Page last updated: 2024-10-23

betaxolol and Glaucoma

betaxolol has been researched along with Glaucoma in 101 studies

Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)

Research Excerpts

ExcerptRelevanceReference
"To describe the safety profile and clinical response on elevated intraocular pressure (IOP) of betaxolol hydrochloride ophthalmic suspension 0."9.14Betaxolol hydrochloride ophthalmic suspension 0.25% and timolol gel-forming solution 0.25% and 0.5% in pediatric glaucoma: a randomized clinical trial. ( Dickerson, JE; Gross, RD; Krishnadas, SR; Netland, PA; Plager, DA; Robin, AL; Sathyan, P; Scheib, SA; Scott, H; Sood, D; Vijaya, L; Whitson, JT, 2009)
"To describe the safety and clinical response on elevated intraocular pressure (IOP) of brinzolamide and levobetaxolol in pediatric patients under 6 years of age."9.13Efficacy of brinzolamide and levobetaxolol in pediatric glaucomas: a randomized clinical trial. ( Bergamini, MV; Dickerson, JE; Gross, RD; Hua, SY; Landry, TA; Roarty, JD; Robin, AL; Scheib, SA; Scott, H; Vijaya, L; Whitson, JT; Woodside, AM, 2008)
"To determine whether treatment with betaxolol can delay or prevent the conversion from ocular hypertension to early glaucoma on the basis of visual field criteria, by means of a prospective, randomised, placebo-controlled trial."9.10Results of the betaxolol versus placebo treatment trial in ocular hypertension. ( Bunce, C; Franks, W; Garway-Heath, D; Hitchings, R; Kamal, D; O'Sullivan, F; Ruben, S; Viswanathan, A, 2003)
"We compared the effect of selective (betaxolol) and nonselective (timolol) beta-adrenergic blocking drugs on flow velocities (as determined by color Doppler imaging) in orbital vessels in 13 patients with normal-tension glaucoma (mean age, 62 +/- 3 years; mean intraocular pressure, 15 +/- 2 mm Hg)."9.08Retrobulbar arterial hemodynamic effects of betaxolol and timolol in normal-tension glaucoma. ( Cantor, LB; Harris, A; Katz, LJ; Martin, BJ; Sergott, RC; Spaeth, GL, 1995)
"In a double-masked study, 40 patients with primary open-angle glaucoma were randomly assigned to treatment with betaxolol 0."9.07Influence of betaxolol and timolol on the visual fields of patients with glaucoma. ( Flammer, J; Messmer, C; Stümpfig, D, 1991)
"The extent of impairment of respiratory function in a group of 52 elderly, glaucomatous patients receiving topical timolol therapy was investigated."9.07Unsuspected bronchospasm in association with topical timolol--a common problem in elderly people: can we easily identify those affected and do cardioselective agents lead to improvement? ( Chau, G; Diggory, P; Heyworth, P; McKenzie, S; Sharma, A, 1994)
"Betaxolol, a cardioselective beta 1-adrenergic antagonist, was used in a clinical trial in nine patients with glaucoma and chronic obstructive airways disease to assess its patient acceptance, and its effect on intraocular pressure, respiratory function, corneal and tear function."9.06Betaxolol eye drops as a safe medication to lower intraocular pressure. ( Brooks, AM; Gillies, WE; West, RH, 1987)
"In a randomized, double-masked study, 41 patients with primary open-angle glaucoma or ocular hypertension were treated with betaxolol 0."9.06A comparison of betaxolol and timolol in open angle glaucoma and ocular hypertension. ( Feghali, JG; Kaufman, PL; Mandell, AI; Radius, RL, 1988)
"Betaxolol is a new antiglaucomatous drug which is blocking solely the beta 1 receptors and in contrast to Timolol may be applied in persons with spastic conditions of the bronchi."9.06[Use of Betaxolol in patients with glaucoma and chronic nonspecific diseases of the respiratory system]. ( Rojek, A; Sempińska-Szewczyk, J; Swietliczko, I; Toczyska-Rozentryt, E, 1989)
"Three hundred fifty-three patients whose intraocular pressure was controlled with a timolol maleate ophthalmic solution were studied."9.06Changing therapy from timolol to betaxolol. Effect on intraocular pressure in selected patients with glaucoma. Timolol-Betaxolol Study Group. ( Clineschmidt, CM; Kulaga, SF; Tipping, R; Vogel, R, 1989)
"To report a case of pulmonary edema associated with the use of ocular metipranolol, a nonselective beta-blocker."8.79Acute pulmonary edema associated with ocular metipranolol use. ( Johns, MD; Ponte, CD, 1995)
", niosomes) as drug vehicles to enhance the ocular availability of betaxolol hydrochloride for management of glaucoma."8.02Betaxolol-loaded niosomes integrated within pH-sensitive in situ forming gel for management of glaucoma. ( Allam, A; El Badry, M; Eleraky, NE; Elsabahy, M, 2021)
"The purpose of the study was to evaluate influence of betaxolol, brimonidine and carteolol in the progression of the visual field defects during time at patients with normotensive glaucoma (NTG)."7.96Betaxolol, Brimonidin and Carteolol in the Therapy of Normal-Tension Glaucoma. ( Fůs, M; Lešták, J; Marešová, K; Weissová, I, 2020)
"Inspired by these advance of montmorillonite/chitosan nanoparticles, we envision that the BH-Mt/CS NPs will be a potential carrier for BH, opening up the possible applications in glaucoma therapy."7.88Montmorillonite/chitosan nanoparticles as a novel controlled-release topical ophthalmic delivery system for the treatment of glaucoma. ( Chen, Y; Gui, R; Hou, D; Li, J; Ping, Q; Tao, Q; Tian, S; Yang, F; Zang, L; Zhao, Y, 2018)
"Enucleated eyes (n = 7) of patients with glaucoma (age range, 27-79 years), without apparent anatomic disruption that would be likely to influence betaxolol absorption and intraocular distribution (exceptions: one pseudophakic, one aphakic) or other disease, were analyzed for betaxolol concentrations after self-administration of 0."7.73Concentrations of betaxolol in ocular tissues of patients with glaucoma and normal monkeys after 1 month of topical ocular administration. ( Chastain, J; Curtis, M; Dahlin, DC; DeSantis, L; Faulkner, R; Holló, G; McCue, B; Przydryga, J; Sanders, M; Whitson, JT; Wieland, H, 2006)
"To evaluate the intraocular pressure (IOP) lowering efficacy and safety of Brinzolamide combined with Betaxolol for the Chinese glaucomatous patients."7.73[Clinical investigation: the intraocular pressure-lowering efficacy and safety of brinzolamide combined with betaxolol]. ( Fang, M; Ge, J; Huang, S; Minbin, Y, 2005)
"To report a case of herpes simplex virus reactivation after starting bimatoprost treatment for glaucoma."7.71Reactivation of herpes simplex virus keratitis after initiating bimatoprost treatment for glaucoma. ( Kroll, DM; Schuman, JS, 2002)
"Small (1-cc) specimens of Tenon capsule were removed at the time of filtering surgery from 15 glaucoma patients under long-term preoperative topical therapy, nine of whom had been treated with timolol and six of whom had been receiving betaxolol."7.70Periocular accumulation of timolol and betaxolol in glaucoma patients under long-term therapy. ( Frenzel, H; Khuu, HD; Lam, KW; Sponsel, WE; Terry, S, 1999)
"We evaluated the use of topically administered betaxolol, a cardioselective beta-adrenergic blocking agent, in 11 patients (eight women and three men, 40 to 81 years old) who had asthma and severe glaucoma with increased intraocular pressure despite maximally tolerated medical therapy."7.67Betaxolol in patients with glaucoma and asthma. ( Berry, DP; Drake, MM; Lustgarten, JS; Podos, SM; Van Buskirk, EM; Weinreb, RN, 1986)
"Glaucoma is a chronic optic neuropathy in which retinal ganglion cells die over a number of years."6.42Effectiveness of levobetaxolol and timolol at blunting retinal ischaemia is related to their calcium and sodium blocking activities: relevance to glaucoma. ( Casson, R; Chidlow, G; DeSantis, L; Osborne, NN; Schmidt, KG; Wood, JP, 2004)
"Betaxolol is a lipophilic beta-adrenoceptor antagonist relatively selective for beta 1-adrenoceptors with only weak beta 2-blocking activity."6.38Ocular betaxolol. A review of its pharmacological properties, and therapeutic efficacy in glaucoma and ocular hypertension. ( Buckley, MM; Clissold, SP; Goa, KL, 1990)
"Glaucoma is described, and the chemistry, pharmacology, pharmacokinetics, clinical efficacy, adverse effects, and dosage and administration of betaxolol and levobunolol in comparison with timolol are reviewed."6.16Comparison of ophthalmic beta-blocking agents. ( Lesar, TS, 1987)
