Page last updated: 2024-10-16

betaine and Machado-Joseph Disease

betaine has been researched along with Machado-Joseph Disease in 1 studies

glycine betaine : The amino acid betaine derived from glycine.

Machado-Joseph Disease: A dominantly-inherited ATAXIA first described in people of Azorean and Portuguese descent, and subsequently identified in Brazil, Japan, China, and Australia. This disorder is classified as one of the SPINOCEREBELLAR ATAXIAS (Type 3) and has been associated with a mutation of the MJD1 gene on chromosome 14. Clinical features include progressive ataxia, DYSARTHRIA, postural instability, nystagmus, eyelid retraction, and facial FASCICULATIONS. DYSTONIA is prominent in younger patients (referred to as Type I Machado-Joseph Disease). Type II features ataxia and ocular signs; Type III features MUSCULAR ATROPHY and a sensorimotor neuropathy; and Type IV features extrapyramidal signs combined with a sensorimotor neuropathy. (From Clin Neurosci 1995;3(1):17-22; Ann Neurol 1998 Mar;43(3):288-96)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Furusho, K1
Yoshizawa, T1
Shoji, S1

Other Studies

1 other study available for betaine and Machado-Joseph Disease

ArticleYear
Ectoine alters subcellular localization of inclusions and reduces apoptotic cell death induced by the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch.
    Neurobiology of disease, 2005, Volume: 20, Issue:1

    Topics: Amino Acids, Diamino; Animals; Apoptosis; Ataxin-3; Betaine; Cell Line, Tumor; Cell Nucleus; Cytopla

2005