betahistine has been researched along with Pulsatile Tinnitus in 27 studies
Betahistine: A histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers.
betahistine : An aminoalkylpyridine that is pyridine substituted by a 2-(methylamino)ethyl group at position 2. It acts as a histamine agonist and a vasodilator, and is thought to improve the microcirculation of the labyrinth, resulting in reduced endolymphatic pressure. It is used (generally as the hydrochloride or mesylate salt) to reduce the symptoms of vertigo, tinnitus, and hearing loss associated with Meniere's disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effectiveness of betahistine in the treatment of primary tinnitus." | 9.69 | A triple blind, placebo controlled, randomised controlled trial of betahistine dihydrochloride in the treatment of primary tinnitus. ( Castilho, GL; Dias, NH; Martins, RHG, 2023) |
| " One study with a low risk of bias found no significant difference between the betahistine groups and placebo with respect to vertigo after a long-term follow-up period." | 9.22 | Betahistine in Ménière's Disease or Syndrome: A Systematic Review. ( Bruintjes, T; van Benthem, PP; van der Zaag-Loonen, H; Van Esch, B, 2022) |
| "The aim of the study is to evaluate the effectiveness of ozone and betahistine treatments in the treatment of tinnitus." | 9.17 | The evaluation of ozone and betahistine in the treatment of tinnitus. ( Aydın, M; Külahlı, I; Sahin, MI; Sönmez, O; Vural, A, 2013) |
| "To determine whether Betahistine mesilate is effective in treating tinnitus." | 9.12 | [Efficacy of Betahistine Mesilate combined with Flunarizine Hydrochloride for treating tinnitus]. ( Lü, JQ; Ma, FR; Xin, Y; Zhao, YM, 2006) |
| "To evaluate the effectiveness of betahistine in the treatment of primary tinnitus." | 5.69 | A triple blind, placebo controlled, randomised controlled trial of betahistine dihydrochloride in the treatment of primary tinnitus. ( Castilho, GL; Dias, NH; Martins, RHG, 2023) |
| " One study with a low risk of bias found no significant difference between the betahistine groups and placebo with respect to vertigo after a long-term follow-up period." | 5.22 | Betahistine in Ménière's Disease or Syndrome: A Systematic Review. ( Bruintjes, T; van Benthem, PP; van der Zaag-Loonen, H; Van Esch, B, 2022) |
| "The aim of the study is to evaluate the effectiveness of ozone and betahistine treatments in the treatment of tinnitus." | 5.17 | The evaluation of ozone and betahistine in the treatment of tinnitus. ( Aydın, M; Külahlı, I; Sahin, MI; Sönmez, O; Vural, A, 2013) |
| "To determine whether Betahistine mesilate is effective in treating tinnitus." | 5.12 | [Efficacy of Betahistine Mesilate combined with Flunarizine Hydrochloride for treating tinnitus]. ( Lü, JQ; Ma, FR; Xin, Y; Zhao, YM, 2006) |
| "A double-blind triple cross-over trial was designed for 21 patients suffering from tinnitus; mexiletine, diazapam, betahistine and placebo were taken each for a month sequentially during which time the patients recorded their tinnitus loudness subjectively on a visual analogue scale." | 5.05 | Oral chemotherapy in tinnitus. ( Kay, NJ, 1981) |
