bethanechol has been researched along with Cancer of Head in 8 studies
Bethanechol: A slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, HEART RATE changes, and BRONCHIAL SPASM.
bethanechol : The carbamic acid ester of 2-methylcholine. A slowly hydrolysed muscarinic agonist with no nicotinic effects, it is used as its chloride salt to increase smooth muscle tone, as in the gastrointestinal tract following abdominal surgery, treatment of gastro-oesophageal reflux disease, and as an alternative to catheterisation in the treatment of non-obstructive urinary retention.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study suggests that bethanechol chloride therapy may be effective in patients with xerostomia and hyposalivation." | 9.41 | Efficacy of bethanechol chloride in the treatment of radiation-induced xerostomia in patients with head and neck cancer: A systematic review and meta-analysis. ( Abreu Alves, F; Azeredo Alves Antunes, L; Baena Elchin, C; da Graça Pinto, H; Moral Nakamura, D; Pena Coto, N; Thomazotti Berard, L, 2023) |
| "The aim of this study was to determine the impact of bethanechol administration concomitant to radiotherapy (RT) on oral mucositis, candidiasis and taste loss." | 9.14 | A randomized phase III prospective trial of bethanechol to prevent mucositis, candidiasis, and taste loss in patients with head and neck cancer undergoing radiotherapy: a secondary analysis. ( Carvalho, AL; Chen, H; Freire, AR; Jham, BC, 2009) |
| "The effects of bethanechol in the treatment of dry mouth were assessed in patients with xerostomia after radiation therapy to the head and neck." | 9.07 | A clinical trial of bethanechol in patients with xerostomia after radiation therapy. A pilot study. ( Burchell, JL; Emerton, S; Epstein, JB; Le, ND; Silverman, S, 1994) |
| "The present study suggests that bethanechol chloride therapy may be effective in patients with xerostomia and hyposalivation." | 5.41 | Efficacy of bethanechol chloride in the treatment of radiation-induced xerostomia in patients with head and neck cancer: A systematic review and meta-analysis. ( Abreu Alves, F; Azeredo Alves Antunes, L; Baena Elchin, C; da Graça Pinto, H; Moral Nakamura, D; Pena Coto, N; Thomazotti Berard, L, 2023) |
| "The aim of this study was to determine the impact of bethanechol administration concomitant to radiotherapy (RT) on oral mucositis, candidiasis and taste loss." | 5.14 | A randomized phase III prospective trial of bethanechol to prevent mucositis, candidiasis, and taste loss in patients with head and neck cancer undergoing radiotherapy: a secondary analysis. ( Carvalho, AL; Chen, H; Freire, AR; Jham, BC, 2009) |
| "The aim of this study was to verify whether the use of bethanechol during radiotherapy (RT) for head and neck cancer (HNC) prevents radiation-induced xerostomia and salivary flow reduction." | 5.12 | A randomized phase III prospective trial of bethanechol to prevent radiotherapy-induced salivary gland damage in patients with head and neck cancer. ( Aboud, CG; Carvalho, AL; Coelho, Mde M; Freire, AR; Jham, BC; Teixeira, IV, 2007) |
| "The effects of bethanechol in the treatment of dry mouth were assessed in patients with xerostomia after radiation therapy to the head and neck." | 5.07 | A clinical trial of bethanechol in patients with xerostomia after radiation therapy. A pilot study. ( Burchell, JL; Emerton, S; Epstein, JB; Le, ND; Silverman, S, 1994) |
| "Some studies have shown evidence that the prophylactic use of bethanechol chloride (BC) may be useful in preventing the incidence and/or severity of xerostomia (XT)." | 3.85 | Influence of bethanechol on salivary parameters in irradiated patients. ( Abreu-Alves, F; Campos, L; Cotomacio, C; Crosato, EM; Jaguar, G; Simões, A, 2017) |
