betaine has been researched along with Alcoholic Fatty Liver in 10 studies
glycine betaine : The amino acid betaine derived from glycine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results strongly suggest that alcohol may modulate both apoptotic and fat synthetic gene expression through homocysteine-induced ER stress in chronic alcoholic mouse liver and that correction of hyperhomocysteinemia by betaine or other approaches may be useful to prevent alcoholic liver disease." | 7.72 | Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice. ( Ji, C; Kaplowitz, N, 2003) |
| "The results strongly suggest that alcohol may modulate both apoptotic and fat synthetic gene expression through homocysteine-induced ER stress in chronic alcoholic mouse liver and that correction of hyperhomocysteinemia by betaine or other approaches may be useful to prevent alcoholic liver disease." | 3.72 | Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice. ( Ji, C; Kaplowitz, N, 2003) |
| "Betaine has previously been demonstrated to protect the liver against alcohol‑induced fat accumulation." | 1.46 | Betaine attenuates chronic alcohol‑induced fatty liver by broadly regulating hepatic lipid metabolism. ( Chen, M; Gao, J; Huang, L; Huang, Z; Li, J; Liu, R; Tai, Y; Tang, C; Wen, S; Yang, W, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, W | 1 |
| Huang, L | 1 |
| Gao, J | 1 |
| Wen, S | 1 |
| Tai, Y | 1 |
| Chen, M | 1 |
| Huang, Z | 1 |
| Liu, R | 1 |
| Tang, C | 1 |
| Li, J | 1 |
| Medici, V | 1 |
| Schroeder, DI | 1 |
| Woods, R | 1 |
| LaSalle, JM | 1 |
| Geng, Y | 1 |
| Shibata, NM | 1 |
| Peerson, J | 1 |
| Hodzic, E | 1 |
| Dayal, S | 1 |
| Tsukamoto, H | 1 |
| Kharbanda, KK | 2 |
| Tillman, B | 1 |
| French, SW | 1 |
| Halsted, CH | 1 |
| Varatharajalu, R | 1 |
| Garige, M | 1 |
| Leckey, LC | 1 |
| Arellanes-Robledo, J | 1 |
| Reyes-Gordillo, K | 1 |
| Shah, R | 1 |
| Lakshman, MR | 1 |
| Wang, Z | 1 |
| Yao, T | 1 |
| Song, Z | 1 |
| Ji, C | 2 |
| Kaplowitz, N | 2 |
| Chan, C | 1 |
| Samara, K | 1 |
| Liu, C | 1 |
| Soldevila-Pico, C | 1 |
| Nelson, DR | 1 |
| Abdelmalek, MF | 1 |
| Mailliard, ME | 1 |
| Baldwin, CR | 1 |
| Beckenhauer, HC | 3 |
| Sorrell, MF | 1 |
| Tuma, DJ | 3 |
| Barak, AJ | 2 |
| Junnila, M | 1 |
| Badakhsh, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Betaine for Reduction of Urine Oxalate in Patients With Type 1 Primary Hyperoxaluria[NCT00283387] | Phase 2 | 15 participants (Actual) | Interventional | 2007-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"The patients were randomly assigned oral betaine or placebo for 2 months, followed by a 2 month washout. Each patient then received the alternate study medication for 2 months.~Urinary Oxalate Excretion was measured by oxalate oxidase. Two 24 hour urine collections were obtained at baseline, and during the eighth week of each study period." (NCT00283387)
Timeframe: baseline, 2 months, 6 months
| Intervention | umol/mg (Mean) |
|---|---|
| Betaine | 1.43 |
| Placebo | 1.04 |
10 other studies available for betaine and Alcoholic Fatty Liver
| Article | Year |
|---|---|
Betaine attenuates chronic alcohol‑induced fatty liver by broadly regulating hepatic lipid metabolism.
Topics: Adiponectin; Alcohol Drinking; Animals; Betaine; Diacylglycerol O-Acyltransferase; Fatty Acid Syntha | 2017 |
Methylation and gene expression responses to ethanol feeding and betaine supplementation in the cystathionine beta synthase-deficient mouse.
Topics: Animals; Betaine; Dietary Supplements; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Meth | 2014 |
Adverse signaling of scavenger receptor class B1 and PGC1s in alcoholic hepatosteatosis and steatohepatitis and protection by betaine in rat.
Topics: Adiponectin; Alanine Transaminase; Animals; Betaine; Diet, High-Fat; Ethanol; Fatty Liver; Fatty Liv | 2014 |
Involvement and mechanism of DGAT2 upregulation in the pathogenesis of alcoholic fatty liver disease.
Topics: Alcohols; Animals; Betaine; Diacylglycerol O-Acyltransferase; Enzyme Activation; Enzyme Induction; E | 2010 |
Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice.
Topics: Animals; Betaine; Central Nervous System Depressants; Disease Models, Animal; Endoplasmic Reticulum; | 2003 |
Predominant role of sterol response element binding proteins (SREBP) lipogenic pathways in hepatic steatosis in the murine intragastric ethanol feeding model.
Topics: Alanine Transaminase; Animals; Betaine; Biosynthetic Pathways; Central Nervous System Depressants; E | 2006 |
Betaine resolves severe alcohol-induced hepatitis and steatosis following liver transplantation.
Topics: Adult; Betaine; Biomarkers; Combined Modality Therapy; Fatty Liver, Alcoholic; Female; Hepatitis, Al | 2006 |
Betaine attenuates alcoholic steatosis by restoring phosphatidylcholine generation via the phosphatidylethanolamine methyltransferase pathway.
Topics: Animals; Betaine; Diet; Ethanol; Fatty Liver, Alcoholic; Lipotropic Agents; Liver; Male; Phosphatidy | 2007 |
Dietary betaine promotes generation of hepatic S-adenosylmethionine and protects the liver from ethanol-induced fatty infiltration.
Topics: Animals; Betaine; Fatty Liver, Alcoholic; Liver; Male; Methionine; Rats; Rats, Sprague-Dawley; S-Ade | 1993 |
The effect of betaine in reversing alcoholic steatosis.
Topics: Animals; Betaine; Fatty Liver, Alcoholic; Gastrointestinal Agents; Lipotropic Agents; Liver; Male; R | 1997 |