Page last updated: 2024-10-16

betaine and Deficiency, Folic Acid

betaine has been researched along with Deficiency, Folic Acid in 16 studies

glycine betaine : The amino acid betaine derived from glycine.

Research Excerpts

ExcerptRelevanceReference
"The effect of betaine status on folate deficiency-induced hyperhomocysteinemia was investigated to determine whether folate deficiency impairs homocysteine removal not only by the methionine synthase (MS) pathway but also by the betaine-homocysteine S-methyltransferase (BHMT) pathway."7.78Effects of betaine supplementation and choline deficiency on folate deficiency-induced hyperhomocysteinemia in rats. ( Liu, Y; Liu, YQ; Morita, T; Sugiyama, K, 2012)
"The effect of betaine status on folate deficiency-induced hyperhomocysteinemia was investigated to determine whether folate deficiency impairs homocysteine removal not only by the methionine synthase (MS) pathway but also by the betaine-homocysteine S-methyltransferase (BHMT) pathway."3.78Effects of betaine supplementation and choline deficiency on folate deficiency-induced hyperhomocysteinemia in rats. ( Liu, Y; Liu, YQ; Morita, T; Sugiyama, K, 2012)
"Betaine therapy was given for 2 years to a 2-year-old boy with 5,10-methylenetetrahydrofolate reductase deficiency."1.36Titration of betaine therapy to optimize therapy in an infant with 5,10-methylenetetrahydrofolate reductase deficiency. ( Berk, O; Blom, HJ; Coker, M; Koroğlu, OA; Kültürsay, N; Ucar, SK; Yalaz, M, 2010)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19904 (25.00)18.7374
1990's2 (12.50)18.2507
2000's1 (6.25)29.6817
2010's9 (56.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ganz, AB1
Shields, K1
Fomin, VG1
Lopez, YS1
Mohan, S1
Lovesky, J1
Chuang, JC1
Ganti, A1
Carrier, B1
Yan, J2
Taeswuan, S1
Cohen, VV1
Swersky, CC1
Stover, JA1
Vitiello, GA1
Malysheva, OV1
Mudrak, E1
Caudill, MA3
Robinson, JL1
McBreairty, LE1
Randell, EW1
Brunton, JA1
Bertolo, RF1
Ucar, SK1
Koroğlu, OA1
Berk, O1
Yalaz, M1
Kültürsay, N1
Blom, HJ1
Coker, M1
Christensen, KE1
Wu, Q3
Wang, X1
Deng, L2
Rozen, R3
Wang, W1
Gregory, JF1
Malysheva, O1
Brenna, JT1
Stabler, SP3
Allen, RH3
Schoendorfer, NC1
Obeid, R1
Moxon-Lester, L1
Sharp, N1
Vitetta, L1
Boyd, RN1
Davies, PS1
Liu, Y1
Liu, YQ1
Morita, T1
Sugiyama, K1
Serrano, M1
Pérez-Dueñas, B1
Montoya, J1
Ormazabal, A1
Artuch, R1
Mikael, LG1
Pancer, J1
Jiang, X1
Caudill, M1
STEKOL, JA1
WEISS, S1
ANDERSON, EI1
HSU, PT1
WATJEN, A1
Knock, E1
Lawrance, AK1
Wang, XL1
Lindenbaum, J2
Savage, DG1
Poirier, LA1
Whitehead, VM1
Keshavarz, K1
Fuller, HL1
Marston, HR1
Allen, SH1

Reviews

2 reviews available for betaine and Deficiency, Folic Acid

ArticleYear
Genetic causes of cerebral folate deficiency: clinical, biochemical and therapeutic aspects.
    Drug discovery today, 2012, Volume: 17, Issue:23-24

    Topics: Betaine; Cerebral Cortex; Folic Acid; Folic Acid Deficiency; Genetic Predisposition to Disease; Huma

2012
Metabolic abnormalities in cobalamin (vitamin B12) and folate deficiency.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1993, Volume: 7, Issue:14

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adolescent; Adult; Aged; Animals; Betaine

