betaine has been researched along with Liver Neoplasms in 16 studies
glycine betaine : The amino acid betaine derived from glycine.
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The dietary intakes of choline and betaine have been related to the mortality of some neoplasms, but their effects on hepatocellular carcinoma (HCC) mortality are still unknown." | 7.96 | Dietary choline, rather than betaine intake, is associated with hepatocellular carcinoma mortality. ( Fang, AP; Liu, ZY; Luo, Y; Yishake, D; Zhang, DM; Zhu, HL, 2020) |
| "PET with [methyl-(11)C]-choline (11C-choline) can be useful for detecting well-differentiated hepatocellular carcinoma (HCC) that is not 18F-FDG-avid." | 7.77 | Imaging lipid synthesis in hepatocellular carcinoma with [methyl-11c]choline: correlation with in vivo metabolic studies. ( Corn, DJ; Kolthammer, JA; Kuang, Y; Lee, Z; Salem, N; Tian, H; Wang, F; Wang, Y; Wu, C, 2011) |
| "Early diagnosis of hepatocellular carcinoma (HCC) remains challenging to date." | 5.42 | Metabolomics Identifies Biomarker Pattern for Early Diagnosis of Hepatocellular Carcinoma: from Diethylnitrosamine Treated Rats to Patients. ( Hu, C; Huang, X; Lin, X; Niu, J; Tan, Y; Wang, H; Wang, X; Yin, P; Zeng, J; Zhou, L, 2015) |
| "The dietary intakes of choline and betaine have been related to the mortality of some neoplasms, but their effects on hepatocellular carcinoma (HCC) mortality are still unknown." | 3.96 | Dietary choline, rather than betaine intake, is associated with hepatocellular carcinoma mortality. ( Fang, AP; Liu, ZY; Luo, Y; Yishake, D; Zhang, DM; Zhu, HL, 2020) |
| "PET with [methyl-(11)C]-choline (11C-choline) can be useful for detecting well-differentiated hepatocellular carcinoma (HCC) that is not 18F-FDG-avid." | 3.77 | Imaging lipid synthesis in hepatocellular carcinoma with [methyl-11c]choline: correlation with in vivo metabolic studies. ( Corn, DJ; Kolthammer, JA; Kuang, Y; Lee, Z; Salem, N; Tian, H; Wang, F; Wang, Y; Wu, C, 2011) |
| "SAM reduces colorectal cancer progression and inhibits the proliferation of preneoplastic rat liver cells in vivo." | 2.82 | S-Adenosylmethionine: From the Discovery of Its Inhibition of Tumorigenesis to Its Use as a Therapeutic Agent. ( Calvisi, DF; Feo, CF; Feo, F; Pascale, RM; Simile, MM, 2022) |
| "Choline deficiency has been well studied in the context of liver disease; however, less is known about the effects of choline supplementation in HCC." | 1.56 | Dietary Choline Supplementation Attenuates High-Fat-Diet-Induced Hepatocellular Carcinoma in Mice. ( Allende, DS; Brown, AL; Conrad, K; Gromovsky, AD; Helsley, RN; Neumann, CK; Owens, AP; Tranter, M; Zhang, R, 2020) |
| "Early diagnosis of hepatocellular carcinoma (HCC) remains challenging to date." | 1.42 | Metabolomics Identifies Biomarker Pattern for Early Diagnosis of Hepatocellular Carcinoma: from Diethylnitrosamine Treated Rats to Patients. ( Hu, C; Huang, X; Lin, X; Niu, J; Tan, Y; Wang, H; Wang, X; Yin, P; Zeng, J; Zhou, L, 2015) |
