betaine has been researched along with Aging in 21 studies
glycine betaine : The amino acid betaine derived from glycine.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Excerpt | Relevance | Reference |
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"Betaine is an important human nutrient obtained from various foods." | 5.33 | Betaine suppresses proinflammatory signaling during aging: the involvement of nuclear factor-kappaB via nuclear factor-inducing kinase/IkappaB kinase and mitogen-activated protein kinases. ( Chung, HY; Go, EK; Jung, KJ; Kim, JY; Yu, BP, 2005) |
"Choline is an essential nutrient and can also be obtained by de novo synthesis via an oestrogen responsive pathway." | 2.77 | Choline supplementation and measures of choline and betaine status: a randomised, controlled trial in postmenopausal women. ( Bonham, MP; Duffy, ME; McCormack, JM; McNulty, H; Molloy, AM; Robson, PJ; Scott, JM; Strain, JJ; Ueland, PM; Wallace, JM; Walsh, PM; Ward, M, 2012) |
"Betaine promotes muscle protein synthesis via tethering mammalian target of rapamycin complex1 protein kinase (mTORC1) on the lysosomal membrane thereby activating mTORC1 signaling." | 1.62 | Betaine Delayed Muscle Loss by Attenuating Samtor Complex Inhibition for mTORC1 Signaling Via Increasing SAM Level. ( Chen, S; Fang, AP; He, TT; Hou, MJ; Long, JA; Lu, XT; Luo, Y; Tan, XY; Tang, ZH; Yishake, D; Zhong, RH; Zhu, HL, 2021) |
"Betaine was associated with the KOLT, TMT-A and COWAT, but after adjustments for potential confounders, the associations lost significance." | 1.39 | Plasma free choline, betaine and cognitive performance: the Hordaland Health Study. ( Bjelland, I; Drevon, CA; Engedal, K; Nurk, E; Nygaard, HA; Refsum, H; Smith, DA; Tell, GS; Ueland, PM; Vollset, SE, 2013) |
"Carnitine biosynthesis was assessed in human infants by measuring changes in plasma carnitine concentration and rates of urinary carnitine excretion after infants were fed carnitine-free formulas with and without added epsilon-N-trimethyl-L-lysine or gamma-butyrobetaine." | 1.27 | gamma-Butyrobetaine hydroxylase activity is not rate limiting for carnitine biosynthesis in the human infant. ( Olson, AL; Rebouche, CJ, 1987) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (19.05) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 5 (23.81) | 29.6817 |
2010's | 8 (38.10) | 24.3611 |
2020's | 4 (19.05) | 2.80 |
Authors | Studies |
---|---|
Long, JA | 2 |
Zhong, RH | 2 |
Chen, S | 2 |
Wang, F | 1 |
Luo, Y | 2 |
Lu, XT | 2 |
Yishake, D | 2 |
Chen, YM | 1 |
Fang, AP | 2 |
Zhu, HL | 2 |
He, TT | 1 |
Tan, XY | 1 |
Hou, MJ | 1 |
Tang, ZH | 1 |
Craven, H | 1 |
McGuinness, D | 1 |
Buchanan, S | 1 |
Galbraith, N | 1 |
McGuinness, DH | 1 |
Jones, B | 1 |
Combet, E | 1 |
Mafra, D | 1 |
Bergman, P | 1 |
Ellaway, A | 1 |
Stenvinkel, P | 1 |
Ijaz, UZ | 1 |
Shiels, PG | 1 |
Gillies, NA | 1 |
Franzke, B | 1 |
Wessner, B | 1 |
Schober-Halper, B | 1 |
Hofmann, M | 1 |
Oesen, S | 1 |
Tosevska, A | 1 |
Strasser, EM | 1 |
Roy, NC | 1 |
Milan, AM | 1 |
Cameron-Smith, D | 1 |
Wagner, KH | 1 |
Jarak, I | 1 |
Almeida, S | 1 |
Carvalho, RA | 1 |
Sousa, M | 1 |
Barros, A | 1 |
Alves, MG | 1 |
Oliveira, PF | 1 |
