betaine and Disease Models, Animal

betaine has been researched along with Disease Models, Animal in 87 studies

Research

Studies (87)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.15)18.7374
1990's3 (3.45)18.2507
2000's17 (19.54)29.6817
2010's51 (58.62)24.3611
2020's15 (17.24)2.80

Authors

AuthorsStudies
Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ1
Chan, MH; Chen, HH; Chen, LC; Chen, ST; Hsieh, CP; Huang, CM; Lee, MY1
Hiramatsu, M; Ibi, D; Kojima, Y; Kondo, S; Nakasai, G; Ohmi, A; Takaba, R1
Cao, W; Chen, L; Liang, Y; Liu, D; Liu, W; Mao, M; Wang, Y; Zhong, X1
Chen, C; Cui, J; He, Y; Hu, Y; Jing, T; Liu, E; Wang, S; Xu, H; Yang, Y; Zhao, N1
Feiten, AF; Ittner, LM; Ke, YD; Sontag, E; Sontag, JM; Taleski, G; van Hummel, A1
Jiang, YP; Liu, N; Liu, P; Ma, L; Niu, JG; Yang, JM; Ye, RJ; Yu, JQ; Zhang, WJ; Zheng, P1
Jadžić, J; Jorgačević, B; Labudović-Borović, M; Mladenović, D; Radosavljević, T; Vesković, M; Vučević, D; Vukićević, D1
Alirezaei, M; Dezfoulian, O; Pourmehdi, A; Sakhaei, Z1
Chen, Y; Cheng, Y; Liang, J; Lu, R; Song, S; Yan, K; Yuan, Y; Zha, Y; Zhang, T; Zhuang, W1
Chen, Q; Gong, Z; Jiao, F; Pei, M; Shi, C; Wang, L; Wang, Y1
Ando, T; Hiramatsu, M; Hirashima, K; Ibi, D; Kojima, Y; Kondo, S; Sumiya, K; Yamamoto, M1
Jiang, H; Maclean, KN; Mclagan, BM; Phinney, WN; Roede, JR; Stabler, SP1
Hirokawa, N; Ichinose, S; Jiang, X; Kakita, A; Kunii, Y; Morikawa, M; Ogawa, T; Tanaka, Y; Toyoshima, M; Yabe, H; Yoshihara, S; Yoshikawa, T1
Fan, J; Lv, Y; Ma, P; Wang, J; Xu, Q; Yan, L; Zhou, R1
Huang, T; Jia, M; Li, Y; Liu, S; Luo, Z; Miao, W; Song, Z; Wang, P; Wu, T; Yu, J; Yu, L; Zhang, H; Zhou, L1
Chen, FA; Chien, KJ; Horng, CT; Hsieh, YH; Huang, YS; Lu, CC; Wang, CJ; Yang, JS1
Jorgačević, B; Labudović-Borović, M; Mladenović, D; Radosavljević, T; Rakočević, J; Vesković, M; Vučević, D; Zaletel, I1
Abobaker, H; Hou, Z; Hu, Y; Omer, NA; Sun, Q; Zhao, R; Zong, Y1
Bouchard, M; Shiels, SM; Wang, H; Wenke, JC1
Ahmadi, A; Azarpira, N; Farshad, O; Ghanbarinejad, V; Heidari, R; Hosseini, A; Jamshidzadeh, A; Khodaei, F; Mohammadi, H; Najibi, A; Niknahad, H; Ommati, MM; Rashidi, E; Sadeghi, A; Siavashpour, A1
Tan, HR; Yang, JM; Yu, JQ; Zhang, M; Zhou, R1
Axen, K; Blain, K; Bretter, R; Jack-Roberts, C; Jiang, X; Jones, N; Nanobashvili, K; Saxena, A1
Crego, AL; Kammeijer, GSM; Marina, ML; Mayboroda, OA; Peters, DJM; Ramautar, R; Sánchez-López, E1
Hurt, KJ; Jiang, H; Keating, AK; Maclean, KN; Phinney, WN; Stabler, SP1
Chen, X; Chen, Z; Cui, C; Huang, F; Jiang, X; Niu, J; Sun, J1
Chakraborty, N; Donohue, D; Gautam, A; Hammamieh, R; Hoke, A; Jett, M; Miller, SA; Muhie, S1
Drobny, A; Fitzenberger, E; Hellmann, B; Meloh, H; Mueller, AS; van der Klis, JD; Wächtershäuser, E; Wenzel, U1
Balan, S; Esaki, K; Fujita, Y; Hashimoto, K; Hayashi-Takagi, A; Hino, M; Hisano, Y; Iwayama, Y; Kakita, A; Kunii, Y; Maekawa, M; Mataga, N; Matsumoto, J; Nagaoka, A; Nozaki, Y; Ohba, H; Ohnishi, T; Shimamoto-Mitsuyama, C; Tan, Y; Toyoshima, M; Watanabe, A; Yabe, H; Yoshikawa, T1
Baeza, I; Claus, SP; de Castro, NM; de la Fuente, M; Yaqoob, P1
Delaney, C; Hewagama, A; Hoeltzel, MF; Johnson, K; Mickelson, B; Richardson, BC; Sawalha, AH; Strickland, FM; Wu, A; Yung, R1
Chang, Y; Chen, SH; Hou, CC; Huang, J; Jhong, JF; Venault, A; Wei, TC; Zheng, J1
Bhattacharjee, PS; Clement, C; Foster, TP; Hill, JM; Lukiw, WJ; Malamud, D; McFerrin, HE; Ochoa, AC; Rodriguez, P; Stern, EM; Velasco, C1
Chen, Q; Chen, W; Garrett, Q; Hou, C; Li, J; Wang, Y; Zhang, X1
Obeid, R1
