Page last updated: 2024-10-16

betaine and Brain Swelling

betaine has been researched along with Brain Swelling in 3 studies

glycine betaine : The amino acid betaine derived from glycine.

Research Excerpts

ExcerptRelevanceReference
"The clinical features of untreated CBS deficiency include myopia, ectopia lentis, mental retardation, skeletal anomalies resembling Marfan syndrome, and thromboembolic events."1.42Successive MRI Findings of Reversible Cerebral White Matter Lesions in a Patient with Cystathionine β-Synthase Deficiency. ( Asano, T; Fukao, T; Kawamoto, M; Kawamoto, N; Kimura, T; Matsui, E; Sasai, H; Shimozawa, N; Yamamoto, T, 2015)
"We conclude that the cerebral edema was most likely precipitated by the betaine therapy, although the exact mechanism is uncertain."1.31Progressive cerebral edema associated with high methionine levels and betaine therapy in a patient with cystathionine beta-synthase (CBS) deficiency. ( Allen, RH; Braverman, N; Geraghty, MT; Kashani, AH; Mudd, SH; Okoh, J; Pomper, M; Stabler, SP; Tangerman, A; Wagner, C; Yaghmai, R, 2002)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sasai, H1
Shimozawa, N1
Asano, T1
Kawamoto, N1
Yamamoto, T1
Kimura, T1
Kawamoto, M1
Matsui, E1
Fukao, T1
Devlin, AM1
Hajipour, L1
Gholkar, A1
Fernandes, H1
Ramesh, V1
Morris, AA1
Yaghmai, R1
Kashani, AH1
Geraghty, MT1
Okoh, J1
Pomper, M1
Tangerman, A1
Wagner, C1
Stabler, SP1
Allen, RH1
Mudd, SH1
Braverman, N1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Betaine for Reduction of Urine Oxalate in Patients With Type 1 Primary Hyperoxaluria[NCT00283387]Phase 215 participants (Actual)Interventional2007-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Urinary Oxalate Excretion

"The patients were randomly assigned oral betaine or placebo for 2 months, followed by a 2 month washout. Each patient then received the alternate study medication for 2 months.~Urinary Oxalate Excretion was measured by oxalate oxidase. Two 24 hour urine collections were obtained at baseline, and during the eighth week of each study period." (NCT00283387)
Timeframe: baseline, 2 months, 6 months

Interventionumol/mg (Mean)
Betaine1.43
Placebo1.04

Other Studies

3 other studies available for betaine and Brain Swelling

ArticleYear
Successive MRI Findings of Reversible Cerebral White Matter Lesions in a Patient with Cystathionine β-Synthase Deficiency.
    The Tohoku journal of experimental medicine, 2015, Volume: 237, Issue:4

    Topics: Betaine; Brain; Brain Edema; Cell Membrane; Diet, Protein-Restricted; Diffusion Magnetic Resonance I

2015
Cerebral edema associated with betaine treatment in classical homocystinuria.
    The Journal of pediatrics, 2004, Volume: 144, Issue:4

    Topics: Betaine; Brain Edema; Child, Preschool; Craniotomy; Cystathionine beta-Synthase; Decompression, Surg

2004
Progressive cerebral edema associated with high methionine levels and betaine therapy in a patient with cystathionine beta-synthase (CBS) deficiency.
    American journal of medical genetics, 2002, Feb-15, Volume: 108, Issue:1

    Topics: Betaine; Brain Edema; Child; Child, Preschool; Female; Homocystinuria; Humans; Infant; Infant, Newbo

2002