betaine has been researched along with Aging in 21 studies
glycine betaine : The amino acid betaine derived from glycine.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Betaine is an important human nutrient obtained from various foods." | 5.33 | Betaine suppresses proinflammatory signaling during aging: the involvement of nuclear factor-kappaB via nuclear factor-inducing kinase/IkappaB kinase and mitogen-activated protein kinases. ( Chung, HY; Go, EK; Jung, KJ; Kim, JY; Yu, BP, 2005) |
| "Choline is an essential nutrient and can also be obtained by de novo synthesis via an oestrogen responsive pathway." | 2.77 | Choline supplementation and measures of choline and betaine status: a randomised, controlled trial in postmenopausal women. ( Bonham, MP; Duffy, ME; McCormack, JM; McNulty, H; Molloy, AM; Robson, PJ; Scott, JM; Strain, JJ; Ueland, PM; Wallace, JM; Walsh, PM; Ward, M, 2012) |
| "Betaine promotes muscle protein synthesis via tethering mammalian target of rapamycin complex1 protein kinase (mTORC1) on the lysosomal membrane thereby activating mTORC1 signaling." | 1.62 | Betaine Delayed Muscle Loss by Attenuating Samtor Complex Inhibition for mTORC1 Signaling Via Increasing SAM Level. ( Chen, S; Fang, AP; He, TT; Hou, MJ; Long, JA; Lu, XT; Luo, Y; Tan, XY; Tang, ZH; Yishake, D; Zhong, RH; Zhu, HL, 2021) |
| "Betaine was associated with the KOLT, TMT-A and COWAT, but after adjustments for potential confounders, the associations lost significance." | 1.39 | Plasma free choline, betaine and cognitive performance: the Hordaland Health Study. ( Bjelland, I; Drevon, CA; Engedal, K; Nurk, E; Nygaard, HA; Refsum, H; Smith, DA; Tell, GS; Ueland, PM; Vollset, SE, 2013) |
| "Carnitine biosynthesis was assessed in human infants by measuring changes in plasma carnitine concentration and rates of urinary carnitine excretion after infants were fed carnitine-free formulas with and without added epsilon-N-trimethyl-L-lysine or gamma-butyrobetaine." | 1.27 | gamma-Butyrobetaine hydroxylase activity is not rate limiting for carnitine biosynthesis in the human infant. ( Olson, AL; Rebouche, CJ, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (19.05) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 8 (38.10) | 24.3611 |
| 2020's | 4 (19.05) | 2.80 |
| Authors | Studies |
|---|---|
| Long, JA | 2 |
| Zhong, RH | 2 |
| Chen, S | 2 |
| Wang, F | 1 |
| Luo, Y | 2 |
| Lu, XT | 2 |
| Yishake, D | 2 |
| Chen, YM | 1 |
| Fang, AP | 2 |
| Zhu, HL | 2 |
| He, TT | 1 |
| Tan, XY | 1 |
| Hou, MJ | 1 |
| Tang, ZH | 1 |
| Craven, H | 1 |
| McGuinness, D | 1 |
| Buchanan, S | 1 |
| Galbraith, N | 1 |
| McGuinness, DH | 1 |
| Jones, B | 1 |
| Combet, E | 1 |
| Mafra, D | 1 |
| Bergman, P | 1 |
| Ellaway, A | 1 |
| Stenvinkel, P | 1 |
| Ijaz, UZ | 1 |
| Shiels, PG | 1 |
| Gillies, NA | 1 |
| Franzke, B | 1 |
| Wessner, B | 1 |
| Schober-Halper, B | 1 |
| Hofmann, M | 1 |
| Oesen, S | 1 |
| Tosevska, A | 1 |
| Strasser, EM | 1 |
| Roy, NC | 1 |
| Milan, AM | 1 |
| Cameron-Smith, D | 1 |
| Wagner, KH | 1 |
| Jarak, I | 1 |
| Almeida, S | 1 |
| Carvalho, RA | 1 |
| Sousa, M | 1 |
| Barros, A | 1 |
| Alves, MG | 1 |
| Oliveira, PF | 1 |
| Hoffman, JM | 1 |
| Ross, C | 1 |
| Tran, V | 1 |