Fan, CY; Kong, LD; Li, JM; Liu, YL; Pan, Y; Wang, SJ; Wang, X; Zhu, Q1
Bahous, RH; Bedell, BJ; Caudill, MA; Deng, L; Grand'maison, M; Jadavji, NM; Malysheva, O; Rozen, R1
Chen, J; Dou, X; Li, S; Qian, Y; Song, Z; Xia, Y; Zhang, X1
Jinzenji, A; Kitayama, S; Miyawaki, T; Morita, K; Ohyama, K; Sogawa, C; Sogawa, N; Wen, XF; Yi, D1
French, BA; French, SW; Gong, M; Li, J; Liu, H; Tillman, B1
Kim, CJ; Kim, YG; Lee, SH; Lim, HH; Shin, MS; Yang, HJ1
Cai, W; Guo, Y; Huang, H; Lu, T; Tang, Q; Wu, Y; Zhu, J1
Benoist, JF; Blom, HJ; de Baulny, HO; de Vriese, AS; Esse, R; Gupta, S; Imbard, A; Kruger, W; Lebon, S; Schiff, M1
Gupta, S; Kruger, WD; Wang, L1
Hu, C; Huang, X; Lin, X; Niu, J; Tan, Y; Wang, H; Wang, X; Yin, P; Zeng, J; Zhou, L1
Nie, C; Nie, H; Wu, J; Zhang, X; Zhao, Y1
Gupta, S; Kruger, WD1
Burukoglu, D; Kanbak, G; Kusat Ol, K; Oğlakcı Ilhan, A; Yücel, F1
Badawi, A; Kandil, E; Mostafa, N; Noaman, E; Salem, A1
Bonitatibus, PJ; Butts, MD; Colborn, RE; FitzGerald, PF; Lee, BD; Roberts, JC; Torres, AS; Yeh, BM1
Koeberl, DD1
Jun, HO; Kang, BC; Kim, JH; Kwon, E; Park, SW; Park, YJ; Yun, JW1
Aykaç, A; Çetinel, Ş; Satılmış, B; Şehirli, AÖ; Şener, G; Tetik, Ş; Yeğen, B1
Kanbak, G; Kartkaya, K; Oglakci, A; Sogut, I; Uysal, O; Yucel, F1
Davis, SC; Gil, J; Harding, A; Higa, A; Parajon, F; Solis, M; Valdes, J1
DU, YP; Fan, RX; Hou, MJ; Lü, SW; Zhu, HL1
Du, Y; Fan, R; Hou, M; Ling, W; Lv, S; Tang, Z; Zhu, H1
Choi, HK; Kim, HS; Kim, SH; Kim, Y; Park, T; Yang, SO1
Gong, ZJ; Shi, QZ; Wang, LW; Zhang, W1
Bjorge, D; Schwan, WR; Wetzel, KJ1
Campion, J; Cordero, P; Martínez, JA; Milagro, FI1
Chaba, T; Jacobs, RL; Niebergall, LJ; Vance, DE1
Allen, RH; Greiner, LS; Jiang, H; Maclean, KN; Stabler, SP1
Detweiler, CS; Jorgensen, DR; Nagy, TA; Pilonieta, MC1
Allen, RH; Jiang, H; Maclean, KN; Stabler, SP1
Devaraj, S; Engelberg, JA; Halsted, CH; Havel, PJ; Jiang, JX; Kharbanda, KK; Kim, K; LaSalle, JM; Liu, S; Lönnerdal, B; Medici, V; Shibata, NM; Török, NJ; Woods, R1
Chai, GS; Cheng, XS; Jiang, X; Liu, GP; Ma, ZW; Ni, ZF; Wang, JZ; Wang, Q; Xie, AJ1
Aritsuka, T; Fukushima, M; Han, KH; Kawakami, S; Kitano, T; Nagura, T; Nakamura, K; Nakamura, Y; Ohba, K; Shimada, K1
Billington, CJ; Georgieff, MK; Gopalakrishnan, R; Hodges, JS; Petryk, A; Schmidt, B; Schotta, G; Zhang, L1
Ji, C; Kaplowitz, N1
Francis, GA; Gahan, CG; Hill, C; O'Beirne, D; Sleator, RD1
Chen, Z; Garrow, T; James, SJ; Laryea, MD; Melnyk, S; Pogribny, I; Rozen, R; Schwahn, BC1
Nakata, R; Okawa, N; Shigematsu, N; Yagisawa, M1
Barak, AJ; Beckenhauer, HC; Kharbanda, KK; Mailliard, ME; Rogers, DD; Siford, GL; Sorrell, MF; Tuma, DJ1
Balkus, JE; Hillier, SL; Patton, DL; Sweeney, YT1
Chambers, S; Fraser, R; George, P; Lever, M; McEntyre, C; Slow, S; Vasudevamurthy, M1
Abdelmalek, MF; Barve, S; Benevenga, NJ; Halsted, CH; Kaplowitz, N; Kharbanda, KK; Liu, QY; Lu, SC; McClain, CJ; Purohit, V; Swanson, C; Zakhari, S1
Cohn, J; Jiang, H; Maclean, KN; Mikael, LG; Rozen, R; Schwahn, BC; Wang, XL; Wu, Q1
Chen, T; Deaciuc, I; Hill, D; McClain, CJ; Song, M; Song, Z; Zhou, Z1
Chen, T; Deaciuc, I; McClain, CJ; Song, Z; Zhou, Z1
Cassuto, J; Gustafsson, T; Jönsson, A; Lindblom, L; Tarnow, P1
Bankovic-Calic, N; Buist, R; Nitschmann, E; Ogborn, MR; Peeling, J1
Barrell, GK; Chambers, ST; Dellow, WJ; Lever, M; Robson, RA1
Hashimoto, N; Hayakawa, JI; Higashi, Y; Miyamoto, KI; Nomura, M; Takeuchi, N; Tamai, I; Tsuji, A; Yokogawa, K1
Bloom, BR; Wiśniewski, HM1
Hülsmann, WC; Schneijdenberg, CT; Verkleij, AJ1
Fal', EA; Kadan, LP; Kruglova, IF; Shatrov, VA1

