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betaine and Liver Diseases, Alcoholic

betaine has been researched along with Liver Diseases, Alcoholic in 17 studies

glycine betaine : The amino acid betaine derived from glycine.

Liver Diseases, Alcoholic: Liver diseases associated with ALCOHOLISM. It usually refers to the coexistence of two or more subentities, i.e., ALCOHOLIC FATTY LIVER; ALCOHOLIC HEPATITIS; and ALCOHOLIC CIRRHOSIS.

Research Excerpts

ExcerptRelevanceReference
" The focus should be on the long-term use of betaine in large patient populations with liver diseases characterized by development of fatty liver, especially non-alcoholic fatty liver disease and alcoholic liver disease."4.93Betaine chemistry, roles, and potential use in liver disease. ( Day, CR; Kempson, SA, 2016)
" The proximate cause appears to be hyperhomocysteinemia, a well-known cause of ER stress in other contexts."4.83Unfolding new mechanisms of alcoholic liver disease in the endoplasmic reticulum. ( Ji, C; Kaplowitz, N, 2006)
"Betaine is a kind of water-soluble quaternary amine-type alkaloid widely existing in food, such as wheat germ, beet, spinach, shrimp and wolfberry."2.72Preventive and therapeutic role of betaine in liver disease: A review on molecular mechanisms. ( Dai, S; Gong, L; Li, Y; Ma, C; Wang, C, 2021)
"Betaine was administered intragastrically after exposure of ethanol for 4 wk."1.36Betaine inhibits toll-like receptor 4 expression in rats with ethanol-induced liver injury. ( Gong, ZJ; Shi, QZ; Wang, LW; Zhang, W, 2010)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (47.06)29.6817
2010's8 (47.06)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Wang, C1
Ma, C1
Gong, L1
Dai, S1
Li, Y1
Jung, YS2
Kim, SJ2
Kwon, DY2
Ahn, CW1
Kim, YS1
Choi, DW1
Kim, YC2
Dou, X1
Xia, Y1
Chen, J1
Qian, Y1
Li, S1
Zhang, X1
Song, Z2
French, SW1
Day, CR1
Kempson, SA1
Kharbanda, KK6
Vigneswara, V1
McVicker, BL1
Newlaczyl, AU1
Bailey, K1
Tuma, D1
Ray, DE1
Carter, WG1
Powell, CL1
Bradford, BU1
Craig, CP1
Tsuchiya, M1
Uehara, T1
O'Connell, TM1
Pogribny, IP1
Melnyk, S1
Koop, DR1
Bleyle, L1
Threadgill, DW1
Rusyn, I1
Shi, QZ1
Wang, LW1
Zhang, W1
Gong, ZJ1
Bardag-Gorce, F1
Barve, S2
Molina, PE1
Osna, NA1
Kaplowitz, N2
Ji, C1
Purohit, V1
Abdelmalek, MF1
Benevenga, NJ1
Halsted, CH1
Liu, QY1
Lu, SC1
McClain, CJ2
Swanson, C1
Zakhari, S1
Zhou, Z1
Deaciuc, I1
Chen, T1

Reviews

9 reviews available for betaine and Liver Diseases, Alcoholic

ArticleYear
Preventive and therapeutic role of betaine in liver disease: A review on molecular mechanisms.
    European journal of pharmacology, 2021, Dec-05, Volume: 912

    Topics: Animals; Betaine; Chemical and Drug Induced Liver Injury; Humans; Liver Diseases; Liver Diseases, Al

2021
How to prevent alcoholic liver disease.
    Experimental and molecular pathology, 2015, Volume: 98, Issue:2

    Topics: Alcoholism; Animals; Betaine; Energy Metabolism; Epinephrine; Ethanol; Humans; Liver; Liver Diseases

2015
Betaine chemistry, roles, and potential use in liver disease.
    Biochimica et biophysica acta, 2016, Volume: 1860, Issue:6

    Topics: Animals; Betaine; Humans; Kidney; Liver; Liver Diseases; Liver Diseases, Alcoholic; Non-alcoholic Fa

2016
Alcoholic liver disease and methionine metabolism.
    Seminars in liver disease, 2009, Volume: 29, Issue:2

    Topics: Alcohol Drinking; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Ethanol; Homocysteine;