| "Bethanechol was effective in decreasing the salivary gland damage." | 2.80 | Double blind randomized prospective trial of bethanechol in the prevention of radiation-induced salivary gland dysfunction in head and neck cancer patients. ( Alves, FA; Boccaletti, KW; Carvalho, AL; Jaguar, GC; Kowalski, LP; Lima, EN; Pellizzon, AC, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dhaliwal, JS | 1 |
| Talip, T | 1 |
| Rajam, DT | 1 |
| Dhaliwal, SKS | 1 |
| Murang, ZR | 1 |
| Ming, LC | 1 |
| Venkatasalu, MR | 1 |
| Moral Nakamura, D | 1 |
| da Graça Pinto, H | 1 |
| Baena Elchin, C | 1 |
| Thomazotti Berard, L | 1 |
| Abreu Alves, F | 1 |
| Azeredo Alves Antunes, L | 1 |
| Pena Coto, N | 1 |
| Jaguar, GC | 1 |
| Lima, EN | 1 |
| Kowalski, LP | 1 |
| Pellizzon, AC | 1 |
| Carvalho, AL | 3 |
| Boccaletti, KW | 1 |
| Alves, FA | 1 |
| Cotomacio, C | 1 |
| Campos, L | 1 |
| Simões, A | 1 |
| Jaguar, G | 1 |
| Crosato, EM | 1 |
| Abreu-Alves, F | 1 |
| Jham, BC | 2 |
| Chen, H | 1 |
| Freire, AR | 2 |
| Gorsky, M | 1 |
| Epstein, JB | 2 |
| Parry, J | 1 |
| Epstein, MS | 1 |
| Le, ND | 2 |
| Silverman, S | 2 |
| Teixeira, IV | 1 |
| Aboud, CG | 1 |
| Coelho, Mde M | 1 |
| Burchell, JL | 1 |
| Emerton, S | 1 |
2 reviews available for bethanechol and Cancer of Head
| Article | Year |
|---|---|
A systematic review of interventional studies on oral care of palliative patients.
Topics: Benzydamine; Bethanechol; Head and Neck Neoplasms; Humans; Ketamine; Morphine Derivatives; Mouthwash | 2022 |
Efficacy of bethanechol chloride in the treatment of radiation-induced xerostomia in patients with head and neck cancer: A systematic review and meta-analysis.
Topics: Bethanechol; Head and Neck Neoplasms; Humans; Radiation Injuries; Salivary Glands; Sexually Transmit | 2023 |
5 trials available for bethanechol and Cancer of Head
| Article | Year |
|---|---|
Double blind randomized prospective trial of bethanechol in the prevention of radiation-induced salivary gland dysfunction in head and neck cancer patients.
Topics: Adult; Aged; Bethanechol; Dose-Response Relationship, Radiation; Double-Blind Method; Female; Head a | 2015 |
A randomized phase III prospective trial of bethanechol to prevent mucositis, candidiasis, and taste loss in patients with head and neck cancer undergoing radiotherapy: a secondary analysis.
Topics: Adult; Aged; Ageusia; Bethanechol; Candidiasis, Oral; Cranial Irradiation; Female; Head and Neck Neo | 2009 |
The efficacy of pilocarpine and bethanechol upon saliva production in cancer patients with hyposalivation following radiation therapy.
Topics: Adult; Aged; Aged, 80 and over; Attitude to Health; Bethanechol; Cross-Over Studies; Female; Head an | 2004 |
A randomized phase III prospective trial of bethanechol to prevent radiotherapy-induced salivary gland damage in patients with head and neck cancer.
Topics: Adult; Aged; Bethanechol; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Stagi | 2007 |
A clinical trial of bethanechol in patients with xerostomia after radiation therapy. A pilot study.
Topics: Bethanechol; Bethanechol Compounds; Carcinoma, Squamous Cell; Cranial Irradiation; Female; Head and | 1994 |
1 other study available for bethanechol and Cancer of Head
| Article | Year |
|---|---|
Influence of bethanechol on salivary parameters in irradiated patients.
Topics: Adolescent; Adult; Aged; Bethanechol; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Ra | 2017 |