Reviews

3 review(s) available for betaine and Disease Models, Animal

ArticleYear
The metabolic burden of methyl donor deficiency with focus on the betaine homocysteine methyltransferase pathway.
    Nutrients, 2013, Sep-09, Volume: 5, Issue:9

    Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Dietary Supplements; Disease Models, Animal; DNA Methylation; Fasting; Fatty Liver; Folic Acid; Homocysteine; Humans; Liver; Metabolic Networks and Pathways; Methionine; Muscular Diseases; S-Adenosylmethionine

2013
The effect of dietary modulation of sulfur amino acids on cystathionine β synthase-deficient mice.
    Annals of the New York Academy of Sciences, 2016, Volume: 1363

    Topics: Acetylcysteine; Amino Acids, Sulfur; Animals; Betaine; Cystathionine beta-Synthase; Diet; Dietary Supplements; Disease Models, Animal; Genotype; Homocystinuria; Humans; Metabolic Networks and Pathways; Methionine; Mice; Mice, Knockout; Mutation; Phenotype

2016
Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: summary of a symposium.
    The American journal of clinical nutrition, 2007, Volume: 86, Issue:1

    Topics: Animals; Betaine; Disease Models, Animal; Folic Acid; Humans; Liver Diseases, Alcoholic; Methionine; S-Adenosylmethionine

2007

Other Studies

84 other study(ies) available for betaine and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries

2019
Betaine prevents and reverses the behavioral deficits and synaptic dysfunction induced by repeated ketamine exposure in mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 144

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Betaine; Cognition; Disease Models, Animal; Disks Large Homolog 4 Protein; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Hippocampus; Ketamine; Locomotion; Male; Mice, Inbred ICR; Neuronal Plasticity; Open Field Test; Psychoses, Substance-Induced; Recognition, Psychology; Social Behavior; Swimming; Synaptic Transmission

2021
Preventive Effect of Betaine Against Cognitive Impairments in Amyloid β Peptide-Injected Mice Through Sirtuin1 in Hippocampus.
    Neurochemical research, 2022, Volume: 47, Issue:8

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Betaine; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Maze Learning; Memory Disorders; Mice; Peptide Fragments; Sirtuin 1

2022
Betaine Ameliorates Acute Sever Ulcerative Colitis by Inhibiting Oxidative Stress Induced Inflammatory Pyroptosis.
    Molecular nutrition & food research, 2022, Volume: 66, Issue:22

    Topics: Animals; Betaine; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Pyroptosis

2022
Betaine supplementation alleviates dextran sulfate sodium-induced colitis
    Food & function, 2022, Dec-13, Volume: 13, Issue:24

    Topics: Animals; Anti-Inflammatory Agents; Betaine; Caco-2 Cells; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Humans; Inflammatory Bowel Diseases; Mice; Mice, Inbred C57BL

2022
Methyl donor supplementation reduces phospho-Tau, Fyn and demethylated protein phosphatase 2A levels and mitigates learning and motor deficits in a mouse model of tauopathy.
    Neuropathology and applied neurobiology, 2023, Volume: 49, Issue:4

    Topics: Alzheimer Disease; Animals; Betaine; Carbon; Choline; Dietary Supplements; Disease Models, Animal; Folic Acid; Humans; Mice; Mice, Transgenic; Phosphorylation; Protein Phosphatase 2; tau Proteins; Tauopathies

2023
Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathways.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 120

    Topics: Animals; Antioxidants; Betaine; Blood-Testis Barrier; Catalase; Diabetes Mellitus, Experimental; Disease Models, Animal; Glutathione; Lycium; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Protective Agents; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Testis

2019
Effect of Betaine Supplementation on Liver Tissue and Ultrastructural Changes in Methionine-Choline-Deficient Diet-Induced NAFLD.
    Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada, 2020, Volume: 26, Issue:5

    Topics: Animals; Betaine; Choline; Collagen; Diet; Dietary Supplements; Disease Models, Animal; Hepatocytes; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease

2020
Betaine effects against asthma-induced oxidative stress in the liver and kidney of mice.
    Molecular biology reports, 2020, Volume: 47, Issue:8

    Topics: Animals; Antioxidants; Asthma; Betaine; Disease Models, Animal; Female; Glucocorticoids; Inflammation; Kidney Diseases; Lipotropic Agents; Liver Diseases; Mice; Mice, Inbred BALB C; Oxidative Stress; Prednisolone

2020
Hyperhomocysteinemia and dyslipidemia in point mutation G307S of cystathionine β-synthase-deficient rabbit generated using CRISPR/Cas9.
    Lipids in health and disease, 2020, Oct-14, Volume: 19, Issue:1

    Topics: Animals; Betaine; Body Weight; CRISPR-Cas Systems; Cystathionine beta-Synthase; Disease Models, Animal; Dyslipidemias; Female; Gene Knockout Techniques; Hyperhomocysteinemia; Hyperlipidemias; Liver; Male; Point Mutation; Rabbits; Vitamin B Complex

2020
Betaine inhibits Toll-like receptor 4 responses and restores intestinal microbiota in acute liver failure mice.
    Scientific reports, 2020, 12-14, Volume: 10, Issue:1

    Topics: Animals; Bacteria; Betaine; Cell Line; Disease Models, Animal; Gastrointestinal Microbiome; Intestine, Small; Liver Failure, Acute; Male; Mice; Rats; Toll-Like Receptor 4

2020
Preventive Effects of Continuous Betaine Intake on Cognitive Impairment and Aberrant Gene Expression in Hippocampus of 3xTg Mouse Model of Alzheimer's Disease.
    Journal of Alzheimer's disease : JAD, 2021, Volume: 79, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Betaine; Cognition; Cognitive Dysfunction; Disease Models, Animal; Gastrointestinal Agents; Gene Expression; Hippocampus; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; Synapses

2021
Derangement of hepatic polyamine, folate, and methionine cycle metabolism in cystathionine beta-synthase-deficient homocystinuria in the presence and absence of treatment: Possible implications for pathogenesis.
    Molecular genetics and metabolism, 2021, Volume: 132, Issue:2

    Topics: Adenosylhomocysteinase; Animals; Betaine; Cystathionine beta-Synthase; Disease Models, Animal; Folic Acid; Gene Expression Regulation, Enzymologic; Glycine Hydroxymethyltransferase; Homocysteine; Homocystinuria; Humans; Liver; Methionine; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Polyamines

2021
Betaine ameliorates schizophrenic traits by functionally compensating for KIF3-based CRMP2 transport.
    Cell reports, 2021, 04-13, Volume: 35, Issue:2

    Topics: Actins; Animals; Behavior, Animal; Betaine; Biological Transport; Diet; Disease Models, Animal; Gene Expression Regulation, Developmental; Humans; Intercellular Signaling Peptides and Proteins; Kinesins; Male; Mice; Mice, Knockout; Microtubules; Nerve Tissue Proteins; Neurons; Prefrontal Cortex; Protein Binding; Protein Carbonylation; Pseudopodia; Schizophrenia

2021
Betaine alleviates right ventricular failure via regulation of Rho A/ROCK signaling pathway in rats with pulmonary arterial hypertension.
    European journal of pharmacology, 2021, Nov-05, Volume: 910

