betaine has been researched along with Spastic Paraplegia, Hereditary in 1 studies
glycine betaine : The amino acid betaine derived from glycine.
Spastic Paraplegia, Hereditary: A group of inherited diseases that share similar phenotypes but are genetically diverse. Different genetic loci for autosomal recessive, autosomal dominant, and x-linked forms of hereditary spastic paraplegia have been identified. Clinically, patients present with slowly progressive distal limb weakness and lower extremity spasticity. Peripheral sensory neurons may be affected in the later stages of the disease. (J Neurol Neurosurg Psychiatry 1998 Jan;64(1):61-6; Curr Opin Neurol 1997 Aug;10(4):313-8)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with betaine produced a rapid decline of homocysteine by 50% to 70% in all 4 patients and, over 9 to 15 years, improved the conditions of the 3 ambulatory patients." | 1.40 | Severe methylenetetrahydrofolate reductase deficiency: clinical clues to a potentially treatable cause of adult-onset hereditary spastic paraplegia. ( Abramsky, O; Gal, A; Heyman, SN; Karp, N; Kohn, Y; Korman, SH; Leclerc, D; Lossos, A; Meiner, V; Milman, T; Newman, JP; Rosenblatt, DS; Rozen, R; Schwahn, BC; Shaag, A; Steiner-Birmanns, B; Teltsh, O; Watkins, D, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lossos, A | 1 |
| Teltsh, O | 1 |
| Milman, T | 1 |
| Meiner, V | 1 |
| Rozen, R | 1 |
| Leclerc, D | 1 |
| Schwahn, BC | 1 |
| Karp, N | 1 |
| Rosenblatt, DS | 1 |
| Watkins, D | 1 |
| Shaag, A | 1 |
| Korman, SH | 1 |
| Heyman, SN | 1 |
| Gal, A | 1 |
| Newman, JP | 1 |
| Steiner-Birmanns, B | 1 |
| Abramsky, O | 1 |
| Kohn, Y | 1 |
1 other study available for betaine and Spastic Paraplegia, Hereditary
| Article | Year |
|---|---|
Severe methylenetetrahydrofolate reductase deficiency: clinical clues to a potentially treatable cause of adult-onset hereditary spastic paraplegia.
Topics: Adult; Age of Onset; Aged; Betaine; Female; Homocystinuria; Humans; Lipotropic Agents; Magnetic Reso | 2014 |