Page last updated: 2024-10-16

betaine and Weight Gain

betaine has been researched along with Weight Gain in 32 studies

glycine betaine : The amino acid betaine derived from glycine.

Weight Gain: Increase in BODY WEIGHT over existing weight.

Research Excerpts

ExcerptRelevanceReference
"Betaine is a nontoxic, chemically stable and naturally occurring molecule."5.48Betaine Supplementation Enhances Lipid Metabolism and Improves Insulin Resistance in Mice Fed a High-Fat Diet. ( Bai, L; Du, J; Gan, M; Jiang, A; Jiang, Y; Jin, L; Li, M; Li, X; Ma, J; Shen, L; Tan, Z; Tang, G; Wang, J; Xu, Y; Yang, Q; Zhang, P; Zhang, S; Zhao, X; Zhu, L, 2018)
"Ecological evidence suggests that niacin (nicotinamide and nicotinic acid) fortification may be involved in the increased prevalence of obesity and type 2 diabetes, both of which are associated with insulin resistance and epigenetic changes."3.79Nicotinamide supplementation induces detrimental metabolic and epigenetic changes in developing rats. ( Cao, JM; Cao, Y; Gong, XJ; Guo, J; Guo, M; Li, D; Lun, YZ; Luo, N; Sun, WP; Tian, YJ; Zhou, SS, 2013)
"Betaine (BET) reduces diet-induced liver lipid accumulation, and may relieve obesity-related metabolic disturbances."3.79Betaine supplementation causes increase in carnitine metabolites in the muscle and liver of mice fed a high-fat diet as studied by nontargeted LC-MS metabolomics approach. ( Auriola, S; Hanhineva, K; Huotari, A; Keski-Rahkonen, P; Kolehmainen, M; Lehtonen, M; Mykkänen, H; Olli, K; Pekkinen, J; Poutanen, K; Tiihonen, K, 2013)
" There was no benefit from the substitution of betaine for choline as measured by egg production, egg weight, egg content, or weight gain."3.71Betaine does not improve performance of laying hens when the diet contains adequate choline. ( Harms, RH; Russell, GB, 2002)
"Betaine is a well-known component of poultry diets with various effects on nutritional physiology."3.11Comparing effects of natural betaine and betaine hydrochloride on gut physiology in broiler chickens. ( Awad, WA; Dublecz, K; Gavrău, A; Hess, M; Ruhnau, D, 2022)
"Betaine is a nontoxic, chemically stable and naturally occurring molecule."1.48Betaine Supplementation Enhances Lipid Metabolism and Improves Insulin Resistance in Mice Fed a High-Fat Diet. ( Bai, L; Du, J; Gan, M; Jiang, A; Jiang, Y; Jin, L; Li, M; Li, X; Ma, J; Shen, L; Tan, Z; Tang, G; Wang, J; Xu, Y; Yang, Q; Zhang, P; Zhang, S; Zhao, X; Zhu, L, 2018)
"Betaine-treated Tg-I278T Cbs (-/-) mice also exhibited increased levels of betaine-dependent homocysteine methyl transferase (BHMT), increased levels of the lipogenic enzyme stearoyl-coenzyme A desaturase (SCD-1), and increased lipid droplet accumulation in the liver."1.43Betaine supplementation is less effective than methionine restriction in correcting phenotypes of CBS deficient mice. ( Gupta, S; Kruger, WD; Wang, L, 2016)
"Nonalcoholic fatty liver disease (NAFLD) is now the most common cause of chronic liver disease among children and adolescents in the developed world."1.42FTO-dependent function of N6-methyladenosine is involved in the hepatoprotective effects of betaine on adolescent mice. ( Chen, J; Wang, X; Wang, Y; Wu, W; Zhou, X, 2015)
" A substantial portion of choline in SBM, CM and PM is unavailable, and overheating does not appear to decrease the bioavailability of choline in these products."1.30A chick bioassay approach for determining the bioavailable choline concentration in normal and overheated soybean meal, canola meal and peanut meal. ( Baker, DH; Emmert, JL, 1997)
"Experimental vitamin C deficiency in guinea pigs is associated with low carnitine concentrations in blood and some tissues."1.29The ability of guinea pigs to synthesize carnitine at a normal rate from epsilon-N-trimethyllysine or gamma-butyrobetaine in vivo is not compromised by experimental vitamin C deficiency. ( Rebouche, CJ, 1995)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (18.75)18.2507
2000's10 (31.25)29.6817
2010's12 (37.50)24.3611
2020's4 (12.50)2.80