| Promislow, DEL | 1 |
| Tardif, S | 1 |
| Jones, DP | 1 |
| Lee, EK | 1 |
| Jang, EJ | 1 |
| Jung, KJ | 3 |
| Kim, DH | 1 |
| Yu, BP | 3 |
| Chung, HY | 3 |
| Çoban, J | 1 |
| Bingül, I | 1 |
| Yesil-Mizrak, K | 1 |
| Dogru-Abbasoglu, S | 1 |
| Oztezcan, S | 1 |
| Uysal, M | 1 |
| Hu, Y | 1 |
| Sun, Q | 1 |
| Zong, Y | 1 |
| Liu, J | 1 |
| Idriss, AA | 1 |
| Omer, NA | 1 |
| Zhao, R | 1 |
| Cholewa, JM | 1 |
| Dardevet, D | 1 |
| Lima-Soares, F | 1 |
| de Araújo Pessôa, K | 1 |
| Oliveira, PH | 1 |
| Dos Santos Pinho, JR | 1 |
| Nicastro, H | 1 |
| Xia, Z | 1 |
| Cabido, CE | 1 |
| Zanchi, NE | 1 |
| Clow, KA | 1 |
| Treberg, JR | 1 |
| Brosnan, ME | 1 |
| Brosnan, JT | 1 |
| Wallace, JM | 1 |
| McCormack, JM | 1 |
| McNulty, H | 1 |
| Walsh, PM | 1 |
| Robson, PJ | 1 |
| Bonham, MP | 1 |
| Duffy, ME | 1 |
| Ward, M | 1 |
| Molloy, AM | 1 |
| Scott, JM | 1 |
| Ueland, PM | 2 |
| Strain, JJ | 1 |
| Nurk, E | 1 |
| Refsum, H | 1 |
| Bjelland, I | 1 |
| Drevon, CA | 1 |
| Tell, GS | 1 |
| Vollset, SE | 1 |
| Engedal, K | 1 |
| Nygaard, HA | 1 |
| Smith, DA | 1 |
| Go, EK | 2 |
| Kim, JY | 1 |
| Sparks, JD | 1 |
| Collins, HL | 1 |
| Chirieac, DV | 1 |
| Cianci, J | 1 |
| Jokinen, J | 1 |
| Sowden, MP | 1 |
| Galloway, CA | 1 |
| Sparks, CE | 1 |
| Pillai, PB | 1 |
| Fanatico, AC | 1 |
| Blair, ME | 1 |
| Emmert, JL | 1 |
| Kim, JM | 1 |
| Lim, H | 1 |
| Lim, HK | 1 |
| Barak, AJ | 1 |
| Kemmy, RJ | 1 |
| Olson, AL | 1 |
| Rebouche, CJ | 1 |
| Zapadniuk, VI | 1 |
| Panteleĭmonova, TN | 1 |
| Finkelstein, JD | 1 |
| Kyle, W | 1 |
| Harris, BJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Culinary Medicine to Enhance Protein Intake on Muscle Quality in Older Adults[NCT06157385] | 46 participants (Anticipated) | Interventional | 2023-05-06 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for betaine and Aging
| Article | Year |
|---|---|
Dietary proteins and amino acids in the control of the muscle mass during immobilization and aging: role of the MPS response.
Topics: Aging; Antioxidants; Betaine; Dietary Proteins; Dietary Supplements; Exercise; Glycine; Humans; Hypo | 2017 |
3 trials available for betaine and Aging
| Article | Year |
|---|---|
Nutritional supplementation alters associations between one-carbon metabolites and cardiometabolic risk profiles in older adults: a secondary analysis of the Vienna Active Ageing Study.
Topics: Aged; Aging; Betaine; Carbon; Cardiovascular Diseases; Choline; Dietary Supplements; Female; Homocys | 2022 |
Choline supplementation and measures of choline and betaine status: a randomised, controlled trial in postmenopausal women.
Topics: Aged; Aging; Betaine; Biomarkers; Choline; Choline Deficiency; Dietary Supplements; Double-Blind Met | 2012 |
Homocysteine remethylation in broilers fed surfeit choline or betaine and varying levels and sources of methionine from eight to twenty-two days of age.
Topics: Aging; Animal Feed; Animals; Betaine; Chickens; Choline; Dose-Response Relationship, Drug; Homocyste | 2006 |
17 other studies available for betaine and Aging
| Article | Year |
|---|---|
Dietary betaine intake is associated with skeletal muscle mass change over 3 years in middle-aged adults: the Guangzhou Nutrition and Health Study.