    Topics: Actins; Administration, Oral; Animals; Apoptosis; Arterioles; Betaine; Cardiotonic Agents; Disease Models, Animal; Electrocardiography; Heart Failure; Heart Ventricles; Male; Monocrotaline; Proliferating Cell Nuclear Antigen; Pulmonary Arterial Hypertension; Pulmonary Artery; Rats, Sprague-Dawley; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Vascular Remodeling

2021
Translatome analysis reveals the regulatory role of betaine in high fat diet (HFD)-induced hepatic steatosis.
    Biochemical and biophysical research communications, 2021, 10-20, Volume: 575

    Topics: Animals; Betaine; Diet, High-Fat; Disease Models, Animal; Gene Expression Profiling; Lipid Metabolism; Lipotropic Agents; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Protein Biosynthesis; Random Allocation; Sequence Analysis, RNA; Transcriptome

2021
Effects of Lycium barbarum (goji berry) on dry eye disease in rats.
    Molecular medicine reports, 2018, Volume: 17, Issue:1

    Topics: Animals; Betaine; Disease Models, Animal; Dry Eye Syndromes; Kidney; Liver; Lycium; Male; Plant Extracts; Plants, Medicinal; Polysaccharides; Rats

2018
The Effects of Betaine on the Nuclear Fractal Dimension, Chromatin Texture, and Proliferative Activity in Hepatocytes in Mouse Model of Nonalcoholic Fatty Liver Disease.
    Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada, 2018, Volume: 24, Issue:2

    Topics: Animals; Betaine; Cell Nucleus; Cell Proliferation; Chromatin; Disease Models, Animal; Gastrointestinal Agents; Hepatocytes; Histocytochemistry; Immunohistochemistry; Ki-67 Antigen; Liver; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease

2018
Corticosterone-Induced Lipogenesis Activation and Lipophagy Inhibition in Chicken Liver Are Alleviated by Maternal Betaine Supplementation.
    The Journal of nutrition, 2018, 03-01, Volume: 148, Issue:3

    Topics: Animals; Betaine; Chickens; Corticosterone; Dietary Supplements; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Fatty Liver; Female; Lipid Metabolism; Lipogenesis; Liver; Male; Mitochondria; Mitochondrial Proteins; Pregnancy; Prenatal Nutritional Physiological Phenomena; Promoter Regions, Genetic; Receptors, Glucocorticoid; Triglycerides

2018
Chlorhexidine-releasing implant coating on intramedullary nail reduces infection in a rat model.
    European cells & materials, 2018, 03-22, Volume: 35

    Topics: Animals; Anti-Bacterial Agents; Betaine; Bone and Bones; Bone Nails; Cefazolin; Chlorhexidine; Coated Materials, Biocompatible; Communicable Diseases; Disease Models, Animal; Drug Liberation; Fracture Fixation, Intramedullary; Fracture Healing; Rats; Titanium

2018
Betaine treatment protects liver through regulating mitochondrial function and counteracting oxidative stress in acute and chronic animal models of hepatic injury.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 103

    Topics: Acute Disease; Animals; Betaine; Bile Ducts; Biomarkers; Chronic Disease; Disease Models, Animal; Ligation; Liver; Male; Mitochondria; Oxidative Stress; Protective Agents; Rats, Sprague-Dawley

2018
Betaine Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats via Inhibiting Inflammatory Response.
    Molecules (Basel, Switzerland), 2018, May-26, Volume: 23, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Betaine; Biomarkers; Chemokine CCL2; Cytokines; Disease Models, Animal; Endothelin-1; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Immunohistochemistry; Inflammation Mediators; Male; Monocrotaline; Myocardium; NF-kappa B; Pulmonary Artery; Rats

2018
Maternal Choline and Betaine Supplementation Modifies the Placental Response to Hyperglycemia in Mice and Human Trophoblasts.
    Nutrients, 2018, Oct-15, Volume: 10, Issue:10

    Topics: Animal Feed; Animals; Betaine; Biomarkers; Blood Glucose; Cell Line, Tumor; Choline; Diabetes, Gestational; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Energy Metabolism; Female; Gene Expression Regulation; Humans; Maternal-Fetal Exchange; Mice, Inbred C57BL; Neovascularization, Physiologic; Placenta; Pregnancy; Trophoblasts

2018
Sheathless CE-MS based metabolic profiling of kidney tissue section samples from a mouse model of Polycystic Kidney Disease.
    Scientific reports, 2019, 01-28, Volume: 9, Issue:1

    Topics: Animals; Betaine; Carnitine; Creatine; Creatinine; Disease Models, Animal; Electrophoresis, Capillary; Glutamine; Kidney; Mass Spectrometry; Metabolomics; Mice; Multivariate Analysis; Polycystic Kidney Diseases

2019
Taurine alleviates repression of betaine-homocysteine
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:5

    Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Disease Models, Animal; Homocystinuria; Humans; Liver; Mice; Mice, Knockout; Taurine

2019
Betaine ameliorates prenatal valproic-acid-induced autism-like behavioral abnormalities in mice by promoting homocysteine metabolism.
    Psychiatry and clinical neurosciences, 2019, Volume: 73, Issue:6

    Topics: Animals; Antimanic Agents; Autism Spectrum Disorder; Behavior, Animal; Betaine; Disease Models, Animal; Female; Homocysteine; Mice; Mice, Inbred ICR; Pregnancy; Prenatal Exposure Delayed Effects; Protective Agents; Social Behavior; Valproic Acid

2019
Metabolomic analyses reveal lipid abnormalities and hepatic dysfunction in non-human primate model for Yersinia pestis.
    Metabolomics : Official journal of the Metabolomic Society, 2018, 12-29, Volume: 15, Issue:1

    Topics: Animals; Betaine; Carnitine; Chlorocebus aethiops; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Metabolomics; Yersinia pestis

2018
Betaine-rich sugar beet molasses protects from homocysteine-induced reduction of survival in Caenorhabditis elegans.
    European journal of nutrition, 2020, Volume: 59, Issue:2

    Topics: Animals; Betaine; Caenorhabditis elegans; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Homocysteine; Hot Temperature; Molasses; Stress, Physiological; Survival Analysis

2020
Investigation of betaine as a novel psychotherapeutic for schizophrenia.
    EBioMedicine, 2019, Volume: 45

    Topics: Animals; Betaine; Brain; Choline Dehydrogenase; Dietary Supplements; Disease Models, Animal; DNA Methylation; Genotype; Humans; Japan; Liver; Male; Methamphetamine; Mice; Oxidative Stress; Psychotropic Drugs; Quantitative Trait Loci; Schizophrenia

