Page last updated: 2024-10-23

betahistine and Air Sickness

betahistine has been researched along with Air Sickness in 6 studies

Betahistine: A histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers.
betahistine : An aminoalkylpyridine that is pyridine substituted by a 2-(methylamino)ethyl group at position 2. It acts as a histamine agonist and a vasodilator, and is thought to improve the microcirculation of the labyrinth, resulting in reduced endolymphatic pressure. It is used (generally as the hydrochloride or mesylate salt) to reduce the symptoms of vertigo, tinnitus, and hearing loss associated with Meniere's disease.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this investigation was to evaluate the efficacy of the histaminergic drug "Betahistine dihydrochloride" in experimental motion sickness in 10 healthy volunteers (mean age 19."3.74Efficacy of histaminergic drugs in experimental motion sickness. ( Matsnev, EI; Sigaleva, EE, 2007)
"Betahistine was evaluated for the prevention of seasickness in a laboratory and sea study."2.71Evaluation of betahistine for the prevention of seasickness: effect on vestibular function, psychomotor performance and efficacy at sea. ( Doweck, I; Gonen, A; Gordon, CR; Nachum, Z; Shupak, A; Spitzer, O, 2003)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's4 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Matsnev, EI1
Sigaleva, EE2
Gordon, CR1
Doweck, I1
Nachum, Z1
Gonen, A1
Spitzer, O1
Shupak, A1
Mantsev, EI1
Wang, JJ1
Dutia, MB1
Mierzwinski, J1
Kazmierczak, H1
Pawlak-Osinska, K1
Piziewicz, A1
Wood, CD1
Graybiel, A1

Trials

1 trial available for betahistine and Air Sickness

ArticleYear
Evaluation of betahistine for the prevention of seasickness: effect on vestibular function, psychomotor performance and efficacy at sea.
    Journal of vestibular research : equilibrium & orientation, 2003, Volume: 13, Issue:2-3

    Topics: Adult; Betahistine; Cross-Over Studies; Disease Susceptibility; Double-Blind Method; Histamine Agoni

2003

Other Studies

5 other studies available for betahistine and Air Sickness

ArticleYear
Efficacy of histaminergic drugs in experimental motion sickness.
    Journal of vestibular research : equilibrium & orientation, 2007, Volume: 17, Issue:5-6

    Topics: Adolescent; Adult; Betahistine; Coriolis Force; Histamine Agents; Humans; Male; Motion Sickness; Nys

2007
[Efficacy of betaserk in experimental motor disease].
    Vestnik otorinolaringologii, 2005, Issue:6

    Topics: Adolescent; Adult; Betahistine; Histamine Agonists; Humans; Motion Sickness; Reference Values; Treat

2005
Effects of histamine and betahistine on rat medial vestibular nucleus neurones: possible mechanism of action of anti-histaminergic drugs in vertigo and motion sickness.
    Experimental brain research, 1995, Volume: 105, Issue:1

    Topics: Animals; Betahistine; Dose-Response Relationship, Drug; Histamine; Motion Sickness; Ranitidine; Rats

1995
The effect of betahistine on vestibular habituation: comparison of rotatory and sway habituation training.
    Acta oto-laryngologica, 2001, Volume: 121, Issue:5

    Topics: Animals; Betahistine; Cimetidine; Clemastine; Columbidae; Habituation, Psychophysiologic; Histamine

2001
Evaluation of antimotion sickness drugs: a new effective remedy revealed.
    Aerospace medicine, 1970, Volume: 41, Issue:8

    Topics: Adolescent; Adult; Amine Oxidase (Copper-Containing); Betahistine; Dextroamphetamine; Ephedrine; Eth

1970