |
Gastric emptying in gastroesophageal reflux and the therapeutic role of prokinetic agents.
Topics: Bethanechol; Bethanechol Compounds; Cisapride; Domperidone; Esophagogastric Junction; Gastric Emptyi | 1990 |
Barrett's esophagus.
Topics: Adenocarcinoma; Antacids; Barrett Esophagus; Bethanechol; Bethanechol Compounds; Cimetidine; Epithel | 1986 |
The medical therapy of reflux oesophagitis.
Topics: Antacids; Bethanechol; Bethanechol Compounds; Cimetidine; Cisapride; Domperidone; Esophagitis, Pepti | 1987 |
4 trials available for bethanechol and Gastroesophageal Reflux
| Article | Year |
|---|---|
[A pilot trial on the treatment of gastroesophageal reflux-related cough in infants].
Topics: Bethanechol; Cough; Double-Blind Method; Female; Gastroesophageal Reflux; Humans; Hydrogen-Ion Conce | 2012 |
Effects of metoclopramide and bethanechol on delayed gastric emptying present in gastroesophageal reflux patients.
Topics: Bethanechol; Bethanechol Compounds; Gastric Emptying; Gastroesophageal Reflux; Humans; Metoclopramid | 1983 |
Bethanechol chloride oral solutions: stability and use in infants.
Topics: Bethanechol; Drug Stability; Gastric Acid; Gastroesophageal Reflux; Humans; Infant; Muscarinic Agoni | 1997 |
Bethanechol versus antiacids in the treatment of gastroesophageal reflux.
Topics: Aluminum Hydroxide; Antacids; Bethanechol; Bethanechol Compounds; Child, Preschool; Clinical Trials | 1985 |
14 other studies available for bethanechol and Gastroesophageal Reflux
| Article | Year |
|---|---|
Gastro-oesophageal reflux in children.
Topics: Age Factors; Bethanechol; Bethanechol Compounds; Child; Child, Preschool; Gastroesophageal Reflux; H | 1982 |
[Gastroesophageal reflux disease and reflux esophagitis. Therapeutic modifiability by bethanechol chloride].
Topics: Adult; Aged; Bethanechol; Bethanechol Compounds; Esophagitis, Peptic; Female; Gastroesophageal Reflu | 1982 |
Bethanechol and gastroesophageal reflux in asthma.
Topics: Asthma; Bethanechol; Bethanechol Compounds; Gastroesophageal Reflux; Humans | 1984 |
Galactorrhea caused by esophagitis.
Topics: Adult; Anti-Ulcer Agents; Bethanechol; Esophagitis; Famotidine; Female; Galactorrhea; Gastroesophage | 1995 |
Altered esophageal pain threshold in irritable bowel syndrome.
Topics: Adult; Aged; Analysis of Variance; Bethanechol; Bethanechol Compounds; Colonic Diseases, Functional; | 1993 |
Proximal pH-metry for diagnosis of upper airway complications of gastroesophageal reflux.
Topics: Airway Obstruction; Antiemetics; Bethanechol; Child, Preschool; Choanal Atresia; Cimetidine; Endosco | 1995 |
Prokinetics in the treatment of gastro-oesophageal reflux disease. International symposium. Paris, France, 5 September 1996.
Topics: Barrett Esophagus; Bethanechol; Cisapride; Gastric Emptying; Gastroesophageal Reflux; Gastrointestin | 1998 |
[Effect of bethanecol and prostaglandin E2 on gastroesophageal reflux and esophageal emptying, in patients with reflux esophagitis proposed for surgical therapy].
Topics: Bethanechol; Bethanechol Compounds; Dinoprostone; Esophagitis, Peptic; Esophagus; Female; Gastric Em | 1985 |
Apnea and bradycardia in a preterm neonate.
Topics: Antacids; Apnea; Bethanechol; Bethanechol Compounds; Bradycardia; Gastroesophageal Reflux; Humans; H | 1985 |
Effect of bethanechol and metoclopramide on upper gastrointestinal motility in the kitten.
Topics: Animals; Bethanechol; Bethanechol Compounds; Cats; Esophagogastric Junction; Esophagus; Gastric Empt | 1986 |
Early effects of bethanechol on the esophageal motor function of infants with gastroesophageal reflux.
Topics: Bethanechol; Bethanechol Compounds; Esophagus; Gastroesophageal Reflux; Humans; Infant; Manometry; P | 1986 |
A critical review of current medical therapy for gastroesophageal reflux disease.
Topics: Alginates; Antacids; Barrett Esophagus; Bethanechol; Bethanechol Compounds; Cimetidine; Gastroesopha | 1986 |
Bethanechol increases the diagnostic yield in patients with esophageal chest pain.
Topics: Adult; Aged; Bethanechol; Bethanechol Compounds; Esophageal Diseases; Esophagus; Female; Gastroesoph | 1986 |
Acute dystonic reaction to bethanechol--a direct acetylcholine receptor agonist.
Topics: Acute Disease; Bethanechol; Bethanechol Compounds; Dystonia; Gastroesophageal Reflux; Humans; Infant | 1986 |