2019
Premature impairment of methylation pathway and cardiac metabolic dysfunction in fa/fa obese Zucker rats.
    Journal of proteome research, 2013, Apr-05, Volume: 12, Issue:4

    Topics: Adipose Tissue, White; Age Factors; Animals; Betaine; Disease Models, Animal; Inositol; Liver; Magnetic Resonance Spectroscopy; Male; Metabolomics; Methylation; Myocardium; Obesity; Phosphorylcholine; Rats; Rats, Zucker

2013
Diet influences expression of autoimmune-associated genes and disease severity by epigenetic mechanisms in a transgenic mouse model of lupus.
    Arthritis and rheumatism, 2013, Volume: 65, Issue:7

    Topics: Animals; Antibodies, Antinuclear; Betaine; CD40 Ligand; Choline; Coenzymes; Diet; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Folic Acid; Gene Silencing; Genetic Predisposition to Disease; Lupus Erythematosus, Systemic; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Micronutrients; Riboflavin; Vitamin B 12; Vitamin B 6; Zinc

2013
Surface zwitterionization of expanded poly(tetrafluoroethylene) membranes via atmospheric plasma-induced polymerization for enhanced skin wound healing.
    ACS applied materials & interfaces, 2013, Jul-24, Volume: 5, Issue:14

    Topics: Adsorption; Animals; Bacterial Adhesion; Betaine; Biocompatible Materials; Blood Proteins; Cell Line, Tumor; Disease Models, Animal; Escherichia coli; Fluorocarbons; Humans; Membranes, Artificial; Methacrylates; Polyethylene Glycols; Polymerization; Polymers; Rats; Rats, Sprague-Dawley; Skin; Staphylococcus epidermidis; Surface Properties; Wound Healing

2013
The antimicrobial agent C31G is effective for therapy for HSV-1 ocular keratitis in the rabbit eye model.
    Antiviral research, 2013, Volume: 100, Issue:1

    Topics: Animals; Antiviral Agents; Betaine; Cornea; Disease Models, Animal; Fatty Acids, Unsaturated; Herpesvirus 1, Human; Humans; Keratitis, Herpetic; Rabbits

2013
Efficacy of osmoprotectants on prevention and treatment of murine dry eye.
    Investigative ophthalmology & visual science, 2013, Sep-19, Volume: 54, Issue:9

    Topics: Animals; Apoptosis; Betaine; Carnitine; Cornea; Disease Models, Animal; Disease Progression; Dry Eye Syndromes; Erythritol; Female; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Ophthalmic Solutions; Water-Electrolyte Balance

2013
Betaine reduces serum uric acid levels and improves kidney function in hyperuricemic mice.
    Planta medica, 2014, Volume: 80, Issue:1

    Topics: Acetylglucosaminidase; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; beta 2-Microglobulin; Betaine; Blood Urea Nitrogen; Carrier Proteins; Creatinine; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose Transport Proteins, Facilitative; Hyperuricemia; Kidney; Male; Membrane Proteins; Mice; Octamer Transcription Factor-1; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Cation Transport Proteins; Solute Carrier Family 22 Member 5; Symporters; Uric Acid

2014
Mouse model for deficiency of methionine synthase reductase exhibits short-term memory impairment and disturbances in brain choline metabolism.
    The Biochemical journal, 2014, Jul-15, Volume: 461, Issue:2

    Topics: Acetylcholinesterase; Animals; Apoptosis; Betaine; Cerebellum; Choline; Choline O-Acetyltransferase; Disease Models, Animal; DNA Methylation; Ferredoxin-NADP Reductase; Gene Expression; Hippocampus; Homocysteine; Homocystinuria; Hyperhomocysteinemia; Male; Memory, Short-Term; Methionine; Mice; Mice, Knockout; Synaptic Transmission

2014
Rectification of impaired adipose tissue methylation status and lipolytic response contributes to hepatoprotective effect of betaine in a mouse model of alcoholic liver disease.
    British journal of pharmacology, 2014, Volume: 171, Issue:17

    Topics: 3T3-L1 Cells; Adipose Tissue; Animals; Betaine; Cells, Cultured; Cytoprotection; Disease Models, Animal; Hep G2 Cells; Humans; Lipolysis; Liver Diseases, Alcoholic; Male; Methylation; Mice; Mice, Inbred C57BL

2014
Antiallodynic action of 1-(3-(9H-Carbazol-9-yl)-1-propyl)-4-(2-methyoxyphenyl)-4-piperidinol (NNC05-2090), a betaine/GABA transporter inhibitor.
    Journal of pharmacological sciences, 2014, Volume: 125, Issue:2

    Topics: Animals; Betaine; CHO Cells; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Male; Mice, Inbred Strains; Neuralgia; Piperidines

2014
Mallory-Denk Body (MDB) formation modulates Ufmylation expression epigenetically in alcoholic hepatitis (AH) and non-alcoholic steatohepatitis (NASH).
    Experimental and molecular pathology, 2014, Volume: 97, Issue:3

    Topics: Animals; Betaine; Blotting, Western; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Hepatitis, Alcoholic; Humans; Male; Mallory Bodies; Mice; Non-alcoholic Fatty Liver Disease; Proteins; Real-Time Polymerase Chain Reaction; Signal Transduction

2014
Betaine inhibits vascularization via suppression of Akt in the retinas of streptozotocin-induced hyperglycemic rats.
    Molecular medicine reports, 2015, Volume: 12, Issue:2

    Topics: Animals; Betaine; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Lycium; Male; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Retina; Retinal Neovascularization; Signal Transduction; Streptozocin; Vascular Endothelial Growth Factor A

2015
Choline Alleviates Parenteral Nutrition-Associated Duodenal Motility Disorder in Infant Rats.
    JPEN. Journal of parenteral and enteral nutrition, 2016, Volume: 40, Issue:7

    Topics: Animals; Animals, Newborn; Betaine; Choline; Disease Models, Animal; Duodenum; Gastrointestinal Motility; Intestinal Diseases; Male; Oxidative Stress; Parenteral Nutrition; Phosphorylcholine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Tumor Necrosis Factor-alpha

2016
High homocysteine induces betaine depletion.
    Bioscience reports, 2015, Apr-28, Volume: 35, Issue:4

    Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Carrier Proteins; Disease Models, Animal; Female; GABA Plasma Membrane Transport Proteins; Homocysteine; Homocystinuria; Humans; Male; Mice; Mice, Transgenic; Rats; Rats, Wistar

