Page last updated: 2024-10-16

betaine and Cerebro-Hepato-Renal Syndrome

betaine has been researched along with Cerebro-Hepato-Renal Syndrome in 2 studies

glycine betaine : The amino acid betaine derived from glycine.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, R1
Chen, L1
Jiralerspong, S1
Snowden, A1
Steinberg, S1
Braverman, N1
Chegary, M1
Te Brinke, H1
Doolaard, M1
Ijlst, L1
Wijburg, FA1
Wanders, RJ1
Houten, SM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot, Open Label Trial Assessing the Safety and Efficacy of Betaine in Children With Peroxisome Biogenesis Disorders.[NCT01838941]Phase 312 participants (Actual)Interventional2013-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Peroxisome Biochemical Functions as Measured by Plasma Very Long Chain Fatty Acid

C26/C22 ratio in plasma is a recognized biomarker for very long chain fatty acid (normal range: 0.002-0.018). It was measured twice before the beginning of treatment and measured once at the end. (NCT01838941)
Timeframe: 6 months

Interventionratio (Mean)
BaselineAt 6 months
Betaine0.1800.188

Other Studies

2 other studies available for betaine and Cerebro-Hepato-Renal Syndrome

ArticleYear
Recovery of PEX1-Gly843Asp peroxisome dysfunction by small-molecule compounds.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Mar-23, Volume: 107, Issue:12

    Topics: Adenosine Triphosphatases; Amino Acid Substitution; ATPases Associated with Diverse Cellular Activit

2010
Characterization of L-aminocarnitine, an inhibitor of fatty acid oxidation.
    Molecular genetics and metabolism, 2008, Volume: 93, Issue:4

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acetyl-CoA C-Acyltransferase; Acyl-CoA Dehydrogenase, Long-Chain;

2008