"Glaucoma is a chronic disease that requires long-term adherence to treatment."5.72Critical Evaluation of Multifunctional Betaxolol Hydrochloride Nanoformulations for Effective Sustained Intraocular Pressure Reduction. ( Han, X; Hou, D; Hu, J; Ke, Y; Li, H; Li, W; Lin, H; Liu, H; Rupenthal, ID; Yang, F; Ye, J; Zhao, Y, 2022)
"In a double masked randomised clinical trial, 38 eyes from 38 pseudophakic patients over 21 years of age who had significant posterior capsule opacification after phacoemulsification were randomly assigned to receive either betaxolol 0."5.51The prophylactic effect of betaxolol 0.5% versus brimonidine 0.2% on IOP elevation after Nd:YAG laser posterior capsulotomy. ( Elmi Sadr, N; Paknazar, F; Saber, E, 2022)
"Our aim was to study the concentration of betaxolol in plasma after its topical ocular use during the normal 12 hr dosing interval."5.31Plasma concentration of topically applied betaxolol in elderly glaucoma patients. ( Huupponen, R; Pyykkö, K; Vainio-Jylhä, E; Vuori, ML, 2001)
"To investigate the acute effects of brinzolamide, betaxolol, and latanoprost (drugs commonly used in the medical management of glaucoma) on choroidal thickness using enhanced depth imaging optical coherence tomography (EDI-OCT)."5.30Direct and crossover effects of brinzolamide, betaxolol, and latanoprost on choroidal thickness. ( Arslan, MG; Fındık, H; Okutucu, M, 2019)
" Very mild eye irritation, which was less than that of betaxolol hydrochloride, was observed particularly with BMO maleate, which is an excellent candidate for safe treatment of glaucoma."5.30Ocular-specific chemical delivery systems of betaxolol for safe local treatment of glaucoma. ( Barros, MD; Bodor, N; Farag, HH; Prokai, L; Somogyi, G; Wu, WM, 1997)
"Betaxolol 0."5.27Long-term betaxolol therapy in glaucoma patients with pulmonary disease. ( Cherniack, R; Drake, MM; van Buskirk, EM; Weinreb, RN, 1988)
"To describe the safety profile and clinical response on elevated intraocular pressure (IOP) of betaxolol hydrochloride ophthalmic suspension 0."5.14Betaxolol hydrochloride ophthalmic suspension 0.25% and timolol gel-forming solution 0.25% and 0.5% in pediatric glaucoma: a randomized clinical trial. ( Dickerson, JE; Gross, RD; Krishnadas, SR; Netland, PA; Plager, DA; Robin, AL; Sathyan, P; Scheib, SA; Scott, H; Sood, D; Vijaya, L; Whitson, JT, 2009)
"To describe the safety and clinical response on elevated intraocular pressure (IOP) of brinzolamide and levobetaxolol in pediatric patients under 6 years of age."5.13Efficacy of brinzolamide and levobetaxolol in pediatric glaucomas: a randomized clinical trial. ( Bergamini, MV; Dickerson, JE; Gross, RD; Hua, SY; Landry, TA; Roarty, JD; Robin, AL; Scheib, SA; Scott, H; Vijaya, L; Whitson, JT; Woodside, AM, 2008)
"To determine whether treatment with betaxolol can delay or prevent the conversion from ocular hypertension to early glaucoma on the basis of visual field criteria, by means of a prospective, randomised, placebo-controlled trial."5.10Results of the betaxolol versus placebo treatment trial in ocular hypertension. ( Bunce, C; Franks, W; Garway-Heath, D; Hitchings, R; Kamal, D; O'Sullivan, F; Ruben, S; Viswanathan, A, 2003)
" In a double-masked fashion, each subject's right eye was treated with one of 5 glaucoma medications (brinzolamide 1%, timolol 0."5.09Does glaucoma medication influence the diameter of the retinal arteriole in the human eye? (A pilot study using the retinal vessel analyser). ( Holló, G; Kóthy, P, 2001)
"We compared the effect of selective (betaxolol) and nonselective (timolol) beta-adrenergic blocking drugs on flow velocities (as determined by color Doppler imaging) in orbital vessels in 13 patients with normal-tension glaucoma (mean age, 62 +/- 3 years; mean intraocular pressure, 15 +/- 2 mm Hg)."5.08Retrobulbar arterial hemodynamic effects of betaxolol and timolol in normal-tension glaucoma. ( Cantor, LB; Harris, A; Katz, LJ; Martin, BJ; Sergott, RC; Spaeth, GL, 1995)
"The extent of impairment of respiratory function in a group of 52 elderly, glaucomatous patients receiving topical timolol therapy was investigated."5.07Unsuspected bronchospasm in association with topical timolol--a common problem in elderly people: can we easily identify those affected and do cardioselective agents lead to improvement? ( Chau, G; Diggory, P; Heyworth, P; McKenzie, S; Sharma, A, 1994)
"Fifty-two elderly glaucomatous patients, without a history of asthma or obstructive airways disease, who were using topical timolol for control of intraocular pressure were recruited."5.07Improved lung function tests on changing from topical timolol: non-selective beta-blockade impairs lung function tests in elderly patients. ( Chau, G; Diggory, P; Heyworth, P; Luke, I; McKenzie, S; Sharma, A, 1993)
"In a double-masked study, 40 patients with primary open-angle glaucoma were randomly assigned to treatment with betaxolol 0."5.07Influence of betaxolol and timolol on the visual fields of patients with glaucoma. ( Flammer, J; Messmer, C; Stümpfig, D, 1991)
"A double-blind cross-over study was carried out on 15 glaucoma patients so as to verify the effects of three the beta blockers, beta-1 selective betaxolol, non-selective timolol and befunolol an agent with intrinsic sympathomimetic activity on the heart rate, monitored by a Holter apparatus, and with the blood pressure measured in standing and supine positions before and after eight days of topical therapy."5.06Cardiovascular effects of befunolol, betaxolol and timolol eye drops. ( Altafini, R; Cerin, O; Dorigo, MT; Fracasso, G, 1990)
"Betaxolol is a new antiglaucomatous drug which is blocking solely the beta 1 receptors and in contrast to Timolol may be applied in persons with spastic conditions of the bronchi."5.06[Use of Betaxolol in patients with glaucoma and chronic nonspecific diseases of the respiratory system]. ( Rojek, A; Sempińska-Szewczyk, J; Swietliczko, I; Toczyska-Rozentryt, E, 1989)
"Betaxolol, a cardioselective beta 1-adrenergic antagonist, was used in a clinical trial in nine patients with glaucoma and chronic obstructive airways disease to assess its patient acceptance, and its effect on intraocular pressure, respiratory function, corneal and tear function."5.06Betaxolol eye drops as a safe medication to lower intraocular pressure. ( Brooks, AM; Gillies, WE; West, RH, 1987)
"In a randomized, double-masked study, 41 patients with primary open-angle glaucoma or ocular hypertension were treated with betaxolol 0."5.06A comparison of betaxolol and timolol in open angle glaucoma and ocular hypertension. ( Feghali, JG; Kaufman, PL; Mandell, AI; Radius, RL, 1988)
"To report a case of pulmonary edema associated with the use of ocular metipranolol, a nonselective beta-blocker."4.79Acute pulmonary edema associated with ocular metipranolol use. ( Johns, MD; Ponte, CD, 1995)
" Betaxolol is a relatively selective beta-1 blocker which in most patients is almost as effective as timolol in lowering intraocular pressure, and may be partly additive with dipivefrin."4.77Betaxolol. ( Goldberg, I, 1989)
"The purpose of the study was to evaluate influence of betaxolol, brimonidine and carteolol in the progression of the visual field defects during time at patients with normotensive glaucoma (NTG)."3.96Betaxolol, Brimonidin and Carteolol in the Therapy of Normal-Tension Glaucoma. ( Fůs, M; Lešták, J; Marešová, K; Weissová, I, 2020)
"Inspired by these advance of montmorillonite/chitosan nanoparticles, we envision that the BH-Mt/CS NPs will be a potential carrier for BH, opening up the possible applications in glaucoma therapy."3.88Montmorillonite/chitosan nanoparticles as a novel controlled-release topical ophthalmic delivery system for the treatment of glaucoma. ( Chen, Y; Gui, R; Hou, D; Li, J; Ping, Q; Tao, Q; Tian, S; Yang, F; Zang, L; Zhao, Y, 2018)
