Page last updated: 2024-10-16

betaine and Chronic Lung Injury

betaine has been researched along with Chronic Lung Injury in 4 studies

glycine betaine : The amino acid betaine derived from glycine.

Research Excerpts

ExcerptRelevanceReference
"The aim of this research was to determine the anti-inflammatory effect of betaine on sepsis-induced acute respiratory distress syndrome (ARDS) in rats through histopathological examination, radiologic imaging, and biochemical analysis."8.31Anti-inflammatory and antioxidant properties of betaine protect against sepsis-induced acute lung injury: CT and histological evidence. ( Bora, ES; Çakır, A; Erbaş, O; Erdoğan, MA; Sorgun, O; Uyanıkgil, Y, 2023)
"The aim of this research was to determine the anti-inflammatory effect of betaine on sepsis-induced acute respiratory distress syndrome (ARDS) in rats through histopathological examination, radiologic imaging, and biochemical analysis."4.31Anti-inflammatory and antioxidant properties of betaine protect against sepsis-induced acute lung injury: CT and histological evidence. ( Bora, ES; Çakır, A; Erbaş, O; Erdoğan, MA; Sorgun, O; Uyanıkgil, Y, 2023)
"Betaine is a methyl donor utilized in regeneration of methionine from homocysteine in a metabolic reaction catalyzed by betaine-homocysteine methyltransferase (BHMT), an enzyme mostly localized in the liver."1.51Alleviation of paraquat-induced oxidative lung injury by betaine via regulation of sulfur-containing amino acid metabolism despite the lack of betaine-homocysteine methyltransferase (BHMT) in the lung. ( Choi, YJ; Jun, DS; Kim, YC; Na, JD, 2019)
"Betaine was administered orally (250 mg/kg) for a period of 21 days before burn injury, and single dose of betaine was administered after thermal injury."1.43Protective effect of betaine against burn-induced pulmonary injury in rats. ( Aykaç, A; Çetinel, Ş; Satılmış, B; Şehirli, AÖ; Şener, G; Tetik, Ş; Yeğen, B, 2016)
"Using a pig model, lung injury was induced with 5-ml/kg administration of a betaine-HCl/pepsin mixture via a flexible bronchoscope."1.35Ex vivo reconditioning of marginal donor lungs injured by acid aspiration. ( Ampollini, L; Arni, S; Hillinger, S; Inci, D; Inci, I; Jungraithmayr, W; Leskosek, B; Vogt, P; Weder, W, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Sorgun, O1
Çakır, A1
Bora, ES1
Erdoğan, MA1
Uyanıkgil, Y1
Erbaş, O1
Na, JD1
Choi, YJ1
Jun, DS1
Kim, YC1
Şehirli, AÖ1
Satılmış, B1
Tetik, Ş1
Çetinel, Ş1
Yeğen, B1
Aykaç, A1
Şener, G1
Inci, I1
Ampollini, L1
Arni, S1
Jungraithmayr, W1
Inci, D1
Hillinger, S1
Leskosek, B1
Vogt, P1
Weder, W1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Normothermic Ex Vivo Lung Perfusion (EVLP) For An Improved Assessment of Donor Lungs For Transplantation[NCT01190059]Phase 122 participants (Actual)Interventional2008-08-31Completed
Novel Lung Trial: Normothermic Ex Vivo Lung Perfusion (Evlp) As An Assessment Of Extended/Marginal Donor Lungs[NCT01365429]252 participants (Actual)Interventional2011-05-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for betaine and Chronic Lung Injury

ArticleYear
Anti-inflammatory and antioxidant properties of betaine protect against sepsis-induced acute lung injury: CT and histological evidence.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2023, Volume: 56

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Betaine; Lung; Lung Injury; Rats

2023
Alleviation of paraquat-induced oxidative lung injury by betaine via regulation of sulfur-containing amino acid metabolism despite the lack of betaine-homocysteine methyltransferase (BHMT) in the lung.
    Food & function, 2019, Feb-20, Volume: 10, Issue:2

    Topics: Amino Acids, Sulfur; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Cytokines; Gene Exp

2019
Protective effect of betaine against burn-induced pulmonary injury in rats.
    Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 2016, Volume: 22, Issue:5

    Topics: Administration, Oral; Animals; Antioxidants; Betaine; Burns; Cytokines; Disease Models, Animal; Fema

2016
Ex vivo reconditioning of marginal donor lungs injured by acid aspiration.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2008, Volume: 27, Issue:11

    Topics: Animals; Betaine; Gastric Acid; Humans; Hydrochloric Acid; Inhalation; Lung; Lung Injury; Lung Trans

2008
Ex vivo reconditioning of marginal donor lungs injured by acid aspiration.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2008, Volume: 27, Issue:11

    Topics: Animals; Betaine; Gastric Acid; Humans; Hydrochloric Acid; Inhalation; Lung; Lung Injury; Lung Trans

2008
Ex vivo reconditioning of marginal donor lungs injured by acid aspiration.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2008, Volume: 27, Issue:11

    Topics: Animals; Betaine; Gastric Acid; Humans; Hydrochloric Acid; Inhalation; Lung; Lung Injury; Lung Trans

2008
Ex vivo reconditioning of marginal donor lungs injured by acid aspiration.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2008, Volume: 27, Issue:11

    Topics: Animals; Betaine; Gastric Acid; Humans; Hydrochloric Acid; Inhalation; Lung; Lung Injury; Lung Trans

2008