2015
Betaine supplementation is less effective than methionine restriction in correcting phenotypes of CBS deficient mice.
    Journal of inherited metabolic disease, 2016, Volume: 39, Issue:1

    Topics: Animals; Betaine; Bone Density; Cystathionine beta-Synthase; Diet; Dietary Supplements; Disease Models, Animal; Female; Homocystinuria; Male; Methionine; Mice; Mice, Inbred C57BL; Osteoporosis; Phenotype; Weight Gain; Weight Loss

2016
Metabolomics Identifies Biomarker Pattern for Early Diagnosis of Hepatocellular Carcinoma: from Diethylnitrosamine Treated Rats to Patients.
    Scientific reports, 2015, Nov-03, Volume: 5

    Topics: alpha-Fetoproteins; Animals; Betaine; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cohort Studies; Creatine; Diethylnitrosamine; Disease Models, Animal; Early Diagnosis; Female; Humans; Liver Neoplasms; Male; Metabolomics; Multivariate Analysis; Rats; Rats, Sprague-Dawley

2015
Betaine reverses the memory impairments in a chronic cerebral hypoperfusion rat model.
    Neuroscience letters, 2016, Feb-26, Volume: 615

    Topics: Animals; Betaine; Brain; Chronic Disease; Dementia, Vascular; Disease Models, Animal; Disks Large Homolog 4 Protein; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Memory Disorders; Microtubule-Associated Proteins; Oxidative Stress; Rats, Sprague-Dawley; Spatial Learning; Synapses

2016
The investigation of the prenatal and postnatal alcohol exposure-induced neurodegeneration in rat brain: protection by betaine and/or omega-3.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2016, Volume: 32, Issue:3

    Topics: Animals; Betaine; Brain; Central Nervous System Depressants; Disease Models, Animal; Ethanol; Fatty Acids, Omega-3; Female; Lipotropic Agents; Nerve Degeneration; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley

2016
Crystal structure and chemotherapeutic efficacy of the novel compound, gallium tetrachloride betaine, against breast cancer using nanotechnology.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:8

    Topics: Animals; Apoptosis; Betaine; Crystallography, X-Ray; Disease Models, Animal; Drug Carriers; Female; Gallium; Humans; Mammary Neoplasms, Experimental; MCF-7 Cells; Metal Nanoparticles; Nanotechnology; Oxidative Stress; Rats; Zinc Oxide

2016
A Proposed Computed Tomography Contrast Agent Using Carboxybetaine Zwitterionic Tantalum Oxide Nanoparticles: Imaging, Biological, and Physicochemical Performance.
    Investigative radiology, 2016, Volume: 51, Issue:12

    Topics: Acute Kidney Injury; Animals; Betaine; Contrast Media; Disease Models, Animal; Kidney; Male; Nanoparticles; Oxides; Phantoms, Imaging; Radiographic Image Enhancement; Rats; Tantalum; Tomography, X-Ray Computed

2016
Vision of correction for classic homocystinuria.
    The Journal of clinical investigation, 2016, 06-01, Volume: 126, Issue:6

    Topics: Animals; Betaine; Cystathionine beta-Synthase; Disease Models, Animal; Homocystinuria; Humans; Mice; Phenotype

2016
Antiangiogenic effect of betaine on pathologic retinal neovascularization via suppression of reactive oxygen species mediated vascular endothelial growth factor signaling.
    Vascular pharmacology, 2017, Volume: 90

    Topics: Angiogenesis Inhibitors; Animals; Animals, Newborn; Astrocytes; Betaine; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Humans; Hyperoxia; Intravitreal Injections; Mice, Inbred C57BL; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Retinal Neovascularization; Retinal Vessels; Retinopathy of Prematurity; Signal Transduction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2017
Protective effect of betaine against burn-induced pulmonary injury in rats.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2016, Volume: 22, Issue:5

    Topics: Administration, Oral; Animals; Antioxidants; Betaine; Burns; Cytokines; Disease Models, Animal; Female; Glutathione; L-Lactate Dehydrogenase; Lung Injury; Male; Malondialdehyde; Peroxidase; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase

2016
Prenatal alcohol-induced neuroapoptosis in rat brain cerebral cortex: protective effect of folic acid and betaine.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2017, Volume: 33, Issue:3

    Topics: Animals; Animals, Newborn; Apoptosis; Betaine; Blood Alcohol Content; Calpain; Caspase 3; Cathepsin B; Cathepsin L; Central Nervous System Depressants; Cerebral Cortex; Cytochromes c; Disease Models, Animal; Ethanol; Female; Folic Acid; Neuroprotective Agents; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley

2017
Effectiveness of a polyhexanide irrigation solution on methicillin-resistant Staphylococcus aureus biofilms in a porcine wound model.
    International wound journal, 2017, Volume: 14, Issue:6

    Topics: Animals; Betaine; Biguanides; Biofilms; Disease Models, Animal; Disinfectants; Methicillin-Resistant Staphylococcus aureus; Staphylococcal Infections; Swine; Wounds and Injuries

2017
[Anti-atherosclerotic effect of betaine in apolipoprotein E-deficient mice].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2008, Volume: 42, Issue:10

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Betaine; Chemokine CCL2; Dietary Supplements; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Tumor Necrosis Factor-alpha

2008
Betaine supplementation attenuates atherosclerotic lesion in apolipoprotein E-deficient mice.
    European journal of nutrition, 2009, Volume: 48, Issue:4

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Betaine; Chemokine CCL2; Dietary Supplements; Disease Models, Animal; DNA Methylation; Dose-Response Relationship, Drug; Inflammation Mediators; Linear Models; Lipids; Male; Mice; Mice, Inbred C57BL; Random Allocation; Tumor Necrosis Factor-alpha

2009
1H-nuclear magnetic resonance spectroscopy-based metabolic assessment in a rat model of obesity induced by a high-fat diet.
    Analytical and bioanalytical chemistry, 2009, Volume: 395, Issue:4

    Topics: Acetoacetates; Acetone; Animals; Betaine; Citric Acid; Dietary Fats; Disease Models, Animal; Glycine; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Multivariate Analysis; Obesity; Protons; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Taurine

2009
Betaine inhibits toll-like receptor 4 expression in rats with ethanol-induced liver injury.
    World journal of gastroenterology, 2010, Feb-21, Volume: 16, Issue:7