"In this study, the various antiglaucoma drugs including betaxolol, timolol, levobunolol, carteolol, brimonidine, dipivefrin, dorzolamide, brinzolamide, latanoprost, unoprostone, and pilocarpine were used to investigate the effects of cellular cytotoxicity in cultured bovine corneal endothelial cells."3.74Cellular cytotoxicity of antiglaucoma drugs in cultured corneal endothelial cells. ( Hong, SJ; Wang, HZ; Wu, KY, 2007)
"In the present study, we investigated the direct effects of antiglaucoma drugs (timolol, betaxolol, pilocarpine, and latanoprost) on N-methyl-D-aspartate (NMDA)-receptor function using a Xenopus oocytes expression system and electrophysiological techniques."3.74Direct inhibition of N-methyl-D-aspartate (NMDA)-receptor function by antiglaucomatous beta-antagonists. ( Kubota, T; Morita, H; Nagata, T; Tawara, A; Toyohira, Y; Tsutsui, M; Ueno, S; Yanagihara, N, 2008)
"Enucleated eyes (n = 7) of patients with glaucoma (age range, 27-79 years), without apparent anatomic disruption that would be likely to influence betaxolol absorption and intraocular distribution (exceptions: one pseudophakic, one aphakic) or other disease, were analyzed for betaxolol concentrations after self-administration of 0."3.73Concentrations of betaxolol in ocular tissues of patients with glaucoma and normal monkeys after 1 month of topical ocular administration. ( Chastain, J; Curtis, M; Dahlin, DC; DeSantis, L; Faulkner, R; Holló, G; McCue, B; Przydryga, J; Sanders, M; Whitson, JT; Wieland, H, 2006)
"The aim of this study was to estimate the effects of various antiglaucoma drugs including betaxolol, timolol, levobunolol, brimonidine, carteolol, dipivefrin, dorzolamide, brinzolamide, latanoprost, unoprostone, and pilocarpine on intracellular free Ca2+ ([Ca2+]i) mobility in cultured bovine corneal endothelial cells."3.73Effects of antiglaucoma drugs on calcium mobility in cultured corneal endothelial cells. ( Hong, SJ; Wang, HZ; Wu, KY, 2006)
"To evaluate the intraocular pressure (IOP) lowering efficacy and safety of Brinzolamide combined with Betaxolol for the Chinese glaucomatous patients."3.73[Clinical investigation: the intraocular pressure-lowering efficacy and safety of brinzolamide combined with betaxolol]. ( Fang, M; Ge, J; Huang, S; Minbin, Y, 2005)
" In the present study, we investigated various commercial antiglaucoma drugs including timolol (0."3.72Effects of commercial antiglaucoma drugs to glutamate-induced [Ca2+)]i increase in cultured neuroblastoma cells. ( Fong, JC; Hong, SJ; Wang, HZ; Wu, KY, 2003)
"Claims databases administered by the Régie de l'assurance maladie du Quebec were used to identify incident users of beta-blockers (betaxolol and timolol) and newer antiglaucoma agents (brimonidine, dorzolamide and latanoprost) among patients aged 35 years or older."3.72Prescription of topical antiglaucoma agents for patients with contraindications to beta-blockers. ( Assalian, A; Castilloux, AM; Houde, M; LeLorier, J; Tingey, D, 2003)
"To report a case of herpes simplex virus reactivation after starting bimatoprost treatment for glaucoma."3.71Reactivation of herpes simplex virus keratitis after initiating bimatoprost treatment for glaucoma. ( Kroll, DM; Schuman, JS, 2002)
"Of the antiglaucoma drugs investigated, betaxolol displays the greatest L-type VDCC-blocking activity and this may be of clinical relevance."3.71Comparative effects of antiglaucoma drugs on voltage-dependent calcium channels. ( Melena, J; Osborne, NN; Stanton, D, 2001)
"We evaluated the effect of betaxolol on the pulmonary function tests of nine patients with glaucoma and chronic obstructive pulmonary disease (COPD) requiring beta-blocker therapy."3.67Betaxolol in chronic obstructive pulmonary disease. ( Ofner, S; Smith, TJ, 1987)
"We evaluated the use of topically administered betaxolol, a cardioselective beta-adrenergic blocking agent, in 11 patients (eight women and three men, 40 to 81 years old) who had asthma and severe glaucoma with increased intraocular pressure despite maximally tolerated medical therapy."3.67Betaxolol in patients with glaucoma and asthma. ( Berry, DP; Drake, MM; Lustgarten, JS; Podos, SM; Van Buskirk, EM; Weinreb, RN, 1986)
"Four hundred sixteen subjects with ocular hypertension (intraocular pressure >/=22 and 2.75The ability of short-wavelength automated perimetry to predict conversion to glaucoma. ( Colen, TP; Lemij, HG; Reus, NJ; van der Schoot, J, 2010)
"Glaucoma is a chronic optic neuropathy in which retinal ganglion cells die over a number of years."2.42Effectiveness of levobetaxolol and timolol at blunting retinal ischaemia is related to their calcium and sodium blocking activities: relevance to glaucoma. ( Casson, R; Chidlow, G; DeSantis, L; Osborne, NN; Schmidt, KG; Wood, JP, 2004)
"2% for chronic use in patients with ocular hypertension and glaucoma."2.40Brimonidine: a new alpha2-adrenoreceptor agonist for glaucoma treatment. ( Greenfield, DS; Liebmann, JM; Ritch, R, 1997)
"Betaxolol is a lipophilic beta-adrenoceptor antagonist relatively selective for beta 1-adrenoceptors with only weak beta 2-blocking activity."2.38Ocular betaxolol. A review of its pharmacological properties, and therapeutic efficacy in glaucoma and ocular hypertension. ( Buckley, MM; Clissold, SP; Goa, KL, 1990)
"Glaucoma is a group of eye diseases consisting of optic nerve damage with corresponding loss of field vision and blindness."1.72Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H ( Andreozzi, G; Calderone, V; Caliendo, G; Citi, V; Corvino, A; Fiorino, F; Frecentese, F; Magli, E; Martelli, A; Perissutti, E; Piragine, E; Santagada, V; Severino, B; Sparaco, R, 2022)
"Glaucoma is a chronic disease that requires long-term adherence to treatment."1.72Critical Evaluation of Multifunctional Betaxolol Hydrochloride Nanoformulations for Effective Sustained Intraocular Pressure Reduction. ( Han, X; Hou, D; Hu, J; Ke, Y; Li, H; Li, W; Lin, H; Liu, H; Rupenthal, ID; Yang, F; Ye, J; Zhao, Y, 2022)
"Glaucoma is a serious eye disease that can lead to loss of vision."1.48Controlled drug delivery for glaucoma therapy using montmorillonite/Eudragit microspheres as an ion-exchange carrier. ( Chen, Y; Duan, H; Hou, D; Li, J; Lv, Z; Tao, Q; Tian, S; Yang, F; Zhao, Y; Zhou, Q, 2018)
"Betaxolol was twice as effective at preventing the effect of IgG (34% to 37%) than that of zymosan (14%), regardless of the presence of BAK."1.32In vitro effects of preserved or preservative-free antiglaucoma medications on human complement system. ( Baudouin, C; Blondin, C; Cholley, B; Haeffner-Cavaillon, N; Hamard, P, 2003)
"Twenty-nine of these were treated for glaucoma and eight followed for ocular hypertension without treatment."1.30Five-year follow-up of treated patients with glaucoma using resolution perimetry. ( Martin, L; Wanger, P, 1998)
" Very mild eye irritation, which was less than that of betaxolol hydrochloride, was observed particularly with BMO maleate, which is an excellent candidate for safe treatment of glaucoma."1.30Ocular-specific chemical delivery systems of betaxolol for safe local treatment of glaucoma. ( Barros, MD; Bodor, N; Farag, HH; Prokai, L; Somogyi, G; Wu, WM, 1997)
"In 35 of the 56 treated glaucoma patients the thresholds improved more than 0."1.29The effect of treatment on the results of high-pass resolution perimetry in glaucoma. ( Martin-Boglind, L; Wanger, P, 1994)
"While adverse effects are uncommon in patients who are otherwise fit and well, doctors should be aware of the implications of the systemic effects of these drugs, particularly the non-selective types, and particularly in the elderly."1.29The safety of topical beta-blockers in glaucoma treatment. ( Goldberg, I, 1996)
" This new pharmaceutical dosage form produces very interesting therapeutic effects with much lower drug concentrations than that commonly used in aqueous commercial eye drops; thus, systemic and local side effects could be minimized."1.28[Nanocapsules of beta-blocking agents: a new drug carrier in ophthalmology. Application to medical treatment of glaucoma in rabbits]. ( Hoffman, M; Maincent, P; Marchal-Heussler, L; Sirbat, D, 1991)
"Betaxolol 0."1.27Long-term betaxolol therapy in glaucoma patients with pulmonary disease. ( Cherniack, R; Drake, MM; van Buskirk, EM; Weinreb, RN, 1988)

