betadex and Migraine-Disorders

betadex has been researched along with Migraine-Disorders* in 2 studies

Other Studies

2 other study(ies) available for betadex and Migraine-Disorders

Article	Year
The role of caveolae in regulating calcitonin receptor-like receptor subcellular distribution in vascular smooth muscle cells. Biochemistry and cell biology = Biochimie et biologie cellulaire, 2013, Volume: 91, Issue:5 To determine whether caveolae and caveolin-1 affect the distribution of calcitonin receptor-like receptors (CLR) in vascular smooth muscle cell (VSMC) membranes, we have used VSMCs cell line A10. We found that calcitonin gene-related peptide (CGRP) reduced CLR protein in the VSMC membrane in a time-dependent manner, which was dramatically decreased after 4 h CGRP treatment, and remained at a low level after 16 h. CGRP8-37 or β-cyclodextrin (β-CD) blocked this effect, without changing the total levels of CLR protein and mRNA in the cells. Co-immunoprecipitation experiments showed that CLR bound to caveolin-1 in cell membrane fractions. Confocal laser microscopic studies confirmed this co-localization relationship at the cell plasma membrane. Thus, our data indicate that the structural integrity of caveolae plays an important role in regulating subcellular distribution of CLR. Topics: Animals; beta-Cyclodextrins; Calcitonin Gene-Related Peptide; Calcitonin Receptor-Like Protein; Caveolae; Caveolin 1; Cell Line; Cell Membrane; Mice; Migraine Disorders; Miotics; Morphine; Muscle, Smooth, Vascular; Peptide Fragments; Protein Binding; RNA, Messenger; Sequestering Agents; Signal Transduction	2013
Hemicrania continua: a case responsive to piroxicam-beta-cyclodextrin. Headache, 1992, Volume: 32, Issue:1 The case of a 53-year-old woman is described, who since the age of 38 years had been suffering from a unilateral headache that was at first remitting, but then evolved into an unremitting course. The headache was burning in quality, located in the left forehead and face, and was accompanied by mild ipsilateral autonomic symptoms. The clinical picture, as well as the absolute response to indomethacin, suggested a diagnosis of hemicrania continua. The presence of mild gastric discomfort on continuous indomethacin administration made us transfer the patient to another NSAID (piroxicam-beta-cyclodextrin). With this drug, complete relief and good tolerability was obtained. Topics: beta-Cyclodextrins; Chronic Disease; Cyclodextrins; Drug Combinations; Female; Humans; Indomethacin; Middle Aged; Migraine Disorders; Piroxicam; Stomach Diseases	1992

Article

Year

The role of caveolae in regulating calcitonin receptor-like receptor subcellular distribution in vascular smooth muscle cells.

Biochemistry and cell biology = Biochimie et biologie cellulaire, 2013, Volume: 91, Issue:5

To determine whether caveolae and caveolin-1 affect the distribution of calcitonin receptor-like receptors (CLR) in vascular smooth muscle cell (VSMC) membranes, we have used VSMCs cell line A10. We found that calcitonin gene-related peptide (CGRP) reduced CLR protein in the VSMC membrane in a time-dependent manner, which was dramatically decreased after 4 h CGRP treatment, and remained at a low level after 16 h. CGRP8-37 or β-cyclodextrin (β-CD) blocked this effect, without changing the total levels of CLR protein and mRNA in the cells. Co-immunoprecipitation experiments showed that CLR bound to caveolin-1 in cell membrane fractions. Confocal laser microscopic studies confirmed this co-localization relationship at the cell plasma membrane. Thus, our data indicate that the structural integrity of caveolae plays an important role in regulating subcellular distribution of CLR.

Topics: Animals; beta-Cyclodextrins; Calcitonin Gene-Related Peptide; Calcitonin Receptor-Like Protein; Caveolae; Caveolin 1; Cell Line; Cell Membrane; Mice; Migraine Disorders; Miotics; Morphine; Muscle, Smooth, Vascular; Peptide Fragments; Protein Binding; RNA, Messenger; Sequestering Agents; Signal Transduction

2013

Hemicrania continua: a case responsive to piroxicam-beta-cyclodextrin.

Headache, 1992, Volume: 32, Issue:1

The case of a 53-year-old woman is described, who since the age of 38 years had been suffering from a unilateral headache that was at first remitting, but then evolved into an unremitting course. The headache was burning in quality, located in the left forehead and face, and was accompanied by mild ipsilateral autonomic symptoms. The clinical picture, as well as the absolute response to indomethacin, suggested a diagnosis of hemicrania continua. The presence of mild gastric discomfort on continuous indomethacin administration made us transfer the patient to another NSAID (piroxicam-beta-cyclodextrin). With this drug, complete relief and good tolerability was obtained.

Topics: beta-Cyclodextrins; Chronic Disease; Cyclodextrins; Drug Combinations; Female; Humans; Indomethacin; Middle Aged; Migraine Disorders; Piroxicam; Stomach Diseases

1992