| "Hepatocellular carcinoma has a poor prognosis due to its rapid development and early metastasis." | 1.39 | Metabolic characterization of hepatocellular carcinoma using nontargeted tissue metabolomics. ( Gao, P; Huang, Q; Lu, X; Tan, Y; Wang, H; Xu, G; Ye, G; Yin, P, 2013) |
| "The development and progression of liver cancer may involve abnormal changes in DNA methylation, which lead to the activation of certain proto-oncogenes, such as c-myc, as well as the inactivation of certain tumor suppressors, such as p16." | 1.35 | Assessment of the effect of betaine on p16 and c-myc DNA methylation and mRNA expression in a chemical induced rat liver cancer model. ( Du, YP; Ling, WH; Peng, JS; Sun, A; Tang, ZH; Zhu, HL, 2009) |
| "A betaine treatment protected primary mouse hepatocytes from a homocysteine-induced increase in GRP78 and cell death but not a tunicamycin-induced increase." | 1.34 | Mechanisms of protection by the betaine-homocysteine methyltransferase/betaine system in HepG2 cells and primary mouse hepatocytes. ( Chan, C; Ji, C; Kaplowitz, N; Kuhlenkamp, J; Shinohara, M, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 7 (43.75) | 24.3611 |
| 2020's | 3 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| Pascale, RM | 1 |
| Simile, MM | 1 |
| Calvisi, DF | 1 |
| Feo, CF | 1 |
| Feo, F | 1 |
| Brown, AL | 1 |
| Conrad, K | 1 |
| Allende, DS | 1 |
| Gromovsky, AD | 1 |
| Zhang, R | 1 |
| Neumann, CK | 1 |
| Owens, AP | 1 |
| Tranter, M | 1 |
| Helsley, RN | 1 |
| Liu, ZY | 1 |
| Zhang, DM | 1 |
| Yishake, D | 1 |
| Luo, Y | 1 |
| Fang, AP | 1 |
| Zhu, HL | 3 |
| Zhou, RF | 1 |
| Chen, XL | 1 |
| Zhou, ZG | 1 |
| Zhang, YJ | 1 |
| Lan, QY | 1 |
| Liao, GC | 1 |
| Chen, YM | 1 |
| Zeisel, S | 1 |
| Huang, Q | 1 |
| Tan, Y | 2 |
| Yin, P | 2 |
| Ye, G | 1 |
| Gao, P | 2 |
| Lu, X | 1 |
| Wang, H | 2 |
| Xu, G | 2 |
| Zeng, J | 1 |
| Huang, X | 1 |
| Zhou, L | 1 |
| Hu, C | 1 |
| Wang, X | 1 |
| Niu, J | 1 |
| Lin, X | 1 |
| Oliva, J | 2 |
| Bardag-Gorce, F | 2 |
| French, BA | 1 |
| Li, J | 1 |
| French, SW | 2 |
| Du, YP | 1 |
| Peng, JS | 1 |
| Sun, A | 1 |
| Tang, ZH | 1 |
| Ling, WH | 1 |
| Kuang, Y | 1 |
| Salem, N | 1 |
| Tian, H | 1 |
| Kolthammer, JA | 1 |
| Corn, DJ | 1 |
| Wu, C | 1 |
| Wang, F | 1 |
| Wang, Y | 2 |
| Lee, Z | 1 |
| Tillman, B | 1 |
| Pellanda, H | 1 |
| Namour, F | 1 |
| Fofou-Caillierez, M | 1 |
| Bressenot, A | 1 |
| Alberto, JM | 1 |
| Chéry, C | 1 |
| Ayav, A | 1 |
| Bronowicki, JP | 1 |
| Guéant, JL | 1 |
| Forges, T | 1 |
| Schäfer, C | 1 |
| Hoffmann, L | 1 |
| Heldt, K | 1 |
| Lornejad-Schäfer, MR | 1 |
| Brauers, G | 1 |
| Gehrmann, T | 1 |
| Garrow, TA | 1 |
| Häussinger, D | 1 |
| Mayatepek, E | 1 |
| Schwahn, BC | 1 |
| Schliess, F | 1 |
| Ji, C | 1 |
| Shinohara, M | 1 |
| Kuhlenkamp, J | 1 |
| Chan, C | 1 |
| Kaplowitz, N | 1 |
| Wang, T | 1 |
| Shi, X | 1 |
| Wan, D | 1 |
| Zhang, P | 1 |
| He, X | 1 |
| Yang, S | 1 |
| Gu, J | 1 |
| Poirier, LA | 1 |
2 reviews available for betaine and Liver Neoplasms
| Article | Year |
|---|---|
S-Adenosylmethionine: From the Discovery of Its Inhibition of Tumorigenesis to Its Use as a Therapeutic Agent.