Research

Studies (101)

TimeframeStudies, this research(%)All Research%
pre-199028 (27.72)18.7374
1990's29 (28.71)18.2507
2000's31 (30.69)29.6817
2010's8 (7.92)24.3611
2020's5 (4.95)2.80

Authors

AuthorsStudies
Sugrue, MF1
Elmi Sadr, N1
Saber, E1
Paknazar, F1
Sparaco, R3
Citi, V3
Magli, E3
Martelli, A3
Piragine, E3
Calderone, V3
Andreozzi, G3
Perissutti, E3
Frecentese, F3
Santagada, V3
Caliendo, G3
Severino, B3
Corvino, A3
Fiorino, F3
Hu, J2
Li, H2
Zhao, Y4
Ke, Y2
Rupenthal, ID2
Liu, H2
Ye, J2
Han, X2
Yang, F4
Li, W2
Lin, H2
Hou, D4
Lešták, J1
Fůs, M1
Weissová, I1
Marešová, K1
Allam, A1
Elsabahy, M1
El Badry, M1
Eleraky, NE1
Tian, S2
Li, J2
Tao, Q2
Lv, Z1
Duan, H1
Chen, Y2
Zhou, Q1
Gui, R1
Zang, L1
Ping, Q1
Okutucu, M1
Fındık, H1
Arslan, MG1
Jain, K1
Kumar, RS1
Sood, S1
Dhyanandhan, G1
Fukuchi, T1
Kuprjanowicz, L1
Karczewicz, D1
Plager, DA1
Whitson, JT4
Netland, PA1
Vijaya, L2
Sathyan, P1
Sood, D1
Krishnadas, SR1
Robin, AL2
Gross, RD2
Scheib, SA2
Scott, H2
Dickerson, JE2
Grieshaber, MC1
Flammer, J3
van der Schoot, J1
Reus, NJ1
Colen, TP1
Lemij, HG1
Rahman, MQ1
Abeysinghe, SS1
Kelly, S1
Roskell, NS1
Shannon, PR1
Abdlseaed, AA1
Montgomery, DM1
Kóthy, P1
Holló, G3
Vainio-Jylhä, E2
Vuori, ML2
Nummelin, K1
Kamal, D1
Garway-Heath, D1
Ruben, S1
O'Sullivan, F1
Bunce, C1
Viswanathan, A1
Franks, W1
Hitchings, R1
Lin, JC1
Samuel, F1
Katz, LJ2
Spaeth, GL2
Hoop, J1
Cantor, LB2
Hong, SJ4
Wu, KY4
Wang, HZ4
Fong, JC1
Blondin, C1
Hamard, P1
Cholley, B1
Haeffner-Cavaillon, N1
Baudouin, C1
Houde, M1
Castilloux, AM1
Tingey, D1
Assalian, A1
LeLorier, J1
Leske, MC1
Heijl, A1
Hyman, L1
Bengtsson, B1
Komaroff, E1
Osborne, NN2
Wood, JP1
Chidlow, G1
Casson, R1
DeSantis, L2
Schmidt, KG1
Yarangümeli, A1
Kural, G1
Ignat, F1
Turaçli, ME1
Tekeli, O1
Erb, C1
Schröder, H1
Faulkner, R1
McCue, B1
Curtis, M1
Wieland, H1
Chastain, J1
Sanders, M1
Przydryga, J1
Dahlin, DC1
Minbin, Y1
Fang, M1
Ge, J1
Huang, S1
Easton, PJ1
Roarty, JD1
Landry, TA1
Hua, SY1
Woodside, AM1
Bergamini, MV1
Nagata, T1
Ueno, S1
Morita, H1
Kubota, T1
Toyohira, Y1
Tsutsui, M1
Tawara, A1
Yanagihara, N1
Harrison, R1
Remis, LL1
Epstein, DL2
Johns, MD1
Ponte, CD1
Harris, A1
Sergott, RC1
Martin, BJ1
Martin-Boglind, L1
Wanger, P3
Zimmerman, TJ1
Frishman, WH1
Fuksbrumer, MS1
Tannenbaum, M1
Diggory, P3
Heyworth, P2
Chau, G2
McKenzie, S2
Sharma, A2
O'Donnell, BF1
Foulds, IS1
Nyman, K1
Luke, I1
Goldberg, I2
Gale, AE1
Gillies, WE2
Brooks, AM2
Greenfield, DS1
Liebmann, JM1
Ritch, R1
Farag, HH1
Wu, WM1
Barros, MD1
Somogyi, G1
Prokai, L1
Bodor, N1
Martin, L1
Morrison, JC1
Nylander, KB1
Lauer, AK1
Cepurna, WO1
Johnson, E1
Cassels-Brown, A1
Vail, A1
Hillman, JS1
Collignon-Brach, J1
Demailly, P1
Graves, SA1
Wolfhagen, FH1
van Neerven, JA1
Groen, FC1
Ouwendijk, RJ1
Sponsel, WE1
Terry, S1
Khuu, HD1
Lam, KW1
Frenzel, H1
Waldock, A1
Snape, J1
Graham, CM1
Pyykkö, K1
Huupponen, R1
Melena, J1
Stanton, D1
Schweitzer, I1
Maguire, K1
Tuckwell, V1
Grehn, F1
Kroll, DM1
Schuman, JS1
Potocký, M1
Vodrázková, E1
Duch, S1
Duch, C1
Pastó, L1
Ferrer, P1
Marchal-Heussler, L1
Sirbat, D1
Hoffman, M1
Maincent, P1
Messmer, C1
Stümpfig, D1
Dorigo, MT1
Cerin, O1
Fracasso, G1
Altafini, R1
Martin-Boglind, LM1
Graves, A1
Buckley, MM1
Goa, KL1
Clissold, SP1
Collignon, P1
James, IM1
Pillunat, LE2
Stodtmeister, R2
Vogel, R1
Tipping, R1
Kulaga, SF1
Clineschmidt, CM1
Swietliczko, I1
Rojek, A1
Sempińska-Szewczyk, J1
Toczyska-Rozentryt, E1
Soll, DB1
Saxon, AM1
Richards, RD1
Nelson, WL1
Kuritsky, JN1
Berger, WE1
West, RH1
Lesar, TS1
Tierney, DW1
Thygesen, J1
Feghali, JG1
Kaufman, PL1
Radius, RL1
Mandell, AI1
Lynch, MG1
Brown, RH1
Nguyen, H1
Drake, MM3
Ofner, S1
Smith, TJ1
Long, DA1
Johns, GE1
Mullen, RS1
Bowe, RG1
Alexander, D1
Weiss, MJ1
Masi, RJ1
Charap, AD1
Eto, CY1
Weinreb, RN2
van Buskirk, EM2
Cherniack, R1
Stewart, RH1
Kimbrough, RL1
Ward, RL1
Roholt, PC1
Berry, DP1
Lustgarten, JS1
Podos, SM1
Harris, LS1
Greenstein, SH1
Bloom, AF1
Orlando, RG1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Safety and Efficacy Study of BETOPTIC S 0.25% and Timolol Gel-forming Solution 0.25% and 0.5% in Pediatric Patients With Glaucoma or Ocular Hypertension[NCT00061542]Phase 3105 participants (Actual)Interventional2003-01-31Completed
Evaluation of Macular Thickness in Patients With Glaucoma in Use of Topical Prostaglandin Analogue Undergoing Trabeculectomy With Mitomycin C[NCT06000280]37 participants (Actual)Interventional2021-01-04Completed
Safety and Efficacy Study of BETAXON 0.5% and AZOPT 1.0% in Pediatric Patients With Glaucoma or Ocular Hypertension[NCT00061516]Phase 378 participants (Actual)Interventional2003-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

