bethanechol has been researched along with Bladder Neck Obstruction in 23 studies
Bethanechol: A slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, HEART RATE changes, and BRONCHIAL SPASM.
bethanechol : The carbamic acid ester of 2-methylcholine. A slowly hydrolysed muscarinic agonist with no nicotinic effects, it is used as its chloride salt to increase smooth muscle tone, as in the gastrointestinal tract following abdominal surgery, treatment of gastro-oesophageal reflux disease, and as an alternative to catheterisation in the treatment of non-obstructive urinary retention.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bladder outlet obstruction secondary to benign prostatic hyperplasia induces numerous changes in bladder morphology, physiology, and pharmacology." | 2.38 | Effect of bladder outlet obstruction on the morphology, physiology, and pharmacology of the bladder. ( Kato, K; Levin, RM; Longhurst, PA; Monson, FC; Wein, AJ, 1990) |
| "We used a model of bladder outlet obstruction in male guinea pigs as a way to produce detrusor overactivity." | 1.42 | Conscious voiding during bladder obstruction in guinea pigs correlates with contractile activity of isolated bladders. ( Brookes, S; Costa, M; Gibbins, I; Keightley, L; Nicholas, S; Zagorodnyuk, V, 2015) |
| "Partial bladder outlet obstruction was surgically induced in twenty New Zealand White rabbits." | 1.30 | Metabolic basis for contractile dysfunction following chronic partial bladder outlet obstruction in rabbits. ( Haugaard, N; Levin, RM; Nigro, DA; Wein, AJ, 1999) |
| "Thapsigargin has been shown to selectively block the sarcoplasmic Ca-ATPase, thereby preventing the reuptake of calcium into intracellular stores and the participation of these calcium storage sites in the contractile response to stimulation." | 1.29 | Effect of thapsigargin on the contractile response of the normal and obstructed rabbit urinary bladder. ( Levin, RM; Rohrmann, D; Wein, AJ; Zderic, SA, 1996) |
| "Experimental bladder outlet obstruction in cats was produced by surgical placement of a silastic cuff around the urethra." | 1.28 | Short term functional effects of bladder outlet obstruction in the cat. ( Elbadawi, A; Kato, K; Levin, RM; Longhurst, PA; McGuire, EJ; Miller, LF; Radzinski, C; Wein, AJ, 1990) |
| "Studies on the effect of partial bladder outlet obstruction demonstrate that significant alterations in urinary bladder structure and function occur within 24 hours of the creation of the obstruction." | 1.28 | Effect of acute complete obstruction on the rabbit urinary bladder. ( Kato, K; Kitada, S; Levin, RM; Wein, AJ, 1989) |
| "Partial bladder outlet obstruction is a commonly encountered pathophysiologic state." | 1.27 | Recovery from short-term obstruction of the rabbit urinary bladder. ( Atta, MA; Elbadawi, A; Levin, RM; Malkowicz, SB; Wein, AJ, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (21.74) | 18.7374 |
| 1990's | 15 (65.22) | 18.2507 |
| 2000's | 2 (8.70) | 29.6817 |
| 2010's | 1 (4.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nicholas, S | 1 |
| Keightley, L | 1 |
| Brookes, S | 1 |
| Costa, M | 1 |
| Gibbins, I | 1 |
| Zagorodnyuk, V | 1 |
| Hashimoto, T | 1 |
| Nagabukuro, H | 1 |
| Doi, T | 1 |
| Levin, RM | 18 |
| High, J | 1 |
| Wein, AJ | 17 |
| Saito, M | 5 |
| Roelofs, M | 1 |
| Monson, FC | 3 |
| Passerini-Glazel, G | 1 |
| Koteliansky, VE | 1 |
| Sartore, S | 1 |
| Packard, D | 1 |
| Cohen, A | 1 |
| Haugaard, N | 5 |
| Longhurst, PA | 6 |
| Tammela, TL | 1 |
| Riffaud, JP | 2 |
| Bellamy, F | 2 |
| Rohrmann, D | 3 |
| Habib, M | 1 |
| Krasnopolsky, L | 2 |
| Zhao, Y | 2 |
| Kwon, HY | 1 |
| Parsons, K | 1 |
| Zderic, SA | 1 |
| Ohmura, M | 2 |
| Kondo, A | 2 |
| Yokoi, K | 1 |
| Yu, HJ | 1 |
| Damaser, MS | 1 |
| Nigro, DA | 1 |
| O'Connor, L | 1 |
| Buttyan, R | 1 |
| Das, A | 1 |
| Dixon, JS | 1 |
| Gosling, JA | 1 |
| Kato, K | 4 |
| Radzinski, C | 1 |
| McGuire, EJ | 1 |
| Miller, LF | 1 |
| Elbadawi, A | 3 |
| Kitada, S | 1 |
| Malkowicz, SB | 2 |
| Atta, MA | 1 |
| Van Arsdalen, K | 1 |
| Ruggieri, MR | 1 |
2 reviews available for bethanechol and Bladder Neck Obstruction
| Article | Year |
|---|---|
Effect of bladder outlet obstruction on the morphology, physiology, and pharmacology of the bladder.