Authors

AuthorsStudies
Sharma, NK1
Cadogan, DJ1
Chrystal, PV1
McGilchrist, P1
Wilkinson, SJ1
Inhuber, V1
Moss, AF1
Awad, WA1
Ruhnau, D1
Gavrău, A1
Dublecz, K1
Hess, M1
Dong, L1
Zhong, ZX1
Cui, HH1
Wang, SN1
Luo, Y1
Yu, LH1
Loor, JJ1
Wang, HR1
Lakhani, P1
Kumar, P1
Alhussien, MN1
Lakhani, N1
Grewal, S1
Vats, A1
Liu, F1
Cottrell, JJ1
Collins, CL1
Henman, DJ1
O'Halloran, KSB1
Dunshea, FR1
Du, J1
Shen, L1
Tan, Z1
Zhang, P1
Zhao, X1
Xu, Y1
Gan, M1
Yang, Q1
Ma, J1
Jiang, A1
Tang, G1
Jiang, Y1
Jin, L1
Li, M1
Bai, L1
Li, X2
Wang, J1
Zhang, S1
Zhu, L1
Li, D1
Tian, YJ1
Guo, J1
Sun, WP1
Lun, YZ1
Guo, M1
Luo, N1
Cao, Y1
Cao, JM1
Gong, XJ1
Zhou, SS1
Zhang, W1
Wang, LW1
Wang, LK1
Zhang, H1
Luo, LP1
Song, JC1
Gong, ZJ1
Pekkinen, J1
Olli, K1
Huotari, A1
Tiihonen, K1
Keski-Rahkonen, P1
Lehtonen, M1
Auriola, S1
Kolehmainen, M1
Mykkänen, H1
Poutanen, K1
Hanhineva, K1
Amerah, AM1
Ravindran, V1
He, S1
Zhao, S1
Dai, S1
Liu, D1
Bokhari, SG1
Chen, J1
Zhou, X1
Wu, W1
Wang, X1
Wang, Y1
Gupta, S1
Wang, L1
Kruger, WD1
Rojas-Cano, ML1
Lachica, M2
Lara, L1
Haro, A1
Fernández-Fígares, I2
Yang, Z1
Wang, ZY1
Yang, HM1
Zhao, FZ1
Kong, LL1
Jacobs, RL1
Zhao, Y1
Koonen, DP1
Sletten, T1
Su, B1
Lingrell, S1
Cao, G1
Peake, DA1
Kuo, MS1
Proctor, SD1
Kennedy, BP1
Dyck, JR1
Vance, DE1
Chamruspollert, M1
Pesti, GM2
Bakalli, RI2
Fetterer, RH1
Augustine, PC1
Allen, PC1
Barfield, RC1
Zhan, XA1
Li, JX1
Xu, ZR2
Zhao, RQ1
Huang, QC1
Han, XY1
Li, WF1
Dilger, RN1
Garrow, TA2
Baker, DH3
Conde-Aguilera, JA1
Nieto, R1
Aguilera, JF1
Rebouche, CJ1
Schutte, JB1
De Jong, J1
Smink, W1
Pack, M1
Emmert, JL2
Matthews, JO3
Ward, TL1
Southern, LL3
Webel, DM1
Biehl, RR1
Griffiths, MA1
Garrow, LS1
Pontif, JE1
Higbie, AD1
Bidner, TD1
Garcia Neto, M1
McDevitt, RM1
Mack, S1
Wallis, IR1
Harms, RH1
Russell, GB1

Trials

5 trials available for betaine and Weight Gain

ArticleYear
Comparing effects of natural betaine and betaine hydrochloride on gut physiology in broiler chickens.
    Poultry science, 2022, Volume: 101, Issue:12

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Betaine; Body Weight; Chickens; Di

2022
Effect of betaine supplementation on growth performance, nutrient intake and expression of IGF-1 in Karan Fries heifers during thermal stress.
    Theriogenology, 2020, Jan-15, Volume: 142

    Topics: Animal Nutritional Physiological Phenomena; Animals; Betaine; Cattle; Dietary Supplements; Energy In

2020
Effects of methionine and betaine supplementation on growth performance, carcase composition and metabolism of lipids in male broilers.
    British poultry science, 2006, Volume: 47, Issue:5

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Betaine; Body Composition; Carniti