15 reviews available for betaxolol and Glaucoma

ArticleYear
New approaches to antiglaucoma therapy.
    Journal of medicinal chemistry, 1997, Aug-29, Volume: 40, Issue:18

    Topics: Adenosine; Animals; Antihypertensive Agents; Cannabinoids; Drug Design; Endothelins; Glaucoma; Guany

1997
[Neuroprotection in glaucoma].
    Annales Academiae Medicae Stetinensis, 2007, Volume: 53 Suppl 1

    Topics: Betaxolol; Brimonidine Tartrate; Disease Progression; Glaucoma; Guanidines; Humans; Memantine; Neuro

2007
Is the medication used to achieve the target intraocular pressure in glaucoma therapy of relevance?--an exemplary analysis on the basis of two beta-blockers.
    Progress in retinal and eye research, 2010, Volume: 29, Issue:1

    Topics: Adrenergic beta-Antagonists; Betaxolol; Glaucoma; Humans; Intraocular Pressure; Timolol; Visual Fiel

2010
Factors for progression and glaucoma treatment: the Early Manifest Glaucoma Trial.
    Current opinion in ophthalmology, 2004, Volume: 15, Issue:2

    Topics: Antihypertensive Agents; Betaxolol; Combined Modality Therapy; Disease Progression; Glaucoma; Humans

2004
Effectiveness of levobetaxolol and timolol at blunting retinal ischaemia is related to their calcium and sodium blocking activities: relevance to glaucoma.
    Brain research bulletin, 2004, Feb-15, Volume: 62, Issue:6

    Topics: Animals; Betaxolol; Calcium; Glaucoma; Humans; Ischemia; Retina; Sodium; Sodium-Calcium Exchanger; T

2004
Are there any benefits of Betoptic S (betaxolol HCl ophthalmic suspension) over other beta-blockers in the treatment of glaucoma?
    Expert opinion on pharmacotherapy, 2004, Volume: 5, Issue:5

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Betaxolol; Glaucoma; Humans; Ophthalmic Soluti

2004
Treatment of glaucoma.
    Annual review of medicine, 1984, Volume: 35

    Topics: Betaxolol; Epinephrine; Glaucoma; Glaucoma, Open-Angle; Humans; Hydroxydopamines; Laser Therapy; Lev

1984
Acute pulmonary edema associated with ocular metipranolol use.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:4

    Topics: Aged; Betaxolol; Clinical Trials as Topic; Female; Glaucoma; Humans; Metipranolol; Ophthalmic Soluti

1995
Topical ophthalmic beta blockers: a comparative review.
    Journal of ocular pharmacology, 1993,Winter, Volume: 9, Issue:4

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Betaxolol; Carteolol; Drug Tolerance;

1993
Topical ophthalmic beta-adrenergic blockade for the treatment of glaucoma and ocular hypertension.
    Journal of clinical pharmacology, 1994, Volume: 34, Issue:8

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Betaxolol; Carteolol; Glaucoma; Humans; Levobu

1994
Brimonidine: a new alpha2-adrenoreceptor agonist for glaucoma treatment.
    Journal of glaucoma, 1997, Volume: 6, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Betaxolol; Brimonidine Tartrate; Clinical Tr

1997
Ocular betaxolol. A review of its pharmacological properties, and therapeutic efficacy in glaucoma and ocular hypertension.
    Drugs, 1990, Volume: 40, Issue:1

    Topics: Betaxolol; Eye Diseases; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions

1990
Pharmacologic effects of beta-blocking agents used in the management of glaucoma.
    Survey of ophthalmology, 1989, Volume: 33 Suppl

    Topics: Adrenergic beta-Antagonists; Betaxolol; Carteolol; Glaucoma; Heart Rate; Humans; Intraocular Pressur

1989
Betaxolol.
    Australian and New Zealand journal of ophthalmology, 1989, Volume: 17, Issue:1

    Topics: Adrenergic beta-Antagonists; Betaxolol; Glaucoma; Humans; Intraocular Pressure; Propanolamines; Time

1989
Comparison of ophthalmic beta-blocking agents.
    Clinical pharmacy, 1987, Volume: 6, Issue:6

    Topics: Adrenergic beta-Antagonists; Betaxolol; Cardiovascular System; Clinical Trials as Topic; Glaucoma; H

1987

Trials

32 trials available for betaxolol and Glaucoma

ArticleYear
The prophylactic effect of betaxolol 0.5% versus brimonidine 0.2% on IOP elevation after Nd:YAG laser posterior capsulotomy.
    Clinical & experimental optometry, 2022, Volume: 105, Issue:8

    Topics: Betaxolol; Brimonidine Tartrate; Capsule Opacification; Glaucoma; Humans; Intraocular Pressure; Lens

2022
Direct and crossover effects of brinzolamide, betaxolol, and latanoprost on choroidal thickness.
    Cutaneous and ocular toxicology, 2019, Volume: 38, Issue:2

    Topics: Adult; Antihypertensive Agents; Betaxolol; Choroid; Glaucoma; Humans; Latanoprost; Middle Aged; Sulf

2019
Betaxolol hydrochloride ophthalmic suspension 0.25% and timolol gel-forming solution 0.25% and 0.5% in pediatric glaucoma: a randomized clinical trial.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2009, Volume: 13, Issue:4

    Topics: Antihypertensive Agents; Betaxolol; Child; Child, Preschool; Double-Blind Method; Female; Gels; Glau

2009
The ability of short-wavelength automated perimetry to predict conversion to glaucoma.
    Ophthalmology, 2010, Volume: 117, Issue:1

    Topics: Aged; Antihypertensive Agents; Betaxolol; Double-Blind Method; Female; Follow-Up Studies; Glaucoma;

2010
Does glaucoma medication influence the diameter of the retinal arteriole in the human eye? (A pilot study using the retinal vessel analyser).
    Acta physiologica Hungarica, 2001, Volume: 88, Issue:3-4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Art

2001
Progression of retinal nerve fibre layer damage in betaxolol- and timolol-treated glaucoma patients.
    Acta ophthalmologica Scandinavica, 2002, Volume: 80, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Betaxolol; Disease Progression; Double-Blind Method; Femal

2002
Results of the betaxolol versus placebo treatment trial in ocular hypertension.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2003, Volume: 241, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Betaxolol; Double-Blind Method; Female; Glaucoma; Humans; Intraoc

2003
The effect of topical glaucoma medications evaluated by perimetry.
    The British journal of ophthalmology, 2003, Volume: 87, Issue:6

