Page last updated: 2024-10-16

betaine and Chronic Kidney Diseases

betaine has been researched along with Chronic Kidney Diseases in 11 studies

glycine betaine : The amino acid betaine derived from glycine.

Research Excerpts

ExcerptRelevanceReference
"Some studies on CKD animal models have shown the benefits of betaine supplementation, including decreased kidney damage, antioxidant recovery status, and decreased inflammation."5.22The Role of Betaine in Patients With Chronic Kidney Disease: a Narrative Review. ( Alvarenga, L; Ferreira, MS; Kemp, JA; Mafra, D, 2022)
"Hyperhomocysteinemia has undoubtedly a central role in such a prominent cardiovascular burden."2.66Vitamin B Supplementation and Nutritional Intake of Methyl Donors in Patients with Chronic Kidney Disease: A Critical Review of the Impact on Epigenetic Machinery. ( Bergamini, C; Capelli, I; Cappuccilli, M; Cianciolo, G; Conte, D; Donati, G; Giacomelli, FA; La Manna, G; Natali, T, 2020)
"In end-stage renal disease (ESRD), these same small molecules are used to determine dialysis dose and dialytic clearance."1.51Untargeted metabolomics reveals N, N, N-trimethyl-L-alanyl-L-proline betaine (TMAP) as a novel biomarker of kidney function. ( Garg, AX; House, AA; Lajoie, GA; Mio, MA; RaoPeters, AAE; Thomson, BKA; Tonial, NC; Urquhart, BL; Velenosi, TJ, 2019)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (36.36)24.3611
2020's7 (63.64)2.80

Authors

AuthorsStudies
Hall, JA1
Jewell, DE2
Ephraim, E2
Alvarenga, L1
Ferreira, MS1
Kemp, JA1
Mafra, D1
Kwan, B1
Fuhrer, T1
Montemayor, D1
Fink, JC1
He, J1
Hsu, CY1
Messer, K1
Nelson, RG1
Pu, M1
Ricardo, AC1
Rincon-Choles, H1
Shah, VO1
Ye, H1
Zhang, J1
Sharma, K1
Natarajan, L1
Pelletier, CC1
Croyal, M1
Ene, L1
Aguesse, A1
Billon-Crossouard, S1
Krempf, M1
Lemoine, S1
Guebre-Egziabher, F1
Juillard, L1
Soulage, CO1
Cappuccilli, M1
Bergamini, C1
Giacomelli, FA1
Cianciolo, G1
Donati, G1
Conte, D1
Natali, T1
La Manna, G1
Capelli, I1
Guo, F1
Dai, Q1
Zeng, X1
Liu, Y1
Tan, Z1
Zhang, H1
Ouyang, D1
Ebert, T1
Painer, J1
Bergman, P2
Qureshi, AR2
Giroud, S1
Stalder, G1
Kublickiene, K1
Göritz, F1
Vetter, S1
Bieber, C1
Fröbert, O1
Arnemo, JM1
Zedrosser, A1
Redtenbacher, I1
Shiels, PG1
Johnson, RJ1
Stenvinkel, P2
Xu, KY1
Xia, GH1
Lu, JQ1
Chen, MX1
Zhen, X1
Wang, S1
You, C1
Nie, J1
Zhou, HW1
Yin, J1
Velenosi, TJ1
Thomson, BKA1
Tonial, NC1
RaoPeters, AAE1
Mio, MA1
Lajoie, GA1
Garg, AX1
House, AA1
Urquhart, BL1
Missailidis, C1
Hällqvist, J1
Barany, P1
Heimbürger, O1
Lindholm, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Washed Microbiota Transplantation (WMT) for Chronic Kidney Disease (CKD): a Open Label, Multicenter Trial[NCT05838118]100 participants (Anticipated)Interventional2023-04-20Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for betaine and Chronic Kidney Diseases

ArticleYear
The Role of Betaine in Patients With Chronic Kidney Disease: a Narrative Review.
    Current nutrition reports, 2022, Volume: 11, Issue:3

    Topics: Animals; Antioxidants; Betaine; Dysbiosis; Humans; Inflammation; Renal Insufficiency, Chronic

2022
Vitamin B Supplementation and Nutritional Intake of Methyl Donors in Patients with Chronic Kidney Disease: A Critical Review of the Impact on Epigenetic Machinery.
    Nutrients, 2020, Apr-27, Volume: 12, Issue:5

    Topics: Betaine; Cardiovascular Diseases; Choline; Dietary Supplements; DNA Methylation; Eating; Epigenesis,

2020

Trials

1 trial available for betaine and Chronic Kidney Diseases

ArticleYear
Betaine and Soluble Fiber Improve Body Composition and Plasma Metabolites in Cats with Chronic Kidney Disease.
    Frontiers in bioscience (Elite edition), 2023, 04-04, Volume: 15, Issue:2

    Topics: Animals; Betaine; Body Composition; Cats; Dietary Supplements; Metabolome; Renal Insufficiency, Chro

2023

Other Studies

8 other studies available for betaine and Chronic Kidney Diseases

ArticleYear
Feeding cats with chronic kidney disease food supplemented with betaine and prebiotics increases total body mass and reduces uremic toxins.
    PloS one, 2022, Volume: 17, Issue:5

    Topics: Animals; Betaine; Body Weight; Cats; Cross-Over Studies; Feces; Prebiotics; Renal Insufficiency, Chr

2022
A generalized covariate-adjusted top-scoring pair algorithm with applications to diabetic kidney disease stage classification in the Chronic Renal Insufficiency Cohort (CRIC) Study.
    BMC bioinformatics, 2023, Feb-20, Volume: 24, Issue:1

    Topics: Algorithms; Betaine; Diabetes Mellitus; Diabetic Nephropathies; Humans; Metabolomics; Renal Insuffic

2023
Elevation of Trimethylamine-N-Oxide in Chronic Kidney Disease: Contribution of Decreased Glomerular Filtration Rate.
    Toxins, 2019, 11-01, Volume: 11, Issue:11

    Topics: Adult; Betaine; Choline; Creatinine; Female; Gastrointestinal Microbiome; Glomerular Filtration Rate

2019
Renal function is associated with plasma trimethylamine-N-oxide, choline, L-carnitine and betaine: a pilot study.
    International urology and nephrology, 2021, Volume: 53, Issue:3

    Topics: Betaine; Biomarkers; Carnitine; Choline; Female; Glomerular Filtration Rate; Humans; Kidney; Male; M

2021
Insights in the regulation of trimetylamine N-oxide production using a comparative biomimetic approach suggest a metabolic switch in hibernating bears.
    Scientific reports, 2020, 11-23, Volume: 10, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Animals; Betaine; Biomimetics; Cardiovascular Diseases; Choline; Fem

2020
Impaired renal function and dysbiosis of gut microbiota contribute to increased trimethylamine-N-oxide in chronic kidney disease patients.
    Scientific reports, 2017, 05-03, Volume: 7, Issue:1

    Topics: Adult; Aged; Animals; Betaine; Carnitine; Case-Control Studies; Choline; Clostridiaceae; Dysbiosis;

2017
Untargeted metabolomics reveals N, N, N-trimethyl-L-alanyl-L-proline betaine (TMAP) as a novel biomarker of kidney function.
    Scientific reports, 2019, 05-02, Volume: 9, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Betaine; Biomarkers; Creatinine; Female; Glomerular Filtration Rate;

2019
Serum Trimethylamine-N-Oxide Is Strongly Related to Renal Function and Predicts Outcome in Chronic Kidney Disease.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Adult; Aged; Betaine; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Choline; Female; Fibr

2016