Page last updated: 2024-10-23

bethanechol and Asialia

bethanechol has been researched along with Asialia in 12 studies

Bethanechol: A slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, HEART RATE changes, and BRONCHIAL SPASM.
bethanechol : The carbamic acid ester of 2-methylcholine. A slowly hydrolysed muscarinic agonist with no nicotinic effects, it is used as its chloride salt to increase smooth muscle tone, as in the gastrointestinal tract following abdominal surgery, treatment of gastro-oesophageal reflux disease, and as an alternative to catheterisation in the treatment of non-obstructive urinary retention.

Research Excerpts

ExcerptRelevanceReference
"The present study suggests that bethanechol chloride therapy may be effective in patients with xerostomia and hyposalivation."9.41Efficacy of bethanechol chloride in the treatment of radiation-induced xerostomia in patients with head and neck cancer: A systematic review and meta-analysis. ( Abreu Alves, F; Azeredo Alves Antunes, L; Baena Elchin, C; da Graça Pinto, H; Moral Nakamura, D; Pena Coto, N; Thomazotti Berard, L, 2023)
"The effects of bethanechol in the treatment of dry mouth were assessed in patients with xerostomia after radiation therapy to the head and neck."9.07A clinical trial of bethanechol in patients with xerostomia after radiation therapy. A pilot study. ( Burchell, JL; Emerton, S; Epstein, JB; Le, ND; Silverman, S, 1994)
"The present study suggests that bethanechol chloride therapy may be effective in patients with xerostomia and hyposalivation."5.41Efficacy of bethanechol chloride in the treatment of radiation-induced xerostomia in patients with head and neck cancer: A systematic review and meta-analysis. ( Abreu Alves, F; Azeredo Alves Antunes, L; Baena Elchin, C; da Graça Pinto, H; Moral Nakamura, D; Pena Coto, N; Thomazotti Berard, L, 2023)
"The aim of this study was to verify whether the use of bethanechol during radiotherapy (RT) for head and neck cancer (HNC) prevents radiation-induced xerostomia and salivary flow reduction."5.12A randomized phase III prospective trial of bethanechol to prevent radiotherapy-induced salivary gland damage in patients with head and neck cancer. ( Aboud, CG; Carvalho, AL; Coelho, Mde M; Freire, AR; Jham, BC; Teixeira, IV, 2007)
"The effects of bethanechol in the treatment of dry mouth were assessed in patients with xerostomia after radiation therapy to the head and neck."5.07A clinical trial of bethanechol in patients with xerostomia after radiation therapy. A pilot study. ( Burchell, JL; Emerton, S; Epstein, JB; Le, ND; Silverman, S, 1994)
"A MEDLINE/PubMed search was conducted using the terms "Xerostomia" AND, "Saliva Artificial" OR, "Citric Acid," "Malic Acid," "Chewing Gum," "Acupuncture" OR, "Pilocarpine" OR, "Bethanechol" OR, "Cevimeline" OR, "Hyperbaric Oxygen Therapy" OR, "Stem Cell Therapy" OR "Genetic Therapy" and their Mesh Terms."4.98Salivary hypofunction: An update on therapeutic strategies. ( Cherubini, K; Figueiredo, MAZ; Medella-Junior, FAC; Salum, FG, 2018)
"Some studies have shown evidence that the prophylactic use of bethanechol chloride (BC) may be useful in preventing the incidence and/or severity of xerostomia (XT)."3.85Influence of bethanechol on salivary parameters in irradiated patients. ( Abreu-Alves, F; Campos, L; Cotomacio, C; Crosato, EM; Jaguar, G; Simões, A, 2017)
"Bethanechol was effective in decreasing the salivary gland damage."2.80Double blind randomized prospective trial of bethanechol in the prevention of radiation-induced salivary gland dysfunction in head and neck cancer patients. ( Alves, FA; Boccaletti, KW; Carvalho, AL; Jaguar, GC; Kowalski, LP; Lima, EN; Pellizzon, AC, 2015)
"Pirenzepine is an antisecretory anticholinergic type drug that has recently been shown to be relatively free of usual anticholinergic side effects on esophageal smooth muscle."1.27Pirenzepine and propantheline effects on esophageal pressure responses to bethanechol. ( Castell, DO; Castell, JA; Dalton, CB; Hassan, M, 1986)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's2 (16.67)18.2507
2000's3 (25.00)29.6817
2010's3 (25.00)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Campanhã, D1
PereiraLIMA, EN1
Alves, FA2
Jaguar, GC2
Moral Nakamura, D1
da Graça Pinto, H1
Baena Elchin, C1
Thomazotti Berard, L1
Abreu Alves, F1
Azeredo Alves Antunes, L1
Pena Coto, N1
Salum, FG1
Medella-Junior, FAC1
Figueiredo, MAZ1
Cherubini, K1
Lima, EN1
Kowalski, LP1
Pellizzon, AC1
Carvalho, AL2
Boccaletti, KW1
Cotomacio, C1
Campos, L1
Simões, A1
Jaguar, G1
Crosato, EM1
Abreu-Alves, F1
Gorsky, M1
Epstein, JB2
Parry, J1
Epstein, MS1
Le, ND2
Silverman, S2
Davies, AN1
Vriens, J1
Jham, BC1
Teixeira, IV1
Aboud, CG1
Coelho, Mde M1
Freire, AR1
Yoder, V1
Burchell, JL1
Emerton, S1
Ferguson, MM1
Hassan, M1
Dalton, CB1
Castell, JA1
Castell, DO1