    Topics: Administration, Topical; Antihypertensive Agents; Betaxolol; Clonidine; Epinephrine; Glaucoma; Human

2003
Factors for progression and glaucoma treatment: the Early Manifest Glaucoma Trial.
    Current opinion in ophthalmology, 2004, Volume: 15, Issue:2

    Topics: Antihypertensive Agents; Betaxolol; Combined Modality Therapy; Disease Progression; Glaucoma; Humans

2004
[Early Manifest Glaucoma Trial update 2004].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2005, Volume: 102, Issue:3

    Topics: Aged; Antihypertensive Agents; Betaxolol; Combined Modality Therapy; Disease Progression; Female; Fo

2005
Efficacy of brinzolamide and levobetaxolol in pediatric glaucomas: a randomized clinical trial.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2008, Volume: 12, Issue:3

    Topics: Adrenergic beta-Antagonists; Betaxolol; Carbonic Anhydrase Inhibitors; Child; Child, Preschool; Dose

2008
Betaxolol and timolol.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1984, Volume: 102, Issue:10

    Topics: Adrenergic beta-Antagonists; Betaxolol; Clinical Trials as Topic; Glaucoma; Humans; Intraocular Pres

1984
Retrobulbar arterial hemodynamic effects of betaxolol and timolol in normal-tension glaucoma.
    American journal of ophthalmology, 1995, Volume: 120, Issue:2

    Topics: Arteries; Betaxolol; Blood Flow Velocity; Cross-Over Studies; Double-Blind Method; Female; Glaucoma;

1995
Unsuspected bronchospasm in association with topical timolol--a common problem in elderly people: can we easily identify those affected and do cardioselective agents lead to improvement?
    Age and ageing, 1994, Volume: 23, Issue:1

    Topics: Aged; Aged, 80 and over; Airway Resistance; Betaxolol; Bronchial Spasm; Female; Forced Expiratory Vo

1994
Improved lung function tests on changing from topical timolol: non-selective beta-blockade impairs lung function tests in elderly patients.
    Eye (London, England), 1993, Volume: 7 ( Pt 5)

    Topics: Administration, Topical; Aged; Aged, 80 and over; Betaxolol; Female; Forced Expiratory Volume; Glauc

1993
A clinical trial of MK-507, Trusopt, for raised intraocular pressure--the Australian experience.
    Australian and New Zealand journal of ophthalmology, 1996, Volume: 24, Issue:2

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Australia; Bet

1996
Randomised, controlled trial of spirometric changes in elderly people receiving timolol or betaxolol as initial treatment for glaucoma.
    The British journal of ophthalmology, 1998, Volume: 82, Issue:2

    Topics: Aged; Antihypertensive Agents; Betaxolol; Double-Blind Method; Female; Glaucoma; Humans; Intraocular

1998
Effects of glaucoma medications on the cardiorespiratory and intraocular pressure status of newly diagnosed glaucoma patients.
    The British journal of ophthalmology, 2000, Volume: 84, Issue:7

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Analysis of Variance; Betaxolol; Blood

2000
[Betoptic, a new possibility in the treatment of glaucoma].
    Ceskoslovenska oftalmologie, 1992, Volume: 48, Issue:4

    Topics: Aged; Aged, 80 and over; Betaxolol; Blood Pressure; Glaucoma; Humans; Intraocular Pressure; Timolol

1992
Changes in depressive status associated with topical beta-blockers.
    International ophthalmology, 1992, Volume: 16, Issue:4-5

    Topics: Adult; Aged; Betaxolol; Brain; Depression; Double-Blind Method; Female; Glaucoma; Humans; Male; Midd

1992
Influence of betaxolol and timolol on the visual fields of patients with glaucoma.
    American journal of ophthalmology, 1991, Dec-15, Volume: 112, Issue:6

    Topics: Aged; Betaxolol; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle A

1991
Cardiovascular effects of befunolol, betaxolol and timolol eye drops.
    International journal of clinical pharmacology research, 1990, Volume: 10, Issue:3

    Topics: Adrenergic beta-Antagonists; Betaxolol; Blood Pressure; Double-Blind Method; Electrocardiography; Fe

1990
The effect of topical antiglaucoma drugs on the results of high-pass resolution perimetry.
    American journal of ophthalmology, 1991, Jun-15, Volume: 111, Issue:6

    Topics: Administration, Topical; Aged; Betaxolol; Double-Blind Method; Epinephrine; Female; Glaucoma; Humans

1991
Changing therapy from timolol to betaxolol. Effect on intraocular pressure in selected patients with glaucoma. Timolol-Betaxolol Study Group.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1989, Volume: 107, Issue:9

    Topics: Adrenergic beta-Antagonists; Betaxolol; Blood Pressure; Glaucoma; Humans; Intraocular Pressure; Prop

1989
[Use of Betaxolol in patients with glaucoma and chronic nonspecific diseases of the respiratory system].
    Klinika oczna, 1989, Volume: 91, Issue:6

    Topics: Aged; Betaxolol; Clinical Trials as Topic; Female; Glaucoma; Humans; Intraocular Pressure; Lung Dise

1989
Betaxolol eye drops as a safe medication to lower intraocular pressure.
    Australian and New Zealand journal of ophthalmology, 1987, Volume: 15, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Betaxolol; Clinical Trials as Topic; Cornea; F

1987
Comparison of ophthalmic beta-blocking agents.
    Clinical pharmacy, 1987, Volume: 6, Issue:6

    Topics: Adrenergic beta-Antagonists; Betaxolol; Cardiovascular System; Clinical Trials as Topic; Glaucoma; H

1987
A comparison of betaxolol and timolol in open angle glaucoma and ocular hypertension.
    Acta ophthalmologica, 1988, Volume: 66, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Betaxolol; Clinical Trials as Topic; Double-Blind Method; Female

1988
Topical beta-blocker therapy and central nervous system side effects. A preliminary study comparing betaxolol and timolol.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1988, Volume: 106, Issue:7

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Betaxolol; Central Nervous System

1988
Levobunolol and betaxolol. A double-masked controlled comparison of efficacy and safety in patients with elevated intraocular pressure.
    Ophthalmology, 1988, Volume: 95, Issue:6

    Topics: Betaxolol; Clinical Trials as Topic; Double-Blind Method; Glaucoma; Humans; Intraocular Pressure; Le

1988
[Effect of nonspecific and cardioselective beta receptor blockers on the formation of aqueous humor. An oculopressure tonometry study].
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1988, Volume: 196, Issue:2

    Topics: Adult; Betaxolol; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma; Humans; Intraocul

1988
Betaxolol vs timolol. A six-month double-blind comparison.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1986, Volume: 104, Issue:1

    Topics: Adult; Aged; Betaxolol; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma; Humans; Int

1986

Other Studies

56 other studies available for betaxolol and Glaucoma

ArticleYear
Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H
    International journal of molecular sciences, 2022, Nov-09, Volume: 23, Issue:22

    Topics: Antiglaucoma Agents; Betaxolol; Gasotransmitters; Glaucoma; Humans; Hydrogen Sulfide

2022
Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H
    International journal of molecular sciences, 2022, Nov-09, Volume: 23, Issue:22

    Topics: Antiglaucoma Agents; Betaxolol; Gasotransmitters; Glaucoma; Humans; Hydrogen Sulfide

2022
Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H
    International journal of molecular sciences, 2022, Nov-09, Volume: 23, Issue:22

    Topics: Antiglaucoma Agents; Betaxolol; Gasotransmitters; Glaucoma; Humans; Hydrogen Sulfide

2022
Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H
    International journal of molecular sciences, 2022, Nov-09, Volume: 23, Issue:22

    Topics: Antiglaucoma Agents; Betaxolol; Gasotransmitters; Glaucoma; Humans; Hydrogen Sulfide

2022
Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H
    International journal of molecular sciences, 2022, Nov-09, Volume: 23, Issue:22

    Topics: Antiglaucoma Agents; Betaxolol; Gasotransmitters; Glaucoma; Humans; Hydrogen Sulfide

2022
Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H
    International journal of molecular sciences, 2022, Nov-09, Volume: 23, Issue:22

