bethanechol has been researched along with Colitis Gravis in 3 studies
Bethanechol: A slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, HEART RATE changes, and BRONCHIAL SPASM.
bethanechol : The carbamic acid ester of 2-methylcholine. A slowly hydrolysed muscarinic agonist with no nicotinic effects, it is used as its chloride salt to increase smooth muscle tone, as in the gastrointestinal tract following abdominal surgery, treatment of gastro-oesophageal reflux disease, and as an alternative to catheterisation in the treatment of non-obstructive urinary retention.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Circular colonic smooth muscle strips from patients with ulcerative colitis, acute diverticular disease, or adenocarcinoma were stretched to the optimal length and stimulated with electrical field stimulation (EFS), bethanechol, or increased concentrations of extracellular K+." | 3.68 | Defect in colonic smooth muscle contraction in patients with ulcerative colitis. ( Hyman, PE; Snape, WJ; Williams, R, 1991) |
| " The decrease in muscle contraction was observed with bethanechol stimulation or electrical field stimulation." | 3.67 | Role of inflammatory mediators in colonic smooth muscle function in ulcerative colitis. ( Kao, HW; Snape, WJ, 1988) |
| "Nicotine has been shown to reduce both tone and muscular activity in the human colon by releasing nitric oxide (NO) from nerves." | 1.35 | Nicotine-induced neurogenic relaxation in the mouse colon: changes with dextran sodium sulfate-induced colitis. ( Fujino, H; Hamada, Y; Horie, S; Murakami, I; Murayama, T; Yamane, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Murakami, I | 1 |
| Hamada, Y | 1 |
| Yamane, S | 1 |
| Fujino, H | 1 |
| Horie, S | 1 |
| Murayama, T | 1 |
| Snape, WJ | 2 |
| Williams, R | 1 |
| Hyman, PE | 1 |
| Kao, HW | 1 |
3 other studies available for bethanechol and Colitis Gravis
| Article | Year |
|---|---|
Nicotine-induced neurogenic relaxation in the mouse colon: changes with dextran sodium sulfate-induced colitis.
Topics: Animals; Atropine; Bethanechol; Colitis, Ulcerative; Colon; Colon, Descending; Colon, Transverse; De | 2009 |
Defect in colonic smooth muscle contraction in patients with ulcerative colitis.
Topics: Adenocarcinoma; Adult; Bethanechol; Bethanechol Compounds; Colitis, Ulcerative; Colon; Colonic Neopl | 1991 |
Role of inflammatory mediators in colonic smooth muscle function in ulcerative colitis.
Topics: Animals; Bethanechol; Bethanechol Compounds; Colitis, Ulcerative; Colon; Electric Stimulation; Gastr | 1988 |