betahistine has been researched along with Dizzyness in 19 studies
Betahistine: A histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers.
betahistine : An aminoalkylpyridine that is pyridine substituted by a 2-(methylamino)ethyl group at position 2. It acts as a histamine agonist and a vasodilator, and is thought to improve the microcirculation of the labyrinth, resulting in reduced endolymphatic pressure. It is used (generally as the hydrochloride or mesylate salt) to reduce the symptoms of vertigo, tinnitus, and hearing loss associated with Meniere's disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effect of betahistine add-on therapy on dizziness and anxiety symptoms of BPPV patients." | 8.31 | Effect of betahistine treatment on dizziness and anxiety symptoms of BPPV patients. ( Erdur, ZB; Evran, N, 2023) |
| "Betahistine is a clinical medication for the treatment of benign paroxysmal positional vertigo (BPPV)." | 8.12 | Betahistine alleviates benign paroxysmal positional vertigo (BPPV) through inducing production of multiple CTRP family members and activating the ERK1/2-AKT/PPARy pathway. ( Hui, J; Ji, Z; Lei, Q; Zi, D, 2022) |
| "The aim of this study was to compare the effects of betahistine with dimenhydrinate on the resolution of residual dizziness (RD) of patients with benign paroxysmal positional vertigo (BPPV) after successful Epley maneuver." | 7.96 | The Impact of Betahistine versus Dimenhydrinate in the Resolution of Residual Dizziness in Patients with Benign Paroxysmal Positional Vertigo: A Randomized Clinical Trial. ( Gerami, H; Jalali, MM; Razaghi, S; Saberi, A, 2020) |
| "This subanalysis compared the efficacy of betahistine plus piracetam dual therapy versus betahistine monotherapy using data from OSVaLD, a 3 month, open-label, observational study conducted in 2272 patients with peripheral vestibular vertigo." | 7.81 | Betahistine plus piracetam dual therapy versus betahistine monotherapy for peripheral vestibular vertigo: a confounder-corrected subanalysis of the OSVaLD study. ( Lilenko, SV; Melnikov, OA; Nauta, J; Ouwens, MJ, 2015) |
| "The aim of this study was to investigate the efficacy of trimetazidine, betahistine, and ginkgo biloba extract in the treatment of residual dizziness after successful repositioning maneuvers for benign paroxysmal positional vertigo." | 5.20 | Efficacy of medical therapy in the prevention of residual dizziness after successful repositioning maneuvers for Benign Paroxysmal Positional Vertigo (BPPV). ( Acar, B; Buran, Y; Karasen, RM, 2015) |
| "To evaluate the effect of betahistine add-on therapy on dizziness and anxiety symptoms of BPPV patients." | 4.31 | Effect of betahistine treatment on dizziness and anxiety symptoms of BPPV patients. ( Erdur, ZB; Evran, N, 2023) |
| "Betahistine is a clinical medication for the treatment of benign paroxysmal positional vertigo (BPPV)." | 4.12 | Betahistine alleviates benign paroxysmal positional vertigo (BPPV) through inducing production of multiple CTRP family members and activating the ERK1/2-AKT/PPARy pathway. ( Hui, J; Ji, Z; Lei, Q; Zi, D, 2022) |
| "The aim of this study was to compare the effects of betahistine with dimenhydrinate on the resolution of residual dizziness (RD) of patients with benign paroxysmal positional vertigo (BPPV) after successful Epley maneuver." | 3.96 | The Impact of Betahistine versus Dimenhydrinate in the Resolution of Residual Dizziness in Patients with Benign Paroxysmal Positional Vertigo: A Randomized Clinical Trial. ( Gerami, H; Jalali, MM; Razaghi, S; Saberi, A, 2020) |
| "Patients in the betahistine and Tetrax groups showed significant improvements in Dizziness Handicap Index and fall index scores after treatment versus before treatment (p < 0." | 3.96 | The benefits of betahistine or vestibular rehabilitation (Tetrax biofeedback) on the quality of life and fall risk in patients with Ménière's disease. ( Chen, XB; Liu, JG; Liu, JL; Liu, YH, 2020) |