    Topics: Antiglaucoma Agents; Betaxolol; Gasotransmitters; Glaucoma; Humans; Hydrogen Sulfide

2022
Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H
    International journal of molecular sciences, 2022, Nov-09, Volume: 23, Issue:22

    Topics: Antiglaucoma Agents; Betaxolol; Gasotransmitters; Glaucoma; Humans; Hydrogen Sulfide

2022
Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H
    International journal of molecular sciences, 2022, Nov-09, Volume: 23, Issue:22

    Topics: Antiglaucoma Agents; Betaxolol; Gasotransmitters; Glaucoma; Humans; Hydrogen Sulfide

2022
Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H
    International journal of molecular sciences, 2022, Nov-09, Volume: 23, Issue:22

    Topics: Antiglaucoma Agents; Betaxolol; Gasotransmitters; Glaucoma; Humans; Hydrogen Sulfide

2022
Critical Evaluation of Multifunctional Betaxolol Hydrochloride Nanoformulations for Effective Sustained Intraocular Pressure Reduction.
    International journal of nanomedicine, 2022, Volume: 17

    Topics: Betaxolol; Cornea; Drug Carriers; Glaucoma; Humans; Intraocular Pressure; Nanoparticles; Particle Si

2022
Critical Evaluation of Multifunctional Betaxolol Hydrochloride Nanoformulations for Effective Sustained Intraocular Pressure Reduction.
    International journal of nanomedicine, 2022, Volume: 17

    Topics: Betaxolol; Cornea; Drug Carriers; Glaucoma; Humans; Intraocular Pressure; Nanoparticles; Particle Si

2022
Critical Evaluation of Multifunctional Betaxolol Hydrochloride Nanoformulations for Effective Sustained Intraocular Pressure Reduction.
    International journal of nanomedicine, 2022, Volume: 17

    Topics: Betaxolol; Cornea; Drug Carriers; Glaucoma; Humans; Intraocular Pressure; Nanoparticles; Particle Si

2022
Critical Evaluation of Multifunctional Betaxolol Hydrochloride Nanoformulations for Effective Sustained Intraocular Pressure Reduction.
    International journal of nanomedicine, 2022, Volume: 17

    Topics: Betaxolol; Cornea; Drug Carriers; Glaucoma; Humans; Intraocular Pressure; Nanoparticles; Particle Si

2022
Betaxolol, Brimonidin and Carteolol in the Therapy of Normal-Tension Glaucoma.
    Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti, 2020,Spring, Volume: 76, Issue:2

    Topics: Betaxolol; Carteolol; Evoked Potentials, Visual; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular

2020
Betaxolol-loaded niosomes integrated within pH-sensitive in situ forming gel for management of glaucoma.
    International journal of pharmaceutics, 2021, Apr-01, Volume: 598

    Topics: Animals; Betaxolol; Drug Carriers; Drug Delivery Systems; Gels; Glaucoma; Hydrogen-Ion Concentration

2021
Controlled drug delivery for glaucoma therapy using montmorillonite/Eudragit microspheres as an ion-exchange carrier.
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Animals; Bentonite; Betaxolol; Biological Availability; Cell Death; Chorioallantoic Membrane; Delaye

2018
Montmorillonite/chitosan nanoparticles as a novel controlled-release topical ophthalmic delivery system for the treatment of glaucoma.
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Administration, Topical; Animals; Aqueous Humor; Bentonite; Betaxolol; Cell Survival; Chitosan; Corn

2018
Betaxolol hydrochloride loaded chitosan nanoparticles for ocular delivery and their anti-glaucoma efficacy.
    Current drug delivery, 2013, Volume: 10, Issue:5

    Topics: Administration, Ophthalmic; Animals; Antihypertensive Agents; Betaxolol; Chickens; Chitosan; Chorioa

2013
[Current trend of glaucoma medication with various eye drops].
    Nippon Ganka Gakkai zasshi, 2013, Volume: 117, Issue:10

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Betaxolo

2013
Persistence of glaucoma medical therapy in the Glasgow Glaucoma Database.
    The British journal of ophthalmology, 2011, Volume: 95, Issue:7

    Topics: Algorithms; Antihypertensive Agents; Betaxolol; Brimonidine Tartrate; Clinical Protocols; Databases,

2011
Delaying glaucoma.
    Health news (Waltham, Mass.), 2002, Volume: 8, Issue:12

    Topics: Antihypertensive Agents; Betaxolol; Disease Progression; Glaucoma; Humans; Intraocular Pressure; Las

2002
Effects of commercial antiglaucoma drugs to glutamate-induced [Ca2+)]i increase in cultured neuroblastoma cells.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2003, Volume: 19, Issue:3

    Topics: Animals; Antihypertensive Agents; Betaxolol; Brimonidine Tartrate; Calcium; Carteolol; Cell Death; D

2003
In vitro effects of preserved or preservative-free antiglaucoma medications on human complement system.
    Current eye research, 2003, Volume: 27, Issue:4

    Topics: Adrenergic beta-Antagonists; Benzalkonium Compounds; Betaxolol; Carteolol; Complement System Protein

2003
Prescription of topical antiglaucoma agents for patients with contraindications to beta-blockers.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2003, Volume: 38, Issue:6

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Betaxolo

2003
[Neuroprotection and vasoprotection in glaucoma].
    Oftalmologia (Bucharest, Romania : 1990), 2004, Volume: 48, Issue:2

    Topics: Antihypertensive Agents; Betaxolol; Brimonidine Tartrate; Carteolol; Drug Therapy, Combination; Glau

2004
Infantile glaucoma in a patient with Rothmund-Thomson syndrome.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2004, Volume: 39, Issue:6

    Topics: Adolescent; Antihypertensive Agents; Betaxolol; Female; Glaucoma; Humans; Intraocular Pressure; Roth

2004
[Increased intraocular pressure in asthma patients].
    Medizinische Monatsschrift fur Pharmazeuten, 2005, Volume: 28, Issue:8

    Topics: Adrenergic beta-Agonists; Anti-Asthmatic Agents; Asthma; Betaxolol; Glaucoma; Glucocorticoids; Human

2005
Concentrations of betaxolol in ocular tissues of patients with glaucoma and normal monkeys after 1 month of topical ocular administration.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:1

    Topics: Administration, Topical; Adult; Aged; Animals; Antihypertensive Agents; Betaxolol; Biological Availa

2006
Effects of antiglaucoma drugs on calcium mobility in cultured corneal endothelial cells.
    The Kaohsiung journal of medical sciences, 2006, Volume: 22, Issue:2

    Topics: Animals; Antihypertensive Agents; Betaxolol; Calcium; Endothelium, Corneal; Glaucoma; Levobunolol; M

2006
[Clinical investigation: the intraocular pressure-lowering efficacy and safety of brinzolamide combined with betaxolol].
    Yan ke xue bao = Eye science, 2005, Volume: 21, Issue:4

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Betaxolol; Carbonic Anhydrase Inhibitors; Female;

2005
Cellular cytotoxicity of antiglaucoma drugs in cultured corneal endothelial cells.
    The Kaohsiung journal of medical sciences, 2007, Volume: 23, Issue:3

    Topics: Animals; Betaxolol; Carteolol; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Endothelia

2007
A cardiovascular benefit of ophthalmic beta-blockade.
    Age and ageing, 2007, Volume: 36, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged, 80 and over; Atrial Fibrillation; Betaxolol; Biological Availabil

2007
Pharmacological neuroprotection for glaucoma.
    Drugs, 2007, Volume: 67, Issue:15

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Betaxolol; Eye; Glaucoma; Humans; Neuroprotect

2007
Direct inhibition of N-methyl-D-aspartate (NMDA)-receptor function by antiglaucomatous beta-antagonists.
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Betaxolol; Calcium; Dose-Response Relationship, Drug; Excitato

2008
The effect of treatment on the results of high-pass resolution perimetry in glaucoma.
    Acta ophthalmologica, 1994, Volume: 72, Issue:4

    Topics: Aged; Betaxolol; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Male; Ocula

