betaine has been researched along with Alzheimer Disease in 12 studies
glycine betaine : The amino acid betaine derived from glycine.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alzheimer's disease (AD) is a neurodegenerative disease, which is associated with malnutrition and hyperhomocysteine." | 9.24 | Association between malnutrition and hyperhomocysteine in Alzheimer's disease patients and diet intervention of betaine. ( Ding, S; Sun, J; Wen, S; Zhou, J, 2017) |
| "Alzheimer's disease (AD) is a neurodegenerative disease, which is associated with malnutrition and hyperhomocysteine." | 5.24 | Association between malnutrition and hyperhomocysteine in Alzheimer's disease patients and diet intervention of betaine. ( Ding, S; Sun, J; Wen, S; Zhou, J, 2017) |
| "Hyperhomocysteinemia (Hhcy) may induce memory deficits with β-amyloid (Aβ) accumulation and tau hyperphosphorylation." | 3.79 | Betaine attenuates Alzheimer-like pathological changes and memory deficits induced by homocysteine. ( Chai, GS; Cheng, XS; Jiang, X; Liu, GP; Ma, ZW; Ni, ZF; Wang, JZ; Wang, Q; Xie, AJ, 2013) |
| "In the pathophysiology of Alzheimer's disease, the deposition of amyloid β peptide (Aβ) is associated with oxidative stress, leading to cognitive impairment and neurodegeneration." | 1.72 | Preventive Effect of Betaine Against Cognitive Impairments in Amyloid β Peptide-Injected Mice Through Sirtuin1 in Hippocampus. ( Hiramatsu, M; Ibi, D; Kojima, Y; Kondo, S; Nakasai, G; Ohmi, A; Takaba, R, 2022) |
| "Low choline intake was associated with increased risks of incident dementia and AD." | 1.72 | Is dietary choline intake related to dementia and Alzheimer's disease risks? Results from the Framingham Heart Study. ( Ang, AF; Au, R; Auerbach, SH; Blusztajn, JK; Devine, SA; Jacques, PF; Liu, C; Liu, X; Massaro, J; Yuan, J, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 7 (58.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ibi, D | 2 |
| Kondo, S | 2 |
| Ohmi, A | 1 |
| Kojima, Y | 2 |
| Nakasai, G | 1 |
| Takaba, R | 1 |
| Hiramatsu, M | 2 |
| Ozaki, T | 1 |
| Yoshino, Y | 1 |
| Tachibana, A | 1 |
| Shimizu, H | 1 |
| Mori, T | 1 |
| Nakayama, T | 1 |
| Mawatari, K | 1 |
| Numata, S | 1 |
| Iga, JI | 1 |
| Takahashi, A | 1 |
| Ohmori, T | 1 |
| Ueno, SI | 1 |
| Moreno, RI | 1 |
| Zambelli, VO | 1 |
| Picolo, G | 1 |
| Cury, Y | 1 |
| Morandini, AC | 1 |
| Marques, AC | 1 |
| Sciani, JM | 1 |
| Yuan, J | 1 |
| Liu, X | 1 |
| Liu, C | 1 |
| Ang, AF | 1 |
| Massaro, J | 1 |
| Devine, SA | 1 |
| Auerbach, SH | 1 |
| Blusztajn, JK | 1 |
| Au, R | 1 |
| Jacques, PF | 1 |
| van Hummel, A | 1 |
| Taleski, G | 1 |
| Sontag, JM | 1 |
| Feiten, AF | 1 |
| Ke, YD | 1 |
| Ittner, LM | 1 |
| Sontag, E | 1 |
| McCarty, MF | 1 |
| O'Keefe, JH | 1 |
| DiNicolantonio, JJ | 1 |
| Zhuang, Z | 1 |
| Gao, M | 1 |
| Yang, R | 1 |
| Liu, Z | 1 |
| Cao, W | 1 |
| Huang, T | 1 |
| Hirashima, K | 1 |
| Sumiya, K | 1 |
| Yamamoto, M | 1 |
| Ando, T | 1 |
| Sun, J | 1 |
| Wen, S | 1 |
| Zhou, J | 1 |
| Ding, S | 1 |
| Robertson, DS | 1 |
| Chai, GS | 1 |
| Jiang, X | 1 |
| Ni, ZF | 1 |
| Ma, ZW | 1 |
| Xie, AJ | 1 |
| Cheng, XS | 1 |
| Wang, Q | 1 |
| Wang, JZ | 1 |
| Liu, GP | 1 |
| Näslund, J | 1 |
| Karlström, AR | 1 |
| Tjernberg, LO | 1 |
| Schierhorn, A | 1 |
| Terenius, L | 1 |
| Nordstedt, C | 1 |
1 trial available for betaine and Alzheimer Disease
| Article | Year |
|---|---|
Association between malnutrition and hyperhomocysteine in Alzheimer's disease patients and diet intervention of betaine.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Betaine; Case-Control Studies; Dementia; Dietary Supplem | 2017 |
11 other studies available for betaine and Alzheimer Disease
| Article | Year |
|---|---|
Preventive Effect of Betaine Against Cognitive Impairments in Amyloid β Peptide-Injected Mice Through Sirtuin1 in Hippocampus.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Betaine; Cognitive Dysfunction; Disease Models, A | 2022 |
Metabolomic alterations in the blood plasma of older adults with mild cognitive impairment and Alzheimer's disease (from the Nakayama Study).
Topics: Activities of Daily Living; Aged; Alzheimer Disease; Betaine; Biomarkers; Cognitive Dysfunction; Hum | 2022 |
Caspase-1 and Cathepsin B Inhibitors from Marine Invertebrates, Aiming at a Reduction in Neuroinflammation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Aquatic Organisms; Betaine; Caspase 1; Cathepsin | 2022 |
Is dietary choline intake related to dementia and Alzheimer's disease risks? Results from the Framingham Heart Study.
Topics: Adult; Alzheimer Disease; Animals; Betaine; Choline; Eating; Female; Humans; Longitudinal Studies; M | 2022 |
Methyl donor supplementation reduces phospho-Tau, Fyn and demethylated protein phosphatase 2A levels and mitigates learning and motor deficits in a mouse model of tauopathy.
Topics: Alzheimer Disease; Animals; Betaine; Carbon; Choline; Dietary Supplements; Disease Models, Animal; F | 2023 |
A diet rich in taurine, cysteine, folate, B
Topics: Alzheimer Disease; Animals; Betaine; Brain; Cysteine; Diet; Dietary Supplements; Folic Acid; Gases; | 2019 |
Causal relationships between gut metabolites and Alzheimer's disease: a bidirectional Mendelian randomization study.
Topics: Alzheimer Disease; Betaine; Carnitine; Choline; Female; Gastrointestinal Microbiome; Genetic Predisp | 2021 |
Preventive Effects of Continuous Betaine Intake on Cognitive Impairment and Aberrant Gene Expression in Hippocampus of 3xTg Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Betaine; Cognition; Cognitive Dysfunction; Diseas | 2021 |
Proposed biochemistry of Parkinson's and Alzheimer's diseases.
Topics: Aldehydes; Alzheimer Disease; Aspartic Acid; Betaine; Brain; Disease Progression; Humans; Kynurenine | 2017 |
Betaine attenuates Alzheimer-like pathological changes and memory deficits induced by homocysteine.
Topics: Alzheimer Disease; Animals; Betaine; Disease Models, Animal; Homocysteine; Hyperhomocysteinemia; Lip | 2013 |
High-resolution separation of amyloid beta-peptides: structural variants present in Alzheimer's disease amyloid.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Betaine; Brain Chemistry; Chromatogra | 1996 |