Topics: Animals; Antiviral Agents; Betaine; Carcinogenesis; Carcinoma, Hepatocellular; Cell Transformation, | 2022 |
Choline, Other Methyl-Donors and Epigenetics.
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Cyclin-Dependent Kinase Inhibit | 2017 |
14 other studies available for betaine and Liver Neoplasms
| Article | Year |
|---|---|
Dietary Choline Supplementation Attenuates High-Fat-Diet-Induced Hepatocellular Carcinoma in Mice.
Topics: Animals; Betaine; Choline; Diet, High-Fat; Dietary Supplements; DNA, Mitochondrial; Fatty Liver; Gen | 2020 |
Dietary choline, rather than betaine intake, is associated with hepatocellular carcinoma mortality.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Betaine; Carcinoma, Hepatocellular; China; Choline; Diet | 2020 |
Higher dietary intakes of choline and betaine are associated with a lower risk of primary liver cancer: a case-control study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Betaine; Case-Control Studies; China; Choline; Diet; Fem | 2017 |
Metabolic characterization of hepatocellular carcinoma using nontargeted tissue metabolomics.
Topics: Adult; Aged; Antioxidants; Betaine; Carcinoma, Hepatocellular; Carnitine; Citric Acid Cycle; Fatty A | 2013 |
Metabolomics Identifies Biomarker Pattern for Early Diagnosis of Hepatocellular Carcinoma: from Diethylnitrosamine Treated Rats to Patients.
Topics: alpha-Fetoproteins; Animals; Betaine; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cohort Studies; | 2015 |
The regulation of non-coding RNA expression in the liver of mice fed DDC.
Topics: Animals; Betaine; Biomarkers, Tumor; Diet; Dihydropyridines; Gene Expression Profiling; Gene Express | 2009 |
Assessment of the effect of betaine on p16 and c-myc DNA methylation and mRNA expression in a chemical induced rat liver cancer model.
Topics: Animals; Betaine; Cyclin-Dependent Kinase Inhibitor p16; Diethylnitrosamine; DNA Methylation; Dose-R | 2009 |
Imaging lipid synthesis in hepatocellular carcinoma with [methyl-11c]choline: correlation with in vivo metabolic studies.
Topics: Animals; Betaine; Carbon Radioisotopes; Carcinoma, Hepatocellular; Choline; Choline Kinase; Choline- | 2011 |
Protective effect of quercetin, EGCG, catechin and betaine against oxidative stress induced by ethanol in vitro.
Topics: Aldehydes; Anti-Infective Agents, Local; Antioxidants; Betaine; Blotting, Western; Carcinoma, Hepato | 2011 |
A splicing variant leads to complete loss of function of betaine-homocysteine methyltransferase (BHMT) gene in hepatocellular carcinoma.
Topics: Alternative Splicing; Betaine; Betaine-Homocysteine S-Methyltransferase; Carcinoma, Hepatocellular; | 2012 |
Osmotic regulation of betaine homocysteine-S-methyltransferase expression in H4IIE rat hepatoma cells.
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Carcinoma, Hepatocellular; Cell Line, Tu | 2007 |
Mechanisms of protection by the betaine-homocysteine methyltransferase/betaine system in HepG2 cells and primary mouse hepatocytes.
Topics: Animals; Apolipoproteins B; Betaine; Betaine-Homocysteine S-Methyltransferase; Carcinoma, Hepatocell | 2007 |
Analysis of acetylcholine, choline and butyrobetaine in human liver tissues by hydrophilic interaction liquid chromatography-tandem mass spectrometry.
Topics: Acetylcholine; Betaine; Carcinoma, Hepatocellular; Carnitine; Choline; Chromatography, Liquid; Human | 2008 |
Hepatocarcinogenesis by diethylnitrosamine in rats fed high dietary levels of lipotropes.
Topics: Animals; Betaine; Carcinogens; Carcinoma, Hepatocellular; Choline; Diet; Ethanolamines; Folic Acid; | 1975 |