Topics: Aging; Betaine; Body Composition; Body Mass Index; China; Cohort Studies; Diet; Female; Humans; Male | 2021 |
Betaine Delayed Muscle Loss by Attenuating Samtor Complex Inhibition for mTORC1 Signaling Via Increasing SAM Level.
Topics: Aging; Animals; Betaine; Gene Expression Regulation; Intracellular Membranes; Intracellular Signalin | 2021 |
Socioeconomic position links circulatory microbiota differences with biological age.
Topics: Adult; Aged; Aging; Bacteria; Betaine; Female; Humans; Life Style; Male; Methylamines; Middle Aged; | 2021 |
Senescence and declining reproductive potential: Insight into molecular mechanisms through testicular metabolomics.
Topics: Aging; Animals; Betaine; Creatine; Fertility; Glutathione; Magnetic Resonance Spectroscopy; Male; Me | 2018 |
The metabolome as a biomarker of mortality risk in the common marmoset.
Topics: Aging; Animal Husbandry; Animals; Betaine; Biomarkers; Callithrix; Female; Male; Metabolome; Methion | 2019 |
Betaine attenuates lysophosphatidylcholine-mediated adhesion molecules in aged rat aorta: modulation of the nuclear factor-κB pathway.
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aorta; Betaine; Cell Adhesion | 2013 |
Effects of carnosine plus vitamin E and betaine treatments on oxidative stress in some tissues of aged rats.
Topics: Aging; Animals; Antioxidants; Betaine; Body Weight; Brain; Carnosine; Glutathione; Lipid Peroxidatio | 2013 |
Prenatal betaine exposure alleviates corticosterone-induced inhibition of CYP27A1 expression in the liver of juvenile chickens associated with its promoter DNA methylation.
Topics: Aging; Animals; Animals, Newborn; Anti-Inflammatory Agents; Betaine; Blotting, Western; Chickens; Ch | 2017 |
Elevated tissue betaine contents in developing rats are due to dietary betaine, not to synthesis.
Topics: Aging; Animals; Betaine; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Female; Male; | 2008 |
Plasma free choline, betaine and cognitive performance: the Hordaland Health Study.
Topics: Aged; Aging; Betaine; Biomarkers; Choline; Choline Deficiency; Cognitive Dysfunction; Cohort Studies | 2013 |
Betaine suppresses proinflammatory signaling during aging: the involvement of nuclear factor-kappaB via nuclear factor-inducing kinase/IkappaB kinase and mitogen-activated protein kinases.
Topics: Aging; Animals; Anti-Inflammatory Agents; Betaine; Cells, Cultured; Cyclooxygenase 2; Enzyme Activat | 2005 |
Hepatic very-low-density lipoprotein and apolipoprotein B production are increased following in vivo induction of betaine-homocysteine S-methyltransferase.
Topics: Aging; Animals; Apolipoproteins B; Betaine; Betaine-Homocysteine S-Methyltransferase; Diet; Enzyme I | 2006 |
Betaine modulates age-related NF-kappaB by thiol-enhancing action.
Topics: Aging; Animals; Antioxidants; Betaine; Blotting, Western; Body Weight; Cell Nucleus; Cells, Cultured | 2007 |
Methotrexate effects on hepatic betaine levels in choline-supplemented and choline-deficient rats.
Topics: Aging; Animals; Betaine; Choline; Choline Deficiency; Liver; Male; Methionine; Methotrexate; Rats; R | 1982 |
gamma-Butyrobetaine hydroxylase activity is not rate limiting for carnitine biosynthesis in the human infant.
Topics: Adolescent; Adult; Aged; Aging; Betaine; Carnitine; Child, Preschool; Female; gamma-Butyrobetaine Di | 1987 |
[Cholagogic effect of trimethylglycine in normal animals of different ages and in experimental atherosclerosis].
Topics: Aging; Animals; Arteriosclerosis; Betaine; Bile; Cholagogues and Choleretics; Cholic Acids; Dehydroc | 1987 |
Methionine metabolism in mammals. Regulation of homocysteine methyltransferases in rat tissue.
Topics: Aging; Alloxan; Animals; Betaine; Chromatography, Gel; Cycloheximide; Cysteine; Dactinomycin; Dietar | 1971 |