1993

Trials

2 trials available for betaine and Deficiency, Folic Acid

ArticleYear
Genetic impairments in folate enzymes increase dependence on dietary choline for phosphatidylcholine production at the expense of betaine synthesis.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2016, Volume: 30, Issue:10

    Topics: Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Genotype; Humans; Lactation; Meth

2016
MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline.
    The American journal of clinical nutrition, 2011, Volume: 93, Issue:2

    Topics: Adolescent; Adult; Betaine; Choline; Deuterium; Dietary Supplements; Folic Acid Deficiency; Genotype

2011

Other Studies

12 other studies available for betaine and Deficiency, Folic Acid

ArticleYear
Restriction of dietary methyl donors limits methionine availability and affects the partitioning of dietary methionine for creatine and phosphatidylcholine synthesis in the neonatal piglet.
    The Journal of nutritional biochemistry, 2016, Volume: 35

    Topics: Animals; Animals, Newborn; Betaine; Choline Deficiency; Creatine; Diet; Female; Folic Acid Deficienc

2016
Titration of betaine therapy to optimize therapy in an infant with 5,10-methylenetetrahydrofolate reductase deficiency.
    European journal of pediatrics, 2010, Volume: 169, Issue:2

    Topics: 5,10-Methylenetetrahydrofolate Reductase (FADH2); Betaine; Child, Preschool; Dose-Response Relations

2010
Steatosis in mice is associated with gender, folate intake, and expression of genes of one-carbon metabolism.
    The Journal of nutrition, 2010, Volume: 140, Issue:10

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-

2010
Methylation capacity in children with severe cerebral palsy.
    European journal of clinical investigation, 2012, Volume: 42, Issue:7

    Topics: Betaine; Biomarkers; Case-Control Studies; Cerebral Palsy; Child; Child, Preschool; Choline; Cystath

2012
Effects of betaine supplementation and choline deficiency on folate deficiency-induced hyperhomocysteinemia in rats.
    Journal of nutritional science and vitaminology, 2012, Volume: 58, Issue:2

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-

2012
Low dietary folate and methylenetetrahydrofolate reductase deficiency may lead to pregnancy complications through modulation of ApoAI and IFN-γ in spleen and placenta, and through reduction of methylation potential.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:4

    Topics: Animals; Apolipoprotein A-I; Betaine; Choline; Diet; Female; Folic Acid; Folic Acid Deficiency; Homo

2013
Vitamin B12 and folic acid in relation to methionine synthesis from betaine in vivo and invitro.
    The Journal of biological chemistry, 1957, Volume: 226, Issue:1

    Topics: Betaine; Choline; Folic Acid; Folic Acid Deficiency; Humans; Methionine; Vitamin B 12; Vitamin B 12

1957
Strain differences in mice highlight the role of DNA damage in neoplasia induced by low dietary folate.
    The Journal of nutrition, 2008, Volume: 138, Issue:4

    Topics: Animals; Betaine; Diet; DNA Damage; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Gast

2008
Serum betaine, N,N-dimethylglycine and N-methylglycine levels in patients with cobalamin and folate deficiency and related inborn errors of metabolism.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:11

    Topics: Adolescent; Adult; Aged; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Chromatography;

1993
Folate deficiency and formiminoglutamic acid excretion during chronic diethylnitrosamine administration to rats.
    Cancer research, 1973, Volume: 33, Issue:2

    Topics: Animals; Betaine; Carcinogens; Choline; Diet; Drinking; FIGLU Test; Folic Acid; Folic Acid Deficienc

1973
Relationship of arginine and methionine to creatine formation in chicks.
    The Journal of nutrition, 1971, Volume: 101, Issue:7

    Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Betaine; Body Weight; Ch

1971
Factors affecting formiminoglutamic acid excretion in vitamin B 12 deficiency.
    The Biochemical journal, 1970, Volume: 116, Issue:4

    Topics: Aminopterin; Animals; Betaine; Female; Folic Acid; Folic Acid Deficiency; Glutarates; Histidine; Mal

1970