Page last updated: 2024-10-23

bethanechol and Colitis

bethanechol has been researched along with Colitis in 5 studies

Bethanechol: A slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, HEART RATE changes, and BRONCHIAL SPASM.
bethanechol : The carbamic acid ester of 2-methylcholine. A slowly hydrolysed muscarinic agonist with no nicotinic effects, it is used as its chloride salt to increase smooth muscle tone, as in the gastrointestinal tract following abdominal surgery, treatment of gastro-oesophageal reflux disease, and as an alternative to catheterisation in the treatment of non-obstructive urinary retention.

Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Research Excerpts

ExcerptRelevanceReference
"Colitis was induced by 4% DSS water, given orally."1.35Loss of Ca-mediated ion transport during colitis correlates with reduced ion transport responses to a Ca-activated K channel opener. ( Hirota, CL; McKay, DM, 2009)
"Colitis was induced in the distal colon by rectal infusion of formaldehyde solution, followed by an intravenous bolus of soluble immune complexes."1.27Effect of acute experimental colitis on rabbit colonic smooth muscle. ( Cohen, JD; Kao, HW; Lechago, J; Snape, WJ; Tan, ST, 1986)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nomura, R1
Yanagihara, M1
Sato, H1
Matsumoto, K1
Tashima, K1
Horie, S1
Chen, S1
Fujino, H1
Ueno, K1
Murayama, T1
Hirota, CL2
McKay, DM2
Lomax, AE1
O'Hara, JR1
Hyland, NP1
Mawe, GM1
Sharkey, KA1
Cohen, JD1
Kao, HW1
Tan, ST1
Lechago, J1
Snape, WJ1

Other Studies

5 other studies available for bethanechol and Colitis

ArticleYear
Bee venom phospholipase A2-induced phasic contractions in mouse rectum: independent roles of eicosanoid and gap junction proteins and their loss in experimental colitis.
    European journal of pharmacology, 2013, Oct-15, Volume: 718, Issue:1-3

    Topics: Animals; Bee Venoms; Bethanechol; Carbenoxolone; Colitis; Connexin 43; Dextran Sulfate; Eicosanoids;

2013
Loss of Ca-mediated ion transport during colitis correlates with reduced ion transport responses to a Ca-activated K channel opener.
    British journal of pharmacology, 2009, Volume: 156, Issue:7

    Topics: Animals; Bethanechol; Biological Transport, Active; Calcium; Chlorides; Colitis; Colon; Dextran Sulf

2009
Persistent alterations to enteric neural signaling in the guinea pig colon following the resolution of colitis.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 292, Issue:2

    Topics: Action Potentials; Animals; Bethanechol; Body Weight; Cell Count; Colforsin; Colitis; Colon; Enteric

2007
M3 muscarinic receptor-deficient mice retain bethanechol-mediated intestinal ion transport and are more sensitive to colitis.
    Canadian journal of physiology and pharmacology, 2006, Volume: 84, Issue:11

    Topics: Animals; Bethanechol; Cholinergic Fibers; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; I

2006
Effect of acute experimental colitis on rabbit colonic smooth muscle.
    The American journal of physiology, 1986, Volume: 251, Issue:4 Pt 1

    Topics: Action Potentials; Animals; Bethanechol; Bethanechol Compounds; Colitis; Colon; Electric Conductivit

1986