Topics: Animals; Bethanechol; Bethanechol Compounds; Male; Models, Biological; Muscle Contraction; Pressure; | 1990 |
Pharmacologic treatment of lower urinary tract dysfunction in the female patient.
Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Bethanechol; Bethanechol Co | 1985 |
21 other studies available for bethanechol and Bladder Neck Obstruction
| Article | Year |
|---|---|
Conscious voiding during bladder obstruction in guinea pigs correlates with contractile activity of isolated bladders.
Topics: Animals; Bethanechol; Cholinesterase Inhibitors; Consciousness; Disease Models, Animal; Dose-Respons | 2015 |
Effects of the selective acetylcholinesterase inhibitor TAK-802 on the voiding behavior and bladder mass increase in rats with partial bladder outlet obstruction.
Topics: Administration, Oral; Animals; Bethanechol; Cholinesterase Inhibitors; Dose-Response Relationship, D | 2005 |
The effect of short-term obstruction on urinary bladder function in the rabbit.
Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Electric Stimulation; Epinephri | 1984 |
Effect of partial outlet obstruction on contractility: comparison between severe and mild obstruction.
Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Disease Models, Animal; Electri | 1993 |
Contractility and phenotype transitions in serosal thickening of obstructed rabbit bladder.
Topics: Animals; Bethanechol; Cytoskeletal Proteins; Cytoskeleton; Fluorescent Antibody Technique; Immunohis | 1995 |
Effect of partial outlet obstruction on choline acetyltransferase activity in the rat and rabbit.
Topics: Animals; Bethanechol; Bethanechol Compounds; Choline O-Acetyltransferase; Electric Stimulation; In V | 1993 |
Effects of partial outlet obstruction of the rat urinary bladder on micturition characteristics, DNA synthesis and the contractile response to field stimulation and pharmacological agents.
Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Circadian Rhythm; DNA; Electric | 1993 |
Protective effect of Tadenan on bladder function secondary to partial outlet obstruction.
Topics: Adenosine Triphosphate; Animals; Bethanechol; DNA; Fatty Alcohols; Male; Plant Extracts; Potassium C | 1996 |
Effects of partial outlet obstruction on bladder-strip sensitivity to glucose deprivation: an in vitro study in the rat.
Topics: Analysis of Variance; Animals; Bethanechol; Electric Stimulation; Glucose; In Vitro Techniques; Male | 1996 |
Effect of thapsigargin on the contractile response of the normal and obstructed rabbit urinary bladder.
Topics: Animals; Bethanechol; Calcium-Transporting ATPases; Electric Stimulation; Enzyme Inhibitors; In Vitr | 1996 |
Effects of tadenan pretreatment on bladder physiology and biochemistry following partial outlet obstruction.
Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bethanechol; Electric Stim | 1996 |
Restoration of rat bladder function following release of short- and long-term partial outflow obstruction.
Topics: Adenosine Triphosphate; Animals; Bethanechol; Cystostomy; Electric Stimulation; In Vitro Techniques; | 1997 |
Effect of ischemia and partial outflow obstruction on rat bladder function.
Topics: Animals; Bethanechol; Ischemia; Male; Muscle Contraction; Organ Size; Parasympathomimetics; Rats; Ra | 1997 |
Ability of obstructed bladders to empty is dependent on method of stimulation.
Topics: Animals; Bethanechol; Electric Stimulation; Male; Parasympathomimetics; Potassium Chloride; Rabbits; | 1997 |
Metabolic basis for contractile dysfunction following chronic partial bladder outlet obstruction in rabbits.
Topics: Animals; Bethanechol; Citrate (si)-Synthase; Electric Stimulation; In Vitro Techniques; Muscle Contr | 1999 |
Obstructive response of human bladder to BPH vs. rabbit bladder response to partial outlet obstruction: a direct comparison.
Topics: Adaptation, Physiological; Animals; Bethanechol; Calcium Signaling; Calcium-Transporting ATPases; Ca | 2000 |
The functional effects of long-term outlet obstruction on the rabbit urinary bladder.
Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Chronic Disease; In Vitro Techn | 1990 |
Short term functional effects of bladder outlet obstruction in the cat.
Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Cats; Disease Models, Animal; F | 1990 |
Effect of acute complete obstruction on the rabbit urinary bladder.
Topics: Animals; Bethanechol; Bethanechol Compounds; Electric Stimulation; Hexamethonium; Hexamethonium Comp | 1989 |
Recovery from short-term obstruction of the rabbit urinary bladder.
Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Isoproterenol; Male; Methoxamin | 1985 |
Acute biochemical and functional alterations in the partially obstructed rabbit urinary bladder.
Topics: Animals; Bethanechol; Bethanechol Compounds; Egtazic Acid; Electric Stimulation; Hydroxyproline; In | 1986 |