| "This subanalysis compared the efficacy of betahistine plus piracetam dual therapy versus betahistine monotherapy using data from OSVaLD, a 3 month, open-label, observational study conducted in 2272 patients with peripheral vestibular vertigo." | 3.81 | Betahistine plus piracetam dual therapy versus betahistine monotherapy for peripheral vestibular vertigo: a confounder-corrected subanalysis of the OSVaLD study. ( Lilenko, SV; Melnikov, OA; Nauta, J; Ouwens, MJ, 2015) |
| " The aim of our work was to analyze effectiveness of betahistine hydrochloride (Betaserc) treatment on vertigo, nausea, vomiting, tinnitus and progressive hearing loss basing on the medical assessment (interview) performed by doctors and patient's personal questionnaires as well as to collect and accumulate data about balance system disorders." | 3.73 | [Assessment of betahistine dihydrochloride effectiveness in the treatment of disturbance of balance system, based on analysis of doctors and patients questionnaires results]. ( Jurkiewicz, D; Kantor, I; Usowski, J, 2006) |
| " There were no serious adverse events reported in the study, betahistine was safe and well tolerated at all the dose levels tested." | 2.80 | Safety, tolerability and pharmacokinetics of 2-pyridylacetic acid, a major metabolite of betahistine, in a phase 1 dose escalation study in subjects with ADHD. ( Desai, PB; Gabbita, P; Moorthy, G; Sallans, L; Sallee, F; Zemlan, F, 2015) |
| "Betahistine is a weak agonist for histamine H1 receptors and strong antagonist for histamine H3 receptors." | 2.72 | [Betahistine in vestibular disorders: current concepts and perspectives]. ( Amelin, AV; Guseva, AL; Kunelskaya, NL; Lilenko, SV; Lyapin, AV; Melnikov, OA; Samartcev, IN; Voronov, VA; Zamergrad, MV; Zaytseva, OV, 2021) |
| "Dizziness is not a unique clinical picture, but rather is the unspecific symptom of numerous diseases." | 2.44 | [Frequently occurring forms of dizziness and their treatment]. ( Thömke, F, 2007) |
| "Vestibular vertigo is a primary symptom in neurootological clinical practice and is common among cerebrovascular diseases." | 1.32 | Investigation of Betaserc in auditory and vestibular disturbances. ( Datcov, E; Petrova, D; Sachansca, T, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 8 (42.11) | 24.3611 |
| 2020's | 6 (31.58) | 2.80 |
| Authors | Studies |
|---|---|
| Hui, J | 1 |
| Lei, Q | 1 |
| Ji, Z | 1 |
| Zi, D | 1 |
| Erdur, ZB | 1 |
| Evran, N | 1 |
| Jalali, MM | 1 |
| Gerami, H | 1 |
| Saberi, A | 1 |
| Razaghi, S | 1 |
| Liu, JL | 1 |
| Liu, JG | 1 |
| Chen, XB | 1 |
| Liu, YH | 1 |
| Wu, PX | 1 |
| Liu, JP | 1 |
| Wang, WQ | 1 |
| Li, HW | 1 |
| Zamergrad, MV | 1 |
| Kunelskaya, NL | 1 |
| Guseva, AL | 1 |
| Amelin, AV | 1 |
| Lilenko, SV | 2 |
| Samartcev, IN | 1 |
| Zaytseva, OV | 1 |
| Melnikov, OA | 2 |
| Voronov, VA | 1 |
| Lyapin, AV | 1 |
| Wu, P | 1 |
| Cao, W | 1 |
| Hu, Y | 1 |
| Li, H | 1 |
| Wu, V | 1 |
| Sykes, EA | 1 |
| Beyea, MM | 1 |
| Simpson, MTW | 1 |
| Beyea, JA | 1 |
| Moorthy, G | 1 |
| Sallee, F | 1 |
| Gabbita, P | 1 |
| Zemlan, F | 1 |
| Sallans, L | 1 |
| Desai, PB | 1 |
| Nauta, J | 1 |
| Ouwens, MJ | 1 |
| Acar, B | 1 |
| Karasen, RM | 1 |
| Buran, Y | 1 |
| Duma, SN | 1 |
| Shcherbakova, LV | 1 |
| Maarsingh, OR | 1 |
| Schellevis, FG | 1 |
| van der Horst, HE | 1 |
| Vasyl'chuk, IS | 1 |
| Kozlova, OO | 1 |
| Trinus, KF | 1 |
| Holovchenko, IuI | 1 |
| Slobodin, TM | 1 |
| Petrova, D | 1 |
| Sachansca, T | 1 |
| Datcov, E | 1 |
| Odinak, MM | 1 |
| Kovalenko, AP | 1 |
| Jurkiewicz, D | 1 |
| Kantor, I | 1 |
| Usowski, J | 1 |
| Thömke, F | 1 |
| Curley, JW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Oculomotor and Vestibular Ocular Reflex Exercises on Vertigo, Dizziness and Balance in Patients With Benign Paroxysmal Positional Vertigo[NCT05333198] | 32 participants (Actual) | Interventional | 2021-02-15 | Completed | |||
| The Effect of Vestibular Exercise, With or Without Medication, in Managing Residual Dizziness After Successful Repositioning Maneuvers in Patients With Benign Paroxysmal Positional Vertigo[NCT03624283] | 183 participants (Anticipated) | Interventional | 2018-09-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for betahistine and Dizzyness
| Article | Year |
|---|---|
[Betahistine in vestibular disorders: current concepts and perspectives].
