Page last updated: 2024-10-16

betaine and Kidney Diseases

betaine has been researched along with Kidney Diseases in 15 studies

glycine betaine : The amino acid betaine derived from glycine.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"Our study aimed to investigate the role of betaine in the modulation of MIF-mediated oxidative stress, inflammation, and fibrogenesis during toxic kidney damage induced by thioacetamide (TAA)."8.12Betaine Modulating MIF-Mediated Oxidative Stress, Inflammation and Fibrogenesis in Thioacetamide-Induced Nephrotoxicity. ( Filipović, J; Jorgačević, B; Radosavljević, T; Samardžić, J; Stanković, S; Vučević, D, 2022)
"Our study aimed to investigate the role of betaine in the modulation of MIF-mediated oxidative stress, inflammation, and fibrogenesis during toxic kidney damage induced by thioacetamide (TAA)."4.12Betaine Modulating MIF-Mediated Oxidative Stress, Inflammation and Fibrogenesis in Thioacetamide-Induced Nephrotoxicity. ( Filipović, J; Jorgačević, B; Radosavljević, T; Samardžić, J; Stanković, S; Vučević, D, 2022)
"Betaine has been shown to protect internal organs, improve vascular risk factors, and enhance performance."2.42Betaine in human nutrition. ( Craig, SA, 2004)
"Betaine treatment significantly attenuated arsenic-induced decrease in renal eNOS expression."1.72Betaine attenuates sodium arsenite-induced renal dysfunction in rats. ( Kaur, T; Pathak, D; Sharma, AK; Sharma, S; Singh, AP; Singh, B; Yadav, HN, 2022)
" These findings suggest that betaine and melatonin concomitant use is likely to provide greater protection against CP-induced nephrotoxicity than when they are given singly, rendering them potentially suitable and safe agents to use in clinical trials to assess their possible beneficial actions in cancer patients receiving CP."1.62The salutary action of melatonin and betaine, given singly or concomitantly, on cisplatin-induced nephrotoxicity in mice. ( Al Sabahi, M; Al Za'abi, M; Ali, BH; Ali, H, 2021)
"Betaine is a natural trimethylglycine compound involved in several biological reactions."1.62Betaine downregulates microRNA 34a expression via a p53-dependent manner in cisplatin-induced nephrotoxicity in rats. ( Al-Dalain, SM; Hussein, RM, 2021)
" Its primary dose-limiting side effect is nephrotoxicity."1.42Betaine supplementation mitigates cisplatin-induced nephrotoxicity by abrogation of oxidative/nitrosative stress and suppression of inflammation and apoptosis in rats. ( Hagar, H; Medany, AE; Medany, GE; Nayal, OA; Salam, R, 2015)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19902 (13.33)18.7374
1990's1 (6.67)18.2507
2000's3 (20.00)29.6817
2010's3 (20.00)24.3611
2020's6 (40.00)2.80

Authors

AuthorsStudies
Rosas-Rodríguez, JA1
Valenzuela-Soto, EM1
Jorgačević, B1
Stanković, S1
Filipović, J1
Samardžić, J1
Vučević, D1
Radosavljević, T1
Pourmehdi, A1
Sakhaei, Z1
Alirezaei, M1
Dezfoulian, O1
Al Za'abi, M1
Ali, H1
Al Sabahi, M1
Ali, BH1
Hussein, RM1
Al-Dalain, SM1
Sharma, S1
Kaur, T1
Sharma, AK1
Singh, B1
Pathak, D1
Yadav, HN1
Singh, AP1
Zou, ZJ1
Xie, YY1
Gong, MJ1
Han, B1
Wang, SM1
Liang, SW1
Hagar, H1
Medany, AE1
Salam, R1
Medany, GE1
Nayal, OA1
Ocque, AJ1
Stubbs, JR1
Nolin, TD1
Gotloib, L1
ENGEL, RW1
Ozturk, F1
Ucar, M1
Ozturk, IC1
Vardi, N1
Batcioglu, K1
MULFORD, DJ1
Craig, SA1
Lever, M1
Sizeland, PC1
Bason, LM1
Hayman, CM1
Robson, RA1
Chambers, ST1

Reviews

3 reviews available for betaine and Kidney Diseases

ArticleYear
The glycine betaine role in neurodegenerative, cardiovascular, hepatic, and renal diseases: Insights into disease and dysfunction networks.
    Life sciences, 2021, Nov-15, Volume: 285

    Topics: Betaine; Cardiovascular Diseases; Cell Size; Humans; Hyperhomocysteinemia; Kidney Diseases; Liver Di

