bethanechol has been researched along with Alloxan Diabetes in 13 studies
Bethanechol: A slowly hydrolyzing muscarinic agonist with no nicotinic effects. Bethanechol is generally used to increase smooth muscle tone, as in the GI tract following abdominal surgery or in urinary retention in the absence of obstruction. It may cause hypotension, HEART RATE changes, and BRONCHIAL SPASM.
bethanechol : The carbamic acid ester of 2-methylcholine. A slowly hydrolysed muscarinic agonist with no nicotinic effects, it is used as its chloride salt to increase smooth muscle tone, as in the gastrointestinal tract following abdominal surgery, treatment of gastro-oesophageal reflux disease, and as an alternative to catheterisation in the treatment of non-obstructive urinary retention.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alloxan (100 mg/kg) was administered intravenously into the ear vein, and the blood glucose levels were estimated weekly for a duration of 2 months." | 1.29 | Vascular responses to norepinephrine and bethanechol in isolated aortae from 2-month diabetic rabbits induced by alloxan. ( Wong, KK, 1996) |
| " Dose-response studies of intestinal muscle after 3 mo of untreated diabetes showed normal tension development to both bethanechol chloride and physostigmine." | 1.28 | Adaptation of cholinergic enteric neuromuscular transmission in diabetic rat small intestine. ( Harrington, B; Kalbfleisch, J; Nowak, TV, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (23.08) | 18.7374 |
| 1990's | 8 (61.54) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lautt, WW | 1 |
| Schafer, J | 1 |
| Macedo, MP | 1 |
| Legare, DJ | 1 |
| James, AN | 1 |
| Ryan, JP | 1 |
| Crowell, MD | 1 |
| Parkman, HP | 1 |
| Wong, KK | 3 |
| Longhurst, PA | 1 |
| Briscoe, JA | 1 |
| Leggett, RE | 1 |
| Samadzadeh, S | 1 |
| Levin, RM | 1 |
| Hung, CR | 1 |
| Tzeng, SF | 1 |
| Tamada, J | 1 |
| Langer, R | 1 |
| Mantle, M | 1 |
| Thakore, E | 1 |
| Mathison, R | 2 |
| Davison, JS | 2 |
| Nowak, TV | 1 |
| Harrington, B | 1 |
| Kalbfleisch, J | 1 |
| Kudlacz, EM | 1 |
| Gerald, MC | 1 |
| Wallace, LJ | 1 |
| Aronstam, RS | 1 |
| Carrier, GO | 1 |
1 review available for bethanechol and Alloxan Diabetes
| Article | Year |
|---|---|
The development of polyanhydrides for drug delivery applications.
Topics: Alzheimer Disease; Anhydrides; Animals; Bethanechol; Bethanechol Compounds; Biocompatible Materials; | 1992 |
1 trial available for bethanechol and Alloxan Diabetes
| Article | Year |
|---|---|
The development of polyanhydrides for drug delivery applications.
Topics: Alzheimer Disease; Anhydrides; Animals; Bethanechol; Bethanechol Compounds; Biocompatible Materials; | 1992 |
12 other studies available for bethanechol and Alloxan Diabetes
| Article | Year |
|---|---|
Bethanechol and N-acetylcysteine mimic feeding signals and reverse insulin resistance in fasted and sucrose-induced diabetic rats.
Topics: Acetylcysteine; Animals; Bethanechol; Biomimetic Materials; Diabetes Mellitus, Experimental; Fasting | 2011 |
Regional gastric contractility alterations in a diabetic gastroparesis mouse model: effects of cholinergic and serotoninergic stimulation.
Topics: Animals; Bethanechol; Cholinergic Agonists; Diabetes Mellitus, Experimental; Dose-Response Relations | 2004 |
Cardiac response to autonomic drugs in atria of diabetic mouse.
Topics: 1-Methyl-3-isobutylxanthine; Alloxan; Animals; Bethanechol; Blood Glucose; Diabetes Mellitus, Experi | 1994 |
The influence of diabetes mellitus on glucose utilization by the rat urinary bladder.
Topics: Adenosine Triphosphate; Animals; Bethanechol; Bethanechol Compounds; Body Weight; Chromatography, Hi | 1993 |
Vascular responses to norepinephrine and bethanechol in isolated aortae from 2-month diabetic rabbits induced by alloxan.
Topics: Alloxan; Animals; Aorta; Bethanechol; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Angio | 1996 |
Low susceptibility of stress ulcer in diabetic rats: role of cholinergic gastric motility.
Topics: Animals; Antiemetics; Antimetabolites; Atropine; Bethanechol; Blood Glucose; Body Weight; Cholinergi | 1998 |
Norepinephrine-induced contractile responses in isolated rat aortae from different duration of diabetes.
Topics: Animals; Aorta, Thoracic; Bethanechol; Bethanechol Compounds; Diabetes Mellitus, Experimental; Dose- | 1992 |
Intestinal mucin secretion in streptozotocin-diabetic rats: lack of response to cholinergic stimulation and cholera toxin.
Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Cholera Toxin; Diabetes Mellitus, Experimenta | 1991 |
Adaptation of cholinergic enteric neuromuscular transmission in diabetic rat small intestine.
Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Cholinergic Fibers; Diabetes Mellitus, Experi | 1990 |
Effects of diabetes and diuresis on contraction and relaxation mechanisms in rat urinary bladder.
Topics: Aminophylline; Animals; Bethanechol; Bethanechol Compounds; Choline O-Acetyltransferase; Diabetes Me | 1989 |
Insulin prevention of altered muscarinic receptor-G protein coupling in diabetic rat atria.
Topics: Acetylcholine; Animals; Bethanechol; Bethanechol Compounds; Carbachol; Diabetes Mellitus, Experiment | 1989 |
Modified smooth muscle responses of jejunum in streptozotocin-diabetic rats.
Topics: Animals; Bethanechol; Bethanechol Compounds; Bradykinin; Diabetes Mellitus, Experimental; Jejunum; M | 1988 |