bethanechol has been researched along with Cardiac Toxicity in 1 studies
Bethanechol: A slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, HEART RATE changes, and BRONCHIAL SPASM.
bethanechol : The carbamic acid ester of 2-methylcholine. A slowly hydrolysed muscarinic agonist with no nicotinic effects, it is used as its chloride salt to increase smooth muscle tone, as in the gastrointestinal tract following abdominal surgery, treatment of gastro-oesophageal reflux disease, and as an alternative to catheterisation in the treatment of non-obstructive urinary retention.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cardiotoxicity is a seriously debilitating complication of trastuzumab (TRZ) therapy in patients with cancer as a consequence of overexpression of the human epidermal growth factor receptor 2." | 1.91 | Acetylcholine receptor agonists effectively attenuated multiple program cell death pathways and improved left ventricular function in trastuzumab-induced cardiotoxicity in rats. ( Arinno, A; Arunsak, B; Chattipakorn, N; Chattipakorn, SC; Chunchai, T; Kerdphoo, S; Khuanjing, T; Maneechote, C; Ongnok, B; Prathumsap, N, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Prathumsap, N | 1 |
| Ongnok, B | 1 |
| Khuanjing, T | 1 |
| Arinno, A | 1 |
| Maneechote, C | 1 |
| Chunchai, T | 1 |
| Arunsak, B | 1 |
| Kerdphoo, S | 1 |
| Chattipakorn, SC | 1 |
| Chattipakorn, N | 1 |
1 other study available for bethanechol and Cardiac Toxicity
| Article | Year |
|---|---|
Acetylcholine receptor agonists effectively attenuated multiple program cell death pathways and improved left ventricular function in trastuzumab-induced cardiotoxicity in rats.
Topics: Adult; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bethanechol; Cardiotoxicity; Cell Death; He | 2023 |