Topics: Benign Paroxysmal Positional Vertigo; Betahistine; Dizziness; Humans; Meniere Disease; Vestibular Di | 2021 |
Approach to Ménière disease management.
Topics: Betahistine; Diet, Sodium-Restricted; Disease Management; Diuretics; Dizziness; Female; Hearing Loss | 2019 |
[Frequently occurring forms of dizziness and their treatment].
Topics: Amines; Anticonvulsants; Betahistine; Carbamazepine; Cyclohexanecarboxylic Acids; Diagnosis, Differe | 2007 |
6 trials available for betahistine and Dizzyness
10 other studies available for betahistine and Dizzyness
| Article | Year |
|---|---|
Betahistine alleviates benign paroxysmal positional vertigo (BPPV) through inducing production of multiple CTRP family members and activating the ERK1/2-AKT/PPARy pathway.
Topics: Animals; Benign Paroxysmal Positional Vertigo; Betahistine; Dizziness; Humans; MAP Kinase Signaling | 2022 |
Effect of betahistine treatment on dizziness and anxiety symptoms of BPPV patients.
Topics: Benign Paroxysmal Positional Vertigo; Betahistine; Dizziness; Humans; Quality of Life; Treatment Out | 2023 |
The Impact of Betahistine versus Dimenhydrinate in the Resolution of Residual Dizziness in Patients with Benign Paroxysmal Positional Vertigo: A Randomized Clinical Trial.
Topics: Adolescent; Adult; Aged; Benign Paroxysmal Positional Vertigo; Betahistine; Dimenhydrinate; Dizzines | 2020 |
The benefits of betahistine or vestibular rehabilitation (Tetrax biofeedback) on the quality of life and fall risk in patients with Ménière's disease.
Topics: Accidental Falls; Adult; Aged; Betahistine; Biofeedback, Psychology; Case-Control Studies; Combined | 2020 |
Betahistine plus piracetam dual therapy versus betahistine monotherapy for peripheral vestibular vertigo: a confounder-corrected subanalysis of the OSVaLD study.
Topics: Adult; Aged; Betahistine; Dizziness; Female; Humans; Male; Middle Aged; Odds Ratio; Piracetam; Vasod | 2015 |
Looks vestibular: irrational prescribing of antivertiginous drugs for older dizzy patients in general practice.
Topics: Aged; Aged, 80 and over; Betahistine; Cinnarizine; Dizziness; Female; General Practice; Histamine An | 2012 |
[Vertigo: patient management tactics].
Topics: Adult; Betahistine; Diagnosis, Differential; Dizziness; Female; Histamine Agonists; Humans; Male; Tr | 2012 |
Investigation of Betaserc in auditory and vestibular disturbances.
Topics: Adult; Audiometry; Auditory Diseases, Central; Auditory Pathways; Betahistine; Dizziness; Electronys | 2004 |
[Assessment of betahistine dihydrochloride effectiveness in the treatment of disturbance of balance system, based on analysis of doctors and patients questionnaires results].
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Betahistine; Data Collection; Dizziness; Fe | 2006 |
The treatment of peripheral dizziness.
Topics: Antiemetics; Betahistine; Dizziness; Endolymphatic Sac; Humans; Labyrinth Diseases; Meniere Disease; | 1984 |