Reviews

3 reviews available for bethanechol and Asialia

ArticleYear
Efficacy of bethanechol chloride in the treatment of radiation-induced xerostomia in patients with head and neck cancer: A systematic review and meta-analysis.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2023, Volume: 186

    Topics: Bethanechol; Head and Neck Neoplasms; Humans; Radiation Injuries; Salivary Glands; Sexually Transmit

2023
Salivary hypofunction: An update on therapeutic strategies.
    Gerodontology, 2018, Volume: 35, Issue:4

    Topics: Acupuncture Therapy; Bethanechol; Chewing Gum; Humans; Hyperbaric Oxygenation; Muscarinic Agonists;

2018
Pilocarpine and other cholinergic drugs in the management of salivary gland dysfunction.
    Oral surgery, oral medicine, and oral pathology, 1993, Volume: 75, Issue:2

    Topics: Anethole Trithione; Bethanechol; Bethanechol Compounds; Humans; Parasympathomimetics; Pilocarpine; P

1993

Trials

5 trials available for bethanechol and Asialia

ArticleYear
Bethanechol used to prevent salivary gland dysfunction in patients submitted to radioactive iodine therapy: A double blind, placebo-controlled, randomized study.
    Journal of stomatology, oral and maxillofacial surgery, 2022, Volume: 123, Issue:5

    Topics: Bethanechol; Humans; Iodine Radioisotopes; Quality of Life; Salivary Glands; Thyroid Neoplasms; Xero

2022
Double blind randomized prospective trial of bethanechol in the prevention of radiation-induced salivary gland dysfunction in head and neck cancer patients.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2015, Volume: 115, Issue:2

    Topics: Adult; Aged; Bethanechol; Dose-Response Relationship, Radiation; Double-Blind Method; Female; Head a

2015
The efficacy of pilocarpine and bethanechol upon saliva production in cancer patients with hyposalivation following radiation therapy.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2004, Volume: 97, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Attitude to Health; Bethanechol; Cross-Over Studies; Female; Head an

2004
A randomized phase III prospective trial of bethanechol to prevent radiotherapy-induced salivary gland damage in patients with head and neck cancer.
    Oral oncology, 2007, Volume: 43, Issue:2

    Topics: Adult; Aged; Bethanechol; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Stagi

2007
A clinical trial of bethanechol in patients with xerostomia after radiation therapy. A pilot study.
    Oral surgery, oral medicine, and oral pathology, 1994, Volume: 77, Issue:6

    Topics: Bethanechol; Bethanechol Compounds; Carcinoma, Squamous Cell; Cranial Irradiation; Female; Head and

1994

Other Studies

4 other studies available for bethanechol and Asialia

ArticleYear
Influence of bethanechol on salivary parameters in irradiated patients.
    Medicina oral, patologia oral y cirugia bucal, 2017, Jan-01, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Aged; Bethanechol; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Ra

2017
Oral transmucosal fentanyl citrate and xerostomia.
    Journal of pain and symptom management, 2005, Volume: 30, Issue:6

    Topics: Administration, Buccal; Analgesics, Opioid; Back Pain; Bethanechol; Colonic Neoplasms; Drug Combinat

2005
Another explanation for urinary tract problems in schizophrenic patients.
    The American journal of psychiatry, 1984, Volume: 141, Issue:4

    Topics: Antiparkinson Agents; Bethanechol; Bethanechol Compounds; Drinking Behavior; Humans; Hydronephrosis;

1984
Pirenzepine and propantheline effects on esophageal pressure responses to bethanechol.
    The American journal of gastroenterology, 1986, Volume: 81, Issue:5

    Topics: Adult; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Esophagus; Female; Gastrointestinal Ag

1986
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