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Betaine; Biomarkers; Blotting, Western; Body Weight; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Endotoxins; Ethanol; Female; Interferon-gamma; Interleukin-18; Liver; Liver Diseases, Alcoholic; Organ Size; Protective Agents; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha

2010
Mutational and transcriptional analyses of the Staphylococcus aureus low-affinity proline transporter OpuD during in vitro growth and infection of murine tissues.
    FEMS immunology and medical microbiology, 2011, Volume: 61, Issue:3

    Topics: Amino Acid Transport Systems, Neutral; Animals; Betaine; Disease Models, Animal; DNA Mutational Analysis; Gene Expression Profiling; Mice; Mutant Proteins; Mutation, Missense; Proline; Rodent Diseases; Staphylococcal Infections; Staphylococcus aureus; Transcription, Genetic; Urinary Tract; Urinary Tract Infections

2011
Dietary supplementation with methyl donor groups could prevent nonalcoholic fatty liver.
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:6

    Topics: Animals; Betaine; Choline; Dietary Fats; Dietary Sucrose; Dietary Supplements; Disease Models, Animal; Fatty Liver; Folic Acid; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar; Vitamin B 12

2011
Phosphatidylcholine protects against steatosis in mice but not non-alcoholic steatohepatitis.
    Biochimica et biophysica acta, 2011, Volume: 1811, Issue:12

    Topics: Adenoviridae; Animals; Betaine; Ceramides; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Female; Genetic Predisposition to Disease; Genetic Vectors; Lipotropic Agents; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Triglycerides

2011
Long-term betaine therapy in a murine model of cystathionine beta-synthase deficient homocystinuria: decreased efficacy over time reveals a significant threshold effect between elevated homocysteine and thrombotic risk.
    Molecular genetics and metabolism, 2012, Volume: 105, Issue:3

    Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Blood Coagulation; Cystathionine beta-Synthase; Diet; Dietary Supplements; Disease Models, Animal; Homocysteine; Homocystinuria; Interleukin-1beta; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Thrombosis; Tumor Necrosis Factor-alpha

2012
A glycine betaine importer limits Salmonella stress resistance and tissue colonization by reducing trehalose production.
    Molecular microbiology, 2012, Volume: 84, Issue:2

    Topics: Animals; Betaine; Disease Models, Animal; Gene Deletion; Hydrogen Peroxide; Hydrogen-Ion Concentration; Macrophages; Membrane Transport Proteins; Mice; Salinity; Salmonella Infections, Animal; Salmonella typhimurium; Salts; Stress, Physiological; Trehalose

2012
Altered expression of apoA-I, apoA-IV and PON-1 activity in CBS deficient homocystinuria in the presence and absence of treatment: possible implications for cardiovascular outcomes.
    Molecular genetics and metabolism, 2012, Volume: 107, Issue:1-2

    Topics: Adolescent; Adult; Animals; Apolipoprotein A-I; Apolipoproteins A; Aryldialkylphosphatase; Betaine; Brain; Carboxylic Ester Hydrolases; Child; Child, Preschool; Dietary Supplements; Disease Models, Animal; Homocysteine; Homocystinuria; Humans; Lipotropic Agents; Liver; Male; Mice; Mice, Knockout; Young Adult

2012
Wilson's disease: changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease.
    Hepatology (Baltimore, Md.), 2013, Volume: 57, Issue:2

    Topics: Adenosylhomocysteinase; Animals; Betaine; Copper; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Down-Regulation; Endoplasmic Reticulum Stress; Epigenesis, Genetic; Hepatolenticular Degeneration; Inflammation; Liver; Methionine; Mice; Mice, Inbred C3H; Penicillamine; S-Adenosylhomocysteine

2013
Betaine attenuates Alzheimer-like pathological changes and memory deficits induced by homocysteine.
    Journal of neurochemistry, 2013, Volume: 124, Issue:3

    Topics: Alzheimer Disease; Animals; Betaine; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Lipotropic Agents; Male; Memory Disorders; Rats; Rats, Sprague-Dawley

2013
Effects of dietary supplementation with betaine on a nonalcoholic steatohepatitis (NASH) mouse model.
    Journal of nutritional science and vitaminology, 2012, Volume: 58, Issue:5

    Topics: Alanine Transaminase; Animals; Betaine; Body Weight; Diet, High-Fat; Dietary Fats; Dietary Supplements; Disease Models, Animal; Fatty Liver; Glutamyl Aminopeptidase; Glutathione; Hepatocytes; Liver; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Organ Size; Triglycerides

2012
Maternal diet supplementation with methyl donors and increased parity affect the incidence of craniofacial defects in the offspring of twisted gastrulation mutant mice.
    The Journal of nutrition, 2013, Volume: 143, Issue:3

    Topics: Animals; Betaine; Choline; Craniofacial Abnormalities; Dietary Supplements; Disease Models, Animal; Face; Female; Folic Acid; Gastrulation; Jaw; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Parity; Pregnancy; Proteins; Risk Factors; Vitamin B 12; Vitamin B Complex

2013
Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice.
    Gastroenterology, 2003, Volume: 124, Issue:5

    Topics: Animals; Betaine; Central Nervous System Depressants; Disease Models, Animal; Endoplasmic Reticulum; Ethanol; Fatty Liver, Alcoholic; Gastrointestinal Agents; Gene Expression; Homocysteine; Hyperhomocysteinemia; Liver; Male; Methionine; Methylation; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis

2003
Betaine and carnitine uptake systems in Listeria monocytogenes affect growth and survival in foods and during infection.
    Journal of applied microbiology, 2003, Volume: 95, Issue:4

    Topics: Animals; Betaine; Carnitine; Cryoprotective Agents; Disease Models, Animal; Food Microbiology; Humans; Listeria monocytogenes; Listeriosis; Meat Products; Mice; Mice, Inbred BALB C; Mutation; Risk Factors; Vegetables; Virulence

2003
Betaine rescue of an animal model with methylenetetrahydrofolate reductase deficiency.
    The Biochemical journal, 2004, Sep-15, Volume: 382, Issue:Pt 3

    Topics: Animals; Animals, Suckling; Betaine; Body Weight; Brain; Disease Models, Animal; Female; Genotype; Homocysteine; Homocystinuria; Lactation; Liver; Male; Maternal-Fetal Exchange; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Knockout; Organ Size; Pregnancy

2004
Effects of intravenous betaine on methionine-loading-induced plasma homocysteine elevation in rats.
    The Journal of nutritional biochemistry, 2004, Volume: 15, Issue:11