2021
Preservation and modulation of peritoneal function. A potential role of pyruvate and betaine.
    Contributions to nephrology, 2009, Volume: 163

    Topics: Betaine; Chronic Disease; Humans; Kidney Diseases; Oxidative Stress; Peritoneal Dialysis; Peritoneum

2009
Betaine in human nutrition.
    The American journal of clinical nutrition, 2004, Volume: 80, Issue:3

    Topics: Animals; Betaine; Cardiovascular Diseases; DNA Methylation; Gastrointestinal Agents; Humans; Hyperho

2004

Trials

1 trial available for betaine and Kidney Diseases

ArticleYear
Abnormal glycine betaine content of the blood and urine of diabetic and renal patients.
    Clinica chimica acta; international journal of clinical chemistry, 1994, Oct-14, Volume: 230, Issue:1

    Topics: Adult; Albuminuria; Betaine; Chromatography, High Pressure Liquid; Creatinine; Diabetes Mellitus; Fe

1994

Other Studies

11 other studies available for betaine and Kidney Diseases

ArticleYear
Betaine Modulating MIF-Mediated Oxidative Stress, Inflammation and Fibrogenesis in Thioacetamide-Induced Nephrotoxicity.
    Current medicinal chemistry, 2022, 08-15, Volume: 29, Issue:31

    Topics: Animals; Antioxidants; Becaplermin; Betaine; Glutathione; Inflammation; Interleukin-6; Kidney Diseas

2022
Betaine effects against asthma-induced oxidative stress in the liver and kidney of mice.
    Molecular biology reports, 2020, Volume: 47, Issue:8

    Topics: Animals; Antioxidants; Asthma; Betaine; Disease Models, Animal; Female; Glucocorticoids; Inflammatio

2020
The salutary action of melatonin and betaine, given singly or concomitantly, on cisplatin-induced nephrotoxicity in mice.
    Naunyn-Schmiedeberg's archives of pharmacology, 2021, Volume: 394, Issue:8

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Betaine; Cisplatin; Drug Therapy, Combination;

2021
Betaine downregulates microRNA 34a expression via a p53-dependent manner in cisplatin-induced nephrotoxicity in rats.
    Journal of biochemical and molecular toxicology, 2021, Volume: 35, Issue:9

    Topics: Animals; Betaine; Cisplatin; Down-Regulation; Kidney Diseases; Male; MicroRNAs; Rats; Rats, Wistar;

2021
Betaine attenuates sodium arsenite-induced renal dysfunction in rats.
    Drug and chemical toxicology, 2022, Volume: 45, Issue:6

    Topics: Animals; Antioxidants; Arsenic; Arsenites; Betaine; Creatinine; Glutathione; Hydroxyproline; Kidney

2022
[Urine metabonomic study of intervention effects of Morinda officinalis how. on 'kidney-yang deficiency syndrome'].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:11

    Topics: Alanine; Animals; Betaine; Biomarkers; Citric Acid; Drugs, Chinese Herbal; Hydrocortisone; Ketogluta

2013
Betaine supplementation mitigates cisplatin-induced nephrotoxicity by abrogation of oxidative/nitrosative stress and suppression of inflammation and apoptosis in rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2015, Volume: 67, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Betaine; Cisplatin; Dietary Supplements; Immunohistochemi

2015
Development and validation of a simple UHPLC-MS/MS method for the simultaneous determination of trimethylamine N-oxide, choline, and betaine in human plasma and urine.
    Journal of pharmaceutical and biomedical analysis, 2015, May-10, Volume: 109

    Topics: Betaine; Calibration; Choline; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents

2015
Relative effectiveness of choline, methionine, betaine, casein and egg albumen in preventing kidney hemorrhage.
    Federation proceedings, 1947, Volume: 6, Issue:1

    Topics: Albumins; Betaine; Caseins; Choline; Hemorrhage; Humans; Kidney; Kidney Diseases; Methionine

1947
Carbon tetrachloride-induced nephrotoxicity and protective effect of betaine in Sprague-Dawley rats.
    Urology, 2003, Volume: 62, Issue:2

    Topics: Animals; Betaine; Carbon Tetrachloride; Kidney; Kidney Diseases; Protective Agents; Rats; Rats, Spra

2003
Betaine and methionine on renal hemorrhagic degeneration in rats receiving 2-amino-2-methyl propanol-1.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1955, Volume: 89, Issue:3

    Topics: Amino Alcohols; Animals; Betaine; Choline; Glycine; Hemorrhage; Kidney; Kidney Diseases; Methionine;

1955