Page last updated: 2024-10-23

bethanechol and Brain Diseases

bethanechol has been researched along with Brain Diseases in 2 studies

Bethanechol: A slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, HEART RATE changes, and BRONCHIAL SPASM.
bethanechol : The carbamic acid ester of 2-methylcholine. A slowly hydrolysed muscarinic agonist with no nicotinic effects, it is used as its chloride salt to increase smooth muscle tone, as in the gastrointestinal tract following abdominal surgery, treatment of gastro-oesophageal reflux disease, and as an alternative to catheterisation in the treatment of non-obstructive urinary retention.

Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.

Research Excerpts

ExcerptRelevanceReference
"Microinjections of the cholinergic agonists, carbachol and bethanechol, either into the amygdala or into the dorsal hippocampus produced sustained limbic seizures and brain damage in rats."3.66Cholinomimetics produce seizures and brain damage in rats. ( Czuczwar, SJ; Kleinrok, Z; Turski, L; Turski, WA, 1983)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nakai, K1
Kasamatsu, T1
Turski, WA1
Czuczwar, SJ1
Kleinrok, Z1
Turski, L1

Other Studies

2 other studies available for bethanechol and Brain Diseases

ArticleYear
Accelerated regeneration of central catecholamine fibers in cat occipital cortex: effects of substance P.
    Brain research, 1984, Dec-10, Volume: 323, Issue:2

    Topics: Animals; Bethanechol; Bethanechol Compounds; Brain Diseases; Cats; Histocytochemistry; Hydroxydopami

1984
Cholinomimetics produce seizures and brain damage in rats.
    Experientia, 1983, Dec-15, Volume: 39, Issue:12

    Topics: Amygdala; Animals; Bethanechol; Bethanechol Compounds; Brain; Brain Diseases; Carbachol; Hippocampus

1983