betaine has been researched along with Cystic Fibrosis in 4 studies
glycine betaine : The amino acid betaine derived from glycine.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate relationships between altered plasma choline and PC homeostasis and markers of lung function and inflammation in CF." | 7.81 | Plasma phosphatidylcholine alterations in cystic fibrosis patients: impaired metabolism and correlation with lung function and inflammation. ( Bernhard, W; Grothe, J; Pynn, CJ; Raith, M; Riethmüller, J; Stoll, D; Tschürtz, SM, 2015) |
| "Choline is an important constituent of acetylcholine." | 6.76 | Plasma choline depletion is associated with decreased peripheral blood leukocyte acetylcholine in children with cystic fibrosis. ( Bay, BN; Davidson, AG; Hasman, D; Innis, SM; Slack, PJ, 2011) |
| "To investigate relationships between altered plasma choline and PC homeostasis and markers of lung function and inflammation in CF." | 3.81 | Plasma phosphatidylcholine alterations in cystic fibrosis patients: impaired metabolism and correlation with lung function and inflammation. ( Bernhard, W; Grothe, J; Pynn, CJ; Raith, M; Riethmüller, J; Stoll, D; Tschürtz, SM, 2015) |
| "Choline is an important constituent of acetylcholine." | 2.76 | Plasma choline depletion is associated with decreased peripheral blood leukocyte acetylcholine in children with cystic fibrosis. ( Bay, BN; Davidson, AG; Hasman, D; Innis, SM; Slack, PJ, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grothe, J | 1 |
| Riethmüller, J | 1 |
| Tschürtz, SM | 1 |
| Raith, M | 1 |
| Pynn, CJ | 1 |
| Stoll, D | 1 |
| Bernhard, W | 1 |
| Innis, SM | 2 |
| Davidson, AG | 1 |
| Bay, BN | 1 |
| Slack, PJ | 1 |
| Hasman, D | 2 |
| Behrends, V | 1 |
| Bundy, JG | 1 |
| Williams, HD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Choline Nutritional Status Of Children With Cystic Fibrosis X-Sectional Study[NCT01150136] | 57 participants (Actual) | Observational | 2007-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for betaine and Cystic Fibrosis
| Article | Year |
|---|---|
Plasma choline depletion is associated with decreased peripheral blood leukocyte acetylcholine in children with cystic fibrosis.
Topics: Acetylcholine; Adolescent; Betaine; Child; Child, Preschool; Choline; Cross-Sectional Studies; Cysti | 2011 |
Evidence of choline depletion and reduced betaine and dimethylglycine with increased homocysteine in plasma of children with cystic fibrosis.
Topics: Adolescent; Betaine; Case-Control Studies; Child; Choline Deficiency; Cystic Fibrosis; Homocysteine; | 2006 |
2 other studies available for betaine and Cystic Fibrosis
| Article | Year |
|---|---|
Plasma phosphatidylcholine alterations in cystic fibrosis patients: impaired metabolism and correlation with lung function and inflammation.
Topics: Adult; Arachidonic Acid; Betaine; Choline; Cystic Fibrosis; Deuterium; Docosahexaenoic Acids; Female | 2015 |
Differences in strategies to combat osmotic stress in Burkholderia cenocepacia elucidated by NMR-based metabolic profiling.
Topics: Betaine; Burkholderia cenocepacia; Cystic Fibrosis; Humans; Lung; Magnetic Resonance Spectroscopy; M | 2011 |