1994
Contact allergy to beta-blocking agents in ophthalmic preparations.
    Contact dermatitis, 1993, Volume: 28, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Betaxolol; Dermatitis, Allergic Contact; Drug Eruptions; Glaucoma

1993
Intraocular pressure reduction with topically administered pilocarpine, timolol and betaxolol in normal tension glaucoma.
    Acta ophthalmologica, 1993, Volume: 71, Issue:5

    Topics: Administration, Topical; Aged; Aged, 80 and over; Analysis of Variance; Betaxolol; Female; Glaucoma;

1993
The safety of topical beta-blockers in glaucoma treatment.
    The Medical journal of Australia, 1996, Apr-15, Volume: 164, Issue:8

    Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Betaxolol; Glaucoma; Humans; Levobunolol; Ophthalmic

1996
The safety of topical beta-blockers in glaucoma treatment.
    The Medical journal of Australia, 1996, Aug-05, Volume: 165, Issue:3

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Betaxolol; Glaucoma; Humans

1996
Effects of pilocarpine and other antiglaucoma drugs on cultured human Tenon's fibroblast cells.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1997, Volume: 13, Issue:1

    Topics: Adrenergic beta-Antagonists; Betaxolol; Carteolol; Cell Division; Cells, Cultured; Eye; Fibroblasts;

1997
Ocular-specific chemical delivery systems of betaxolol for safe local treatment of glaucoma.
    Drug design and discovery, 1997, Volume: 15, Issue:2

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Betaxolol; Eye; Glaucoma; Intraocular

1997
Five-year follow-up of treated patients with glaucoma using resolution perimetry.
    Journal of glaucoma, 1998, Volume: 7, Issue:1

    Topics: Aged; Betaxolol; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular

1998
Glaucoma drops control intraocular pressure and protect optic nerves in a rat model of glaucoma.
    Investigative ophthalmology & visual science, 1998, Volume: 39, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Betaxolol; Clonidine; Disease Model

1998
[A long-term study of the visual fields in patients treated with betaxolol and timolol].
    Oftalmologia (Bucharest, Romania : 1990), 1998, Volume: 42, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Belgium; Betaxolol; Female; Glaucoma; Glaucoma, Angle-Clos

1998
Severe nausea and vomiting with timolol eye drops.
    Lancet (London, England), 1998, Aug-01, Volume: 352, Issue:9125

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Betaxolol; Female; Glaucoma; Humans; Ind

1998
Periocular accumulation of timolol and betaxolol in glaucoma patients under long-term therapy.
    Survey of ophthalmology, 1999, Volume: 43 Suppl 1

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Betaxolol; Biological Availability; Chr

1999
Plasma concentration of topically applied betaxolol in elderly glaucoma patients.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2001, Volume: 17, Issue:3

    Topics: Absorption; Administration, Topical; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Antihyper

2001
Comparative effects of antiglaucoma drugs on voltage-dependent calcium channels.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2001, Volume: 239, Issue:7

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Betaxolol; Calcium; Calcium Channels;

2001
Antiglaucoma medication and clinical depression.
    The Australian and New Zealand journal of psychiatry, 2001, Volume: 35, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Betaxolol; Depressive Disorder, Major; Glaucoma; Humans; Male; Op

2001
[Prospects for neuroprotective glaucoma therapy].
    Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2001, Volume: 98, Issue:10

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Apoptosis;

2001
Reactivation of herpes simplex virus keratitis after initiating bimatoprost treatment for glaucoma.
    American journal of ophthalmology, 2002, Volume: 133, Issue:3

    Topics: Acyclovir; Aged; Amides; Anti-Infective Agents; Anti-Inflammatory Agents; Antihypertensive Agents; A

2002
[Nanocapsules of beta-blocking agents: a new drug carrier in ophthalmology. Application to medical treatment of glaucoma in rabbits].
    Journal francais d'ophtalmologie, 1991, Volume: 14, Issue:6-7

    Topics: Adrenergic beta-Antagonists; Animals; Betaxolol; Capsules; Colloids; Dosage Forms; Dose-Response Rel

1991
Cardiovascular and pulmonary effects of beta-blocking agents: implications for their use in ophthalmology.
    Survey of ophthalmology, 1989, Volume: 33 Suppl

    Topics: Adrenergic beta-Antagonists; Age Factors; Betaxolol; Cardiovascular System; Drug Interactions; Glauc

1989
Pressure compliance test of the optic nerve head: influence of different antiglaucoma drugs.
    Survey of ophthalmology, 1989, Volume: 33 Suppl

    Topics: Acetazolamide; Adrenergic beta-Antagonists; Betaxolol; Carteolol; Glaucoma; Glaucoma, Open-Angle; Hu

1989
Drugs and glaucoma.
    American family physician, 1986, Volume: 34, Issue:1

    Topics: Adrenergic beta-Antagonists; Betaxolol; Carbonic Anhydrase Inhibitors; Drug Combinations; Drug Impla

1986
Glaucoma.
    American family physician, 1987, Volume: 35, Issue:1

    Topics: Adrenergic beta-Antagonists; Betaxolol; Glaucoma; Glaucoma, Open-Angle; Humans; Infant, Newborn; Las

1987
Early postmarketing surveillance of betaxolol hydrochloride, September 1985-September 1986.
    American journal of ophthalmology, 1987, Apr-15, Volume: 103, Issue:4

    Topics: Adrenergic beta-Antagonists; Betaxolol; Glaucoma; Humans; Ocular Hypertension; Product Surveillance,

1987
Betaxolol in patients with glaucoma and asthma.
    American journal of ophthalmology, 1987, Apr-15, Volume: 103, Issue:4

    Topics: Adrenergic beta-Antagonists; Asthma; Betaxolol; Glaucoma; Humans; Propanolamines

1987
New topical beta-blockers for glaucoma.
    Drug and therapeutics bulletin, 1987, Aug-10, Volume: 25, Issue:16

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Betaxolol; Carteolol; Glaucoma; Humans; Metipr

1987
Betaxolol and levobunolol: new beta-blocking antiglaucoma agents.
    Journal of the American Optometric Association, 1987, Volume: 58, Issue:9

    Topics: Adrenergic beta-Antagonists; Betaxolol; Chemical Phenomena; Chemistry; Glaucoma; Humans; Intraocular

1987
[Betaxolol. A new beta blockader with beta-1-selectivity in glaucoma treatment].
    Ugeskrift for laeger, 1988, Mar-21, Volume: 150, Issue:12

    Topics: Adrenergic beta-Antagonists; Betaxolol; Glaucoma; Humans; Propanolamines

1988
Betaxolol in chronic obstructive pulmonary disease.
    Journal of ocular pharmacology, 1987,Summer, Volume: 3, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Betaxolol; Forced Expiratory Volume; Glaucoma; Humans; Intraocula

1987
Long-term betaxolol therapy in glaucoma patients with pulmonary disease.
    American journal of ophthalmology, 1988, Aug-15, Volume: 106, Issue:2

    Topics: Aged; Asthma; Betaxolol; Female; Glaucoma; Humans; Intraocular Pressure; Lung Diseases; Male; Middle

1988
Betaxolol and restrictive airway disease. Case report.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1987, Volume: 105, Issue:9

    Topics: Aged; Betaxolol; Female; Glaucoma; Humans; Propanolamines; Respiration Disorders

1987
Betaxolol in patients with glaucoma and asthma.
    American journal of ophthalmology, 1986, May-15, Volume: 101, Issue:5

    Topics: Administration, Topical; Adult; Aged; Asthma; Betaxolol; Female; Glaucoma; Humans; Lung Volume Measu

1986
Respiratory difficulties with betaxolol.
    American journal of ophthalmology, 1986, Aug-15, Volume: 102, Issue:2

    Topics: Aged; Airway Obstruction; Asthma; Betaxolol; Female; Glaucoma; Humans; Male; Middle Aged; Ophthalmic

1986
Clinical depression associated with betaxolol.
    American journal of ophthalmology, 1986, Aug-15, Volume: 102, Issue:2

    Topics: Betaxolol; Depression; Female; Glaucoma; Humans; Middle Aged; Propanolamines

1986