betaine has been researched along with Heart Failure in 7 studies
glycine betaine : The amino acid betaine derived from glycine.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Few studies have examined the associations of trimethylamine-N-oxide (TMAO) and its precursors (choline, betaine, dimethylglycine, and L-carnitine) with the risk of atrial fibrillation (AF) and heart failure (HF)." | 8.02 | Choline Metabolism and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Study. ( Alonso-Gómez, A; Bulló, M; Clish, C; Corella, D; Estruch, R; Fiol, M; Fitó, M; Guasch-Ferré, M; Hernández-Alonso, P; Hu, FB; Li, J; Liang, L; Martínez-González, MA; Papandreou, C; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Santos-Lozano, JM; Serra-Majem, L; Toledo, E, 2021) |
| "The highest and lowest quintiles of urinary betaine excretion associated with risk of heart failure (p = 0." | 7.78 | Betaine and secondary events in an acute coronary syndrome cohort. ( Atkinson, W; Chambers, ST; Elmslie, JL; Frampton, CM; George, PM; Lever, M; Molyneux, SL; Richards, AM; Slow, S; Troughton, RW, 2012) |
| "Few studies have examined the associations of trimethylamine-N-oxide (TMAO) and its precursors (choline, betaine, dimethylglycine, and L-carnitine) with the risk of atrial fibrillation (AF) and heart failure (HF)." | 4.02 | Choline Metabolism and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Study. ( Alonso-Gómez, A; Bulló, M; Clish, C; Corella, D; Estruch, R; Fiol, M; Fitó, M; Guasch-Ferré, M; Hernández-Alonso, P; Hu, FB; Li, J; Liang, L; Martínez-González, MA; Papandreou, C; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Santos-Lozano, JM; Serra-Majem, L; Toledo, E, 2021) |
| "Trimethylamine N-oxide (TMAO), a gut-related metabolite, is associated with heart failure (HF) outcomes." | 4.02 | Association of gut-related metabolites with outcome in acute heart failure. ( Bernieh, D; Cassambai, S; Heaney, LM; Israr, MZ; Jones, DJL; Ng, LL; Salzano, A; Suzuki, T; Yazaki, Y, 2021) |
| "The highest and lowest quintiles of urinary betaine excretion associated with risk of heart failure (p = 0." | 3.78 | Betaine and secondary events in an acute coronary syndrome cohort. ( Atkinson, W; Chambers, ST; Elmslie, JL; Frampton, CM; George, PM; Lever, M; Molyneux, SL; Richards, AM; Slow, S; Troughton, RW, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 4 (57.14) | 2.80 |
| Authors | Studies |
|---|---|
| Wargny, M | 1 |
| Croyal, M | 1 |
| Ragot, S | 1 |
| Gand, E | 1 |
| Jacobi, D | 1 |
| Trochu, JN | 1 |
| Prieur, X | 1 |
| Le May, C | 1 |
| Goronflot, T | 1 |
| Cariou, B | 1 |
| Saulnier, PJ | 1 |
| Hadjadj, S | 1 |
| Papandreou, C | 1 |
| Bulló, M | 1 |
| Hernández-Alonso, P | 1 |
| Ruiz-Canela, M | 1 |
| Li, J | 1 |
| Guasch-Ferré, M | 1 |
| Toledo, E | 1 |
| Clish, C | 1 |
| Corella, D | 1 |
| Estruch, R | 1 |
| Ros, E | 1 |
| Fitó, M | 1 |
| Alonso-Gómez, A | 1 |
| Fiol, M | 1 |
| Santos-Lozano, JM | 1 |
| Serra-Majem, L | 1 |
| Liang, L | 1 |
| Martínez-González, MA | 1 |
| Hu, FB | 1 |
| Salas-Salvadó, J | 1 |
| Israr, MZ | 1 |
| Bernieh, D | 1 |
| Salzano, A | 1 |
| Cassambai, S | 1 |
| Yazaki, Y | 1 |
| Heaney, LM | 1 |
| Jones, DJL | 1 |
| Ng, LL | 1 |
| Suzuki, T | 1 |
| Lv, Y | 1 |
| Ma, P | 2 |
| Wang, J | 1 |
| Xu, Q | 1 |
| Fan, J | 1 |
| Yan, L | 1 |
| Zhou, R | 1 |
| Trøseid, M | 1 |
| Ueland, T | 1 |
| Hov, JR | 1 |
| Svardal, A | 1 |
| Gregersen, I | 1 |
| Dahl, CP | 1 |
| Aakhus, S | 1 |
| Gude, E | 1 |
| Bjørndal, B | 1 |
| Halvorsen, B | 1 |
| Karlsen, TH | 1 |
| Aukrust, P | 1 |
| Gullestad, L | 1 |
| Berge, RK | 1 |
| Yndestad, A | 1 |
| Lever, M | 1 |
| George, PM | 1 |
| Elmslie, JL | 1 |
| Atkinson, W | 1 |
| Slow, S | 1 |
| Molyneux, SL | 1 |
| Troughton, RW | 1 |
| Richards, AM | 1 |
| Frampton, CM | 1 |
| Chambers, ST | 1 |
| BORSOOK, ME | 1 |
| BORSOOK, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| GutHeart: Targeting Gut Microbiota to Treat Heart Failure[NCT02637167] | Phase 2 | 150 participants (Anticipated) | Interventional | 2016-03-11 | Recruiting | ||
| The Effects of Medium-term Oral Guanidinoacetic Acid (GAA) Administration on Human Performance, Body Composition, and Metabolic Outcomes in Physically Active Men and Women[NCT01133899] | Phase 1/Phase 2 | 40 participants (Actual) | Interventional | 2010-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 other studies available for betaine and Heart Failure
| Article | Year |
|---|---|
Nutritional biomarkers and heart failure requiring hospitalization in patients with type 2 diabetes: the SURDIAGENE cohort.
Topics: Aged; Betaine; Biomarkers; Carnitine; Choline; Cohort Studies; Cysteine; Diabetes Mellitus, Type 2; | 2022 |
Choline Metabolism and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Study.
Topics: Aged; Atrial Fibrillation; Betaine; Carnitine; Case-Control Studies; Choline; Female; Heart Failure; | 2021 |
Association of gut-related metabolites with outcome in acute heart failure.
Topics: Acetylcarnitine; Acute Disease; Aged; Aged, 80 and over; Betaine; Carnitine; Choline; Female; Gastro | 2021 |
Betaine alleviates right ventricular failure via regulation of Rho A/ROCK signaling pathway in rats with pulmonary arterial hypertension.
Topics: Actins; Administration, Oral; Animals; Apoptosis; Arterioles; Betaine; Cardiotonic Agents; Disease M | 2021 |
Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure.
Topics: Aged; Betaine; Biomarkers; Choline; Chronic Disease; Female; Heart Failure; Humans; Intestinal Mucos | 2015 |
Betaine and secondary events in an acute coronary syndrome cohort.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Betaine; Chromatography, High Pressure Liquid; Coh | 2012 |
Treatment of cardiac decompensation with betaine and glycocyamine.
Topics: Betaine; Biochemical Phenomena; Cardiovascular Diseases; Creatine; Glycine; Heart Failure; Humans | 1951 |