| "In a prospective study aimed at the cure of tinnitus due to blast injury, oral treatment of 172 patients with the mono-substances Betahistine, Pentoxifyllin and Xantinol-nicotinate were compared with those of control patients who received no medications." | 5.04 | [The therapy of tinnitus resulting from blast injury (author's transl)]. ( Jakobs, P; Martin, G, 1978) |
| "From 2001 to 2006, we performed a retrospective study of patients suffering from chronic unilateral or bilateral tinnitus that was previously ineffectively treated by oral drugs [betahistine (Betaserc), extract of Ginkgo biloba (EGb 761), tanakan (Tebokan), and cinnarizine-dimenhydrinate (Arlevert), singly or in combination]." | 3.74 | Multimodal therapy for chronic tinnitus. ( Achiemere, G; Alpini, D; Hahn, A; Klement, V; Radkova, L; Strouhal, J, 2008) |
| " The aim of our work was to analyze effectiveness of betahistine hydrochloride (Betaserc) treatment on vertigo, nausea, vomiting, tinnitus and progressive hearing loss basing on the medical assessment (interview) performed by doctors and patient's personal questionnaires as well as to collect and accumulate data about balance system disorders." | 3.73 | [Assessment of betahistine dihydrochloride effectiveness in the treatment of disturbance of balance system, based on analysis of doctors and patients questionnaires results]. ( Jurkiewicz, D; Kantor, I; Usowski, J, 2006) |
| "To evaluate patients complaining of subjective tinnitus, this study examined their response to peroral betahistine mesilate, vitamin B complex and diazepam in combination." | 3.70 | Evaluation of tinnitus patients by peroral multi-drug treatment. ( Fujimura, T; Nishizaki, K; Nobuto, Y; Ohsaki, K; Ueno, M; Wang, QC; Zheng, HX, 1998) |
| "Patients with persistent subjective tinnitus as their main symptom were recruited into the study from the outpatient clinics." | 2.79 | The effectiveness of transmeatal low-power laser stimulation in treating tinnitus. ( Narayanan, P; Ngao, CF; Raman, R; Tan, TS, 2014) |
| "In 12 patients there were recognized conductive hearing loss and they were excluded from therapy of betahistine." | 2.73 | [Therapy of tinnitus in children]. ( Drobik-Wasiewicz, K; Gryczyńska, D; Kotecki, M; Malicka, M, 2007) |
| "Vertigo was the most responsive symptom." | 2.64 | Betahistine hydrochloride in Méniére's disease. ( Frew, IJ; Menon, GN, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (37.04) | 18.7374 |
| 1990's | 1 (3.70) | 18.2507 |
| 2000's | 6 (22.22) | 29.6817 |
| 2010's | 7 (25.93) | 24.3611 |
| 2020's | 3 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Castilho, GL | 1 |
| Dias, NH | 1 |
| Martins, RHG | 1 |
| Webster, KE | 1 |
| Galbraith, K | 1 |
| Harrington-Benton, NA | 1 |
| Judd, O | 1 |
| Kaski, D | 1 |
| Maarsingh, OR | 1 |
| MacKeith, S | 1 |
| Ray, J | 1 |
| Van Vugt, VA | 1 |
| Burton, MJ | 1 |
| Van Esch, B | 1 |
| van der Zaag-Loonen, H | 1 |
| Bruintjes, T | 1 |
| van Benthem, PP | 1 |
| Bruderer, SG | 1 |
| Bodmer, D | 1 |
| Stohler, NA | 1 |
| Jick, SS | 1 |
| Meier, CR | 1 |
| Wu, V | 1 |
| Sykes, EA | 1 |
| Beyea, MM | 1 |
| Simpson, MTW | 1 |
| Beyea, JA | 1 |