Hoffman, JM | 1 |
Ross, C | 1 |
Tran, V | 1 |
Promislow, DEL | 1 |
Tardif, S | 1 |
Jones, DP | 1 |
Lee, EK | 1 |
Jang, EJ | 1 |
Jung, KJ | 3 |
Kim, DH | 1 |
Yu, BP | 3 |
Chung, HY | 3 |
Çoban, J | 1 |
Bingül, I | 1 |
Yesil-Mizrak, K | 1 |
Dogru-Abbasoglu, S | 1 |
Oztezcan, S | 1 |
Uysal, M | 1 |
Hu, Y | 1 |
Sun, Q | 1 |
Zong, Y | 1 |
Liu, J | 1 |
Idriss, AA | 1 |
Omer, NA | 1 |
Zhao, R | 1 |
Cholewa, JM | 1 |
Dardevet, D | 1 |
Lima-Soares, F | 1 |
de Araújo Pessôa, K | 1 |
Oliveira, PH | 1 |
Dos Santos Pinho, JR | 1 |
Nicastro, H | 1 |
Xia, Z | 1 |
Cabido, CE | 1 |
Zanchi, NE | 1 |
Clow, KA | 1 |
Treberg, JR | 1 |
Brosnan, ME | 1 |
Brosnan, JT | 1 |
Wallace, JM | 1 |
McCormack, JM | 1 |
McNulty, H | 1 |
Walsh, PM | 1 |
Robson, PJ | 1 |
Bonham, MP | 1 |
Duffy, ME | 1 |
Ward, M | 1 |
Molloy, AM | 1 |
Scott, JM | 1 |
Ueland, PM | 2 |
Strain, JJ | 1 |
Nurk, E | 1 |
Refsum, H | 1 |
Bjelland, I | 1 |
Drevon, CA | 1 |
Tell, GS | 1 |
Vollset, SE | 1 |
Engedal, K | 1 |
Nygaard, HA | 1 |
Smith, DA | 1 |
Go, EK | 2 |
Kim, JY | 1 |
Sparks, JD | 1 |
Collins, HL | 1 |
Chirieac, DV | 1 |
Cianci, J | 1 |
Jokinen, J | 1 |
Sowden, MP | 1 |
Galloway, CA | 1 |
Sparks, CE | 1 |
Pillai, PB | 1 |
Fanatico, AC | 1 |
Blair, ME | 1 |
Emmert, JL | 1 |
Kim, JM | 1 |
Lim, H | 1 |
Lim, HK | 1 |
Barak, AJ | 1 |
Kemmy, RJ | 1 |
Olson, AL | 1 |
Rebouche, CJ | 1 |
Zapadniuk, VI | 1 |
Panteleĭmonova, TN | 1 |
Finkelstein, JD | 1 |
Kyle, W | 1 |
Harris, BJ | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
The Effect of Culinary Medicine to Enhance Protein Intake on Muscle Quality in Older Adults[NCT06157385] | 46 participants (Anticipated) | Interventional | 2023-05-06 | Recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 review available for betaine and Aging
Article | Year |
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Dietary proteins and amino acids in the control of the muscle mass during immobilization and aging: role of the MPS response.
Topics: Aging; Antioxidants; Betaine; Dietary Proteins; Dietary Supplements; Exercise; Glycine; Humans; Hypo | 2017 |
3 trials available for betaine and Aging
Article | Year |
---|---|
Nutritional supplementation alters associations between one-carbon metabolites and cardiometabolic risk profiles in older adults: a secondary analysis of the Vienna Active Ageing Study.
Topics: Aged; Aging; Betaine; Carbon; Cardiovascular Diseases; Choline; Dietary Supplements; Female; Homocys | 2022 |
Choline supplementation and measures of choline and betaine status: a randomised, controlled trial in postmenopausal women.
Topics: Aged; Aging; Betaine; Biomarkers; Choline; Choline Deficiency; Dietary Supplements; Double-Blind Met | 2012 |
Homocysteine remethylation in broilers fed surfeit choline or betaine and varying levels and sources of methionine from eight to twenty-two days of age.
Topics: Aging; Animal Feed; Animals; Betaine; Chickens; Choline; Dose-Response Relationship, Drug; Homocyste | 2006 |
17 other studies available for betaine and Aging
Article | Year |
---|---|
Dietary betaine intake is associated with skeletal muscle mass change over 3 years in middle-aged adults: the Guangzhou Nutrition and Health Study.