2006
Betaine can partially spare choline in chicks but only when added to diets containing a minimal level of choline.
    The Journal of nutrition, 2007, Volume: 137, Issue:10

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Betaine; Chickens; Choline; Diet;

2007
Synergistic effects of betaine and conjugated linoleic acid on the growth and carcass composition of growing Iberian pigs.
    Journal of animal science, 2008, Volume: 86, Issue:1

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Betaine; Body Composition; Diet; D

2008

Other Studies

27 other studies available for betaine and Weight Gain

ArticleYear
Guanidinoacetic acid as a partial replacement to arginine with or without betaine in broilers offered moderately low crude protein diets.
    Poultry science, 2022, Volume: 101, Issue:4

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Betaine; Chickens; Creat

2022
Effects of rumen-protected betaine supplementation on meat quality and the composition of fatty and amino acids in growing lambs.
    Animal : an international journal of animal bioscience, 2020, Volume: 14, Issue:2

    Topics: Amino Acids; Animal Feed; Animals; Betaine; Body Weight; Diet; Dietary Supplements; Fatty Acids; Fat

2020
Supplementation of selenium, vitamin E, chromium and betaine above recommended levels improves lactating performance of sows over summer.
    Tropical animal health and production, 2017, Volume: 49, Issue:7

    Topics: Animal Feed; Animals; Betaine; Body Composition; Chromium; Diet; Dietary Supplements; Feeding Behavi

2017
Betaine Supplementation Enhances Lipid Metabolism and Improves Insulin Resistance in Mice Fed a High-Fat Diet.
    Nutrients, 2018, Jan-26, Volume: 10, Issue:2

    Topics: 3T3-L1 Cells; Adipocytes, White; Adipogenesis; Adiposity; Animals; Animals, Outbred Strains; Anti-Ob

2018
Nicotinamide supplementation induces detrimental metabolic and epigenetic changes in developing rats.
    The British journal of nutrition, 2013, Volume: 110, Issue:12

    Topics: Animals; Betaine; Choline; CpG Islands; Dietary Supplements; DNA; DNA Damage; DNA Methylation; Epige

2013
Betaine protects against high-fat-diet-induced liver injury by inhibition of high-mobility group box 1 and Toll-like receptor 4 expression in rats.
    Digestive diseases and sciences, 2013, Volume: 58, Issue:11

    Topics: Animals; Betaine; Chemical and Drug Induced Liver Injury; Cytokines; Dietary Fats; Fatty Liver; Fema

2013
Betaine supplementation causes increase in carnitine metabolites in the muscle and liver of mice fed a high-fat diet as studied by nontargeted LC-MS metabolomics approach.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:11

    Topics: Acetylcarnitine; Adipose Tissue; Adiposity; Animals; Betaine; Blood Glucose; Carnitine; Chromatograp

2013
Effect of coccidia challenge and natural betaine supplementation on performance, nutrient utilization, and intestinal lesion scores of broiler chickens fed suboptimal level of dietary methionine.
    Poultry science, 2015, Volume: 94, Issue:4

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Betaine; Chickens; Coccidiosis; Di

2015
Effects of dietary betaine on growth performance, fat deposition and serum lipids in broilers subjected to chronic heat stress.
    Animal science journal = Nihon chikusan Gakkaiho, 2015, Volume: 86, Issue:10

    Topics: Adipose Tissue; Animal Feed; Animals; Betaine; Body Composition; Body Fat Distribution; Chickens; Di

2015
FTO-dependent function of N6-methyladenosine is involved in the hepatoprotective effects of betaine on adolescent mice.
    Journal of physiology and biochemistry, 2015, Volume: 71, Issue:3

    Topics: Adenosine; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Animals; Betaine; Blood Glucose; Cholester

2015
Betaine supplementation is less effective than methionine restriction in correcting phenotypes of CBS deficient mice.
    Journal of inherited metabolic disease, 2016, Volume: 39, Issue:1

    Topics: Animals; Betaine; Bone Density; Cystathionine beta-Synthase; Diet; Dietary Supplements; Disease Mode

2016
Portal-drained viscera heat production in Iberian pigs fed betaine- and conjugated linoleic acid-supplemented diets.
    Journal of the science of food and agriculture, 2017, Volume: 97, Issue:2

    Topics: Animals; Animals, Inbred Strains; Betaine; Body Composition; Body Temperature Regulation; Diet; Ener