| Ngao, CF | 1 |
| Tan, TS | 1 |
| Narayanan, P | 1 |
| Raman, R | 1 |
| Oz, I | 1 |
| Arslan, F | 1 |
| Hizal, E | 1 |
| Erbek, SH | 1 |
| Eryaman, E | 1 |
| Senkal, OA | 1 |
| Ogurlu, T | 1 |
| Kizildag, AE | 1 |
| Ozluoglu, LN | 1 |
| Gryczyńska, D | 1 |
| Drobik-Wasiewicz, K | 1 |
| Malicka, M | 1 |
| Kotecki, M | 1 |
| Hahn, A | 1 |
| Radkova, L | 1 |
| Achiemere, G | 1 |
| Klement, V | 1 |
| Alpini, D | 1 |
| Strouhal, J | 1 |
| James, AL | 1 |
| Thorp, MA | 1 |
| Greenberg, SL | 1 |
| Nedzelski, JM | 1 |
| Kew, TY | 1 |
| Abdullah, A | 1 |
| Sönmez, O | 1 |
| Külahlı, I | 1 |
| Vural, A | 1 |
| Sahin, MI | 1 |
| Aydın, M | 1 |
| Larikova, TI | 1 |
| Cherevikova, GM | 1 |
| Ma, FR | 1 |
| Xin, Y | 1 |
| Zhao, YM | 1 |
| Lü, JQ | 1 |
| Jurkiewicz, D | 1 |
| Kantor, I | 1 |
| Usowski, J | 1 |
| Müller, H | 1 |
| Buttkus, R | 1 |
| Kay, NJ | 1 |
| Bandtlow, O | 1 |
| Ohsaki, K | 1 |
| Ueno, M | 1 |
| Zheng, HX | 1 |
| Wang, QC | 1 |
| Nishizaki, K | 1 |
| Nobuto, Y | 1 |
| Fujimura, T | 1 |
| Jakobs, P | 1 |
| Martin, G | 1 |
| Chüden, HG | 1 |
| Wilmot, TJ | 1 |
| Menon, GN | 2 |
| Frew, IJ | 1 |
| Segers, JM | 1 |
| Boedts, D | 1 |
| Pilgramm, M | 1 |
| Schumann, K | 1 |
| Hicks, JJ | 1 |
| Hicks, JN | 1 |
| Cooley, HN | 1 |
5 reviews available for betahistine and Pulsatile Tinnitus
| Article | Year |
|---|---|
Systemic pharmacological interventions for Ménière's disease.
Topics: Adrenal Cortex Hormones; Adult; Betahistine; Diuretics; Histamine Antagonists; Humans; Meniere Disea | 2023 |
Betahistine in Ménière's Disease or Syndrome: A Systematic Review.
Topics: Betahistine; Deafness; Humans; Meniere Disease; Syndrome; Tinnitus; Vertigo | 2022 |
Approach to Ménière disease management.
Topics: Betahistine; Diet, Sodium-Restricted; Disease Management; Diuretics; Dizziness; Female; Hearing Loss | 2019 |
Menière's disease.
Topics: Acute Disease; Administration, Oral; Betahistine; Hearing Loss; Humans; Incidence; Meniere Disease; | 2007 |
Medical and noninvasive therapy for Meniere's disease.
Topics: Adrenal Cortex Hormones; Aminoglycosides; Betahistine; Diet, Sodium-Restricted; Diuretics; Hearing A | 2010 |
12 trials available for betahistine and Pulsatile Tinnitus
| Article | Year |
|---|---|
A triple blind, placebo controlled, randomised controlled trial of betahistine dihydrochloride in the treatment of primary tinnitus.
Topics: Adult; Betahistine; Brazil; Female; Hearing Aids; Humans; Male; Middle Aged; Tinnitus; Treatment Out | 2023 |
The effectiveness of transmeatal low-power laser stimulation in treating tinnitus.
Topics: Administration, Oral; Ambulatory Care; Betahistine; Combined Modality Therapy; Double-Blind Method; | 2014 |
Effectiveness of the combined hearing and masking devices on the severity and perception of tinnitus: a randomized, controlled, double-blind study.
Topics: Acoustic Stimulation; Adult; Aged; Aged, 80 and over; Betahistine; Combined Modality Therapy; Double | 2013 |
[Therapy of tinnitus in children].
Topics: Adolescent; Audiometry; Betahistine; Child; Hearing Loss, Conductive; Humans; Tinnitus; Treatment Ou | 2007 |
The evaluation of ozone and betahistine in the treatment of tinnitus.