    Topics: Animals; Betaine; Disease Models, Animal; Glycine; Homocysteine; Hyperhomocysteinemia; Injections, Intravenous; Male; Methionine; Rats; Sarcosine

2004
A comparison of the effects of betaine and S-adenosylmethionine on ethanol-induced changes in methionine metabolism and steatosis in rat hepatocytes.
    The Journal of nutrition, 2005, Volume: 135, Issue:3

    Topics: Animals; Betaine; Disease Models, Animal; Ethanol; Fatty Liver; Hepatocytes; Male; Methionine; Methyltransferases; Microsomes, Liver; Phosphatidylethanolamine N-Methyltransferase; Rats; Rats, Wistar; S-Adenosylmethionine

2005
Vaginal and rectal topical microbicide development: safety and efficacy of 1.0% Savvy (C31G) in the pigtailed macaque.
    Sexually transmitted diseases, 2006, Volume: 33, Issue:11

    Topics: Administration, Intravaginal; Administration, Rectal; Animals; Anti-Infective Agents, Local; Betaine; Cervix Uteri; Chlamydia Infections; Chlamydia trachomatis; Disease Models, Animal; Fatty Acids, Unsaturated; Female; Macaca nemestrina; Rectum; Sexually Transmitted Diseases; Vagina

2006
Dimethylthetin treatment causes diffuse alveolar lung damage: a pilot study in a sheep model of Continuous Ambulatory Peritoneal Dialysis (CAPD).
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2007, Volume: 58, Issue:5

    Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Dialysis Solutions; Disease Models, Animal; Glycine; Homocysteine; Hyperhomocysteinemia; Nephrectomy; Peritoneal Dialysis, Continuous Ambulatory; Pilot Projects; Pulmonary Alveoli; Renal Insufficiency; Sheep; Substrate Specificity

2007
Betaine supplementation improves the atherogenic risk factor profile in a transgenic mouse model of hyperhomocysteinemia.
    Atherosclerosis, 2007, Volume: 195, Issue:2

    Topics: Animals; Animals, Genetically Modified; Aorta; Apolipoprotein A-I; Betaine; Cholesterol; Disease Models, Animal; Fatty Liver; Homocysteine; Hyperhomocysteinemia; Immunohistochemistry; Lipotropic Agents; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Time; Triglycerides; Tyrosine

2007
Involvement of AMP-activated protein kinase in beneficial effects of betaine on high-sucrose diet-induced hepatic steatosis.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 293, Issue:4

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Animals; Betaine; Cell Line; Dietary Carbohydrates; Disease Models, Animal; Fatty Liver; Humans; Male; Mice; Mice, Inbred C57BL; Multienzyme Complexes; Protein Serine-Threonine Kinases; Sucrose

2007
Inhibition of adiponectin production by homocysteine: a potential mechanism for alcoholic liver disease.
    Hepatology (Baltimore, Md.), 2008, Volume: 47, Issue:3

    Topics: Adiponectin; Adipose Tissue; Animals; Betaine; Cystathionine beta-Synthase; Disease Models, Animal; Endoplasmic Reticulum; Ethanol; Homocysteine; Hyperhomocysteinemia; Liver Diseases, Alcoholic; Male; Methionine; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Rats; Rats, Sprague-Dawley

2008
Topical D-myo-inositol-1,2,6-trisphosphate and hexylbetaine treatment reduces albumin extravasation in experimental rat skin burn injury.
    Burns : journal of the International Society for Burn Injuries, 1998, Volume: 24, Issue:5

    Topics: Administration, Topical; Albumins; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Betaine; Burns; Confidence Intervals; Disease Models, Animal; Evans Blue; Inositol Phosphates; Male; Occlusive Dressings; Rats; Rats, Sprague-Dawley; Reference Values; Skin; Spectrophotometry

1998
Dietary betaine modifies hepatic metabolism but not renal injury in rat polycystic kidney disease.
    American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 279, Issue:6

    Topics: Animals; Betaine; Diet; Dietary Supplements; Disease Models, Animal; Kidney; Liver; Magnetic Resonance Spectroscopy; Polycystic Kidney Diseases; Rats; Rats, Mutant Strains

2000
Glycine betaine excretion is not directly linked to plasma glucose concentrations in hyperglycaemia.
    Diabetes research and clinical practice, 2001, Volume: 52, Issue:3

    Topics: Animals; Betaine; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Glycosuria; Humans; Hyperglycemia; Sheep; Statistics, Nonparametric; Time Factors

2001
Effect of gamma-butyrobetaine on fatty liver in juvenile visceral steatosis mice.
    The Journal of pharmacy and pharmacology, 2001, Volume: 53, Issue:4

    Topics: Animals; Betaine; Carnitine; Carrier Proteins; Disease Models, Animal; Fatty Acids; Infusions, Intravenous; Liver; Mice; Organic Cation Transport Proteins; Solute Carrier Family 22 Member 5

2001
Experimental allergic optic neuritis (EAON) in the rabbit. A new model to study primary demyelinating diseases.
    Journal of the neurological sciences, 1975, Volume: 24, Issue:2

    Topics: Animals; Antigens; Betaine; Demyelinating Diseases; Disease Models, Animal; Epitopes; Freund's Adjuvant; Immunity, Cellular; Immunization; Nerve Fibers, Myelinated; Optic Nerve; Optic Neuritis; Rabbits; Tuberculin

1975
Accumulation and excretion of long-chain acylcarnitine by rat hearts; studies with aminocarnitine.
    Biochimica et biophysica acta, 1991, Nov-21, Volume: 1097, Issue:4

    Topics: Animals; Betaine; Carnitine; Carnitine O-Palmitoyltransferase; Coronary Disease; Disease Models, Animal; Heart; Microscopy, Electron; Mitochondria, Heart; Myocardium; Perfusion; Rats; Rats, Inbred Strains; Sarcolemma

1991
[Immunostimulating effect of synthetic surface-active agents in experimental tuberculosis].
    Problemy tuberkuleza, 1990, Issue:10

    Topics: Adjuvants, Immunologic; Animals; Betaine; Cyclic N-Oxides; Detergents; Disease Models, Animal; Macrophages; Mice; Mice, Inbred CBA; Organic Chemicals; Phagocytosis; Rosette Formation; Spleen; Surface-Active Agents; T-Lymphocytes; Tuberculosis, Pulmonary

1990