2017
Response of growing goslings to dietary supplementation with methionine and betaine.
    British poultry science, 2016, Volume: 57, Issue:6

    Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Betaine; Diet; Dietar

2016
Impaired de novo choline synthesis explains why phosphatidylethanolamine N-methyltransferase-deficient mice are protected from diet-induced obesity.
    The Journal of biological chemistry, 2010, Jul-16, Volume: 285, Issue:29

    Topics: Animals; Betaine; Choline; Diet; Dietary Fats; Dietary Supplements; Energy Metabolism; Fatty Liver;

2010
The influence of labile dietary methyl donors on the arginine requirement of young broiler chicks.
    Poultry science, 2002, Volume: 81, Issue:8

    Topics: Animal Nutritional Physiological Phenomena; Animals; Arginine; Betaine; Chickens; Creatine; Diet; Ea

2002
The effect of dietary betaine on intestinal and plasma levels of betaine in uninfected and coccidia-infected broiler chicks.
    Parasitology research, 2003, Volume: 90, Issue:4

    Topics: Animals; Betaine; Chickens; Coccidiosis; Diet; Duodenum; Eimeria; Eimeria tenella; Intestinal Absorp

2003
Effect of betaine on growth hormone pulsatile secretion and serum metabolites in finishing pigs.
    Journal of animal physiology and animal nutrition, 2007, Volume: 91, Issue:3-4

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Betaine; Blood Urea Nitrogen; Dose

2007
The ability of guinea pigs to synthesize carnitine at a normal rate from epsilon-N-trimethyllysine or gamma-butyrobetaine in vivo is not compromised by experimental vitamin C deficiency.
    Metabolism: clinical and experimental, 1995, Volume: 44, Issue:5

    Topics: Analysis of Variance; Animals; Ascorbic Acid Deficiency; Betaine; Carnitine; Food, Fortified; Guinea

1995
Replacement value of betaine for DL-methionine in male broiler chicks.
    Poultry science, 1997, Volume: 76, Issue:2

    Topics: Analysis of Variance; Animal Feed; Animals; Betaine; Body Composition; Chickens; Food, Fortified; Ma

1997
A chick bioassay approach for determining the bioavailable choline concentration in normal and overheated soybean meal, canola meal and peanut meal.
    The Journal of nutrition, 1997, Volume: 127, Issue:5

    Topics: Animal Feed; Animals; Arachis; Betaine; Biological Assay; Biological Availability; Body Weight; Bras

1997
Interactive effects of betaine and monensin in uninfected and Eimeria acervulina-infected chicks.
    Poultry science, 1997, Volume: 76, Issue:7

    Topics: Animal Feed; Animals; Betaine; Carotenoids; Chickens; Coccidiosis; Coccidiostats; Diet; Drug Interac

1997
Hepatic and renal betaine-homocysteine methyltransferase activity in pigs as affected by dietary intakes of sulfur amino acids, choline, and betaine.
    Journal of animal science, 1998, Volume: 76, Issue:2

    Topics: Amino Acids, Sulfur; Animal Feed; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Chicke

1998
Interactive effects of betaine, crude protein, and net energy in finishing pigs.
    Journal of animal science, 1998, Volume: 76, Issue:9

    Topics: Administration, Oral; Animal Feed; Animals; Betaine; Blood Proteins; Blood Urea Nitrogen; Diet; Diet

1998
The effect of dietary betaine in Eimeria acervulina-infected chicks.
    Poultry science, 2000, Volume: 79, Issue:1

    Topics: Animal Nutritional Physiological Phenomena; Animals; Betaine; Blood Proteins; Carotenoids; Chickens;

2000
Influence of dietary protein level on the broiler chicken's response to methionine and betaine supplements.
    Poultry science, 2000, Volume: 79, Issue:10

    Topics: Adipose Tissue; Animals; Betaine; Body Composition; Chickens; Diet; Dietary Proteins; Dietary Supple

2000
Can betaine partially replace or enhance the effect of methionine by improving broiler growth and carcase characteristics?
    British poultry science, 2000, Volume: 41, Issue:4

    Topics: Adipose Tissue; Amino Acids; Animals; Betaine; Chickens; Chromatography, High Pressure Liquid; Chrom

2000
Betaine does not improve performance of laying hens when the diet contains adequate choline.
    Poultry science, 2002, Volume: 81, Issue:1

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Betaine; Chickens; Choline; Eggs;

2002