2009
Impact of altered methylation in cytokine signaling and proteasome function in alcohol and viral-mediated diseases.
    Alcoholism, clinical and experimental research, 2013, Volume: 37, Issue:1

    Topics: Animals; Antigen Presentation; Betaine; Ethanol; Hepatitis C; Humans; Interferons; Liver; Liver Dise

2013
Methionine metabolic pathway in alcoholic liver injury.
    Current opinion in clinical nutrition and metabolic care, 2013, Volume: 16, Issue:1

    Topics: Aminobutyrates; Betaine; Biomarkers; Cystathionine; Ethanol; Humans; Liver; Liver Diseases, Alcoholi

2013
Unfolding new mechanisms of alcoholic liver disease in the endoplasmic reticulum.
    Journal of gastroenterology and hepatology, 2006, Volume: 21 Suppl 3

    Topics: Animals; Betaine; Endoplasmic Reticulum; Gastrointestinal Agents; Gene Expression Profiling; Glutath

2006
Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: summary of a symposium.
    The American journal of clinical nutrition, 2007, Volume: 86, Issue:1

    Topics: Animals; Betaine; Disease Models, Animal; Folic Acid; Humans; Liver Diseases, Alcoholic; Methionine;

2007
Role of transmethylation reactions in alcoholic liver disease.
    World journal of gastroenterology, 2007, Oct-07, Volume: 13, Issue:37

    Topics: Betaine; Humans; Lipotropic Agents; Liver Diseases, Alcoholic; Methionine; Methyltransferases; S-Ade

2007

Other Studies

8 other studies available for betaine and Liver Diseases, Alcoholic

ArticleYear
Alleviation of alcoholic liver injury by betaine involves an enhancement of antioxidant defense via regulation of sulfur amino acid metabolism.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 62

    Topics: Amino Acids, Sulfur; Animals; Antioxidants; Betaine; Body Weight; Cyclooxygenase 2; Cysteine; Cytoso

2013
Rectification of impaired adipose tissue methylation status and lipolytic response contributes to hepatoprotective effect of betaine in a mouse model of alcoholic liver disease.
    British journal of pharmacology, 2014, Volume: 171, Issue:17

    Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Betaine; Cells, Cultured; Cytoprotection; Disease Models, Ani

2014
Proteomics reveal a concerted upregulation of methionine metabolic pathway enzymes, and downregulation of carbonic anhydrase-III, in betaine supplemented ethanol-fed rats.
    Biochemical and biophysical research communications, 2009, Apr-17, Volume: 381, Issue:4

    Topics: Animals; Betaine; Carbonic Anhydrase III; Down-Regulation; Ethanol; Glycine N-Methyltransferase; Hom

2009
Mechanism for prevention of alcohol-induced liver injury by dietary methyl donors.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 115, Issue:1

    Topics: Aldehyde Dehydrogenase; Animals; Betaine; Catalase; Central Nervous System Depressants; Cytochrome P

2010
Betaine inhibits toll-like receptor 4 expression in rats with ethanol-induced liver injury.
    World journal of gastroenterology, 2010, Feb-21, Volume: 16, Issue:7

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Betaine; Biomarkers; Blotting, Western;

2010
Betaine. Monograph.
    Alternative medicine review : a journal of clinical therapeutic, 2003, Volume: 8, Issue:2

    Topics: Betaine; Cardiovascular Diseases; Fatty Liver; Homocysteine; Homocystinuria; Humans; Hyperhomocystei

2003
Inhibition of adiponectin production by homocysteine: a potential mechanism for alcoholic liver disease.
    Hepatology (Baltimore, Md.), 2008, Volume: 47, Issue:3

    Topics: Adiponectin; Adipose Tissue; Animals; Betaine; Cystathionine beta-Synthase; Disease Models, Animal;

2008
Alleviation of acute ethanol-induced liver injury and impaired metabolomics of S-containing substances by betaine supplementation.
    Biochemical and biophysical research communications, 2008, Apr-18, Volume: 368, Issue:4

    Topics: Alanine Transaminase; Amino Acids, Sulfur; Animals; Betaine; Cytochrome P-450 CYP2E1; Ethanol; Lipid

2008