Topics: Aging; Betaine; Body Composition; Body Mass Index; China; Cohort Studies; Diet; Female; Humans; Male | 2021 |
Betaine Delayed Muscle Loss by Attenuating Samtor Complex Inhibition for mTORC1 Signaling Via Increasing SAM Level.
Topics: Aging; Animals; Betaine; Gene Expression Regulation; Intracellular Membranes; Intracellular Signalin | 2021 |
Socioeconomic position links circulatory microbiota differences with biological age.
Topics: Adult; Aged; Aging; Bacteria; Betaine; Female; Humans; Life Style; Male; Methylamines; Middle Aged; | 2021 |
Senescence and declining reproductive potential: Insight into molecular mechanisms through testicular metabolomics.
Topics: Aging; Animals; Betaine; Creatine; Fertility; Glutathione; Magnetic Resonance Spectroscopy; Male; Me | 2018 |
The metabolome as a biomarker of mortality risk in the common marmoset.
Topics: Aging; Animal Husbandry; Animals; Betaine; Biomarkers; Callithrix; Female; Male; Metabolome; Methion | 2019 |
Betaine attenuates lysophosphatidylcholine-mediated adhesion molecules in aged rat aorta: modulation of the nuclear factor-κB pathway.
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aorta; Betaine; Cell Adhesion | 2013 |
Effects of carnosine plus vitamin E and betaine treatments on oxidative stress in some tissues of aged rats.
Topics: Aging; Animals; Antioxidants; Betaine; Body Weight; Brain; Carnosine; Glutathione; Lipid Peroxidatio | 2013 |
Prenatal betaine exposure alleviates corticosterone-induced inhibition of CYP27A1 expression in the liver of juvenile chickens associated with its promoter DNA methylation.
Topics: Aging; Animals; Animals, Newborn; Anti-Inflammatory Agents; Betaine; Blotting, Western; Chickens; Ch | 2017 |
Elevated tissue betaine contents in developing rats are due to dietary betaine, not to synthesis.
Topics: Aging; Animals; Betaine; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Female; Male; | 2008 |
Plasma free choline, betaine and cognitive performance: the Hordaland Health Study.
Topics: Aged; Aging; Betaine; Biomarkers; Choline; Choline Deficiency; Cognitive Dysfunction; Cohort Studies | 2013 |
Betaine suppresses proinflammatory signaling during aging: the involvement of nuclear factor-kappaB via nuclear factor-inducing kinase/IkappaB kinase and mitogen-activated protein kinases.
Topics: Aging; Animals; Anti-Inflammatory Agents; Betaine; Cells, Cultured; Cyclooxygenase 2; Enzyme Activat | 2005 |
Hepatic very-low-density lipoprotein and apolipoprotein B production are increased following in vivo induction of betaine-homocysteine S-methyltransferase.
Topics: Aging; Animals; Apolipoproteins B; Betaine; Betaine-Homocysteine S-Methyltransferase; Diet; Enzyme I | 2006 |
Betaine modulates age-related NF-kappaB by thiol-enhancing action.
Topics: Aging; Animals; Antioxidants; Betaine; Blotting, Western; Body Weight; Cell Nucleus; Cells, Cultured | 2007 |
Methotrexate effects on hepatic betaine levels in choline-supplemented and choline-deficient rats.
Topics: Aging; Animals; Betaine; Choline; Choline Deficiency; Liver; Male; Methionine; Methotrexate; Rats; R | 1982 |
gamma-Butyrobetaine hydroxylase activity is not rate limiting for carnitine biosynthesis in the human infant.
Topics: Adolescent; Adult; Aged; Aging; Betaine; Carnitine; Child, Preschool; Female; gamma-Butyrobetaine Di | 1987 |
[Cholagogic effect of trimethylglycine in normal animals of different ages and in experimental atherosclerosis].
Topics: Aging; Animals; Arteriosclerosis; Betaine; Bile; Cholagogues and Choleretics; Cholic Acids; Dehydroc | 1987 |
Methionine metabolism in mammals. Regulation of homocysteine methyltransferases in rat tissue.
Topics: Aging; Alloxan; Animals; Betaine; Chromatography, Gel; Cycloheximide; Cysteine; Dactinomycin; Dietar | 1971 |