Topics: Adult; Aged; Analysis of Variance; Betahistine; Case-Control Studies; Female; Histamine Agonists; Hu | 2013 |
[Efficacy of Betahistine Mesilate combined with Flunarizine Hydrochloride for treating tinnitus].
Topics: Adolescent; Adult; Aged; Betahistine; Double-Blind Method; Drug Therapy, Combination; Flunarizine; H | 2006 |
Oral chemotherapy in tinnitus.
Topics: Administration, Oral; Adult; Aged; Betahistine; Diazepam; Double-Blind Method; Female; Humans; Male; | 1981 |
[The therapy of tinnitus resulting from blast injury (author's transl)].
Topics: Adolescent; Adult; Betahistine; Blast Injuries; Clinical Trials as Topic; Drug Evaluation; Female; G | 1978 |
Betahistine in Ménière's disease.
Topics: Adult; Audiometry; Betahistine; Clinical Trials as Topic; Deafness; Female; Humans; Male; Meniere Di | 1976 |
Betahistine hydrochloride in Méniére's disease.
Topics: Adult; Betahistine; Clinical Trials as Topic; Female; Humans; Male; Meniere Disease; Middle Aged; Py | 1976 |
[Need for rheologically active, vasoactive and metabolically active substances in the initial treatment of acute acoustic trauma].
Topics: Adult; Betahistine; Dextrans; Drug Therapy, Combination; First Aid; Flunarizine; Hearing Loss, Noise | 1986 |
Ménière's disease.
Topics: Betahistine; Clinical Trials as Topic; Enzyme Inhibitors; Humans; Meniere Disease; Nausea; Placebos; | 1967 |
10 other studies available for betahistine and Pulsatile Tinnitus
| Article | Year |
|---|---|
Population-Based Study on the Epidemiology of Ménière's Disease.
Topics: Adolescent; Adult; Aged; Alcohol Drinking; Anxiety; Betahistine; Case-Control Studies; Comorbidity; | 2017 |
Multimodal therapy for chronic tinnitus.
Topics: Adult; Aged; Betahistine; Chronic Disease; Cinnarizine; Combined Modality Therapy; Dimenhydrinate; D | 2008 |
Duplicate internal auditory canals with facial and vestibulocochlear nerve dysfunction.
Topics: Adult; Betahistine; Constriction, Pathologic; Ear, Inner; Facial Nerve; Facial Paralysis; Hearing Lo | 2012 |
[Betaserc and improvement of life quality in war veterans].
Topics: Adult; Betahistine; Headache; Histamine Agonists; Humans; Male; Quality of Life; Russia; Sleep Wake | 2005 |
[Assessment of betahistine dihydrochloride effectiveness in the treatment of disturbance of balance system, based on analysis of doctors and patients questionnaires results].
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Betahistine; Data Collection; Dizziness; Fe | 2006 |
[Clinical experiences with betahistine].
Topics: Adult; Aged; Betahistine; Cochlea; Female; Hearing Loss; Humans; Labyrinth Diseases; Male; Middle Ag | 1983 |
[Treatment of Menière's disease in general practice].
Topics: Adult; Aged; Betahistine; Drug Evaluation; Female; Hearing Loss; Humans; Male; Meniere Disease; Midd | 1980 |
Evaluation of tinnitus patients by peroral multi-drug treatment.
Topics: Administration, Oral; Aged; Betahistine; Diazepam; Drug Therapy, Combination; Female; Follow-Up Stud | 1998 |
[Betahistine treatment of Menière's disease (author's transl)].
Topics: Betahistine; Deafness; Drug Evaluation; Female; Humans; Male; Meniere Disease; Pyridines; Tinnitus; | 1978 |
Clinical trials of betahistine hydrochloride in the treatment of Ménière's disease.
Topics: Betahistine; Drug Evaluation; Hearing Disorders; Humans; Meniere Disease; Pyridines; Tinnitus | 1975 |