bethanechol has been researched along with Colonic Neoplasms in 3 studies
Bethanechol: A slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, HEART RATE changes, and BRONCHIAL SPASM.
bethanechol : The carbamic acid ester of 2-methylcholine. A slowly hydrolysed muscarinic agonist with no nicotinic effects, it is used as its chloride salt to increase smooth muscle tone, as in the gastrointestinal tract following abdominal surgery, treatment of gastro-oesophageal reflux disease, and as an alternative to catheterisation in the treatment of non-obstructive urinary retention.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Circular colonic smooth muscle strips from patients with ulcerative colitis, acute diverticular disease, or adenocarcinoma were stretched to the optimal length and stimulated with electrical field stimulation (EFS), bethanechol, or increased concentrations of extracellular K+." | 3.68 | Defect in colonic smooth muscle contraction in patients with ulcerative colitis. ( Hyman, PE; Snape, WJ; Williams, R, 1991) |
| "Bethanechol treatment increased the thickness of normal colonic mucosa and the expression of selected matrix metalloproteinase (Mmp) genes, including Mmp7, Mmp10 and Mmp13." | 1.39 | Cholinergic muscarinic receptor activation augments murine intestinal epithelial cell proliferation and tumorigenesis. ( Drachenberg, C; Heath, J; Peng, Z; Raufman, JP; Xie, G, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peng, Z | 1 |
| Heath, J | 1 |
| Drachenberg, C | 1 |
| Raufman, JP | 1 |
| Xie, G | 1 |
| Davies, AN | 1 |
| Vriens, J | 1 |
| Snape, WJ | 1 |
| Williams, R | 1 |
| Hyman, PE | 1 |
3 other studies available for bethanechol and Colonic Neoplasms
| Article | Year |
|---|---|
Cholinergic muscarinic receptor activation augments murine intestinal epithelial cell proliferation and tumorigenesis.
Topics: Adenocarcinoma; Animals; Azoxymethane; Bethanechol; Cell Proliferation; Cell Transformation, Neoplas | 2013 |
Oral transmucosal fentanyl citrate and xerostomia.
Topics: Administration, Buccal; Analgesics, Opioid; Back Pain; Bethanechol; Colonic Neoplasms; Drug Combinat | 2005 |
Defect in colonic smooth muscle contraction in patients with ulcerative colitis.
Topics: Adenocarcinoma; Adult; Bethanechol; Bethanechol Compounds; Colitis, Ulcerative; Colon; Colonic Neopl | 1991 |